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CAS 97322-87-7 Troglitazone
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CAS 97322-87-7 Troglitazone

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Chemical Formula: C24H27NO5S
Exact Mass: 441.16
Molecular Weight: 441.54
m/z: 441.16 (100.0%), 442.16 (26.0%), 443.16 (4.5%), 443.17 (2.7%), 444.16 (1.2%), 443.17 (1.0%)
Elemental Analysis: C, 65.29; H, 6.16; N, 3.17; O, 18.12; S, 7.26

Troglitazone is used in the treatment of diabetes mellitus. It can reduce gluconeogenesis, improve the sensitivity of the liver to insulin and increase the liver's glucose uptake. It can also improve the insulin mediated clearance of peripheral glucose, reduce the output of glucose and the synthesis of triacylglycerol in the liver, increase the absorption and utilization of glucose in skeletal muscle, and reduce the output of fatty acids in adipose tissue. Its hypoglycemic effect is strong, does not increase weight, but also conducive to triacylglycerol and cholesterol tend to be normal, less adverse reactions, with "blockbuster" potential.

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