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Is production and trading of n-isopropylbenzylamine legal?
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Is production and trading of n-isopropylbenzylamine legal?

Views:0     Author:Site Editor     Publish Time: 2021-10-08      Origin:Site

Big bar organic n-isopropylbenzylamine is not a rare chemical, in fact, you can find it in many chemical plants. As an effective pharmaceutical intermediate, transparent N-IBA powder has also contributed to human health. However, because high purity N-IBA crystal is an isomer of methamphetamine, its legality has been questioned by many people. Unlike its "brother", in fact, its production and trading are completely legal.


Here is the content list:

l Does n-isopropylbenzylamine belong to strictly controlled chemicals?

l How to tell differences between MA and N-IBA?

l What is the significance of N-IBA analysis method?


Does n-isopropylbenzylamine belong to strictly controlled chemicals?

Because n-isopropylbenzylamine can become a precursor of certain drugs, it is usually used as an intermediate in the pharmaceutical industry. N-IBA can also be used as an anti-rust agent, which can penetrate into rust, corrosive substances, and oil stains so as to easily remove which on screws and bolts.

Under normal temperature conditions, N-IBA is a colorless or light-yellow bar crystal. Its physical properties are very similar to those of methamphetamine, and their appearance is very similar. Therefore, in recent years, n-isopropylbenzylamine is often used for adulteration of drugs.

The current research has not found that n-isopropylbenzylamine has excitatory effects or addictive ability, so it is not a nationally controlled species.

On the contrary, MA belongs to the first class of psychotropic drugs strictly controlled by the country, which has a central nervous system excitatory effect and is highly addictive. The hydrochloride of MA is crystal or powder like N-IBA, and it is the most frequently seized species in drug crimes.


How to tell differences between MA and N-IBA?

Although studies have shown that N-IBA benzylamine does not have any excitatory effects when abused at the same dose as MA, its pharmacological effects are still unknown when higher doses are abused in humans. At the same time, since the country has not yet controlled N-IBA, the crackdown on drug trafficking will be smaller, and it may be used by drug dealers.

In drug crime cases, the number of drugs is directly related to sentencing. MA and N-IBA are controlled drugs and non-controlled chemical raw materials, but they are easily confused during testing, causing false positives.

Therefore, a clear distinction between the two and quantitative analysis is of great significance to the judgment of the nature of the case and the sentencing. After several years of research, the following method was used to distinguish the two:

l Infrared spectrum analysis

Infrared spectroscopy is a good qualitative identification method. According to the position, intensity and shape of the characteristic absorption peak of the infrared spectrum, take the relationship between the vibration frequency of the group and the molecular structure into consideration, and then determine the group or bond contained in the molecule, it can be preliminarily judged whether the substance containing MA or N-IBA.

l GCMS analysis

The gas chromatography-mass spectrometry method is usually used for the qualitative identification and quantitative analysis of gasifiable substances. In the detection of unknowns, GCMS is the most commonly used method.

Because gas chromatography can separate the mixture of N-IBA and MA at a certain temperature, and then use mass spectrometry as a detector to qualitatively analyze the separated components.

l HPLC analysis

At a slightly higher concentration, it is difficult for gas chromatography to effectively separate MA and N-IBA, because in gas chromatography, if the sample concentration is slightly higher, it will produce stronger tailing.

In this case, it is difficult for the experimenter to directly determine the preliminary characterization of the N-IBA mixture through the retention time. Therefore, the separation and analysis of N-IBA mixed components by liquid chromatography is the routine next step.

Since not all anti-drug laboratories are equipped with liquid chromatography-mass spectrometers, the most effective method for distinguishing methamphetamine and n-isopropylbenzylamine is still HPLC analysis.


What is the significance of N-IBA analysis method?

In summary, although N-IBA doped MA is difficult to identify by crystalline morphology, the main differences between the two can be identified through Infrared spectroscopy, GCMS and HPLC.

According to related reports, MA is the most popular and easily available drug. Although the production and trading of N-IBA are completely legal, those suspected of manufacturing, transporting and possessing MA will face severe penalties.

Since the use of N-IBA is legal, misuse of N-IBA for MA may lead to serious consequences. With the advancement of inspection and analysis methods, the distinction between the two will become easier and more precise, which provides some operational conditions for anti-drug practice.


As a professional manufacturer of organic n-isopropylbenzylamine big bar that strictly abides by the law, Shaanxi BLOOM TECH Co., Ltd. is trusted by customers all over the world. We hope to let more people know about the rich applications, and also remind consumers not to use crystalline n-isopropylbenzylamine for illegal transactions. If you want to get more information about high purity N-IBA powder, please feel free to contact our customer service.



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