Eriodictyol(link:https://www.bloomtechz.com/synthetic-chemical/api-researching-only/eriodictyol-powder-cas-552-58-9.html) is light yellow powder and has various pharmacological activities, such as anti-oxidation, anti-inflammation, analgesic and other activities, as well as diuretic, improving diabetes and diabetic complications. Antioxidants. Widely present in citrus fruits, vegetables and many medicinal plants, it has antioxidant, anti-inflammatory and neuroprotective effects, so it has potential value for use in pharmaceutical, nutraceutical or food industries. At present, the main ways to obtain eriodictyol are extraction from plants or chemical synthesis. The use of engineered microorganisms to produce eriodictyol is not affected by seasonal changes. It has the functions of anti-oxidation, anti-inflammation, analgesia, and improvement of diabetes and diabetic complications. Studies have found that eriodictyol can effectively protect keratinocytes from UV-induced death by inhibiting the cleavage of pro-caspase-3 or pro-caspase-9 and the release of cytochrome C.
Eriodictyol is a natural flavonoid with a wide range of applications. The various uses of Eriodictyol are described in detail below.
1. Protect the digestive system:
Eriodictyol has been studied for the care and promotion of digestive health. It has the following effects:
- Anti-inflammatory effect: Eriodictyol has an anti-inflammatory effect that reduces inflammation in the gastrointestinal tract. Inflammation is one of the main pathological processes of some digestive system diseases such as gastric ulcer and inflammatory bowel disease.
- Anti-ulcer activity: Eriodictyol was found to be protective against gastric ulcers. It relieves damage to the gastric mucosa and promotes the healing of gastric ulcers.
- Antibacterial effect: Eriodictyol has an inhibitory effect on some common pathogenic bacteria in the digestive system, including Escherichia coli and Helicobacter pylori. This antimicrobial activity helps prevent gastrointestinal problems caused by bacterial infections.
- Regulate intestinal motility: Eriodictyol can regulate intestinal peristalsis and digestive function, helping to improve the normal functioning of the digestive system.
2. Promotes bone health:
Eriodictyol has some potential benefits for bone health. Here's what a few of them do:
- Anti-inflammatory effect: Eriodictyol has anti-inflammatory activity that reduces inflammation around the bones. This is especially important for inflammatory bone diseases like osteoporosis and arthritis.
- Antioxidant effect: As a powerful antioxidant, Eriodictyol can neutralize free radicals and reduce the occurrence of oxidative damage in bone tissue. This helps maintain the health of bone cells and reduces the risk of bone loss.
- Calcium Absorption Promotion: Studies have shown that Eriodictyol can increase the absorption rate of calcium in the body, thus helping to maintain bone density and bone health.
- Cytoprotection: Eriodictyol protects bone cells from damage, inhibits the destructive bone resorption process, and promotes osteogenesis.
3. Improves learning and memory: Some studies suggest that Eriodictyol may help improve learning and memory. It can affect the release and signaling of neurotransmitters, thereby enhancing the learning and memory formation processes.
4. Improved blood circulation: Good blood circulation is essential to maintain normal cognitive function. Eriodictyol is thought to improve blood circulation, providing an adequate supply of oxygen and nutrients to the brain, thereby improving cognitive function.
5. Anti-stress effect: long-term stress response negatively affects cognitive function. Eriodictyol has anti-stress effects, which can reduce the damage of stress to the brain and maintain a normal cognitive state.
6. As free radical receptors and chain terminators, flavonoids can exert antioxidant activity. The position and brightness of photoradicals have an important relationship with the antioxidant capacity of flavonoids. The flavonoids with o-diphenol free radicals in the ring have the strongest antioxidant activity. According to the chemical structure of pyrogallol, pyrogallol is a flavone with ortho-diphenol light group on the ring, and pyrogallol is a potential natural antioxidant with strong antioxidant activity.
7. In addition, it is also effective in preventing induced protein, lipid and oxidative damage. Its protective effect may be to inhibit the attack of free radicals on biological macromolecules by scavenging free radicals, indicating that it has good antioxidant activity. The study found that carnosol can significantly inhibit the activity of liver cancer cells, which may be through its antioxidant effect to lower the content of free radicals below the physiological level, thereby inhibiting the activity of liver cancer cells.
8. Using the aromatic amino acid L-tyrosine (L-tyrosine) as the carbon source, it is metabolized in Escherichia coli.
9. Antibacterial agent:
Eriodictyol has antibacterial activity against a wide variety of bacteria and fungi, including resistant strains. Therefore, it can be used in the development of antibacterial agents, disinfectants and skin care products.
10. Antidiabetic agents:
Eriodictyol can help control blood sugar levels by increasing insulin sensitivity, inhibiting glycolysis, and regulating blood glucose metabolic pathways. Therefore, it is studied for the development of drugs to treat diabetes and regulate blood sugar.
11. Cardiovascular protective agents:
Eriodictyol has a protective effect on the cardiovascular system and reduces the risk of heart attacks. It works by enhancing vascular endothelial function, inhibiting platelet aggregation and reducing vascular inflammation.
12. Neuroprotective agents:
Eriodictyol has been shown to have protective effects on the nervous system and may reduce the symptoms of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. It works by reducing oxidative stress, suppressing neuroinflammation, and modulating nerve cell signaling.
13. Antioxidants:
Eriodictyol has significant antioxidant activity, which can neutralize free radicals and reduce oxidative stress and oxidative damage. Therefore, it is widely used in health care products, skin care products and anti-aging products.
Eriodictyol has the functions of anti-oxidation, anti-inflammation, analgesia, and improvement of diabetes and diabetic complications (. Some studies have found that eriodictyol can inhibit the cleavage of pro-caspase-3 or pro-caspase-9 and the release of cytochrome C , effectively protects the death of keratinocytes induced by ultraviolet rays.Eriodictymol can be antibacterial and anti-inflammatory, and plays a vital role in the pathogenesis of diabetes, and can inhibit the induction of immunoglobulin E (Ig E)/antigen (Ag) Type allergic reaction, also has analgesic and warming effect.