Larocaine hydrochloride, also known as lidocaine hydrochloride, is a widely used local anesthetic and anti - arrhythmic agent. In this blog, we'll explore its chemical formula, properties, uses, and more. As a reliable larocaine hydrochloride supplier, I'm eager to share in - depth knowledge about this important compound with you.
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Larocaine Hydrochloride
Product Code: BM-2-5-010
English Name: Larocaine Hydrochloride
CAS No.: 553-63-9
Molecular formula: c16h26n2o2.clh
Molecular weight: 314.854
EINECS No.: 202-303-5
Enterprise standard: HPLC>99.0%, HNMR
Main market: USA, Australia, Brazil, Japan, Germany, Canada etc.
Manufacturer: BLOOM TECH Wuxi Factory
Technology service: R&D Dept.-1
Shipping: Shipping as another no sensitive chemical compound name.
We provide Larocaine Hydrochloride, please refer to the following website for detailed specifications and product information.
Product:https://www.bloomtechz.com/synthetic-chemical/api-researching-only/pure-tetracaine-94-24-6.html
Chemical Formula of Larocaine Hydrochloride
The chemical formula of larocaine hydrochloride is (C_{14}H_{22}N_{2}O\cdot HCl). It is an organic compound formed by the reaction of lidocaine (the base form) with hydrochloric acid. Lidocaine, with the formula (C_{14}H_{22}N_{2}O), belongs to the amide - type local anesthetics. When it reacts with hydrochloric acid ((HCl)), it forms the hydrochloride salt, which is more water - soluble and stable than the free base form.
The structure of lidocaine consists of an aromatic ring, an amide linkage, and an alkyl chain. The aromatic ring provides some lipophilicity, which is important for the penetration of cell membranes. The amide linkage is a characteristic feature of amide - type local anesthetics, differentiating them from ester - type local anesthetics. The addition of the hydrochloride group ((HCl)) to the lidocaine molecule increases its solubility in water, which is crucial for its use in various pharmaceutical formulations.
Properties of Larocaine Hydrochloride
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Physical Properties: Larocaine hydrochloride is a white crystalline powder. It has a melting point in the range of approximately 128 - 132 °C. It is freely soluble in water, ethanol, and chloroform, but insoluble in ether. These solubility properties make it suitable for formulating injections, creams, and gels for medical use.
Chemical Properties: As a hydrochloride salt, larocaine hydrochloride is relatively stable under normal storage conditions. However, it can react with strong oxidizing agents and bases. In an alkaline environment, it may undergo hydrolysis of the amide bond, which can lead to the degradation of the compound.
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Uses of Larocaine Hydrochloride
- Medical Use:
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Local Anesthesia: Larocaine hydrochloride is one of the most commonly used local anesthetics in medical and dental procedures. It works by blocking the sodium channels in nerve cells, preventing the generation and conduction of nerve impulses. This results in a loss of sensation in the area where it is applied. It can be used for minor surgical procedures, such as skin biopsies, dental extractions, and suturing of wounds.
Anti - arrhythmic Agent: In addition to its anesthetic properties, larocaine hydrochloride can also be used to treat certain types of ventricular arrhythmias. It acts on the heart muscle cells, stabilizing the electrical activity of the heart and preventing abnormal rhythms.
Veterinary Use: Larocaine hydrochloride is also used in veterinary medicine for similar purposes. It can be used for local anesthesia during surgical procedures on animals, as well as for the treatment of cardiac arrhythmias in some cases.
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Comparison with Other Compounds
In the field of pharmaceuticals, there are many other compounds with different applications. For example, Upadacitinib Powder CAS 1310726 - 60 - 3 is a Janus kinase (JAK) inhibitor used for the treatment of rheumatoid arthritis and other autoimmune diseases. It has a completely different mechanism of action compared to larocaine hydrochloride.
Letrozole Powder CAS 112809 - 51 - 5 is an aromatase inhibitor used in the treatment of breast cancer. It works by reducing the production of estrogen in the body, which is beneficial for hormone - receptor - positive breast cancer patients.
Furazolidone Powder CAS 67 - 45 - 8 is an antibacterial and antiprotozoal agent. It is used to treat various infections, such as diarrhea caused by bacteria and protozoa. These compounds have different chemical structures and therapeutic indications compared to larocaine hydrochloride.
Production and Quality Control
As a larocaine hydrochloride supplier, we follow strict production and quality control processes. The production of larocaine hydrochloride typically involves several steps, including the synthesis of lidocaine and its subsequent reaction with hydrochloric acid. The raw materials used in the production are carefully selected to ensure high - quality products.
During the production process, we monitor various parameters, such as reaction temperature, reaction time, and pH. After the synthesis, the product undergoes purification steps to remove any impurities. Quality control is carried out at multiple stages, including raw material testing, in - process testing, and final product testing. We use advanced analytical techniques, such as high - performance liquid chromatography (HPLC), infrared spectroscopy (IR), and nuclear magnetic resonance (NMR) spectroscopy, to ensure the identity, purity, and quality of the larocaine hydrochloride.
Safety and Precautions
Although larocaine hydrochloride is widely used in medicine, it should be used with caution. It can cause side effects, especially when used in high doses or in patients with certain medical conditions. Common side effects include dizziness, drowsiness, nausea, and vomiting. In rare cases, it can cause allergic reactions, seizures, and cardiac arrhythmias.
Patients should inform their healthcare providers about any allergies, medical conditions, or medications they are taking before using larocaine hydrochloride. Healthcare providers should also follow proper dosing guidelines and monitor patients closely during and after the administration of larocaine hydrochloride.
Contact for Purchase and Collaboration
If you are interested in purchasing larocaine hydrochloride or have any questions about our products, please feel free to contact us. We are committed to providing high - quality products and excellent customer service. Whether you are a pharmaceutical company, a research institution, or a medical facility, we can meet your needs for larocaine hydrochloride.
References
- Rang, H. P., Dale, M. M., Ritter, J. M., & Moore, P. (2015). Rang & Dale's Pharmacology. Elsevier.
- Goodman, L. S., & Gilman, A. G. (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics. McGraw - Hill.
- Martindale: The Complete Drug Reference. Pharmaceutical Press.