Aniracetam Capsules are a type of brain function improving medication, characterized as capsules with white to off white powder or granules. It is a synthetic nootropic (cognitive-enhancing substance) available in capsule form. It is approved as a prescription drug in some European countries and Asia, where it has been used to treat cognitive deficits following stroke, and in cases of Alzheimer's disease and dementia. It is not approved by the U.S. Food and Drug Administration (FDA) as a prescription product or a supplement, and the FDA has raised concerns about the safety and efficacy of unapproved nootropic products.
It is a cyclic derivative of gamma aminobutyric acid (GABA) that selectively acts on the central nervous system through the blood-brain barrier. It has a good promoting effect on the memory reproduction process of normal rats' discriminative learning, can counteract memory decline caused by hypoxia, and effectively improve memory disorders caused by certain reasons. At the same time, it also has cortical anti hypoxia ability, which can protect learning and memory loss caused by various chemicals such as hypercapnia, scopolamine, or electroconvulsive therapy. In addition, the fenacetam capsule partially works by protecting the function of cholinergic neurons, which can protect the brain from the decrease in acetylcholine and memory caused by scopolamine. It can also stimulate the presynaptic membrane to reabsorb choline and accelerate the synthesis of acetylcholine.
At the same time, our company not only provides pure powders, but also tablets and injections. If needed, please feel free to contact us at any time.
 |
 |
Additional information of chemical compound:
Which drugs are not suitable for simultaneous use
The research on the interaction between Aniracetam Capsules and other drugs is relatively limited, but based on their pharmacological effects, chemical structure, and the characteristics of similar drugs, the following may not be suitable for simultaneous use with the following types of drugs:
Central nervous system inhibitory drugs include barbiturates (such as phenobarbital), benzodiazepines (such as diazepam), opioid analgesics (such as morphine), etc. It can selectively act on the central nervous system, improving memory and cognitive function. And central nervous system depressants mainly exert their effects by inhibiting the excitability of the central nervous system. When both are used simultaneously, a synergistic central inhibitory effect may occur, leading to symptoms such as excessive sleepiness, dizziness, fatigue, and blurred consciousness in patients. In severe cases, it may even cause life-threatening situations such as respiratory depression and coma. Barbital drugs can enhance gamma aminobutyric acid (GABA) neurotransmission, inhibit central nervous system polysynaptic responses, reduce cellular metabolism and oxygen consumption, and suppress cerebral cortex.
Benzodiazepine drugs act on benzodiazepine receptors, enhancing the function of the central inhibitory neurotransmitter gamma aminobutyric acid receptor complex, thereby producing sedative, hypnotic, and anti anxiety effects. Opioid analgesics mainly act on opioid receptors, inhibit the release of neurotransmitters, and produce strong analgesic and central inhibitory effects. Although the mechanism of action of aniracetam is different from these drugs, when they act on the central nervous system at the same time, they may affect the balance of neurotransmitters and the activity of neurons, leading to enhanced central inhibitory effects.
Anticholinergic drugs
Anticholinergic drugs include atropine, scopolamine, and pheniramine. It's partially act by protecting the function of cholinergic neurons, stimulating the reuptake of choline by the presynaptic membrane and accelerating the synthesis of acetylcholine. And anticholinergic drugs inhibit the action of acetylcholine by blocking cholinergic receptors. When both are used simultaneously, their effects are mutually antagonistic, which may reduce the efficacy of aniracetam in improving memory and cognitive function. Atropine and other anticholinergic drugs can competitively antagonize M-cholinergic receptors, inhibiting a series of symptoms caused by parasympathetic nervous system excitation, such as smooth muscle spasms and increased glandular secretion.
Meanwhile, they also affect cholinergic transmission in the central nervous system. It's rely on normal cholinergic nerve function to exert their cognitive improvement effects, and the presence of anticholinergic drugs can interfere with this process, greatly reducing the effectiveness of the drug.
The drugs that affect hepatic enzyme activity can be divided into hepatic enzyme inducers (such as phenobarbital, rifampicin, carbamazepine, etc.) and hepatic enzyme inhibitors (such as cimetidine, ketoconazole, erythromycin, etc.). It needs to be metabolized by the liver in the body, and hepatic enzymes play a key role in the drug metabolism process. Liver enzyme inducers can accelerate the synthesis and activity of liver enzymes, accelerate the metabolic rate of fenacetam capsules, resulting in a decrease in blood drug concentration and weakened efficacy. And liver enzyme inhibitors will inhibit the activity of liver enzyme, slow down the metabolism of fenacetam capsules, increase blood drug concentration, and increase the risk of adverse drug reactions. Phenobarbital and other hepatic enzyme inducers can induce the synthesis of hepatic microsomal enzymes, increase enzyme activity, and accelerate drug metabolism.
Liver enzyme inhibitors such as cimetidine bind to the active sites of liver enzymes, inhibiting their catalytic activity and slowing down drug metabolism. The metabolic process of aniracetam is influenced by the activity of hepatic enzymes. When used in combination with hepatic enzyme inducers or inhibitors, its pharmacokinetic parameters will change, thereby affecting the efficacy and safety of the drug.
Drugs that may affect neurotransmitter balance
Such as selective serotonin reuptake inhibitors (SSRIs, such as fluoxetine, paroxetine, etc.), tricyclic antidepressants (such as amitriptyline, promethazine, etc.). These drugs mainly exert therapeutic effects by affecting the reuptake or metabolism of neurotransmitters such as serotonin and norepinephrine, thereby regulating emotions and cognitive function. It's also act on the central nervous system and may affect the balance of neurotransmitters. When both are used simultaneously, they may interfere with the normal metabolism and transmission of neurotransmitters, leading to increased adverse reactions or unstable therapeutic effects. SSRI drugs exert antidepressant effects by inhibiting the reuptake of serotonin by the presynaptic membrane, increasing the concentration of serotonin in the synaptic cleft.
Tricyclic antidepressants can inhibit the reuptake of norepinephrine and serotonin. Anisacetam capsules may affect the neurotransmitter system through multiple pathways. When used in combination with these drugs, they may alter the balance of neurotransmitters, causing a series of adverse reactions such as headaches, insomnia, anxiety, tremors, and may also affect their respective therapeutic effects.
Such as nifedipine, verapamil, etc. Although there is currently no clear evidence to suggest a direct interaction between aniracetam and calcium channel blockers, both of them act on the nervous and cardiovascular systems, and simultaneous use may have a cumulative effect on neurological and cardiovascular function, increasing the risk of adverse reactions such as hypotension and bradycardia. Such as sodium phenytoin and carbamazepine. Antiepileptic drugs mainly control epileptic seizures by regulating the excitability of neurons, and their pharmacokinetic and pharmacodynamic characteristics are relatively complex. When used together with antiepileptic drugs, the concentration of antiepileptic drugs in the blood may be affected, leading to unstable seizure control and increased adverse reactions of the capsule.
What are the side effects
Neurological side effects
Dizziness and dizziness
Dizziness and vertigo are common neurological side effects of fenacetam capsules. This may be due to the medication having a certain impact on the central nervous system, interfering with the normal balance of neurotransmitters or the normal activity of neurons. After taking medication, patients may feel dizzy and disoriented, affecting their daily activities and work efficiency. The occurrence of this symptom may be related to an individual's sensitivity to medication. Some patients may experience it in the early stages of medication, while others may gradually show symptoms after a period of medication.
Drowsiness
Sleepiness is also a common side effect. Anisacetam capsules may affect the excitability regulation mechanism of the central nervous system, leading to excessive drowsiness and increased sleep in patients. Patients may feel obvious drowsiness during the day, making it difficult to maintain a clear state of mind and affecting normal social, learning, and work activities. The degree of drowsiness varies from person to person. For some patients, it may only be mild drowsiness, while for others, it may seriously affect their quality of life.
Excitement and restlessness
Although relatively rare, some patients may experience neurological symptoms such as excitement and restlessness after using fenacetam capsules. This may be related to the complex effects of drugs on the neurotransmitter system, leading to abnormal excitation of neuronal activity. Patients may exhibit symptoms such as emotional excitement, restlessness, and difficulty sitting or standing, which not only cause physical discomfort but may also have a negative impact on their psychological state.
Other neurological symptoms
In addition to the common symptoms mentioned above, there may also be neurological side effects such as headaches and fatigue. Headaches may be caused by drug-induced cerebral vasodilation or changes in nerve tension; Fatigue may be related to the impact of medication on neuromuscular conduction, leading to patients feeling weak and lacking energy throughout the body.
Digestive system side effects
Dry mouth
Dry mouth is one of the common digestive system side effects of fenacetam capsules. Medications may affect the secretion function of oral mucosa, leading to a decrease in saliva secretion and making patients feel dry in the mouth. Dry mouth not only causes discomfort for patients, but may also affect oral hygiene, increasing the risk of dental caries and oral infections.
Decreased appetite
Reduced appetite is also a common side effect. Medications may have an impact on the neural regulation and digestive function of the gastrointestinal tract, interfering with the normal function of the appetite regulation center, leading to a decrease in patients' interest in food and a reduction in their food intake. Long term loss of appetite may lead to malnutrition, affecting the patient's physical health and recovery.
Constipation
Constipation is one of the digestive system problems that may be caused by the use of fenacetam capsules. Medications may affect the peristalsis function of the intestine, slowing down the speed of food movement in the intestine, resulting in prolonged retention of feces in the intestine, excessive absorption of water, and ultimately leading to dry and difficult bowel movements. Constipation not only causes physical pain to patients, but may also lead to other complications such as hemorrhoids and anal fissures.
Gastrointestinal discomfort
Some patients may experience gastrointestinal discomfort symptoms such as nausea, vomiting, abdominal pain, and diarrhea. Nausea and vomiting may be caused by the stimulation of gastrointestinal mucosa or the regulatory effect on gastrointestinal nerves by drugs; Abdominal pain and diarrhea may be related to factors such as abnormal intestinal peristalsis and dysbiosis of the gut microbiota. These gastrointestinal discomfort symptoms can affect the digestive function and quality of life of patients.
Frequently Asked Questions
Do I need a prescription for aniracetam?
+
-
Aniracetam (brand names Draganon, Sarpul, Ampamet, Memodrin, Referan), also known as N-anisoyl-2-pyrrolidinone, is a racetam which is sold in Europe as a prescription drug. It is not approved by the Food and Drug Administration for use in the United States as a prescription medication or dietary supplement.
What is the most effective supplement for ADHD?
+
-
Research has found the inclusion of omega-3 and omega-6 fatty acids benefits in the areas of hyperactivity, attention, or impulsivity. The Journal of Lipids reported that omega-3 and omega-6 supplements moderately decreased the severity of some ADHD symptoms, such as hyperactivity and impulsivity.
What is aniracetam made of?
+
-
Aniracetam is defined as a therapeutically important compound that is derived from pyrrolidine and possesses various pharmaceutical activities, including potential cognitive enhancement.
Hot Tags: aniracetam capsules, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, CAS 51958 51 1, 1 8 Dibromo 9H carbazole, pontocaine, Iridium III chloride, 2 chloro 4 dibenzo b d thiophen 4 yl 6 phenyl 1 3 5 triazine, diphenylcarbazide reagent