Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of marine collagen peptide capsules in China. Welcome to wholesale bulk high quality marine collagen peptide capsules for sale here from our factory. Good service and reasonable price are available.
Marine collagen peptide capsules(C00211) are high-activity functional health food formulations manufactured from deep-sea fish skin and fish scales via low-temperature compound enzymatic hydrolysis and ultrafiltration purification. Distinct from conventional forms including collagen hydrolysate powder and oral liquid, the capsule features hermetic sealing, stable bioactivity and precise dosage.This preparation can target the dermal layer of the cutis and articular cartilage tissue to deliver anti-aging repair, joint lubrication, antioxidant and immunomodulatory effects.
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Fish Collagen Peptide COA
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| Certificate of Analysis | ||
| Compound name | Fish Collagen Peptide | |
| Grade | Pharmaceutical grade | |
| CAS No. | 9064-67-9 | |
| Quantity | 45g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090056 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure | N\A | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.21% |
| Loss on drying | ≤1.0% | 0.62% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.90% |
| Single impurity | <0.8% | 0.33% |
| Total microbial count | ≤750cfu/g | 500 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 750ppm |
| Storage | Store in a sealed, dark, and dry place below 2-8°C | |
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Applications in Nutraceutical Foods and Wellness products

Sourced from aquatic by-products including deep-sea fish skin, scales and fish osseins, marine collagen peptide capsules are small-molecule active peptide preparations produced by hydrolysis and purification. Compared with terrestrial animal collagen, they boast low molecular weight, superior biocompatibility, zero zoonosis risk and favorable absorbability, ranking among staple raw materials for contemporary nutraceutical foods and wellness products. Their application scenarios cover anti-aging skincare, joint and ossein care, immune modulation and daily nutritional supplementation to accommodate health demands across all age groups.
In anti-aging skincare-focused wellness products, this ingredient dominates efficacy-driven formulations. Rich in signature collagen amino acids namely glycine, proline and hydroxyproline, it supplies building blocks for de novo collagen synthesis in the dermal layer of human cutis to mitigate cutaneous aging. Most premium oral beauty supplements adopt C00211 as the core component, compounded with auxiliary materials such as vitamin C and hyaluronic acid into compound capsules. These finished products target sagging reduction, fine line fading, complexion brightening and cutis barrier repair, catering to late-night workers, office females and middle-aged/elderly groups with progressive cutis aging, securing growing market penetration as a core oral beauty nutraceutical food category.

It enjoy extensive and well-documented efficacy in joint and ossein care nutraceutical foods. Differing from generic nutritional nutraceuticals, their small-molecule hydrolysates specifically target articular cartilaginous tissue to furnish nutrients for cartilage repair and synovial membrane maintenance. Regular quantified supplementation alleviates joint dryness, crepitus and mild arthralgia for sedentary populations, fitness enthusiasts and seniors suffering from degenerative joint conditions. Frequently formulated with chondroitin and calcium into compound joint-protective wellness products, the capsules emerge as a mainstream option within sports nutrition and geriatric healthcare sectors, matching rising consumer demand for proactive joint maintenance.
The ingredient also bears notable application value in immune-regulating and metabolic-support nutraceutical foods. Bioactive oligomers within C00211 exhibit antioxidant and anti-inflammatory properties to eliminate free radicals, alleviate oxidative cellular damage and assist innate immune regulation. Their compact molecular structure imposes minimal gastrointestinal metabolic burden, suiting daily nutrient supplementation for consumers with compromised digestive function. Benefiting from excellent emulsification and stability, C00211 serves as a nutraceutical food improver; meanwhile, the capsule's portability, accurate dosing and convenient storage fit modern fast-paced lifestyles, cementing its status as a preferred daily dietary nutraceutical format.
In Vivo Physiological Effects upon Oral Administration
Thanks to outstanding water solubility and small molecular configuration, orally ingested marine collagen peptide capsules undergo rapid gastrointestinal absorption, overcoming poor digestibility limitations of high-molecular-weight native collagen. Its multi-target physiological functions span cutaneous restoration, osteoarticular maintenance, antioxidation, anti-inflammation and ossein metabolism modulation with defined action mechanisms and targeted bioactivity.Cutis regeneration and anti-aging constitute its primary physiological benefits.
Following oral intake, circulating bioactive hydrolysates selectively accumulate in the dermis to stimulate fibroblast proliferation and accelerate endogenous collagen plus elastin synthesis, offsetting physiological collagen depletion starting from age 25. It further inhibits matrix metalloproteinase activity to slow degradation of intrinsic skin collagen, preserving structural integrity of dermal collagen and elastic fibers for enhanced cutis elasticity and wrinkle reduction. Its inherent antioxidant capacity neutralizes intracellular free radicals to counter oxidative damage triggered by ultraviolet irradiation, irregular sleep and mental stress, improving dull and dry complexions while repairing impaired epidermal barriers.


Targeted joint protection and ossein metabolism regulation represent another core physiological function. Active hydrolysates selectively accumulate within articular cartilage and synovial tissue to boost chondrocyte proliferation and cartilaginous matrix biosynthesis, repair damaged cartilage microstructure and boost synovial fluid secretion for reduced intra-articular friction and mechanical wear. In addition, it suppresses pro-inflammatory cytokine release within articular cavities to relieve mild synovitis and improve joint mobility. For ossein homeostasis, signature constituent amino acids balance osteoblast and osteoclast activities to promote ossein matrix deposition, elevate ossein mineral density and curb ossein loss, helping prevent senile osteoporosis and degenerative joint disorders among the elderly.
Moreover, C00211 delivers systemic antioxidant and immunomodulatory effects. Oral supplementation elevates bodily activities of superoxide dismutase and glutathione peroxidase while lowering malondialdehyde concentrations to scavenge excess free radicals, mitigate systemic oxidative stress and delay whole-body senescence. It modulates immune cell viability within intestinal mucosa to reinforce gut barrier function and strengthen non-specific immunity; its mild small-peptide formulation produces no gastrointestinal strain and is suitable for long-term daily oral supplementation.
Industrial production of C00211 primarily utilizes cold-water deep-sea fish such as cod and pollock for raw materials (fish skin, scales and osseins), adopting mature bioenzymatic hydrolysis as the prevailing mainstream manufacturing protocol featuring controllable production parameters, high purity and stable bioactivity.
The whole workflow is divided into four core stages: raw material pretreatment, gradient enzymatic hydrolysis, enzyme deactivation & purification, concentration and spray drying, characterized by short production cycles and high product yield.
Raw material pretreatment lays the foundation for finished product quality. Aquatic by-products are screened to discard impurities and deteriorated feedstock, repeatedly rinsed with clean water, then processed via degreasing and deodorization to remove lipids, odor-causing substances and non-collagen contaminants.
The industry widely employs mild acid-base pretreatment: raw materials are steeped under weakly alkaline conditions (pH 8–9) to strip foreign proteins and lipids without compromising natural collagen hydrolysate chains; harsh high-temperature or extreme pH treatment is avoided to protect bioactive structures. Pretreatment routinely raises raw collagen purity above 90%.
Controlled compound enzymatic hydrolysis acts as the core production step. Preprocessed feedstock is blended with purified water into slurry inside thermostatted bioreactors; reaction temperature and pH are precisely calibrated before adding a composite enzyme cocktail composed of alkaline protease, papain and pepsin for graded hydrolysis.
By tuning enzyme dosage, reaction temperature and retention time, the triple-helical structure of macromolecular collagen is selectively fragmented into homogeneous small bioactive hydrolysates confined within 1000–3000 Da to maximize intestinal absorbability. Compared with single-enzyme hydrolysis, synergistic multi-enzyme catalysis shortens production cycle to 18 hours and lifts final product yield up to 68%.
Enzyme deactivation and refining secure end-product safety and purity. Upon completion of hydrolysis, rapid thermal deactivation terminates proteolytic reactions to prevent excessive hydrolysate degradation and bioactivity loss.
The crude hydrolysate is subsequently subjected to fractional purification via 10–30 kDa ultrafiltration membranes to intercept macromolecular impurities, unhydrolyzed proteins and microorganisms, eliminating residual fishy odor and contaminants to acquire high-purity C00211 stock solution.
The refined liquid proceeds through low-temperature vacuum concentration and spray drying into fine powder, ready for direct capsule filling. Full-process low-temperature treatment optimally retains hydrolysate bioactivity, with final powder complying with industrial specifications for water solubility, stability and biological potency applicable to nutraceutical food and wellness product manufacturing.
References
- PMC. Recent Advancements in Marine Collagen: Exploring New Sources, Processing Approaches, and Nutritional Applications[J]. 2025.
- BioTong. Review: Hydrolyzed Marine Collagen: Emerging Evidence of Oral Bioavailability and Health Benefits[J]. 2026.
- Bio Absorb Nutraceuticals. Marine Collagen: The High-Bioavailability Difference[R]. 2026.
- Original Document Library. 2025–2030 Global Marine Collagen Hydrolysate Industry Trend Analysis & Strategic Investment Advisory Report[R]. 2025.
FAQ
What are the product good for?
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Studies have found that it from organisms such as fish, jellyfish, and sponges can promote wound healing, enhance blood circulation, and prevent infection. Additionally, it has anti-aging properties that have been demonstrated in mice with osteoporosis .
What is the best time to take the product?
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There are no clear recommendations as to the specific time of day when it should be taken. If you want to slow down the aging process and maintain adequate levels of this important protein in your body, you can take the supplement both in the morning and in the evening.
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