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Theaspirane CAS 36431-72-8
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Theaspirane CAS 36431-72-8

Theaspirane CAS 36431-72-8

Product Code: BM-2-3-134
CAS number: 36431-72-8
Molecular formula: C13H22O
Molecular weight: 194.31
EINECS number: 253-031-9
MDL No.: MFCD00085214
Hs code: 2932190090
Analysis items: HPLC>99.0%, LC-MS
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Changzhou Factory
Technology service: R&D Dept.-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of theaspirane cas 36431-72-8 in China. Welcome to wholesale bulk high quality theaspirane cas 36431-72-8 for sale here from our factory. Good service and reasonable price are available.

 

Theaspirane is a unique and fascinating compound derived from natural sources, particularly from marine organisms and certain plants. This organic molecule belongs to a class of compounds known for their diverse and often intriguing biological activities. Its name, derived from its structural characteristics and the sources of its discovery, hints at its potential as a therapeutic agent.

The unique structure features a combination of aromatic rings and spiro-fused rings, which contribute to its stability and bioactivity. This structural complexity allows it to interact with various biological targets, making it a subject of intense research in the fields of pharmacology and biotechnology.

One of the most promising aspects is its potential as an anticancer agent. Preliminary studies have shown that it can inhibit the proliferation of cancer cells by targeting specific signaling pathways involved in cell growth and division. Furthermore, which has also demonstrated antifungal and antibacterial properties, suggesting its potential use in the development of novel antimicrobial agents.

However, despite its promising biological activities, theaspirane is still in the early stages of research and development. Further studies are needed to fully understand its mechanism of action and to explore its potential therapeutic applications. Additionally, the isolation and purification from natural sources are challenging, which limits its availability for large-scale studies.

Produnct Introduction

Theaspirane CAS 36431-72-8 | Shaanxi BLOOM Tech Co., Ltd

Theaspirane CAS 36431-72-8 | Shaanxi BLOOM Tech Co., Ltd

Chemical Formula

C13H22O

Exact Mass

194.17

Molecular Weight

194.32

m/z

194.17 (100.0%), 195.17 (14.1%)

Elemental Analysis

C, 80.35; H, 11.41; O, 8.23

Applications | Shaanxi BLOOM Tech Co., Ltd

Theaspilane (CAS number 36431-72-8) is a high-end monomeric spice with a unique black tea aroma, sweetness, and fruity wood complex fragrance. Its chemical name is 2,6,10,10-tetramethyl-1-oxaspiro [4.5] dec-6ene. The spiro epoxides and double bonds in its molecular structure endow it with stable aroma properties, making it an important raw material for the food and fragrance industries.

Food Industry: Aroma Revolution from Traditional Beverages to New Products

Theaspirane tea beverages | Shaanxi BLOOM Tech Co., Ltd

Aroma enhancer for tea beverages

 

It is a natural aroma component in fermented teas such as black tea and black tea, and its aroma is highly compatible with the volatile compounds produced during the tea fermentation process. In the production of tea beverages, adding trace amounts of tea aroma spironolane can significantly enhance the aroma layering of the product

Aroma restoration: By simulating the caramel, woody, and floral aromas of black tea, it compensates for the loss of aroma caused by processing techniques in cold brewed or instant tea.

 

For example, adding 0.5-2ppm of tea aroma spirolane to cold brewed tea can make the tea soup present a richer aroma similar to that of hot brewed tea.
Flavor innovation: By compounding with spices such as limonene and linalool, innovative flavor tea drinks such as Earl Grey tea and peach oolong can be developed. A well-known tea beverage brand has successfully launched the "Thick Milk Latte" series of products with a long-lasting milk and tea aroma balance by adding tea aroma spirolane and γ - decanolactone.

Theaspirane tea | Shaanxi BLOOM Tech Co., Ltd
Theaspirane core | Shaanxi BLOOM Tech Co., Ltd

Core ingredients of fruit type essence

 

The fruit flavor characteristics make it a key raw material for fruit essence:

Berry essence: In strawberry, raspberry, blackcurrant and other essence, it can enhance the sweetness, acidity and authenticity of fruits. The experimental data showed that the aroma intensity of strawberry essence could be increased by 40% and the aroma retention time could be extended to 1.5 times of the traditional formula by adding 3ppm tea spiruline.

 

Citrus essence: Cooperating with citral and nerol, it can simulate the fresh aroma of citrus fruits such as grapefruit and grapefruit. Among the "Sunshine Grapefruit" essence developed by an international flavor company, the proportion of spiroolane reached 12%, which was successfully used in sports drinks and functional drinks.

Theaspirane fruit | Shaanxi BLOOM Tech Co., Ltd
Theaspirane bake | Shaanxi BLOOM Tech Co., Ltd

Flavor enhancers for dairy products and baked goods

 

Application of dairy products: In yogurt, cheese and other products, it can mask the sour and astringent taste produced by fermentation, while giving the product a light tea and cream aroma. A dairy company has increased the acceptance of its products by 25% by adding 0.8ppm camellian to Greek yogurt, which is particularly popular among young consumers.
Innovation in baked goods: By compounding with vanillin and maltol, unique flavored tea flavored bread, cakes, etc. can be developed. For example, adding 1ppm tea aroma spirolane to matcha cake can enhance the richness of matcha while reducing bitterness.

Aroma carrier of functional food

 

The antioxidant properties of tea scented spironolane give it dual value in functional foods:
Healthy drinks: In drinks containing functional ingredients such as tea polyphenols and catechins, not only can they improve taste, but they can also synergistically enhance product efficacy through their antioxidant effects. A study has shown that green tea extract drinks with added theaflavane have a 15% increase in DPPH free radical scavenging rate compared to the non added group.

Theaspirane food | Shaanxi BLOOM Tech Co., Ltd
Theaspirane tea aroma | Shaanxi BLOOM Tech Co., Ltd

 

Meal replacement products: In low calorie meal replacement powder, it can simulate the aroma of high calorie foods and enhance satiety. A certain brand has successfully developed a low calorie meal replacement stick with chocolate flavor by adding tea aroma spironole and ethyl maltol, which has received good market feedback.

Fragrance industry: aroma soul from daily chemical products to high-end perfume

Aroma balancing agent for tobacco products

 

The application of tea flavored spironolane in the tobacco industry has been over 30 years, and its core value lies in:
Traditional cigarettes: as the leading ingredient of essence of famous brands such as "555", it can simulate the slightly sweet fruit aroma of Virginia tobacco and cover up the odor of tobacco. Experiments have shown that adding 5-10ppm tea aroma spirolane to tobacco cigarettes can increase the softness of the smoke by 30% and the comfort of the aftertaste by 25%.
New type of tobacco: In heated non combustible (HNB) products, it can provide a lasting base note aroma and improve the sense of residual in the mouth. A certain electronic cigarette company has successfully developed a new type of cigarette cartridge with a refreshing tea aroma by adding tea scented spirolane and menthol, and its market share has rapidly increased to 18%.

Theaspirane tobacco | Shaanxi BLOOM Tech Co., Ltd

Aroma enhancer for personal care products

 

Theaspirane care | Shaanxi BLOOM Tech Co., Ltd

Perfume creation: woody and fruity characteristics make it a key raw material for oriental and exotic perfume. In a certain men's perfume, the perfumer created a unique fragrance with the artistic conception of "tea forest" by mixing tea spiruline with cedar and patchouli, and the annual sales volume after listing exceeded 500000 bottles.
Application of skin care products: In face cream, lotion and other products, it can provide elegant tea fragrance, and its antioxidant effect can help delay skin aging. A high-end skin care brand has increased the acceptance of product aroma by 40% and the repurchase rate of consumers by 25% by adding 0.2% tea spiruline to essence.

Innovative raw materials for home fragrances

 

Candles and rattan aromatherapy: When combined with raw materials such as coumarin and musk, home fragrance products with themes such as "tea fragrance study" and "Zen tea room" can be developed. A certain brand has successfully launched aromatherapy candles with Eastern aesthetic characteristics by adding tea scented spiroalkane and sandalwood, with annual sales of over 20 million yuan per product.
Car fragrance: Its stability in high temperature environments makes it an ideal raw material for car fragrances. An automobile supplies enterprise developed a vehicle mounted spray with fresh tea smell by mixing spiroolane and limonene. Market feedback shows that this product can effectively alleviate driving fatigue and improve driving safety.

Theaspirane materials | Shaanxi BLOOM Tech Co., Ltd

Iconic ingredients of high-end perfume

 

Theaspirane perfume | Shaanxi BLOOM Tech Co., Ltd

Because of its unique fragrance and scarcity, it has become one of the symbolic raw materials of high-end perfume:
**Niche perfume * *: among the minority perfume created by independent perfumers, it is often used to create a recognizable "fragrance signature". For example, in a certain perfume with the theme of "tea ceremony", the proportion of spiroolane is up to 15%, becoming a key bridge connecting the top note (bergamot) and base note (musk).
Limited edition perfume: Due to the complex synthetic process and high price, it is often used in limited edition or collection grade perfume. A luxury brand added spirosane and agarwood to the anniversary perfume, making the product price exceed 5000 yuan/bottle, and quickly sold out after listing.

product-340-68

Synthetic Process

Starting Material and Initial Reduction

  • The synthesis often starts with β-ionone as the raw material.
  • In the presence of aluminium chloride hexahydrate (AlCl3·6H2O), β-ionone undergoes sodium-ammonia reduction to form dihydro-β-ionol.

Bromination and Dehydrobromination

  • Dihydro-β-ionol is then brominated using cupric bromide.
  • Subsequently, dehydrobromination is carried out in the presence of calcium carbonate, resulting in a mixture of (E)-theaspirane and (Z)-theaspirane.

Purification

  • The resulting mixture isomers can be purified using chromatographic techniques such as column chromatography or preparative high-performance liquid chromatography (HPLC).
  • These methods help to separate the isomers and obtain pure product.

Other properties

Theaspirane, a remarkable and intriguing chemical entity, finds its natural origin embedded within the intricate world of fungi, specifically within the genus Aspergillus. This genus, comprising a vast array of species, is well-known for its prolific production of secondary metabolites, many of which exhibit potent biological activities. One such metabolite, is typically isolated from the fermentation broth of Aspergillus species grown under controlled laboratory conditions.

Theaspirane soil | Shaanxi BLOOM Tech Co., Ltd

 

These fungi, ubiquitous in nature, thrive in diverse environments such as soil, decaying organic matter, and even indoor settings. Their ability to convert simple nutrients into complex molecules with diverse chemical structures has garnered significant interest in the field of biotechnology and natural product chemistry. The isolation from Aspergillus fungi represents a significant milestone in harnessing the potential of fungal metabolites for medicinal and industrial applications.

 

During the fermentation process, Aspergillus species produce a myriad of compounds, among which stands out due to its unique structural features and promising bioactivity profiles. Researchers employ sophisticated analytical techniques to purify and characterize this compound, ensuring its identity and purity. The natural occurrence in Aspergillus fungi not only underscores the untapped potential of fungal biodiversity but also presents opportunities for the discovery of novel therapeutic agents and industrial catalysts.

Theaspirane features | Shaanxi BLOOM Tech Co., Ltd

As research into theaspirane and related fungal metabolites continues to expand, the natural sources of this compound are becoming increasingly important for advancing our understanding of fungal metabolism and its applications in various fields.

 

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