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1,3-Propane sultone is an organic compound, CAS 1120-71-4, The chemical formula is c3h6o3s, white powder. Slightly soluble in water, mainly used as a surfactant, and also used in the formulation of cosmetics and pharmaceutical industry as a pharmaceutical intermediate. It is also used in leather making, ink and dye synthesis as a sulfonating agent, widely used in industries such as pharmaceuticals, photosensitive materials, lithium batteries, biochemistry, textiles, lubrication, wastewater treatment, surface treatment, etc. Having the properties of general lactones. Heating together with potassium hydroxide produces potassium hydroxysulfonate. Highly reactive, capable of reacting with metal alcohols and phenols to introduce sulfonic acid groups. The reaction with amines does not require a catalyst. Heat to 130 ℃ in the presence of an alkaline catalyst with alcohols, phenols, amides, and active methylene compounds to introduce sulfonic acid groups. Furan derivatives are often produced by pressure distillation in the presence of zinc oxide or calcium chloride. Reacts with triethylamine to form a polymer.

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Chemical Formula |
C3H6O3S |
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Exact Mass |
112 |
|
Molecular Weight |
112 |
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m/z |
122 (100.0%), 124 (4.5%), 123 (3.2%) |
|
Elemental Analysis |
C, 29.50; H, 4.95; O, 39.30; S, 26.25 |
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A method for preparing 1,3-Propane sultone acid lactone comprises the following steps:
①
After mixing 1,3-dihalopropane with sulfonating agent and solvent, the sulfonation reaction was carried out at a certain temperature to obtain sodium 1-halo-3-propane sulfonate;
②
Add the obtained sodium 1-halo-3-propane sulfonic acid into water, add strong acid to adjust pH = 13 for acidification, concentrate, filter and remove inorganic salts, and then concentrate to dryness to obtain 1-halo-3-propane sulfonic acid;
③
1,3 propane sulfonic acid lactone was prepared by heating the obtained 1-halo-3-propane sulfonic acid under vacuum and lactonization.
It has the following advantages:
The raw material 1,3 dihalopropane used in the method of the present invention is less toxic, safer, more easily available and recyclable for continuous application, and also convenient for storage, greatly reducing raw materials and operating costs;
The method of the present invention has less output of three wastes, reduces environmental pollution, and the purity of the prepared product is high, up to more than 99%; The water content of the product is less than 0.1%.


1,3-Propane sultone (1,3-PS) is an organic compound with the chemical formula C3H6O3S, belonging to functional fine chemical new materials.
Surfactant:
Due to its unique chemical structure, it can be used as a surfactant. Surfactants have the ability to reduce the surface tension of liquids, thus playing an important role in various industrial applications. For example, it can provide excellent performance in detergent, emulsifier, foam stabilizer, etc.
pharmaceutical intermediates:
In the pharmaceutical industry, it is used as a pharmaceutical intermediate. It can participate in the synthesis of various drugs and provide key raw materials for drug preparation. This gives it an irreplaceable position in the pharmaceutical and chemical industry.
Cosmetics preparation:
Due to its excellent performance, it is also widely used in the formulation of cosmetics. In cosmetics, it can be used as an emulsifier, stabilizer, or thickener to help improve the stability and effectiveness of cosmetics.
Synthesis of sulfonating agents for leather, ink, and sensitizing dyes:
In the leather industry, it can be used as a sulfonating agent for the tanning and finishing process of leather. It can improve the softness, glossiness, and durability of leather. At the same time, it can also be used as a sulfonating agent in the synthesis of ink and sensitizing dyes to improve their performance.
Lithium battery electrolyte additive:
The high-purity substance can be used as an additive for lithium battery electrolytes. It can improve the cycling performance and service life of batteries, enhance their safety and stability.
This is of great significance for promoting the development of lithium battery technology.

Application in the field of pharmaceuticals and chemical engineering:
Synthetic drugs: can be used as key raw materials for synthesizing multiple drugs. For example, it can participate in the synthesis of drugs with antibacterial, anti-inflammatory, anti-tumor and other activities. The development and application of these drugs are of great significance for improving human health.
Drug intermediates: In the process of drug synthesis, they can act as intermediates to participate in the synthesis of drug molecules with specific pharmacological effects. This helps simplify the drug synthesis process, improve drug yield and purity.
Application in the field of photosensitive materials:
Photosensitizer synthesis: It can be used as a raw material for the synthesis of photoreceptors, and is used to prepare photosensitive materials with excellent photosensitive properties. These photosensitive materials have a wide range of applications in fields such as photography, printing, and electronics.
Improving photosensitive performance: By introducing this substance, the photosensitive performance and stability of photosensitive materials can be improved, and their service life and reliability can be enhanced.
Application in the field of lithium batteries:
Electrolyte additives: High purity additives can be used as electrolytes for lithium batteries to improve the cycling performance and service life of the battery. It can improve the charging and discharging efficiency of the battery, reduce the internal resistance of the battery, thereby increasing the energy density and power density of the battery.
Enhancing battery safety: By adding, the thermal and chemical stability of lithium batteries can be improved, reducing the risk of thermal runaway during charging and discharging, thereby improving battery safety.
Application in the field of biochemistry:
Synthesis of bioactive substances: can serve as a key raw material for synthesizing bioactive substances and participate in the synthesis of compounds with specific biological activities. These compounds have wide applications in fields such as medicine, pesticides, and food additives.
Improving bioavailability: By introducing this substance, the solubility and stability of bioactive substances can be improved, enhancing their bioavailability and efficacy.
Application in the textile field
Textile processing agent: can be used as a raw material for textile processing agents to improve the performance of textiles. For example, it can improve the softness, glossiness, and anti-static performance of textiles.
Dye synthesis: In dye synthesis, it can be used as a sulfonating agent to participate in the synthesis of dyes with excellent dyeing properties. These dyes have a wide range of applications in the textile printing and dyeing industry.
Application in lubrication field
Lubricant additive: can be used as a raw material for lubricant additives to improve the performance of lubricants. For example, it can improve the extreme pressure anti-wear performance, antioxidant performance, and clean dispersion performance of lubricating oil.
Improving friction performance: By adding its substance, the friction performance between friction pairs can be improved, reducing the friction coefficient and wear, thereby increasing the service life and reliability of mechanical equipment.
Application in the field of wastewater treatment
Wastewater treatment agent: can be used as a raw material for wastewater treatment agents to treat wastewater containing harmful substances such as heavy metal ions and organic pollutants. It can undergo chemical reactions with these harmful substances, converting them into harmless or low toxic substances, thereby reducing the pollution level of wastewater.
Improving treatment efficiency: By introducing 1,3-Propane sultone, the efficiency and effectiveness of wastewater treatment can be enhanced. It can accelerate the conversion rate and removal rate of harmful substances, thereby reducing the cost and treatment time of wastewater treatment.
Application in the field of surface treatment
Metal surface treatment agent: can be used as a raw material for metal surface treatment agents to improve the properties of metal surfaces. For example, it can improve the corrosion resistance, wear resistance, and adhesion of metal surfaces.
Improving coating quality: By introducing this substance during the preparation process of metal coatings, the uniformity, density, and adhesion properties of the coating can be improved, thereby enhancing the quality and service life of the coating.
Application in the field of electroplating
Synthesis of electroplating intermediates: It is the starting material for synthesizing various electroplating intermediates. For example, it can participate in the synthesis of PPS, UPS, DPS and other electroplating intermediates, which have wide applications in the electroplating industry.
Improving electroplating quality: By introducing this substance, the uniformity, density, and adhesion of the electroplating layer can be improved, thereby enhancing the quality and corrosion resistance of the electroplating layer.
Application of antibacterial enhancers
Enhanced antibacterial effect: It can be used as an antibacterial enhancer and combined with sulfonamide drugs to enhance its antibacterial effect. This is of great significance for the treatment of diseases such as avian coccidiosis and intestinal bacterial infections.
Expanding antibacterial spectrum: By introducing this substance, the antibacterial spectrum of sulfonamide drugs can be expanded, making them have inhibitory effects on more types of bacteria.
Applications in other fields
Brightening agent synthesis: In the synthesis of brightening agents, it can be used as one of the raw materials to participate in the synthesis of brightening agents with excellent brightening properties. These brighteners have a wide range of applications in fields such as metal processing and surface treatment.
Synthesis of Gemini Surfactants: It can also be used as one of the raw materials for synthesizing Gemini Surfactants. Gemini surfactants have excellent surface activity and emulsifying properties, and are widely used in detergents, cosmetics, and other fields.
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