Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 1-acetyl-2-phenylhydrazine cas 114-83-0 in China. Welcome to wholesale bulk high quality 1-acetyl-2-phenylhydrazine cas 114-83-0 for sale here from our factory. Good service and reasonable price are available.
1-Acetyl-2-Phenylhydrazine (APH) is a white solid, odorless, soluble in hot water and ethanol, but insoluble in ether cold water. It is an important stabilizer for fine organic chemical intermediates and is widely used in medicine, pesticide, chemical industry, and other fields. Store in a cool and ventilated warehouse. Keep away from kindling and heat sources. It should be stored separately from oxidants and avoid mixed storage. Provide corresponding varieties and quantities of fire-fighting equipment. The storage area shall be equipped with leakage emergency treatment equipment and appropriate receiving materials.
APH Applications: APH is used in the manufacture of anaerobic adhesives. A wide range of products has been developed for use with APH. These products include gaskets, sealants, adhesives, and retaining compounds. Research and development in the field of anaerobic adhesives are growing with APH.
Packaging: 15 Gallon fiber drum UN rated 1G/Y/106/S fiber drum with steel top and fiber bottom. 25 Kg, net.
Storage and handling guidelines: Keep container tightly closed in a dry and well-ventilated place, store below 110 deg. F. Shelf-life: 2 years.
Synthetic APH: m-phthaloyl chloride is condensed with diethyl malonate insolvent under the condition of low temperature and strong base 2. Take the condensation product obtained in step 1, add water and acid, adjust the pH value, heat and reflux for deacidification, and complete the synthesis of APH through extraction and distillation The product synthesized by the invention can be applied to metal, organic and polymer materials, dyes, pesticides, medicine, and other fields.
We are the supplier of 1-Acetyl-2-Phenylhydrazine.
Remark: BLOOM TECH(Since 2008), ACHIEVE CHEM-TECH is the subsidiary of us.
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Melting point |
128 – 131 °C ( lit. ) |
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Boiling point |
271.72 °C ( rough estimate ) |
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Density |
1.1392 ( rough estimate ) |
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Storage conditions |
Store at + 15 ° C to + 25 ° C. |
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Specific rotation |
- 46 º (C = 0.5, HCl) |
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Acidity coefficient ( pKa ) |
12.75 ± 0.23 ( Predicted ) |
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Refractive index |
1.5250 (estimated) |
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WGK Germany |
3 |
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RTECS No. |
lq9450000 |
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Safety instructions |
22-26-36-24 / 25-36 / 37 |
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Prevention instructions |
P264 - P270 - P301 + P310 + P330 - P405 - P501 - P261 - P280a-P301 + P310a-P305 + P351 + P338 - P501a |
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RTECS |
AJ2900000 |
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TSCA |
Yes |
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HazardClas |
6.1 |
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Packing Group |
II |
1-acetyl-2-phenylhydrazine (CAS number: 114-83-0), as an important fine organic chemical intermediate, not only has wide industrial application value, but also exhibits unique efficacy in the field of sterilization. Its bactericidal effect and related applications are of great significance for ensuring safety and hygiene in multiple fields such as public health, agricultural production, and food processing.
Sterilization mechanism
The bactericidal effect is mainly based on its chemical structure and biological activity. As an organic compound, it can destroy the cellular structure of bacteria through various pathways, inhibit their growth and reproduction, and thus achieve the purpose of sterilization.
Can interact with phospholipid molecules on bacterial cell membranes, disrupting the integrity and stability of the cell membrane. The cell membrane is an important barrier for bacterial cells. Once damaged, the substances inside the bacteria will leak out, leading to bacterial death.
It can also inhibit bacterial metabolic processes, especially affecting bacterial energy metabolism and DNA replication.
By interfering with these critical life processes, bacterial growth and reproduction can be inhibited, further reducing the number of bacteria. Under specific conditions, free radicals can be generated, which have strong oxidizing properties and can attack various biomolecules inside bacterial cells, such as proteins, nucleic acids, etc., leading to the destruction of bacterial cell structure and function.
Application in the field of sterilization
The bactericidal effect makes it widely applicable in multiple fields. The following is a detailed exploration of its application areas:
In the field of healthcare, it can be used as a disinfectant. Its potent bactericidal effect can quickly kill various microorganisms such as bacteria, viruses, and fungi, effectively preventing and controlling cross infection. In addition, it can also be used for disinfection and sterilization of medical devices to ensure their hygiene and safety.
Hand disinfection: It can be made into hand disinfectant for medical staff and patients to disinfect their hands. By spraying or applying hand sanitizer, microorganisms on the surface of the hands can be quickly killed, reducing the risk of cross infection.
Medical device disinfection: It can also play an important role in the disinfection and sterilization process of medical devices. It can be used to sterilize medical devices by soaking, wiping or spray to ensure the health and safety of medical devices.
In the field of agricultural production, it can be used as a pesticide to prevent and control crop diseases and pests. Its broad-spectrum bactericidal effect can quickly kill various pathogens and pests, protecting crops from damage caused by pests and diseases.
Disease prevention and control: It can be used to prevent and control various diseases of crops, such as leaf spot disease, rust disease, powdery mildew, etc. By spraying pesticide formulations containing 1-acetyl-2-phenylhydrazine, pathogenic bacteria can be quickly killed, and the spread and spread of diseases can be controlled.
Pest control: In addition to its bactericidal effect, it can also have a certain toxic effect on certain pests. By spraying pesticide formulations containing this substance, pests can be killed or driven away, protecting crops from pest damage.
In the field of food processing, it can be used as a food preservative. Its potent bactericidal effect can extend the shelf life of food and prevent food from spoiling and spoiling.
Extended shelf life: By adding an appropriate amount of this substance to food, it can inhibit the growth and reproduction of microorganisms in the food, extending the shelf life of the food. This is particularly important for foods that require long-term preservation, such as canned goods, meat products, etc.
Preventing spoilage: It can also prevent food from spoiling and maintain its taste and nutritional value. By inhibiting the growth and reproduction of microorganisms, the production of spoilage substances in food can be reduced, maintaining the original flavor and taste of the food.
In the field of water treatment, it can be used as a fungicide to treat microbial contamination in various water sources.
Drinking water treatment: During the process of drinking water treatment, bacteria, viruses, and other microorganisms in the water can be killed to ensure the hygiene and safety of drinking water. By adding an appropriate amount of this substance to drinking water, it can quickly kill microorganisms in the water and improve the quality of drinking water.
Industrial water treatment: It can also play an important role in the process of industrial water treatment. It can be used for sterilization treatment of industrial water systems such as cooling water and circulating water, preventing the growth and reproduction of microorganisms from causing corrosion and blockage of equipment.
In addition to the aforementioned fields, it can also exert bactericidal effects in other areas. For example, in animal husbandry, it can be used as a feed additive to prevent and treat infectious diseases of animals; In the field of public health, it can be used for disinfection and sterilization in public places such as hospitals, schools, restaurants, etc; In the laboratory, it can be used for disinfection of experimental equipment and environment.
1-Acetyl-2-phenylhydrazine is a versatile compound with significant applications in organic synthesis and pharmaceutical research. Its unique structure and chemical properties make it a valuable building block in the synthesis of various bioactive molecules, including anti-cancer agents and other pharmaceuticals. While the compound offers numerous benefits, it is essential to handle it with care due to its potential health hazards. By adopting sustainable manufacturing processes and exploring new applications, the scientific community can ensure the long-term availability and utility of 1-Acetyl-2-phenylhydrazine. As research continues to advance, this compound is poised to play an even more prominent role in shaping the future of chemistry and medicine.
Sterilization effect evaluation
To evaluate the bactericidal effect, a series of experiments and tests are required. The following is a brief introduction to the evaluation method of its bactericidal effect:
Through microbial cultivation experiments, the bactericidal effect of 1-acetyl-2-phenylhydrazine on specific microorganisms can be evaluated. Mix the solution containing the substance with the microbial sample and culture it under certain conditions to observe the growth of the microorganisms. By comparing the changes in microbial count between the treatment group and the control group, the bactericidal effect can be evaluated.
The determination of sterilization rate is one of the important indicators for evaluating its sterilization effect. By measuring the changes in microbial count before and after treatment, the sterilization rate can be calculated. The higher the sterilization rate, the better the sterilization effect.
When used as a fungicide, toxicity assessment is also necessary. By measuring its toxic reactions to humans or animals, its safety and applicability can be evaluated. The results of toxicity assessment are of great significance for determining its dosage and scope of use.
Future Prospects
Looking ahead, the use of 1-Acetyl-2-phenylhydrazine is expected to continue growing, driven by advances in pharmaceuticals and organic synthesis. As researchers uncover new applications for the compound, its demand in various industries is likely to increase. Trends such as the development of high-purity compounds and sustainable manufacturing processes will shape the future of 1-Acetyl-2-phenylhydrazine production and use.
In addition to its traditional applications, 1-Acetyl-2-phenylhydrazine may find new uses in emerging fields such as nanotechnology and materials science. Its unique chemical properties and reactivity profile make it a candidate for the synthesis of novel nanomaterials and functional polymers. As research in these areas progresses, new applications for 1-Acetyl-2-phenylhydrazine may emerge, further expanding its utility.
Frequently Asked Questions
What happens when acetaldehyde reacts with phenylhydrazine?
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So, when acetaldehyde is treated with phenylhydrazine, the Nitrogen atom of the phenylhydrazene serves as a nucleophile and attacks the electrophilic carbon of the acetaldehyde and removes water to give acetaldehyde phenylhydrazone.
What is phenyl hydrazine hydrochloride used for?
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Phenylhydrazine hydrochloride (PHZ) is a chemical compound. PHZ and its derivatives were used firstly as antipyretics, treatment of blood disorders such as polycythaemia Vera. For many years phenyl hydrazine was used for experimental induction of anaemia in animal models.
What is acetyl phenylhydrazine used for?
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1-Acetyl-2-phenylhydrazine (APH) is used in the manufacture of anaerobic adhesives. A wide range of products have been developed for use with 1-Acetyl-2-phenylhydrazine (APH). These products include gaskets, sealants, adhesives, and retaining compounds.
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