What is the boiling point of Iodomethane - d3?

Iodomethane-d3, also known as deuterated iodomethane, is a deuterium-labeled compound with significant applications in various scientific fields, especially in nuclear magnetic resonance (NMR) spectroscopy. As a reliable supplier of Iodomethane-d3, we often receive in-depth inquiries from our clients, one of the frequently asked questions being about its boiling point. In this blog, we will delve into the boiling point of Iodomethane-d3, its influencing factors, and its implications in practical applications.

Iodomethane-d3

Product Code: BM-2-5-135
Researched by: BLOOM TECH
En Name: Iodomethane-d3
CAS No.: 865-50-9
MF: cd3i
MW: 144.96
EINECS No.: 212-744-5
Enterprise standard: HPLC>99.0%, HNMR
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Xi'an Factory
Technology service: R&D Dept.-1

Iodomethane-d3 is a deuterated form of iodomethane (CH₃I). Deuteration involves replacing one or more hydrogen atoms with deuterium, a stable isotope of hydrogen. The chemical formula of Iodomethane-d3 is CD₃I. The replacement of hydrogen with deuterium changes some physical and chemical properties of the molecule compared to the non-deuterated iodomethane, although in many cases, the differences are relatively subtle.

The boiling point of a substance is a crucial physical property that reflects the intermolecular forces within the substance. For Iodomethane-d3, its boiling point is approximately 42 °C. This value is close to that of non-deuterated iodomethane, whose boiling point is around 42.5 °C.

The reason for the similarity in boiling points is that the intermolecular forces that primarily determine the boiling point, such as London dispersion forces and dipole-dipole interactions, are not significantly affected by the replacement of hydrogen with deuterium. London dispersion forces arise from temporary dipoles induced in molecules due to the motion of electrons. Since the electron cloud distribution in CD₃I and CH₃I is quite similar, the strength of London dispersion forces is comparable. Dipole-dipole interactions also remain relatively unchanged because the overall molecular polarity is mainly determined by the electronegativity difference between iodine and carbon, and deuterium substitution does not alter this significantly.

Although the boiling points of Iodomethane-d3 and non-deuterated iodomethane are similar, there are still some factors that can cause minor variations in the boiling point of Iodomethane-d3:

Purity

The presence of impurities in Iodomethane-d3 can affect its boiling point. Impurities can disrupt the intermolecular forces, either by strengthening or weakening them, depending on their nature. For example, if there are polar impurities in the sample, they can increase the overall dipole-dipole interactions, leading to a slightly higher boiling point. On the other hand, non-polar impurities may weaken the intermolecular forces and cause a lower boiling point. As a supplier, we ensure that our Iodomethane-d3 products have high purity levels to minimize such effects.

External Pressure

The boiling point of a liquid is also affected by the external pressure. According to the Clausius-Clapeyron equation, the boiling point decreases as the external pressure decreases. At standard atmospheric pressure (1 atm or 101.325 kPa), the boiling point of Iodomethane-d3 is around 42 °C. However, if the experiment is conducted at a lower pressure, such as in a vacuum distillation setup, the boiling point will be lower.

The boiling point of Iodomethane-d3 plays a crucial role in its applications:

NMR Spectroscopy

In NMR spectroscopy, Iodomethane-d3 is often used as a solvent or a reference compound. The relatively low boiling point allows for easy evaporation and removal from the sample after the NMR experiment. This is particularly important in cases where the sample needs to be recovered or further analyzed.

Chemical Synthesis

In chemical synthesis, the boiling point is considered when designing reaction conditions. For reactions that involve Iodomethane-d3, the boiling point helps determine the appropriate temperature range for reflux or distillation processes. For example, if a reaction requires the use of Iodomethane-d3 as a reactant and a reflux setup is used, the temperature should be maintained above its boiling point to ensure continuous reaction and prevent the loss of the reactant.

As a leading supplier of Iodomethane-d3, we are committed to providing high-quality products. Our Iodomethane-d3 is produced with strict quality control measures to ensure high purity and consistent boiling points. We understand that different customers may have different requirements for the product, and we can offer customized solutions according to their specific needs.

In addition to Iodomethane-d3, we also supply a wide range of other chemical products, such as Polymyxin B Sulfate Powder CAS 1405-20-5, Rhein CAS 478-43-3, and Scopolamine Hydrobromide Powder CAS 114-49-8. These products are also of high quality and are widely used in various research and industrial applications.

If you are interested in our Iodomethane-d3 or other chemical products, we welcome you to contact us for procurement discussions. Our professional sales team will provide you with detailed product information, competitive prices, and excellent after-sales service. We look forward to establishing long-term and stable cooperative relationships with you.

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2. Carey, F. A., & Sundberg, R. J. (2017). Advanced Organic Chemistry: Part A: Structure and Mechanisms. Springer.
3.