The chemical formula of IODOMETHANE-D3(Link: https://www.bloomtechz.com/synthetic-chemical/api-researching-only/organic-intermediate.html) is CD3I, CAS 865-50-9, where D represents deuterium isotope (the relative atomic mass of deuterium is 2). According to the weighted average of isotope mass, the relative molecular mass is about 131.92 g/mol. It is a colorless to pale yellow liquid. It is in liquid state at normal temperature and has a special smell. The density is about 2.616 g/cm³. This means it is heavier than water and therefore will sink in water. The refractive index is 1.5432 (20°C, yellow light wavelength). The refractive index refers to the degree of deflection of light when propagating in a material, and the specific value can be used to determine the optical properties of the sample. It is an organic solvent and can be dissolved in various organic solvents. It has good solubility in common organic solvents such as ethanol, acetone, esters and aromatic hydrocarbons, but relatively low solubility in water. It is an important marker for nuclear reaction research. It can be used to study nuclear physical phenomena such as nuclear reaction rate, cross section, and spontaneous fission. It can also be used as an intermediate in organic synthesis reactions. By introducing IODOMETHANE-D3 during the synthesis, the selectivity of specific reaction pathways can be achieved and lead to the formation of specific compounds. This method is widely used in pharmaceutical synthesis, fine chemical manufacturing, and organic synthesis research.
The application of IODOMETHANE-D3 in the laboratory and in daily life is as follows:
1. Labeling reagent:
IODOMETHANE-D3 is widely used as a deuterium (D) labeling reagent. Due to its presence of deuterium isotopes, IODOMETHANE-D3-labeled compounds can be more easily detected and identified by techniques such as mass spectrometry compared to the naturally abundant hydrogen isotopes (relative abundance of deuterium isotopes is 0.0156%). This labeling method can be used to study the metabolic pathways of compounds, reaction mechanisms, and analyze the presence and concentration of specific compounds in samples.
2. Nuclear magnetic resonance (NMR) reference material:
Because IODOMETHANE-D3 has a clear signal in the NMR spectrum, it is often used as a reference standard substance for deuterium spectrum (2H NMR). Its characteristic chemical shift signals can be used to correct sample solvents and analyze and identify NMR spectra of other compounds. In addition, IODOMETHANE-D3 can also be used as a fixed marker to monitor the position and movement of compounds.
3. Reagents:
IODOMETHANE-D3 can be used as a reagent in organic synthesis. It can react with alkali metals, boron alcohols, haloalkanes, etc. to generate compounds with Deuterium (deuterium) labels. These labeled compounds can be used to study reaction mechanisms, track reaction paths, and analyze and characterize the properties of compounds. Deuterium-labeled compounds are widely used in the research field to track material transformation, solubility studies, nucleosynthesis reactions, etc.
4. Solvent:
Due to its inertness and relatively low polarity, IODOMETHANE-D3 is widely used as an inert solvent. It provides a highly inert solvent environment with weak interactions with certain chemical reagents in many experiments. Due to its moderate solubility and stability, IODOMETHANE-D3 is often used in nuclear magnetic resonance (NMR) experiments, mass spectrometry, drug discovery research and other occasions that require inert solvents.
5. Reaction intermediates:
IODOMETHANE-D3 can also be used as an intermediate in organic synthesis reactions. By introducing IODOMETHANE-D3 during the synthesis, the selectivity of specific reaction pathways can be achieved and lead to the formation of specific compounds. This method is widely used in pharmaceutical synthesis, fine chemical manufacturing, and organic synthesis research.
6. Deuterium exchange reagent:
IODOMETHANE-D3 can be used as a deuterium exchange reagent for introducing deuterium (D) into compounds containing metal-hydrogen bonds or carbon-hydrogen bonds. Deuterium exchange reagents are commonly used to study the mechanism and kinetics of catalysts, metal complexes, and hydrogen bond-related reactions.
7. To study nuclear reactions:
The isotope deuterium (D) of IODOMETHANE-D3 is an important labeling agent for nuclear reaction research. It can be used to study nuclear physical phenomena such as nuclear reaction rate, cross section, and spontaneous fission.
8. Methane source: IODOMETHANE-D3 can be used as a source of methane. Under certain laboratory conditions, IODOMETHANE-D3 can generate methane (CH4) by reacting with reducing agents such as sodium borohydride. This method can be used to prepare deuterium (D) or tritium (T) labeled methane for research or other experimental needs.
In addition to the above-mentioned uses, IODOMETHANE-D3 also plays an important role in other fields. These include materials science, environmental science, biochemistry, pharmacy and other fields.