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Phenibut Capsules
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Phenibut Capsules

Phenibut Capsules

1.General Specification(in stock)
(1)API(Pure powder)
(2)Capsules
2.Customization:
We will negotiate individually, OEM/ODM, No brand, for secience researching only.
Internal Code: BM-6-009
Phenibut CAS 1078-21-3
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Xi’an Factory
Analysis: HPLC, LC-MS, HNMR
Technology support: R&D Dept.-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of phenibut capsules in China. Welcome to wholesale bulk high quality phenibut capsules for sale here from our factory. Good service and reasonable price are available.

 

Phenibut Capsules are a dietary supplement or pharmaceutical preparation primarily composed of Phenibut (β - phenyl - γ - aminobutyric acid).

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

Phenibut is an artificially synthesized central nervous system inhibitor with a chemical structure similar to the neurotransmitter gamma aminobutyric acid (GABA). It can pass through the blood-brain barrier and act on GABA receptors in the brain, producing sedative, anti anxiety, and sleep improving effects. It is used to relieve anxiety, tension, and stress, help people with difficulty falling asleep or poor sleep quality, improve mood swings, and enhance psychological states. Some studies suggest that Phenibut may have a positive impact on attention and memory.

 

At the same time, our company not only provides capsules, but also powders and injections. If needed, please feel free to contact us at any time.

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

 

Product Introduction

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

 

Phenibut COA

Phenibut Capsules | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules COA | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules COA | Shaanxi BLOOM Tech Co., Ltd

Phenibut Capsules COA | Shaanxi BLOOM Tech Co., Ltd

Applications

The main use of Phenibut Capsules revolves around the pharmacological properties of its core component Phenibut (β - phenyl - γ - aminobutyric acid). As an artificially synthesized central nervous system inhibitor, Phenibut simulates the mechanism of action of the neurotransmitter gamma aminobutyric acid (GABA) and is clinically used to regulate neural activity, alleviate anxiety, improve sleep quality, and assist in the treatment of certain neurological disorders. The following provides a detailed analysis of its purpose from multiple dimensions:

Adjuvant treatment for neurological disorders
 

Phenibut is used as an adjuvant medication in the treatment of certain neurological disorders, particularly those associated with anxiety, insomnia, or increased neural excitability. Some doctors use Phenibut as an adjuvant therapy for PTSD, especially for patients with anxiety and sleep disorders. Its sedative and anti anxiety effects may help alleviate symptoms. Some studies suggest that Phenibut may improve language fluency in stuttering patients by reducing excessive excitation of the nervous system. But this use has not yet been widely recognized. Phenibut's GABAergic effects may help alleviate anxiety and tremors during alcohol withdrawal, but should be used under the guidance of a doctor.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

Applications in the field of sports and fitness

 

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

Although Phenibut is not designed for exercise purposes, it has received some attention in the fitness community, mainly due to its relaxing and anti anxiety effects that may help alleviate pre exercise tension. Some fitness enthusiasts have reported that Phenibut can help them relax their muscles and reduce anxiety, resulting in better performance during training. However, it should be noted that this usage lacks scientific basis and may mask potential risks of sports injuries. The sedative effect of Phenibut may help alleviate nerve fatigue after high-intensity training, but long-term use may interfere with natural sleep and recovery mechanisms.

Other potential uses
 

Phenibut has also been explored for use in other fields, but these uses often lack sufficient clinical evidence support and are highly controversial. Some users have reported that Phenibut can alleviate migraine symptoms, possibly indirectly through its sedative and anti anxiety effects. But this use has not yet been widely recognized by the medical community. Due to the anti anxiety effect of Phenibut, some patients with social anxiety disorder have attempted to use it to alleviate symptoms. However, long-term use may lead to dependency and cannot replace professional psychotherapy.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

Manufacturing Information

The production of Phenibut Capsules involves multiple stages, including raw material selection, formula design, production process, quality control, etc. The following provides a detailed analysis of its production information from multiple dimensions:

1

Raw material selection and quality control

The core raw material of Phenibut Capsules is Phenibut (chemical name: 4-amino-3-phenylbutyric acid hydrochloride), and its purity and quality directly affect the safety and effectiveness of the final product.

 
 

Raw material purity

The purity of Phenibut needs to reach over 98% to ensure that the impurity content is within a safe range. Impurities may include unreacted raw materials, by-products, or degradation products, which may cause toxicity or side effects to the human body.

 
 
 

Supplier Qualification

Raw material suppliers must have GMP (Good Manufacturing Practice) certification and provide complete raw material quality documents, including COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), etc.

 
 
 

Raw material storage

Phenibut should be stored in a dry, cool, and dark environment to prevent degradation or deterioration. The storage temperature is usually controlled between 2-8 ℃, and the humidity does not exceed 50%.

 
2

Formula design

The formula design of Phenibut needs to consider the stability, bioavailability, and patient compliance of the drug. Common excipients include fillers, disintegrants, lubricants, and coating materials.

 

Filler

Used to increase the volume of capsule contents, ensuring uniform drug content in each capsule. Common fillers include microcrystalline cellulose, lactose, and starch.

 
 

Disinfectant

Promotes rapid disintegration of capsules in the gastrointestinal tract, releasing drugs. Common disintegrants include carboxymethyl starch sodium and cross-linked carboxymethyl cellulose sodium.

 
 

Lubricant

Reduce friction between particles and molds to ensure smooth capsule filling process. Common lubricants include magnesium stearate and talc powder.

 
 

Coating material

Can be used to mask the unpleasant odor of drugs or improve drug stability. Common coating materials include hydroxypropyl methylcellulose and polyethylene glycol.

 
3

Production process

The production process of Phenibut Capsules must strictly follow GMP standards to ensure product quality and consistency.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

1

 

Raw material pretreatment

Crushing and sieving: Grind Phenibut raw materials to an appropriate particle size (usually 20-100 mesh) and ensure uniform particle size through sieving.
Mixing: Mix Phenibut with excipients according to the formula ratio, and use equipment such as a 3D mixer to ensure uniform mixing. The mixing time is usually 10-30 minutes, and the speed is 10-30 rpm.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

2

 

Granulation

Wet granulation: Mix the mixed powder with a binder (such as polyvinylpyrrolidone solution) to make wet granules. The concentration and amount of adhesive need to be adjusted according to the properties of the raw materials.
Drying: Place the wet particles in a fluidized bed dryer and dry them at 40-60 ℃ until the moisture content is below 3%.
Granulation: Pass the dried particles through a granulator to ensure uniform particle size.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

3

 

Capsule filling

Filling: Fill the whole granule into the capsule shell. The filling amount needs to be adjusted according to the drug content and capsule specifications of each capsule.
Polishing: Polish the filled capsules to remove surface powder and improve appearance quality.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

4

 

Coating (optional)

Preparation of coating solution: Dissolve the coating material in an appropriate solvent to prepare the coating solution.
Coating: Place the capsule in a coating pot, spray coating solution to form a uniform coating layer. The coating temperature is usually between 30-50 ℃.

Phenibut Capsules use | Shaanxi BLOOM Tech Co., Ltd

5

 

package

Inner packaging: Place the capsule into a plastic bottle or aluminum-plastic blister to ensure sealing.
Outer packaging: Label with product name, specifications, production date, expiration date, and other information.

4

Quality control

Phenibut's quality control runs through the entire production process, including raw material inspection, intermediate product inspection, and finished product inspection.

Raw material inspection

Check the color, shape, and odor of the raw materials to ensure there are no abnormalities. Use HPLC (high-performance liquid chromatography) method to determine the purity of Phenibut, ensuring that it is ≥ 98%. Detect impurities such as heavy metals and solvent residues in raw materials to ensure compliance with pharmacopoeia standards.

Intermediate product inspection

Check the particle size distribution of the particles to ensure they meet the process requirements. Take samples from different batches or different locations within the same batch to determine the content of Phenibut and ensure its uniformity.

Finished product inspection

Check the shape, color, and surface finish of the capsule to ensure there are no defects. Randomly select a certain number of capsules and measure their filling amount to ensure that the difference in filling amount is within ± 5%. Use a disintegrator to measure the disintegration time of the capsule, ensuring complete disintegration within 15 minutes. Use HPLC method to determine the content of Phenibut in the finished product, ensuring that it meets 90% -110% of the labeled amount. Detect the quantity of bacteria, mold, and yeast in the finished product to ensure compliance with pharmacopoeia standards.

5

Challenges and Solutions in Production

During the production process of Phenibut, the following challenges may be encountered:

1

Raw material stability

Phenibut is prone to moisture and oxidation, leading to a decrease in purity. Moisture resistant packaging should be used, and temperature and humidity should be controlled during storage.

2

Content uniformity

Uneven mixing of particles may result in inconsistent drug content per capsule. We should optimize the mixing process, extend the mixing time, and use a three-dimensional mixer to improve the mixing effect.

3

Disintegration time limit

Insufficient dosage of disintegrant or excessive coating may result in prolonged capsule disintegration time. The dosage of disintegrants and coating process should be adjusted to ensure that the capsules disintegrate within the specified time.

4

Microbial contamination

Production environment or raw material pollution may lead to excessive microbial content in finished products. We should strengthen the cleaning and disinfection of the production environment, and conduct microbiological testing on raw materials.

 

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