Bovine Bone Collagen

1. Skeletal system:
This is the biggest difference between bovine bone collagen peptide and flaxseed oligopeptide. Flaxseed peptide has almost no direct effect on bones, while peptone can be called "Rocket" in the field of bones.
① Preventing Osteoporosis - Preventing Calcium Loss
Collagen peptides derived from cow bones contain naturally bound hydroxyapatite and calcium ions, and their bioavailability far exceeds that of ordinary calcium supplements. The special triple helix structure can guide the orderly deposition of calcium salts on bone trabeculae, increasing bone density. The academic paper "Research on the preventive effect of peptone on osteoporosis" experimentally proves that peptone has a preventive effect on osteoporosis in ovariectomized rats.

Postmenopausal women who supplement with 10 grams of collgen peptides daily can increase their bone calcium content by 7% after 6 months.

② Promoting osteoblast proliferation - true "bone making"
MTT assay showed that 0.3mg/ml recombinant human micro-molecule collgen can significantly promote the proliferation of human osteoblasts (HOBs) and increase the percentage of G2+S phase cells. It can effectively improve the imbalance between osteoblasts and osteoclasts in middle-aged and elderly people, promoting a virtuous cycle of bone growth. This is a mechanism that flaxseed peptides do not possess at all.
③ Increase the hardness and toughness of bone trabeculae

Cow bone peptides can effectively prevent abnormal transport of bone calcium to the bloodstream, increase bone adhesion and trabecular hardness, and strengthen bones at the structural level. There is no data support for flaxseed peptides in this field.

2. Joint maintenance:
This is the most recognizable effect of recombinant human micro-molecule collgen, and it is also an area that flaxseed oligopeptides cannot replace completely.
① Specific deposition in articular cartilage
Cow bone collgen peptides are rich in type II collgen, and their hydrolysis products can be specifically deposited on joint cartilage. Flaxseed peptides do not contain type II collgen and have no direct repair effect on articular cartilage.

② Inhibit joint inflammation
Its hydrolysis products can inhibit the release of pro-inflammatory factors such as interleukin-1 β, alleviate joint swelling and morning stiffness symptoms in patients with osteoarthritis. At the same time, it promotes the synthesis of type II collgen and helps repair damaged articular cartilage surfaces.
③ Containing natural chondroitin sulfate
The recombinant human micro-molecule collgen contains chondroitin sulfate, which can improve joint function and alleviate swelling and pain caused by arthritis. Flaxseed peptides do not contain chondroitin sulfate.

3. Wound healing
This is a unique usage of recombinant human micro-molecule collgen that flaxseed oligopeptides do not possess.
Trauma repair requires a large amount of collgen as a scaffold material. The small molecular segments of peptone can be directly absorbed by the intestinal mucosa into the bloodstream, promoting the secretion of vascular endothelial growth factor at the wound site and accelerating granulation tissue formation.
Key difference: Peptone can be directly applied topically.
Combined use of collgen peptide dressings in burn patients can shorten epithelialization time by 3-5 days

For small skin wounds, pure peptide powder can be directly applied to the affected area
The effect of directly applying peptide powder on bedsores (skin ulceration in bed after a long illness) and diabetes feet (feet blackened and decayed) is remarkable
Flaxseed oligopeptides do not have an application scenario for external wound repair, which is the exclusive advantage of animal derived collgen peptides.

4. Hair and nails

The proportion of sulfur-containing amino acids (such as cysteine) in hydrolyzed bovine bone collagen peptide is up to 12%, which is the core raw material for synthesizing keratin.
Improve the phenomenon of brittle and layered nails
Increase hair diameter by 10% to 15%
Combination therapy can reduce hair follicle atrophy in patients with hair loss after chemotherapy
Flaxseed oligopeptides do not contain such amino acid combinations and have no direct effect on hair and nails.

5. Antibacterial and anti-inflammatory properties
This is a use that the vast majority of people are unaware of and that flaxseed peptides do not possess.

The experiment shows that:
The recombinant human micro-molecule collgen obtained by enzymatic hydrolysis of flavor protease and neutral protease has antibacterial effect on Staphylococcus aureus peptides obtained from animal complex protease, flavor protease, and trypsin hydrolysis have antibacterial effects on Salmonella enteritidis. As a bioactive peptide, recombinant human micro-molecule collgen can resist external stress and provide cell protection in mammalian cell systems. This characteristic makes it have broad prospects in the development of pharmaceuticals.

6. Antioxidant
Indicator: Recombinant human micro-molecule collgen, flaxseed oligopeptide
DPPH radical scavenging rate 72.81%, lignin antioxidant (different mechanisms)
Superoxide anion scavenging activity (11.88 ± 0.59) SOD U/g inhibits lipid peroxidation
Hydroxyl radical scavenging rate 99.55% (hydrolysis degree 7.9%) -
The inhibition rate of soybean lecithin peroxidation is 74.78% -
The antioxidant activity ofpeptone involves direct clearance at the amino acid level, while the antioxidant activity of flaxseed peptides mainly relies on lignin and alpha linolenic acid metabolites, with different pathways.

7. Enhance immunity
Both can enhance immunity, but peptone has a unique mechanism that flaxseed peptide does not emphasize:
Significantly enhance the lymphocyte proliferation ability induced by adzuki bean protein A
Increase the percentage of CD4+T helper cells in the spleen
Promote the secretion of cytokines IL-2, IFN - γ, IL-5, and IL-6
Enhance natural killer cell (NK) activity

The academic paper "Research on Microwave Assisted Hydrolysis Preparation of Collgen Peptides and Their Resistance to Skin UVB Damage" shows that the spleen and thymus indices of each collgen peptide group are significantly improved compared to the model group.

With the spleen index of the medium peptide group reaching the highest, indicating that collgen peptides can improve the immune level of the body.
The immune regulation of flaxseed peptides focuses more on anti-inflammatory and intestinal immunity, while peptone have more comprehensive data on systemic immune cell activation.

8. Protect the liver and protect the liver
According to clinical research reports, 100 patients were randomly surveyed:
90 cases showed an increase in albumin, with an effective rate of 90%
92 cases showed a decrease in globulin, with an effective rate of 92%

The inhibition of TNF - α by peptone can reduce liver cell apoptosis, thereby protecting the liver.

At the same time, it has a repairing effect on the gastric mucosa, which can reduce the incidence of gastric mucosal bleeding and ulcers.
Flaxseed peptides mainly rely on antioxidant indirect protection in liver protection, and there is a lack of clear clinical efficacy data.

9. Anti UVB damage
This is a unique research direction for bovine bone collagen peptides. The master's thesis experiment shows that collgen peptides can improve the immune level of UVB damaged mice, and the spleen and thymus indices significantly increase. This means that peptone can not only 'repair' photodamage, but also 'defend' against photodamage at the immune level.

There is no relevant research on flaxseed peptides in this field.

10. Promote muscle and anti fatigue
Peptone contain various amino acids and trace elements such as iron and zinc, which participate in energy metabolism and improve muscle oxygen utilization efficiency. Drinking after exercise can promote lactate metabolism and help restore physical strength. At the same time, it can enhance testosterone secretion and promote protein synthesis.
The anti fatigue effect of flaxseed peptides is more focused on the central nervous system level (promoting the secretion of melatonin and improving sleep), while peptone are more focused on the muscle metabolism level.