Capromorelin Oral Solution
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Capromorelin Oral Solution

Capromorelin Oral Solution

1.General Specification(in stock)
(1)Injection
Customizable
(2)Tablet
Customizable
(3)API(Pure powder)
PE/Al foil bag/ paper box for Pure powder
HPLC≥99.0%
(4)Pill press machine
https://www.achievechem.com/pill-press
2.Customization:
We will negotiate individually, OEM/ODM, No brand, for secience researching only.
Internal Code: BM-1-105
Capromorelin CAS 193273-66-4
Analysis: HPLC, LC-MS, HNMR
Technology support: R&D Dept.-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of capromorelin oral solution in China. Welcome to wholesale bulk high quality capromorelin oral solution for sale here from our factory. Good service and reasonable price are available.

 

Capromorelin oral solution is a selective growth hormone releasing hormone receptor agonist. It appears as a clear liquid and is specifically designed for dogs. By precisely mimicking and enhancing the signaling pathway of the endogenous growth hormone-releasing peptide (Ghrelin), it effectively stimulates the pulsatile release of growth hormone from the anterior pituitary gland, thereby promoting the synthesis of insulin-like growth factor-1. This mechanism not only significantly enhances the appetite of affected dogs, effectively combating anorexia and muscle atrophy caused by chronic diseases, aging, or post-operative recovery periods, but also helps restore body weight, enhance muscle mass and strength by promoting protein synthesis and improving body composition. This oral solution provides a new drug intervention method for managing cachexia syndrome in dogs and metabolic problems related to muscle loss. Its convenient administration method also greatly improves treatment compliance and the quality of life of affected dogs.
Formulation form and specifications:
Capromerelin Oral Solution exists in the form of an oral solution for easy administration and dosage adjustment. Common specifications include solutions of different concentrations to meet the needs of dogs of different weights and conditions. The specific specifications may vary by manufacturer and region, but are usually expressed in milligrams of Capromerelin per milliliter of solution.

 
Our product
 
Capromorelin Tablet | Shaanxi BLOOM Tech Co., Ltd
Capromorelin Tablet
Capromorelin Oral Solution | Shaanxi BLOOM Tech Co., Ltd
Capromorelin oral solution
Capromorelin Oral Solution | Shaanxi BLOOM Tech Co., Ltd
Capromorelin oral solution

 Produnct Introductionproduct-15-15

Additional information of chemical compound:

Product Name Capromorelin Tablet Capromorelin Oral Solution
Product Type Tablet Solution
Product Purity ≥99% ≥99%
Product Specifications Customizable Customizable
Product Package Customizable

 

Customizable

Capromorelin +. COA

GS-441524 injection name | Shaanxi BLOOM Tech Co., Ltd

Certificate of Analysis

Compound name

Capromorelin

CAS No.

193273-66-4

Grade

Pharmaceutical grade

Quantity

Customized

Packaging standard

Customized
Manufacturer Shaanxi BLOOM TECH Co., Ltd

Lot No.

20250109001

MFG

Jan 12th 2025

EXP

Jan 8th 2029

Structure

Capromorelin structure | Shaanxi BLOOM Tech Co., Ltd

TEST STANDARD GB/T24768-2009 Industry. Stnndard

Item

Enterprise standard

Analysis result

Appearance

White or almost white powder

Conformed

Water content

≤4.5%

0.30%

Loss on drying

≤1.0%

0.15%

Heavy Metals

Pb≤0.5ppm

N.D.

As≤0.5ppm

N.D.

Hg≤0.5ppm

N.D.

Cd≤0.5ppm

N.D.

Purity (HPLC)

≥99.0%

99.5%

Single impurity

<0.8%

0.48%

Residue on ignition

<0.20%

0.064%

Total microbial count

≤750cfu/g

80

E. Coli

≤2MPN/g

N.D.

Salmonella

N.D. N.D.

Ethanol (by GC)

≤5000ppm

400ppm

Storage

Store in a sealed, dark and dry place at-20 degrees

Capromorelin nmr | Shaanxi BLOOM Tech Co., Ltd

GS-441524 injection page footing | Shaanxi BLOOM Tech Co., Ltd

 

Usage

Capromorelin oral solution, as a novel appetite stimulant, has demonstrated significant application value in the field of pet medicine. It simulates the action of endogenous Ghrelin, activates Ghrelin receptors, stimulates appetite, promotes growth hormone secretion, and provides an effective treatment for dogs and cats with loss of appetite.

Loss of appetite caused by chronic diseases
 

1. Chronic kidney disease
Chronic kidney disease is one of the common chronic diseases in dogs and cats. As the condition progresses, pets often experience symptoms of loss of appetite. Capromerelin Oral Solution can be used to treat loss of appetite caused by chronic kidney disease. During the development of chronic kidney disease, due to impaired kidney function and accumulation of toxins in the body, pets' digestive and central nervous systems can be affected, leading to decreased appetite. Capromerelin Oral Solution can activate ghrelin receptors, stimulate the appetite center, and stimulate pets' desire to eat, thereby increasing food intake. By improving appetite, pets can be provided with more nutritional support, which helps maintain their physical function, delay the progression of the disease, and improve their quality of life.

2. Cancer
Cancer patients often experience adverse reactions such as loss of appetite, nausea, vomiting, etc. during the treatment process, such as chemotherapy, radiotherapy, etc. Chemotherapy drugs can damage the gastrointestinal mucosa and affect digestive function, while radiation therapy may also cause certain irritation to the gastrointestinal tract, leading to decreased appetite in pets.

Capromorelin Oral Solution uses | Shaanxi BLOOM Tech Co., Ltd

 

Capromorelin Oral Solution uses | Shaanxi BLOOM Tech Co., Ltd

Capromerelin Oral Solution can help cancer pets increase their appetite and increase their food intake. Adequate nutritional intake is crucial for the physical recovery and maintenance of immune system function in pets with cancer. By improving the nutritional status, pets can enhance their resistance, better tolerate treatment, improve treatment effectiveness, and prolong survival time.

3. Liver disease
Liver disease can also affect pets' appetite, leading to insufficient nutrient intake. The liver is an important metabolic organ. When the liver undergoes pathological changes, it can affect the metabolism and absorption of nutrients, as well as cause imbalances in hormones and neurotransmitters in the body, thereby affecting appetite. Capromorelin solution can stimulate appetite, promote food intake, and improve the nutritional status of pets. Providing necessary nutritional support for liver repair and regeneration helps to restore liver function and improve the overall health of pets.

Loss of appetite caused by age-related sexual dysfunction
 

As dogs and cats age, their physical functions gradually decline, often resulting in problems such as loss of appetite and weight loss. The digestive system function of elderly pets is weakened, teeth wear out, chewing and digestive abilities decrease, and the body's metabolism slows down, resulting in changes in their nutritional needs. Capromerelin Oral Solution can be used to treat loss of appetite caused by age-related sexual dysfunction. It can increase the appetite and food intake of pets, and improve their nutritional status. At the same time, the promotion of growth hormone secretion by Capromerelin Oral Solution helps maintain muscle mass and physical function in elderly pets, reduce the occurrence of muscle loss and weight loss, and improve the physical strength and quality of life of elderly pets.

Capromorelin Oral Solution uses | Shaanxi BLOOM Tech Co., Ltd

Appetite management during postoperative rehabilitation period

 

Capromorelin Oral Solution uses | Shaanxi BLOOM Tech Co., Ltd

After surgery, dogs and cats may be in a state of stress and may experience loss of appetite. Surgical trauma can cause an inflammatory response in the body, releasing inflammatory mediators that affect the central nervous system and digestive system of pets, leading to decreased appetite. Timely administration of Capromorelin solution can stimulate appetite and promote nutrient intake. Adequate nutrient intake can accelerate wound healing, enhance pets' immunity, and reduce the occurrence of complications. During the postoperative recovery period, good nutritional status is crucial for the physical recovery of pets, and Capromorelin solution can help pets recover their health as soon as possible.

Other special circumstances
 

1. Appetite regulation under stress state
Pets may experience loss of appetite when moving, fostering, or changing owners. Stress can cause changes in hormone levels in pets, such as increased secretion of adrenaline and cortisol, which can affect their appetite center and cause them to experience anorexia. Capromerelin Oral Solution can help regulate pets' appetite, enabling them to maintain good nutrient intake even under stress. By improving appetite, the impact of stress on pets' bodies can be reduced, maintaining their physical function and health status.

2. Adjuvant treatment for certain specific diseases
During the treatment of certain diseases, such as inflammatory bowel disease, pets may experience loss of appetite. Inflammatory bowel disease can cause inflammation and damage to the intestinal mucosa, affecting the digestion and absorption of food. It can also cause symptoms such as abdominal pain and diarrhea, leading to decreased appetite in pets. Capromerelin Oral Solution can be used as an adjuvant therapy to increase pet appetite, increase food intake, and improve nutritional status. Good nutritional status helps enhance pets' immunity, promote the repair of intestinal mucosa, and improve the effectiveness of disease treatment.

Capromorelin Oral Solution uses | Shaanxi BLOOM Tech Co., Ltd

 

Capromorelin oral solution has important indications for the treatment of loss of appetite caused by chronic diseases, age-related sexual dysfunction, postoperative recovery, and other special circumstances. It provides an effective treatment for dogs and cats with loss of appetite by stimulating appetite and promoting growth hormone secretion, helping to improve the nutritional status of pets and enhance their quality of life and health. However, in the process of use, it is necessary to strictly follow the advice of veterinarians, pay attention to dosage adjustment, administration time, observation of reactions, drug interactions, and storage conditions, etc., to ensure the safe and effective use of drugs.

Functions

Capromorelin Oral Solution | Shaanxi BLOOM Tech Co., Ltd

Main purpose

 

1. Treatment for loss of appetite
Loss of appetite is one of the common clinical symptoms in dogs and cats, which may be caused by various diseases such as chronic kidney disease, cancer, liver disease, and age-related sexual dysfunction. Capromerelin Oral Solution, as an appetite stimulant, can significantly increase the appetite and food intake of dogs and cats. It activates ghrelin receptors, stimulates the appetite center, and induces a desire to eat in pets, thereby improving their nutritional status and weight management.

2. Improve nutritional status
For dogs and cats suffering from malnutrition due to loss of appetite, Capromorelin solution can help them increase their food intake and improve their nutritional status.

 

Adequate nutrient intake is crucial for the physical recovery, immune system function maintenance, and overall health of pets. By using Capromorelin solution, pets can improve their nutritional levels, enhance their resistance, and promote disease recovery.
3. Promote the secretion of growth hormone
Capromerelin Oral Solution not only stimulates appetite, but also promotes the secretion of growth hormone. Growth hormone plays an important role in the growth and development, muscle synthesis, and fat metabolism of dogs and cats. In elderly dogs and cats or pets with insufficient growth hormone secretion due to illness, using Capromorelin solution can promote the secretion of growth hormone, improve muscle mass, reduce fat accumulation, and enhance the physical strength and vitality of pets.

Capromorelin Oral Solution | Shaanxi BLOOM Tech Co., Ltd

Other properties

Clinical research and effectiveness

1. Clinical trial design

Multiple clinical trials have evaluated the efficacy and safety of Capromerelin Oral Solution in the treatment of canine anorexia. These trials typically adopt a randomized, double-blind, placebo-controlled design to evaluate the effect of Capromorelin Oral Solution on increasing appetite and food intake compared to placebo.

 

2. Clinical efficacy

Clinical trial results have shown that Capromerelin Oral Solution can significantly increase the appetite and food intake of dogs. In a 4-day randomized, double-blind, placebo-controlled trial, healthy adult beagle dogs treated with Capromerelin Oral Solution showed a significant increase in food intake, which was statistically significant compared to the placebo group. In addition, Capromorelin solution can significantly increase the weight of dogs, indicating its effectiveness in improving nutritional status and weight management.

 

3. Security assessment

In clinical trials, the safety of Capromerelin Oral Solution has also been fully evaluated. The results showed that Capromerelin Oral Solution had good tolerability at the recommended dose and no serious adverse reactions were observed. Common adverse reactions include mild salivation, but these reactions are usually self limiting and can be relieved on their own without special treatment.

 

Clinical research support:
Multiple clinical trials have evaluated the efficacy and safety of Capromerelin Oral Solution in the treatment of loss of appetite in dogs and cats. In a 5-month efficacy study report, cats with stable chronic kidney disease were treated with Capromerelin Oral Solution, and the results showed that the treatment group's cats increased their average weight by 5% in just 56 days, while the control group's cats decreased by an average of 1.6% during the same period. Many treated cats showed significant improvement in weight after just two weeks. In another study, healthy adult beagle dogs treated with Capromerelin Oral Solution showed a significant increase in food intake, which was statistically significant compared to the placebo group. These clinical research results fully demonstrate the effectiveness and safety of Capromerelin Oral Solution in treating loss of appetite in dogs and cats.

Manufacturing Information

 

Comparison of Capromerelin with Other Appetite Stimulating Agents

01/

Comparison with traditional appetite stimulants:
Traditional appetite stimulants such as mirtazapine and cyproheptadine can increase the appetite of dogs to some extent, but they often have significant side effects and unstable effects. In contrast, as a new type of appetite stimulant, it has higher selectivity and lower risk of side effects. It can stimulate appetite by simulating the action of endogenous ghrelin, while avoiding interference with other neurotransmitter systems.

02/

Comparison with other new appetite stimulants:
With the continuous development of the pet medical field, more and more new appetite stimulants are being developed. These new appetite stimulants have their own characteristics in terms of mechanism of action, efficacy, and safety. However, with its unique pharmacological effects and good clinical efficacy, it stands out among new appetite stimulants. It can not only significantly increase the appetite and food intake of dogs, but also improve their nutritional status and weight management, providing strong protection for their health.

Capromorelin oral solution, as a new type of appetite stimulant for dogs, has shown broad application prospects in the field of pet medicine due to its unique pharmacological effects and good clinical efficacy. It can significantly increase the appetite and food intake of dogs, improve their nutritional status and weight management, and provide strong protection for their health.

 

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