Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of selamectin injection in China. Welcome to wholesale bulk high quality selamectin injection for sale here from our factory. Good service and reasonable price are available.
Selamectin injection is a semi synthetic macrocyclic lactone compound with the chemical formula C43H63NO11, a molecular weight of 769.96 g/mol, and a CAS number of 220119-17-5. Its appearance is white or almost white hygroscopic powder, with a density of 1.4 ± 0.1 g/cm ³, a boiling point of 917.0 ± 65.0 ° C (760 mmHg), and a flash point of 508.4 ± 34.3 ° C. Celastrol has a high solubility in DMSO, reaching ≥ 100 mg/mL (129.88 mM), but its solubility in water is extremely low. When stored in powder form, the drug needs to be placed at -20 ° C and has an expiration date of 3 years; If dissolved in a solvent, it needs to be stored at -80 ° C and the shelf life is shortened to 1 year. Ice packs should be used to maintain low temperature during transportation to ensure drug stability.
Drug Formulation and Specifications:
The commonly used celericin preparations on the market are injection solutions with various specifications, such as 10 mM/1 mL DMSO solution, or powder packaging of different qualities such as 1 mg, 5 mg, and 10 mg. The prices offered by different suppliers may vary, for example, the price range for 100 mg powder is between ¥ 67.90 and ¥ 2590, depending on the supplier and purity requirements.
Our product
Additional information of chemical compound:
| Product Name | Selamectin Spray | Selamectin Injection |
| Product Type | Spray | Injection |
| Product Purity | ≥99% | ≥99% |
| Product Specifications | Customizable | Customizable |
| Product Package | Customizable |
Customizable |
Selamectin+. COA
 |
||
Certificate of Analysis |
||
|
Compound name |
Selamectin | |
|
CAS No. |
220119-17-5 | |
|
Grade |
Pharmaceutical grade | |
|
Quantity |
Customized | |
|
Packaging standard |
Customized | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
|
Lot No. |
20250109001 |
|
|
MFG |
Jan 12th 2025 |
|
|
EXP |
Jan 8th 2029 |
|
|
Structure |
|
|
| TEST STANDARD | GB/T24768-2009 Industry. Stnndard | |
|
Item |
Enterprise standard |
Analysis result |
|
Appearance |
White or almost white powder |
Conformed |
|
Water content |
≤4.5% |
0.30% |
| Loss on drying |
≤1.0% |
0.15% |
|
Heavy Metals |
Pb≤0.5ppm |
N.D. |
|
As≤0.5ppm |
N.D. | |
|
Hg≤0.5ppm |
N.D. | |
|
Cd≤0.5ppm |
N.D. | |
|
Purity (HPLC) |
≥99.0% |
99.5% |
|
Single impurity |
<0.8% |
0.48% |
|
Residue on ignition |
<0.20% |
0.064% |
|
Total microbial count |
≤750cfu/g |
80 |
|
E. Coli |
≤2MPN/g |
N.D. |
|
Salmonella |
N.D. | N.D. |
|
Ethanol (by GC) |
≤5000ppm |
400ppm |
|
Storage |
Store in a sealed, dark and dry place at-20 degrees |
|
|
|
||
Selamectin injection, as a macrocyclic lactone antiparasitic drug, plays an important role in veterinary clinical practice. It interferes with the parasite's neural transmission system, causing paralysis and death of the parasite, thus achieving the purpose of deworming. Seramycin injection, as one of its common dosage forms, has the advantages of convenient use and rapid absorption, and is widely used in the prevention and treatment of pet parasitic infections.
Clinical application
1. Flea infection
Fleas are common ectoparasites in dogs, which not only cause skin itching, allergies, and other problems, but may also spread other diseases. Ceramycin injection has a highly effective killing effect on fleas. Clinical studies have shown that the number of fleas on dogs significantly decreases in a short period of time after using the recommended dosage of Celaserin injection. For example, under laboratory conditions, within 6 hours of administration, adult fleas completely lose their motility, and the 24-hour mortality rate exceeds 95%. Under natural infection conditions, regular use of Celastrol injection can effectively control flea infections and reduce the harm of fleas to dogs.
2. Ear mite infection
Ear mites are common parasitic infections in the ears of dogs, which can cause symptoms such as itching and increased secretions in the ears. Ceramycin injection also has a good therapeutic effect on ear mites.
Multiple studies have shown that the infection of canine ear mites is significantly improved after using the recommended dosage of Celaserin injection. For example, for domestic dogs naturally infected with ear mites, on the 30th day after medication, all dogs recovered without clinical symptoms such as itching and dandruff.
3. Scabies mite infection
Scabies mite infection can cause severe skin itching, hair loss, and other symptoms in dogs, seriously affecting their quality of life. Ceramycin injection has a good killing effect on scabies mites. According to the recommended dosage, once every 2 weeks, topical application of Celaserin injection was used to treat dogs infected with scabies mites, with an effective rate of 100% and no recurrence. For some severe cases of scabies mite infection, multiple doses may be necessary to achieve better treatment outcomes.
4. Ascaris and hookworm infections
Ascaris and hookworm are common intestinal parasites in dogs, which can cause symptoms such as indigestion and malnutrition.
Ceramycin injection has a killing effect on intestinal nematodes such as canine roundworm and hookworm. The protection period of a single administration can reach more than 30 days, which can effectively control the infection of intestinal nematodes in dogs. The monthly use of Celastrol Injection before and after delivery in dogs has shown good efficacy in treating and controlling intestinal nematode infections in pregnant, lactating dogs, and newborn puppies.
5. Prevention of Lymphatic Filariasis
Canine filariasis is a serious parasitic disease that can cause symptoms such as breathing difficulties, heart failure, and even life-threatening conditions in dogs. Serramycin injection can effectively prevent canine heartworm disease. Using Seramycin Injection once a month can significantly reduce the risk of canine heartworm infection. For example, when dogs living in areas prone to heartworm infection were given monthly injections of Celastrol, after the heartworm infection season, the dogs that used the medication did not develop heartworm infection, while a certain proportion of the control group dogs that did not use the medication were infected with heartworm.
Prevention and treatment of parasitic infections in cats
1. Flea infection
Cats are also susceptible to flea infections, which can cause skin itching, allergies, and other issues. Ceramycin injection has a highly effective bactericidal effect on cat flea infections. After using the recommended dosage, it can effectively reduce the number of fleas on cats and control flea infections. For example, in clinical practice, the use of Celastrol injection to treat cat flea infections can completely eliminate external parasites after 72 hours.
2. Ear mite infection
Cat ear mite infection is quite common and can cause symptoms such as itching and increased secretions in the ears of cats. Ceramycin injection has a good therapeutic effect on cat ear mite infection. After using the recommended dosage, the infection of cat ear mites was significantly improved, which can quickly alleviate the symptoms of cats' ears.
3. Ascaris and hookworm infections
The cat head roundworm and the tubular hook mouth nematode are common intestinal parasites in cats. Ceramycin injection has a bactericidal effect on intestinal nematode infections in cats. It can effectively control the number of intestinal nematodes in cats and reduce the harm of parasites to cat health.
4. Lice infection
Lice is also one of the common ectoparasites in cats. Ceramycin injection has a bactericidal effect on lice such as cat lice. After using the recommended dosage, it can significantly reduce the number of lice on cats and achieve the goal of treating lice infections.
3.3 Prevention and treatment of parasitic infections in other small mammals
Ceramycin injection can also be used for the prevention and treatment of parasitic infections in small mammals such as minks, rabbits, and rodents. For these small mammals, using Seramycin Injection at a dose of 6 mg/kg per month can effectively prevent and treat common parasitic infections such as fleas and mites. However, it should be noted that the dosage of celericin injection for birds and reptiles is currently unclear and requires further research and exploration.
Indications
1. External parasite infection
Ceramycin injection is suitable for treating and preventing external parasitic infections in pets such as dogs and cats, including fleas, ear mites, scabies mites, lice, etc. These ectoparasites not only cause pet skin itching, allergies, and other problems, but may also spread other diseases, seriously affecting the health and quality of life of pets. The use of Celastrol injection can effectively eliminate these external parasites and protect the health of pets.
2. Parasitic infection in the body
Ceramycin injection can be used to treat parasitic infections in dogs and cats, such as intestinal nematodes such as roundworms and hookworms.
Intestinal nematode infection can cause symptoms such as indigestion and malnutrition in pets, affecting their growth, development, and health. Ceramycin injection can kill these intestinal nematodes and restore the intestinal health of pets.
3. Prevention of Lymphatic Filariasis
Canine filariasis is a serious parasitic disease that poses a great threat to the health of dogs. Seramycin injection is one of the effective drugs for preventing canine heartworm disease. Using Seramycin Injection once a month can effectively reduce the risk of heartworm infection in dogs and protect their heart health.
Clinical application case analysis
1. Cases of canine mixed infection
A pet hospital received a dog infected with both fleas and roundworms. The veterinarian treated the dog with selamectin injection based on its weight and infection status. After subcutaneous injection at the recommended dose of 6 mg/kg body weight, fleas were completely eliminated from the dog's body after 72 hours, and fecal egg detection turned negative after 14 days. This indicates that Seramycin injection has a good therapeutic effect on mixed infections in dogs and can simultaneously drive away parasites both inside and outside the body.
2. Cases of cat ear mite infection
A domestic cat experienced symptoms such as ear itching and increased secretions, and was diagnosed with ear mite infection after examination. The veterinarian administered Celastrol Injection for treatment, administered subcutaneously at the recommended dose of 6 mg/kg body weight. On the 30th day after medication, the symptoms of ear mite infection in cats completely disappeared, without clinical symptoms such as itching and dandruff. This demonstrates the effective therapeutic effect of Seramycin injection on cat ear mite infection.
Seramycin injection, as a broad-spectrum antiparasitic drug, has important application value in the prevention and treatment of parasitic infections in pets such as dogs and cats. It interferes with the parasite's neural transmission system, causing paralysis and death of the parasite, thus achieving the purpose of deworming. Seramycin injection is suitable for treating and preventing various parasitic infections both inside and outside the body, including fleas, ear mites, scabies mites, lice, roundworms, hookworms, etc. It can also be used to prevent canine heartworm disease. When using Seramycin injection, it is necessary to strictly follow the recommended dosage and administration method, pay attention to contraindications and adverse reactions, and pay attention to drug interactions. By using Seramycin Injection reasonably, parasitic infections in pets can be effectively controlled and their health can be protected.
Drug preparation and usage methods
Ceramycin powder needs to be dissolved in an appropriate solvent according to experimental requirements. For example, 1 mg of Celastrol can be dissolved in 1.2988 mL DMSO to prepare a 1 mM solution, or dissolved in 0.1299 mL DMSO to prepare a 10 mM solution. Please note that the hygroscopicity of DMSO may affect its solubility, so it is recommended to use newly opened DMSO. The prepared solution should be packaged and stored separately to avoid repeated freeze-thaw cycles leading to drug failure.
In animal experiments, the dosage and volume of medication should be adjusted according to the animal's body weight and experimental design. For example, if the dosage is 10 mg/kg, the average body weight of each animal is 20 g, and the dosage volume is 100 μ L, the total required dosage is 4 mg, and the final concentration of the working solution is 2 mg/mL. The administration routes include intraperitoneal injection, gastric lavage, etc., and the specific selection should be determined according to the experimental purpose and drug characteristics.
Selamectin injection is recommended to use and prepare the working fluid for in vivo experiments to avoid drug degradation caused by long-term storage. If precipitation or precipitation occurs during the preparation process, it can be dissolved by ultrasound or heating. In addition, the dosage should be adjusted according to the animal species and model, for example, the commonly used dosage range for mice is 5-20 mg/kg, while for dogs it may be higher.
Hot Tags: selamectin injection, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale