Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of fipronil powder in China. Welcome to wholesale bulk high quality fipronil powder for sale here from our factory. Good service and reasonable price are available.
Fipronil powder is a broad-spectrum insecticide with non-pirothrin as its highly effective active ingredient. It works by irreversibly blocking the GABA receptors in the insect's central nervous system, causing the pests to become overly excited, convulse, and die. This unique mechanism of action gives it excellent contact and stomachic toxicity against cockroaches, ants, fleas, lice, ticks, and various crop pests, while being relatively safe for mammals. The formulation is typically a fine white to grayish-white powder, made by mixing the original drug with an inert carrier. It is stable in nature and has a long residual period. In practical applications, it can be directly spread as a powder in the areas where pests are active, or formulated into a liquid for spraying, and is widely used in urban and rural public health, pet parasite control, warehouse protection, and integrated pest management in agriculture. It is important to note that due to its extremely high toxicity to bees and aquatic organisms, strict adherence to usage guidelines, control of dosage and methods is necessary to minimize potential risks to non-target organisms and the environment.
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| Fipronil Spot On | Compound Fipronil and Praziquantel Spot On Solution (Fipronil+Methopren+Acetaminobamectin+Praziquantel) |
Compound Fipronil Drops (Fipronil+Methoprene) |
| CAT:0.5ml DOG: (1)0.67ml:2-10kg (2)1.34ml:10-20kg (3)2.68ml:20-40kg (4)4.02ml:40-60kg |
(1)0.3ml (2)0.9ml 1ml:83mg+100mg+4mg+83mg |
CAT:0.5ml:50mg+60mg DOG:1ml:100mg+90mg (1)0.67ml (2)1.34ml (3)2.68ml (4)4.02ml |
Fipronil Powder COA
Environmental Chemical Behavior Decoding
Fipronil Powder, as a broad-spectrum insecticide of the phenylpyrazole class, has been developed by the French company Roquette since 1987. Due to its unique insecticidal mechanism and high efficiency, it has been widely used in global agriculture and hygiene fields. However, its environmental chemical behavior is complex, involving degradation, migration, and residue, posing potential threats to ecosystem safety. The following systematically analyzes the environmental chemical behavior of fluofenphos from four dimensions: degradation characteristics, environmental migration, ecological toxicity, and environmental management.
Degradation characteristics: Slow metabolism through multi-pathway synergy
The degradation of fipronil in the environment is mainly achieved through three pathways: hydrolysis, photolysis, and microbial degradation. However, the overall degradation rate is relatively slow, with a long half-life, resulting in its tendency to form persistent residues in the environment.
Hydrolysis degradation
The hydrolysis rate of fipronil is significantly influenced by pH value and temperature. Under weakly acidic conditions (pH 5.0), the half-life of hydrolysis at 25°C is 144.4 days, and it shortens to 119.5 days at 50°C; in neutral conditions (pH 7.0), the half-life is 123.8 days at 25°C and 39.8 days at 50°C; while in weakly alkaline conditions (pH 9.0), the half-life is only 10.0 days at 25°C and further shortened to 8.1 hours at 50°C. This indicates that high temperature and alkaline environment can significantly accelerate the hydrolysis of fipronil, but it still has strong chemical stability at room temperature.
Photodegradation
Fipronil powder is prone to photodegradation under light conditions. In aqueous phase, the half-life of photodegradation at pH 5.5 is 4.1 hours, showing rapid photodegradation characteristics. However, in soil surface, the photodegradation rate is affected by factors such as soil type, organic matter content, and light intensity, and the half-life can reach 34 days. The photodegradation products mainly include MB46513 and RPA200766, among which the sulfone metabolite (MB46136) is produced in large quantities in the first 3 days after application, and the production amount decreases subsequently.
Microbial degradation
Microorganisms are the dominant factor for the degradation of fipronil in soil. In waterlogged soil, anaerobic bacteria can accelerate the degradation of fipronil, and continuous application also affects its degradation rate. The degradation mechanism of fipronil varies in different soil types: the black soil in Northeast China is mainly oxidative metabolism, the Taihu rice soil is mainly reductive metabolism, and the red soil in Jiangxi shows a combined oxidative-reductive action. The main metabolites include amide metabolite (MB45950) and sulfone metabolite (MB46136), and their growth patterns are affected by soil environmental conditions.
Environmental migration: The dual effects of adsorption and migration
The migration behavior of fipronil in the environment is controlled by its physical and chemical properties and the characteristics of environmental media, showing limited migration ability and potential groundwater pollution risk.
Soil adsorption
The average Koc value of fipronil is 803, indicating that its adsorption on the soil surface is weak and it is prone to migrate from the surface to the deeper layers. However, the migration rate of its sulfur metabolites in the soil is smaller, making it less likely to move to the deeper soil layers, thereby reducing the direct pollution risk to groundwater. Soil organic carbon content is a key factor affecting the adsorption of fipronil. Organic matter can accelerate its degradation and reduce residues.
Water body migration
The solubility of fipronil in water is low (1.9 mg/L at 25°C), but it can enter the water body through surface runoff and soil leaching. In paddy water, fipronil is mainly degraded by photolysis and hydrolysis, with the degradation products mainly being MB46513 and RPA200766. However, its persistence in water bodies may still lead to long-term exposure risks to aquatic organisms.
Ecotoxicity: The dual challenges of high toxicity and broad-spectrum nature
Fipronil has high toxicity to a variety of non-target organisms, and its ecological risk cannot be ignored.
Aquatic toxicity: Fipronil is highly toxic to fish and crustaceans. The 96-hour LC50 for carp is 0.34mg/L, indicating a serious threat to aquatic ecosystems. Moreover, fipronil is lethal to bees, and the poisoning of a single bee can lead to the death of the entire colony of bees, thereby affecting the fruiting rate of crops and other plants.
Bird toxicity: Recent studies have shown that the residual fipronil in pet flea control products can enter bird nests through the birds' nesting behavior, causing the death of chicks or the inability of bird eggs to hatch. In the UK, all tested blue tit and great tit bird nests were contaminated with fipronil, with 100% containing fipronil and 89% containing imidacloprid, causing a devastating impact on bird populations.
Mammalian toxicity: The toxicity of fipronil to mammals is relatively low. The acute oral LD50 for rats is 100mg/kg, the acute dermal LD50 is >2000mg/kg, and the acute inhalation LC50 is 0.682mg/L. However, it is still moderately toxic to humans and livestock, and has potential carcinogenic effects, requiring strict restrictions on its usage range.
Environmental Management: Comprehensive prevention from restricted use to ecological restoration
Given the environmental risks of fipronil, many countries around the world have adopted strict management measures and explored ecological restoration technologies to reduce its environmental impact.
Usage Restrictions
In China, most pesticide formulations containing fipronil have been discontinued for sale and use since 2009, and can only be used for household pest control. The European Union and the United Kingdom have also banned the use of fipronil in the agricultural sector, but still allow it for use in pet flea control products, resulting in an increased risk of exposure for wild birds.
Ecological Restoration
For contaminated soil and water bodies with fipronil, accelerated solvent extraction - gas chromatography technology can be used to quickly extract and determine fipronil and its metabolites in the soil, providing scientific basis for restoration. At the same time, by adding organic matter and adjusting the soil pH value, the microbial degradation of fipronil can be accelerated, reducing residues.
Development of Alternatives
To reduce the environmental risk of fipronil, efforts are needed to accelerate the research and development of new pesticides with low toxicity, high efficiency, and easy biodegradability, and to promote green control technologies such as biological control and physical control, achieving sustainable agricultural development.
Basic Information
Fipronil powder, the English name is Fipronil, its chemical name is 5-amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-acrylonitrile, with a CAS number of 120068-37-3. The pure form is a white or off-white powder, with a molecular formula of C₁₂H₄Cl₂F₆N₄OS and a molecular weight ranging from 437.1478 to 437.15. The melting point range of fipronil is between 196℃ and 201℃, the boiling point is 510.1℃ (under 760 mmHg conditions), the vapor pressure is 3.7×10⁻⁷ Pa (at 20℃), and the partition coefficient (at 25℃) logP is 4.0.
Physical and Chemical Properties
Solubility: Fipronil is insoluble in water, but it has certain solubility in other solvents. For example, at 20℃, its solubility in acetone is 545.9 g/L, in dichloromethane is 22.3 g/L, in toluene is 3.0 g/L, and in hexane is less than 0.028 g/L.
Stability: Fipronil is stable in water with pH = 5 and pH = 7, but it undergoes slow hydrolysis at pH = 9, with a half-life (DT50) of approximately 28 days. Under sunlight exposure, fipronil will slowly degrade, but it can be rapidly decomposed in water solutions upon exposure to light.
Synthesis Process
There are multiple synthesis routes for fipronil. In industrial production in China, the following process route is mostly adopted:
Intermediate synthesis: 5-Amino-3-cyano-1-(2,6-dichloro-4-trifluoromethyl phenyl)pyrazole is used as the intermediate for synthesizing fipronil.
Fipronil synthesis: The above intermediate is synthesized with trifluoromethyl sulfonyl chloride in one step to obtain fipronil.
Applications and Formulations
Fipronil is a broad-spectrum insecticide that can be applied in various ways such as foliar treatment, soil treatment, and seed treatment. Its application scope is wide, including but not limited to:
Leaf spraying: 25-50 grams of active ingredient per hectare, which can effectively control pests such as potato leaf moth, small cabbage moth, powdery leaf moth, Mexican cotton boll weevil and flower thrips.
Paddy field use: 50-100 grams of active ingredient per hectare, which can control pests such as rice borers and brown planthoppers.
Grass pest control: 6-15 grams of active ingredient per hectare, which can control pests of the locust genus and desert locust genus.
Soil treatment: 100-150 grams of active ingredient per hectare, which can effectively control corn root leaf moth, grubs and ground beetles.
Seed treatment: 250-650 grams of active ingredient per 100 kilograms of seeds, which can effectively control corn grubs and ground beetles.
Manufacturing and Packaging
Manufacturing environment
The manufacturing process of fipronil requires to be carried out in a strict chemical synthesis environment to ensure the purity and quality of the product.
Packaging specifications
Fipronil powder is usually packaged in 25 kilograms per barrel, and can also be customized according to customer requirements, such as 1 kilogram, 100 grams, etc.
Storage conditions
Fipronil powder should be stored in a cool, dark and dry environment to prevent its degradation and deterioration.
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