Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of matrixyl 3000 powder in China. Welcome to wholesale bulk high quality matrixyl 3000 powder for sale here from our factory. Good service and reasonable price are available.
Matrixyl 3000 Powder is a high‑activity lyophilized compound peptide powder composed of Palmitoyl Tripeptide‑1 and Palmitoyl Tetrapeptide‑7. Free of glycerin, butanediol and other auxiliary solvents, this matrikine‑type raw material delivers dual effects of dermal matrix activation and inflammatory modulation. Bloomtechz supplies qualified Matrixyl 3000 Powder, backed by complete quality reports, mature technical support and one‑on‑one formulation services to accelerate your cosmetic product development.
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Matrixyl 3000 COA
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| Certificate of Analysis | ||
| Compound name | Matrixyl 3000 | |
| Grade | Pharmaceutical grade | |
| CAS No. | N/A | |
| Quantity | 19g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090055 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure | N/A | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.50% |
| Loss on drying | ≤1.0% | 0.68% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.45% |
| Single impurity | <0.8% | 0.78% |
| Total microbial count | ≤750cfu/g | 98 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 570ppm |
| Storage | Store in cool, dark place or refrigerator | |
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The powder appears as a white to off-white, fine lyophilized powder with no noticeable odor. Because the molecules contain a palmitoyl lipophilic chain, this powder cannot dissolve completely in pure water. It must first be pre-dispersed using short-chain polyols such as propylene glycol or butylene glycol before being added to an aqueous system. This is a critical physicochemical characteristic of this powder formulation and distinguishes it significantly from diluted gel solution products. Industrial-grade powder typically achieves an HPLC purity of 95% or higher. It contains no excipients such as glycerol, carbomer, or polysorbate-20, and its active ingredient content is significantly higher than that of commercially available liquid Matrixyl 3000 gel.
As a highly active powdered ingredient, Matrixyl 3000 Powder is primarily targeted at B2B formulation R&D companies in the cosmetics industry. It is suitable for formulations where users need to independently control carrier solvents and wish to avoid incorporating excipients such as glycerin and butylene glycol. While its application presents a slightly higher barrier to entry compared to ready-made gel solutions, it also offers greater formulation flexibility.
First, it can be used in various anti-aging serums, particularly in anhydrous formulations, low-polyol formulations, and minimalist formulations. Standard commercially available Matrixyl 3000 gels contain significant amounts of glycerin and butylene glycol,
which directly alter the overall polyol content of the formulation;in contrast, the powder form allows formulators to independently select a dispersion solvent and precisely control the total amount of humectants in the formulation, making it suitable for niche segments such as minimalist serums for sensitive skin and glycerin-free serums. Second, it can be used in leave-on anti-aging products such as face creams, lotions, eye creams, and neck creams. During the cooling phase of the formulation, the powder is pre-dispersed before being added to incorporate the signal peptide. Additionally, this powder is suitable for innovative formulations such as freeze-dried skincare sheets, solid masks, and solid serums;
under storage conditions for solid formulations, the peptide powder maintains higher stability.This powder is intended exclusively for leave-on cosmetics and is not recommended for rinse-off products, as rinsing would result in insufficient dwell time for the active ingredient to take effect. From a processing perspective, this peptide is heat-sensitive; during powder dissolution and addition, the system temperature must be maintained below 50°C, and high-temperature addition is strictly prohibited; The powder must not be added directly to purified water; it must first be pre-dispersed using propylene glycol or butylene glycol. Failure to do so may result in agglomeration, floating, or precipitation, leading to uneven dispersion of the active ingredient and abnormal local concentrations.
Formulators must calculate the percentage of active ingredient in the powder based on formulation goals and then determine the dosage;they must not simply adopt the addition percentage used in liquid Matrixyl 3000 gel formulations.Bloomtechz's one-on-one service covers the entire process from initial formulation selection to sample production and implementation. Based on the customer's formulation system, we provide powder pre-dispersion process parameters, recommended dosage ratios, and warnings regarding incompatibilities, helping engineers resolve common issues such as powder dispersion and precipitation, thereby shortening the formulation debugging cycle.
Our experienced sales team can analyze the cost differences between the powder and liquid gel formulations in light of the client's product positioning, providing objective recommendations to facilitate procurement decisions.
The greatest advantage of the Matrixyl 3000 Powder freeze-dried formulation is that, compared to liquid gel products, the storage stability of the solid powder is significantly improved. However, due to the chemical nature of peptides, it is still susceptible to four major factors: temperature, oxygen, light, and humidity, as well as metal ions.
When stored in a sealed container at low temperatures and protected from light, it has a standard shelf life of up to 24 months. Once the powder comes into contact with air or moisture, it rapidly absorbs moisture. After absorbing moisture, the rate of hydrolysis and degradation of the peptide chains accelerates significantly, and purity gradually decreases;
therefore, the powder must be strictly sealed to prevent exposure to moisture.High temperatures accelerate the hydrolysis and breakdown of peptide bonds; even in powder form, prolonged exposure to high temperatures will cause a decline in activity. The recommended storage conditions are 2–8°C in a sealed, light-protected, and dry environment. Short-term transport at room temperature is acceptable, but long-term storage at room temperature is not recommended.Powder addition must be completed during the formulation cooling phase, at a temperature not exceeding 50°C. Under no circumstances should the formulation undergo high-temperature, high-pressure sterilization. Even if the powdered raw material itself meets specifications,
the downstream formulation must still undergo comprehensive accelerated stability testing to assess changes in content and appearance and to confirm the shelf life of the finished product.Bloomtechz's experienced technical support team provides customers with guidelines for powder storage, transportation, and moisture protection, as well as stability reference protocols. We assist customers in conducting accelerated stability testing to help distinguish between degradation of the raw material itself and inactivation caused by the formulation system.Bloomtechz closely follows global trends in the formulation market and continuously optimizes the synthesis, purification,
and freeze-drying processes for Matrixyl 3000 Powder to ensure stable formulation ratios across batches and prevent fluctuations in bioactivity between batches.
Reference
[1] Cosmetic Ingredient Review (CIR) Expert Panel. Safety Assessment of Tripeptide-1, Hexapeptide-12, their Metal Salts and Fatty Acyl Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics[R]. CIR-Safety,2014.
[2] Pickart L. The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging[J]. PMC,2012.
[3] TCS Industries Limited. Formulation Guideline for Palmitoyl Tripeptide-1
[4] PeptideInsight. Palmitoyl Tripeptide-1-Mechanism,Formulation & Comparison
[5] FormBlends. Best Peptides for Wrinkles: Evidence-Ranked Guide
FAQ
Q1: Can the product be added directly to purified water and stirred to dissolve it and prepare a stock solution?
A: No, it should not be added directly to purified water. The lipophilic properties of the palmitoyl chains cause the powder to agglomerate and float, preventing adequate dispersion. The correct procedure is to first pre-disperse the powder using propylene glycol or butylene glycol. After thorough stirring, slowly add it to the aqueous system while maintaining the overall system temperature at ≤50°C. Bloomtechz provides one-on-one technical support and includes a complete quality report with every batch to minimize the risk of formulation failure.
Q2: After Matrixyl 3000 Powder (freeze-dried) is transported at room temperature, can the raw material be immediately deemed ineffective?
A: Short-term transport at room temperature will not directly cause the powder to become completely inactive; however, prolonged exposure to high temperatures and humidity will accelerate moisture absorption and degradation. Upon arrival, it is necessary to test the water activity, peptide HPLC content, and physical appearance, using the test data as the basis for judgment-do not rely solely on subjective visual assessment. As a professional manufacturer, Bloomtechz provides recommendations for transport protection, and our dedicated sales team offers logistics risk alerts to assist customers in implementing post-delivery inspection protocols.
Q3: Can the active ingredients in the product and liquid Matrixyl 3000 gel be directly converted between each other on a percentage basis?
A: A direct, simple percentage conversion is not possible. The liquid gel contains a large amount of carrier solvents such as glycerin and water, while the powder is a pure blend of peptides. The active ingredient bases of the two are completely different, so a precise conversion based on their respective active ingredient contents is required. Bloomtechz technical support can provide customers with conversion examples, assist with calculating dosage amounts, and support comparative sample testing to help customers select the appropriate product.
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