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We don't sale this chemicals, here ONLY for check the basic information of this chemical compound.
Mar. 31th 2025
Lyrica, the main core component is pure pregabalin powder, a white or almost white crystalline powder. For the treatment of peripheral neuralgia, or adjuvant treatment of partial epilepsy. It can also be used to treat anxiety, social phobia and arthritis. At the same time, pregabalin is also suitable for sleep. The sleep dose of pregabalin needs to be determined by the doctor.
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Chemical Formula |
C8H17NO2 |
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Exact Mass |
159 |
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Molecular Weight |
159 |
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m/z |
159 (100.0%), 160 (8.7%) |
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Elemental Analysis |
C, 60.35; H, 10.76; N, 8.80; O, 20.10 |
Additional information of chemical compound: Flash point 9 ℃, Storage conditions 2-8°C, Solubility deionized water: ≥10mg/mL, Acidity coefficient (pKa) 4.23±0.10(Predicted), Appearence white powder
Hazard symbol (GHS), GHS02,GHS06,GHS08,GHS05, Warning word danger, Hazard description h318-h361-h225-h301 + h311 + h331-h370, Precautions p210-p260-p280-p301 + p310-p311-p305 + P351 + P338 + p310-p305 + P351 + P338, Dangerous goods signs xn, t, f, Hazard category code 63-48 / 22-39 / 23 / 24 / 25-23 / 24 / 25-11, Safety instructions 22-36 / 37-45-16-7, Dangerous goods transportation No.: un1230 - class 3 - PG 2 - methanol, solution, WGK Germany 3
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Lyrica's molecular structure analysis indicates that it has unique chemical structure and pharmacological properties. The chiral center and polar groups in its molecule give it high pharmacological activity and water solubility. Meanwhile, the unsaturated nature of its molecular structure also gives it a certain degree of stability. These characteristics collectively determine the important position of Lyrica as an analgesic.
In addition to being used as an analgesic, pregarin is also used to treat various diseases such as epilepsy, anxiety, depression, etc. The pathological and physiological processes of these diseases involve abnormalities in GABA neurotransmission. Therefore, pregarin exerts therapeutic effects by regulating GABA neurotransmission. In addition, pregarin has lower side effects and better tolerance, making it an ideal drug for treating these diseases.
The chiral separation and synthesis of Lyrica are one of the key steps in the production process. Chiral separation can be achieved through methods such as chemical or biological separation. Chemical separation methods include crystallization and chromatography, while biological separation methods utilize biocatalysts such as microorganisms or enzymes to achieve chiral separation. In addition, the synthesis of Lyrica also requires multiple chemical reaction steps to ultimately obtain the target drug.
The above introduction to pure pregabalin powder is for detailed introduction and interpretation from the perspective of the finished product of the product, but our laboratory and scientific researchers are engaged in the work of chemistry. In short, we are responsible for the most basic chemical extraction stage at the front end. We will, according to your requirements and within the scope permitted by the laws of the people's Republic of China, To customize the basic chemicals you need, we firmly reject all things that violate morality and law.
Remark: BLOOM TECH(Since 2008), ACHIEVE CHEM-TECH is the subsidiary of us.
Specific application cases of Pregabalin capsules in the treatment of postherpetic neuralgia (PHN) can be elaborated through the following aspects:
Clinical application cases
A clinical observation randomly divided patients with postherpetic neuralgia into treatment group and control group, 40 cases in each group. The treatment group was treated with it and the control group was treated with carbamazepine. After one month of treatment, the efficacy of the two groups of patients was compared. The results showed that the therapeutic effect of the treatment group was significantly better than that of the control group. The therapeutic effect of the treatment group was 14 cases (35%) of grade I, 20 cases (50%) of grade II, and 6 cases (15%) of grade III, while the therapeutic effect of the control group was 10 cases (25%) of grade I, 16 cases (40%) of grade II, and 14 cases (35%) of grade III. The treatment efficacy was 85% and 65% in the treatment and control groups, respectively. This case shows that it has significant efficacy in the treatment of postherpetic neuralgia.
Combination with other drugs
In addition to the use of it alone, there are clinical cases in which it was combined with other drugs to achieve better therapeutic effects. For example, some studies have reported that the combination of it and liver-sparing capsule for the oral treatment of postherpetic neuralgia has achieved significant therapeutic effects. This combined medication program can more effectively reduce the pain symptoms of patients and improve the quality of life of patients.
the specific method of medication and dosage
In the treatment of postherpetic neuralgia, the dosing method and dosage of Prevacid need to be adjusted according to the specific conditions of patients. Generally speaking, doctors will advise patients to start with a low dose and gradually increase the dose according to the patient's pain level and tolerance. At the same time, doctors will also inform patients of possible side effects and precautions to ensure the safety of the medication.
Assessment of efficacy and safety
During the course of treatment, the doctor will conduct regular assessments of the efficacy and safety of the patient. The efficacy assessment usually includes indicators of pain level, sleep quality and quality of life. The safety assessment focuses on whether the patient experiences any adverse effects, such as dizziness, drowsiness, or dry mouth. If serious adverse reactions or poor efficacy occur, the doctor will promptly adjust the treatment plan.
Patient feedback and follow-up
Many patients reported significant relief of their pain symptoms after receiving Prevacid treatment. Some patients even reported that their pain had completely disappeared and their quality of life had been significantly improved. For patients with remarkable efficacy, doctors will recommend that they continue to take Prevacid for consolidation treatment to prevent the pain from recurring.
In summary, Pregabalin capsule has remarkable efficacy and safety in the treatment of postherpetic neuralgia. Through rational dosing methods and dosage adjustments, as well as regular efficacy and safety assessments, patients can be provided with an effective treatment regimen to improve their quality of life.
What are the side effects of this compound?
Pure Pregabalin Powder is a pharmaceutical intermediate mainly used for the preparation of drugs such as antiepileptic, analgesic, and anti anxiety drugs. However, like other drugs, pregabalin may also have a series of side effects when used. The following is a detailed discussion on its side effects:
Digestive system side effects
Pregabalin has relatively common digestive system side effects, which may include symptoms such as nausea, constipation, bloating, and stomach pain. These symptoms are usually related to direct stimulation of the gastrointestinal tract by medication. In addition, pregabalin may also affect appetite, leading to increased appetite in some patients and subsequently causing weight gain. Although this weight change may not necessarily be pathological, it may have a certain impact on the patient's psychological state and quality of life.
Muscle and coordination side effects
Pregabalin may also cause muscle and coordination related issues. Patients may experience muscle spasms, unconscious body tremors, and even loss of balance and coordination. These symptoms may interfere with patients' daily activities, especially in situations that require fine manipulation or maintaining body balance. In extreme cases, swelling may also occur in the arms, legs, or hands and feet, although such adverse reactions are relatively rare.
Neurological side effects
As a drug that affects the central nervous system, pregabalin may also cause a series of neurological side effects. These side effects may include dizziness, drowsiness, memory loss, and lack of concentration. These symptoms may affect the patient's cognitive function and daily life, especially in situations that require high concentration and quick reflexes. In addition, pregabalin may also cause visual problems such as blurred vision and ghosting, further affecting the patient's daily life and work efficiency.
Psychological disorders and emotional changes
The use of Pregabalin may also have an impact on the psychological state of patients. Some patients may feel anxious, depressed, or emotionally unstable. These emotional changes may be related to the effects of drugs on neurotransmitters, as well as patients' concerns and discomfort about drug side effects. In extreme cases, patients may also experience suicidal thoughts or manic behavior, which requires close monitoring and timely intervention by medical professionals.
Skin and allergic reactions
Pregabalin may also cause skin side effects such as urticaria, rash, itching, and blistering. These symptoms are usually related to patients' allergic reactions to medication. When these skin symptoms occur, patients should immediately stop using Pregabalin and seek medical assistance. In addition, pregabalin may also cause more severe allergic reactions such as facial or eye swelling, which also require urgent medical intervention.
other side-effects
Pregabalin may also cause a range of other symptoms. These symptoms may include difficulty breathing, increased or decreased heart rate, changes in blood pressure, and hematuria. These symptoms are usually severe and may endanger the patient's life safety. Therefore, when using Pregabalin, patients should closely monitor their physical condition and seek medical attention immediately if any discomfort symptoms occur.
Side effects of special populations
Pregnant and lactating women: Pregabalin may have adverse effects on the fetus, so pregnant women should use it with caution. Meanwhile, as pregabalin may be secreted through breast milk, lactating women should also stop breastfeeding during the medication period.
Children and Adolescents: The safety and efficacy of Pregabalin in children and adolescents have not been fully validated. Therefore, patients under the age of 17 should not use pregabalin.
Elderly people: Elderly people may be more sensitive to pregabalin, so the dosage should be adjusted appropriately when using it and its side effects should be closely monitored.
Patients with renal insufficiency: As pregabalin is mainly excreted and cleared through the kidneys, patients with renal insufficiency may need to adjust the dosage when using it to avoid the accumulation of the drug in the body and worsening of side effects.
Management and prevention of side effects
Pregabalin F may interact with other drugs, leading to increased side effects. Therefore, when using pregabalin, patients should inform their doctors of the other medications they are currently using so that doctors can assess the risk of drug interactions. Therefore, patients should closely monitor their physical condition and seek medical attention immediately if any discomfort symptoms occur. Medical professionals should also regularly follow up and monitor patients to detect and manage side effects in a timely manner. They can also reduce the side effects of Pure Pregabalin Powder by adjusting their lifestyle. For example, maintaining sufficient sleep, balanced diet, and appropriate exercise. These measures help enhance the patient's immune system and reduce the burden of medication on the body.
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