Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of tetracaine hcl powder cas 136-47-0 in China. Welcome to wholesale bulk high quality tetracaine hcl powder cas 136-47-0 for sale here from our factory. Good service and reasonable price are available.
Tetracaine HCl powder (CAS 136-47-0) is a water-soluble local anesthetic widely used in laboratory R&D and in chemical and pharmaceutical production processes, where its key physical properties - melting point, solubility, thermal stability, photostability, density, and refractive index - are directly tied to purity: the higher the purity, the more stable and consistent these characteristics become. As a light-sensitive compound that readily undergoes photodegradation, it demands careful handling from production through delivery, which is exactly why Blomtechz pairs every batch with light-protective packaging, strict quality control, and clear storage guidance, so the material reaches your lab or production line in stable, reproducible condition. With reliable supply and responsive technical support, Blomtechz makes sourcing this critical pharmaceutical ingredient as straightforward as it should be.
Therefore, it is necessary to protect it from light exposure during storage. The density is 1.08 g/cm ^ 3 (25 ℃). In the liquid or gas state, this value may vary. The refractive index is 1.535 (20 ℃). Like the melting point, the refractive index is related to its purity, and high-purity It has a higher refractive index. Various chemical reactions such as carboxylation, alkylation, oxidation, chlorination, and reduction can be carried out in solution. The laboratory has accurately determined his chemical information, and the results are as follow:
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Chemical Formula |
C15H25ClN2O2 |
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Exact Mass |
35.98 |
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Molecular Weight |
36.46 |
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m/z |
204 (100.0%), 205 (11.9%), 206 (4.5%) |
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Elemental Analysis |
C, 64.67; H, 5.92; N, 13.71; S, 15.69 |
Other information of chemical compound:
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Morphological |
Solid or Viscous Liquid |
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refractive index |
1.5200 ( estimate ) |
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Melting point |
149 °C |
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Boiling point |
403.5 °C |
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Density |
1.1279 ( rough estimate) |
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Storage conditions |
2-8 °C |
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solubility alcohol |
solublesoluble 40 parts of solvent |
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Acidity coefficient ( pKa ) |
8.39 ( at 25 °C ) |
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Soluble in water |
50mg / ml |
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Tetracaine hcl powder is an organic synthetic intermediate and pharmaceutical intermediate, which is mainly used in laboratory research and development process and chemical and pharmaceutical production process.
Photochemical reaction:
Tetracaine Hydrochloride is susceptible to the influence of light, and ultraviolet and blue purple light are particularly prone to its decomposition. The products of photochemical reactions can affect the efficacy of Tetracaine Hydrochloride. Tetracaine chloride, is a local anesthetic. Photochemical reaction refers to the excitation of photons by molecules in a solution or solid, triggering a chemical reaction. In the photochemical reaction of Tetracaine Hydrochloride molecules, after being excited by photons, spontaneous fracture reactions occur and harmful chemicals are released.
The photochemical reaction of Tetracaine Hydrochloride mainly consists of two parts:
Electron excitation and ultrafast chemical reaction.
Electronic excitation refers to the generation of excited state electrons after molecules absorb photons. The energy absorption of photons by molecules can increase the energy levels of electrons, making them more energetic and chemically reactive. After molecules absorb photons, processes such as spin flipping, resonance energy transfer, and electron transfer can occur, promoting electron excitation and chemical reactions. However, these excited state electrons are prone to fragmentation reaction, producing harmful ions and free radicals, causing serious cell damage.
Ultrafast chemical reaction
Ultrafast chemical reaction refers to the chemical reaction of excited state molecules in a very short time. Tetracaine hydrochloride molecules may undergo similar ultrafast chemical reactions, such as electron transfer, fluorescence resonance energy transfer, etc., after photoexcitation. These reactions can produce harmful substances and cause serious damage to cells. In addition, photochemical reactions may also trigger a series of other reactions, such as redox reactions, free radical chain reactions, etc.
In summary, in the photochemical reaction of tetracaine hcl powder molecules, the molecules excited by photons will undergo spontaneous fracture reactions and release harmful chemicals. These reactions have serious impacts on organisms, including cell damage, organ toxicity, etc. Therefore, when using Tetracaine Hydrochloride, it is necessary to avoid its exposure to light in order to reduce the occurrence of these reactions.
Tetracaine Hcl Powder may interact with other drugs during use, which may affect its efficacy or increase the risk of adverse reactions. The following is a summary of possible interactions with other drugs:
Other local anesthetics
When used in combination with procaine, lidocaine, etc., it may enhance the local anesthetic effect, but at the same time, it may also increase the risk of toxic reactions. Therefore, it is necessary to pay attention to adjusting the dosage during use to avoid excessive use.
Antiarrhythmic
Antiarrhythmic drugs such as amiodarone may affect cardiac conduction and increase the likelihood of arrhythmia when used in combination. Therefore, for patients who need to use both drugs simultaneously, close monitoring of electrocardiogram and other indicators should be carried out to ensure medication safety.
Muscle relaxants
Muscle relaxants such as vecuronium may enhance their muscle relaxation effect when used in combination, leading to adverse reactions such as respiratory depression. Therefore, special attention should be paid to the patient's respiratory condition during use to ensure unobstructed airway.
Sedative-hypnotics
When used in combination with sedatives such as diazepam and phenobarbital, it may enhance central inhibitory effects and increase the risk of drowsiness, coma, and other symptoms. Therefore, for patients who need to use both drugs simultaneously, their consciousness status should be closely monitored to avoid accidents.
Liver enzyme inhibitor
When used in combination with liver enzyme inhibitors such as cimetidine and ketoconazole, it may slow down its metabolism and prolong its duration of action. This may lead to excessive drug efficacy or prolonged duration, increasing the risk of adverse reactions. Therefore, special attention should be paid to the patient's reaction during use and the medication plan should be adjusted in a timely manner.
Sulfonamide drugs
Caution is advised when this substance is used in combination with sulfonamide drugs such as sulfamethoxazole, as the likelihood of allergic reactions may increase. Accordingly, this substance is contraindicated for patients with a known allergy to sulfonamides.
The frequency of monitoring blood pressure in elderly people after use should follow the following guidelines:
During the initial treatment stage, unstable blood pressure, or adjustment of medication treatment plan, it is recommended to measure blood pressure every morning and evening (2-3 times each time, take the average), measure continuously for 7 days, and calculate the average blood pressure after 6 days.
For elderly patients undergoing long-term medication treatment, it is recommended to monitor their blood pressure status before taking medication to evaluate the efficacy of the medication. It is best to self measure sitting blood pressure at a fixed time after waking up in the morning, taking antihypertensive medication, before breakfast, and after urination.
After initiating new drugs or adjusting medication treatment, monthly follow-up evaluations are required to assess compliance and treatment response until the blood pressure is reduced to standard. The follow-up content includes the compliance of blood pressure values, whether there has been orthostatic hypotension, and whether there have been any adverse drug reactions.
For elderly patients with stable blood pressure control, the monitoring frequency can be reduced and blood pressure can be measured only one day a week.
Backed by Blomtechz's rigorous quality system, Tetracaine Hcl Powder delivers consistent high purity and dependable performance across a wide range of medical and pharmaceutical applications.
Case 1 - Surgical Anesthesia
Scenario: Bupivacaine HCl powder is widely used in surgical settings, particularly for nerve block, epidural, and infiltration anesthesia. Its rapid, reliable onset helps reduce patient pain and anxiety during procedures.
Procedure: The powder is dissolved in a suitable solvent to prepare an injectable or spray formulation, applied to the nerves or tissues in the surgical area before the operation begins.
Effect: Doctors achieve smooth, effective local anesthesia, enabling safer procedures with significantly reduced intraoperative pain and more predictable outcomes.
Case 2 - Pain Management
Scenario: For patients with chronic pain requiring long-term management, bupivacaine HCl powder serves as an effective therapeutic foundation.
Procedure: Clinicians develop individualized treatment plans, typically formulating the drug into gels or creams that patients can apply conveniently at home.
Effect: Patients experience meaningful pain relief and a marked improvement in quality of life. When used as directed, the drug offers a favorable, well-documented safety profile - a safe and effective option for ongoing pain management.
The Blomtechz Advantage Beyond the product itself, Blomtechz is built to make sourcing simple and risk-free. Every batch is released with complete quality documentation, including COA, for full traceability and peace of mind. Our professional packaging protects against light, moisture, and contamination - especially critical for light-sensitive APIs - so product integrity is preserved from our warehouse to yours. A stable supply chain and flexible packaging options let you scale from R&D trials to full production without disruption, while responsive technical support is ready to assist with formulation, documentation, or regulatory questions at every step. With experienced global logistics and a dedicated account manager, you get clear communication and on-time delivery from inquiry to final handover.
From the operating room to the production line, bupivacaine hydrochloride powder carries significant clinical value; responsible use, always following professional guidance, keeps it safe and effective. Whatever your application, Blomtechz is the partner that delivers the quality, stability, and service you can build on.
Reference
[1]Lee, H.-S. (2016). Recent advances in topical anesthesia. Journal of Dental Anesthesia and Pain Medicine, 16(4), 237–244.
[2]Hale, S. J. M., Lengyel, O., Louis, D., Kim, R., & Douglas, R. G. (2025). The anaesthetic efficacy of tetracaine and oxymetazoline compared with Co-Phenylcaine in healthy individuals. Clinical Otolaryngology, 50(1), 46–52.
[3]Bai, W., Luo, D., Wurige, M., Xiao, B., & Li, J. (2025). Research on the use of tetracaine hydrochloride jelly surface anesthesia in combination with intravenous anesthesia for pain-free cystoscopy. Frontiers in Medicine, 12, Article 1653269.
[4]Gala, U., Chuong, M. C., Varanasi, R., & Chauhan, H. (2015). Characterization and comparison of lidocaine-tetracaine and lidocaine-camphor eutectic mixtures based on their crystallization and hydrogen-bonding abilities. AAPS PharmSciTech, 16(3), 528–536.
[5]Liu, C., Luo, Y., Tao, Q., Hong, L., & Zeng, S. (2023). Characterization of seven new related impurities and forced degradation products of tetracaine hydrochloride and proposal of degradation pathway by UHPLC-Q-TOF-MS. Journal of Pharmaceutical and Biomedical Analysis, 223, Article 115116.
Frequently Asked Questions
How do I verify the purity and quality before ordering?
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Every batch is tested before release and ships with a Certificate of Analysis (COA) covering assay, related impurities, and key physical properties, with full batch traceability. Request a sample and COA from Blomtechz first - we're happy to let the data do the talking.
Tetracaine HCl is light-sensitive. How do you keep it stable in transit?
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Correct - tetracaine HCl is prone to photodegradation, which is why Blomtechz packages every order in light-resistant, moisture-protective containers and provides clear storage guidance. Product integrity is protected from our warehouse to your production line, so what you receive matches what was tested.
Can we start with a small order for R&D, or is there a minimum?
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Blomtechz offers flexible MOQs - start with gram-level R&D quantities, then scale up seamlessly to bulk production without changing suppliers. One partner from lab trial to commercial batch.
Do you provide documentation for regulatory filing and audits?
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Yes. Blomtechz supplies a complete documentation package - COA, SDS, specification and stability data - and supports regulatory inquiries for your filings. Our technical team is available to answer formulation or compliance questions throughout your project.
What about lead time and long-term supply stability?
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Blomtechz maintains stable inventory and a reliable supply chain, with consistent lead times and volume-based pricing. A dedicated account manager keeps you informed from inquiry to delivery - contact us for current stock and a quote.
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