2-Hydroxy-4-methoxybenzaldehyde CAS 673-22-3
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2-Hydroxy-4-methoxybenzaldehyde CAS 673-22-3

2-Hydroxy-4-methoxybenzaldehyde CAS 673-22-3

Product Code: BM-2-5-401
CAS number: 57-71-6
Molecular formula: C4H7NO2
Molecular weight: 101.1
EINECS number: 200-348-5
MDL No.: MFCD00002116
Hs code: 29280090
Analysis items: HPLC>99.0%, LC-MS
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Changzhou Factory
Technology service: R&D Dept.-4

 

2-Hydroxy-4-methoxybenzaldehyde, also known as 4-methoxysalicylaldehyde, is an important organic chemical substance. Molecular formula C8H8O3, CAS 673-22-3, At room temperature and pressure, it is a white crystalline or colorless crystalline solid. It has a fragrance similar to vanillin and can be used in baked goods, soft drinks, alcoholic beverages, breakfast cereals, chewing gum, icing sugar, frozen dairy products, jelly, pudding, hard candy, instant coffee and tea, dairy products, seasonings, gummies, and sweet sauces to enhance the aroma and taste of food. FEMA (Food Flavor and Extract Manufacturers Association) has specific regulations on its recommended dosage in food to ensure its safety and suitability in food. It can also be used as an intermediate in organic synthesis, participating in various chemical reactions to generate drug molecules with specific pharmacological activities, providing important support for new drug development.

Produnct Introduction

Chemical Formula

C8H8O3

Exact Mass

152

Molecular Weight

152

m/z

152 (100.0%), 153 (8.7%)

Elemental Analysis

C, 63.15; H, 5.30; O, 31.55

CAS 673-22-3 | Shaanxi BLOOM Tech Co., Ltd

2-Hydroxy-4-methoxybenzaldehyde | Shaanxi BLOOM Tech Co., Ltd

Applications

2-Hydroxy-4-methoxybenzaldehyde (HMB) is an important organic compound with multiple uses and a wide range of application examples. The following is a detailed introduction to its purpose and specific application examples:

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

1. Medical field

 

It has significant application value in the field of medicine. Due to its antibacterial, antifungal, anti-inflammatory, antipyretic, chemical protective, liver protective, neuroprotective, and antioxidant properties, it is often used as a pharmaceutical intermediate, providing important support for new drug development.

(1) Liver protection and neuroprotective effects:
It also has liver protection and neuroprotective effects. It can protect the liver from damage and promote the growth and repair of nerve cells.
These characteristics make it potentially valuable for the treatment of hepatitis, cirrhosis, neurodegenerative diseases, and other conditions.

 

(2) Synthesize drug molecules with pharmacological activity:
It can serve as a precursor for synthesizing certain drug molecules with specific pharmacological activities. For example, it can participate in the synthesis of drugs with anti-inflammatory, analgesic, or anti-tumor activity.
In the process of developing new drugs, scientists often use their specific chemical properties to create drug molecules with new pharmacological effects through chemical modification or structural modification.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd
2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

2. Cosmetics field

 

In the field of cosmetics, it also has a wide range of applications. Because of its remarkable whitening effect and good safety performance, it is often used as one of the main ingredients of whitening face cream, whitening essence, whitening facial mask and other cosmetics.
(1) Whitening face cream:
The whitening face cream containing this substance can make the skin brighter and whiter by reducing the production of melanin.
This face cream is usually suitable for all skin types, especially people with dark skin and more spots.

 

(2) Whitening essence:
It can also be added to the whitening essence to deeply affect the skin and inhibit the synthesis of melanin.
At the same time, it can also provide other nutrients such as vitamin C, hyaluronic acid, etc., making the skin smoother and more delicate.
(3) Whitening facial mask:
The whitening facial mask containing this product can quickly replenish moisture and nutrition for the skin, while inhibiting the production of melanin.
After use, the skin will become bright and radiant in a short period of time. This kind of facial mask is usually suitable for occasions where quick whitening or skin tone improvement is required.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd
2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

3. Food additive field

 

With people's increasing attention to food safety and health, the application of food additives in the field is also gradually receiving attention. Because of its vanillin like aroma, it can be used as food essence or flavoring agent to add aroma and taste to food.
(1) Baking food:
Adding an appropriate amount of this substance to baked goods such as cakes, bread, etc. can enhance the aroma and flavor of the food.
This aroma and flavor are usually similar to vanilla, caramel, etc., which can enhance the taste and quality of food.

 

(2) Soft drinks and alcoholic beverages:
It can also be used as a flavoring agent in soft drinks and alcoholic beverages.
It can provide unique aroma and taste to these beverages, making them more delicious.
(3) Other foods:
In addition to the aforementioned foods, it can also be used in various other foods such as breakfast cereals, chewing gum, frosting, frozen dairy products, jelly, pudding, hard candy, instant coffee and tea, dairy products, seasonings, gummies, and sweet sauces (sweet sauces).
In these foods, they can also play a role in adding aroma and taste.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

In addition, it is worth noting that although it has broad application prospects in the field of food additives, its usage and safety also need to be strictly controlled and regulated. FEMA (Food Flavor and Extract Manufacturers Association) has specific regulations on its recommended dosage in food to ensure its safety and suitability in food. At the same time, the Chinese Health Commission has also accepted its application as a new variety of food additive, which may expand its application in the fields of food preservation or flavor enhancement in the future.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

4. Other application areas

 

In addition to the aforementioned fields, it can also be applied to multiple other areas.
(1) Organic synthesis:
As an important intermediate in organic synthesis, it can participate in various organic chemical reactions, such as condensation reactions, esterification reactions, etc.
These reactions can generate organic compounds with specific structures and properties, providing more choices for the field of organic synthesis.

 

(2) Pesticides:
Research has found that it has inhibitory effects on certain crop pests and diseases.
Therefore, it may be used as one of the active ingredients in pesticides for the prevention and control of crop diseases and pests.
(3) Other chemical industries:
In other chemical industries, it can also be used as a raw material or intermediate.
For example, it can be used to synthesize certain chemicals such as dyes, fragrances, or resins.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd
2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

5. Specific application examples

 

Here are some specific application examples about:
(1) Application in pharmaceutical research and development:
A pharmaceutical company has successfully developed a new type of anti-inflammatory drug using it as a synthetic precursor. This drug has significant anti-inflammatory effects and minimal side effects, and can be used clinically to treat diseases such as rheumatoid arthritis and osteoarthritis.

(2) Application in pesticide research and development:
A pesticide company has successfully developed a new type of pesticide using it as one of the active ingredients. This pesticide has a significant inhibitory effect on crop pests and diseases, and is environmentally friendly without causing pollution. In field experiments, the pesticide showed good control effects and provided strong support for agricultural production.

 

(3) Application in cosmetics production:
A cosmetics company launched a whitening essence, whose main ingredients include the ingredients of the product. This essence can deeply affect the skin, inhibit the synthesis of melanin, and provide other nutrients to make the skin more smooth and delicate. After use, consumers generally reported an improvement in skin tone and brighter skin.

(4) Application in the food industry:
A certain food manufacturer adds an appropriate amount of this substance as a seasoning in baked goods. This seasoning can give food a unique aroma and flavor, enhancing the taste and quality of the food. Consumers have expressed that the food has a better taste and is even more delicious after tasting it.

2-Hydroxy-4-methoxybenzaldehyde uses | Shaanxi BLOOM Tech Co., Ltd

2-Hydroxy-4-methoxybenzaldehyde has a wide range of application fields and specific application examples. In the field of medicine, it can serve as a precursor for synthesizing drug molecules with pharmacological activity; In the cosmetics field, it can be used as one of the main ingredients of cosmetics such as whitening face cream, whitening essence and whitening facial mask; In the field of food additives, it can be used as food essence or flavoring agent; In addition, it can also be used in organic synthesis, pesticide research and development, and other chemical industries.

Usage

2-Hydroxy-4-methoxybenzaldehyde (HMB) has a wide range of applications in the pharmaceutical field, and its pharmaceutical mechanism mainly involves the following aspects:

1. Pharmacological activity

2-Hydroxy-4-methoxybenzaldehyde is a reactant in the synthesis of LPA1R antagonists, which can be used to inhibit the proliferation and contraction of normal human lung fibroblasts induced by LPA. In addition, it is also an important raw material for synthesizing tyrosine kinase 6 protease inhibitors. These pharmacological activities make 2-hydroxy-4-methoxybenzaldehyde potentially valuable for drug development.

2. Biological activity and mechanism of action

Antibacterial and antifungal effects:
2-Hydroxy-4-methoxybenzaldehyde has significant antibacterial and antifungal activity, and can inhibit the growth of various bacteria and fungi.
Its mechanism of action may involve damaging the cell wall or membrane of bacteria or fungi, interfering with their metabolic processes, and thus achieving antibacterial or bactericidal effects.
Anti inflammatory and antipyretic effects:
2-Hydroxy-4-methoxybenzaldehyde can inhibit inflammatory reactions and alleviate swelling and pain caused by inflammation.
At the same time, it also has antipyretic effects, which can lower body temperature and alleviate fever symptoms.
Chemical protection, liver protection, neuroprotection:
2-Hydroxy-4-methoxybenzaldehyde can protect cells from chemical damage and has a chemical protective effect.
It can also protect the liver from damage and promote the repair and regeneration of liver cells.
In addition, 2-hydroxy-4-methoxybenzaldehyde also has neuroprotective effects, which can protect nerve cells from damage and improve nerve function.
Antioxidant effect:
2-Hydroxy-4-methoxybenzaldehyde has strong antioxidant activity, which can eliminate free radicals in the body and reduce oxidative stress damage to cells.
This helps to delay aging, prevent diseases, and protect physical health.

3. Application in specific diseases

Respiratory system diseases:
2-Hydroxy-4-methoxybenzaldehyde can be used to treat respiratory diseases such as bronchial asthma, by inhibiting inflammation and relaxing bronchial smooth muscle to alleviate symptoms.
skin disease:
Due to its antibacterial and antifungal effects, 2-hydroxy-4-methoxybenzaldehyde can be used to treat various skin diseases, such as eczema, dermatitis, etc.
Liver disease:
The hepatoprotective effect of 2-hydroxy-4-methoxybenzaldehyde makes it a potential drug for treating liver diseases such as hepatitis and cirrhosis.
Neurological disorders:
Its neuroprotective effect makes 2-hydroxy-4-methoxybenzaldehyde have potential application value in the treatment of neurological diseases, such as Parkinson's disease, Alzheimer's disease, etc.

4. Drug development and clinical application

At present, 2-hydroxy-4-methoxybenzaldehyde has been widely used as a pharmaceutical intermediate. With the in-depth study of its pharmacological and biological activities, more and more drug development is paying attention to this compound. In the future, the application of 2-hydroxy-4-methoxybenzaldehyde in drug development will be more extensive and in-depth, providing new options for the treatment of more diseases.

In summary, 2-hydroxy-4-methoxybenzaldehyde has broad application prospects and potential therapeutic value in the pharmaceutical field. Its pharmacological activity, biological activity, and mechanism of action provide new ideas and methods for the treatment of various diseases.

Frequently Asked Questions
 

What is 4 Methoxybenzaldehyde used for?

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4-Methoxybenzaldehyde is widely utilized in research focused on: Fragrance and Flavor Industry: This compound is commonly used as a key ingredient in perfumes and flavorings due to its pleasant aromatic properties, enhancing the sensory experience of various products.

What is the common name for 2-hydroxybenzaldehyde?

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Salicylaldehyde. Salicylic aldehyde (2-hydroxybenzaldehyde) is an organic compound with the formula C 6H 4OH(CHO). Along with 3-hydroxybenzaldehyde and 4-hydroxybenzaldehyde, it is one of the three isomers of hydroxybenzaldehyde.

What chemical smells like vanilla?

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Vanillin.

What is the most toxic aldehyde?

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The major toxic aldehydes identified include acrolein, acetaldehyde, formaldehyde, t,t-2,4-decadienal (t,t-2,4-DDE), 4-hydroxy-2-hexenal (4-HHE), and 4-hydroxynonenal (4-HNE), which have been associated with adverse health effects ranging from respiratory irritation to carcinogenicity.

What foods contain benzaldehyde?

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Benzaldehyde is naturally found in almonds, apples, peaches, cherry and apricot kernels, and other Prunus species (fruits that have pits).

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