Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of hydroxypropyl methylcelluloase(hpmc) cas 9004-65-3 in China. Welcome to wholesale bulk high quality hydroxypropyl methylcelluloase(hpmc) cas 9004-65-3 for sale here from our factory. Good service and reasonable price are available.
Hydroxypropyl methylcellulose (HPMC), also known as HPMC, is a white fibrous or granular powder. Soluble in water and some solvents, such as ethanol/water and propanol/water in proper proportion. The aqueous solution has surface activity. High transparency and stable performance. The gel temperature of products of different specifications is different, and the solubility changes with viscosity. The lower the viscosity, the greater the solubility. The performance of HPMC of different specifications is different, and the dissolution of HPMC in water is not affected by pH value.
With the decrease of methoxy content, the increase of gel point, the decrease of water solubility and the decrease of surface activity of HPMC. HPMC also has the characteristics of thickening ability, salt resistance, low ash powder, pH stability, water retention, dimensional stability, excellent film-forming property, and extensive enzyme resistance, dispersibility and cohesiveness. It is one of the non-ionic cellulose mixed ethers. It is a semi synthetic, inactive, viscoelastic polymer, often used in ophthalmology as a lubricant, or as an excipient or excipient in oral medicine.
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Chemical Formula |
C3H7O |
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Exact Mass |
59 |
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Molecular Weight |
59 |
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m/z |
59 (100.0%), 60 (3.2%) |
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Elemental Analysis |
C, 60.98; H, 11.94; O, 27.08 |
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Hydroxypropyl Methylcelluloase(HPMC) is used as thickener, dispersant, binder, excipient, oil resistant coating, filler, emulsifier and stabilizer in the textile industry. It is also widely used in synthetic resin, petrochemical industry, ceramics, paper making, leather, medicine, food, cosmetics and other industries.
Main purpose：
1. Construction industry: As a water retaining agent and retarder of cement mortar, the mortar has pumping property. Plaster mortar, gypsum material, putty powder or other building materials as the adhesive to improve the smearability and prolong the operation time. It can be used to paste ceramic tile, marble, plastic decoration, paste reinforcing agent, and reduce cement consumption. The water retention property of HPMC makes the slurry not crack due to too fast drying after application, and enhances the strength after hardening.
2. Ceramic manufacturing industry: widely used as adhesive in ceramic product manufacturing.
3. Paint industry: As a thickener, dispersant and stabilizer in the paint industry, it has good compatibility in water or organic solvents. As a paint remover.
4. Ink printing: As a thickener, dispersant and stabilizer in the ink industry, it has good compatibility in water or organic solvents.
5. Plastic: used as mold release agent, softener, lubricant, etc.
6. PVC: used as dispersant in PVC production, it is the main auxiliary agent for suspension polymerization to prepare PVC.
7. Pharmaceutical industry: coating materials; Membrane material; Controlled speed polymer material of sustained release preparation; Stabilizer; Suspension aids; Tablet adhesive; Tackifier
8. Others: It is also widely used in leather, paper products, fruit and vegetable preservation and textile industries.
Chemical industry:
1. Polymerization of vinyl chloride and vinylidene: As a stabilizer and dispersant during polymerization, it can be used together with polyvinyl alcohol (PVA) hydroxypropyl cellulose (HPC) to control particle shape and particle distribution.
2. Adhesive: As the adhesive of wallpaper, it can be used together with vinyl acetate latex paint instead of starch.
3. Pesticide: added to pesticides and herbicides to improve the adhesion effect during spraying.
4. Latex: emulsion stabilizer for improving asphalt emulsion, thickener for styrene butadiene rubber (SBR) latex.
food industry
1. Canned citrus: prevents yellowing and spoilage caused by the decomposition of citrus glycosides during storage, thus achieving a preservation effect.
2. Cold fruit products: added to fruit juice, ice, etc. to enhance the taste.
3. Seasoning sauce: used as an emulsifying stabilizer or thickener for seasoning sauce and tomato sauce.
4. Cold water coating and polishing: Used for frozen fish storage, it can prevent discoloration and quality degradation. After coating and polishing with methyl cellulose or hydroxypropyl methyl cellulose aqueous solution, freeze it on an ice layer.
5. Adhesive for tablets: As a molding adhesive for tablets and granules, it has good adhesive properties at the time of bonding (quickly dissolves, collapses, and disperses when taken).
Construction industry:
1. Cement mortar: improve the dispersion of cement sand, greatly improve the plasticity and water retention of mortar, have an effect on preventing cracks, and enhance the cement strength.
2. Ceramic tile cement: improve the plasticity and water retention of pressed ceramic tile mortar, improve the adhesive strength of ceramic tiles, and prevent pulverization.
3. Coating of asbestos and other refractory materials: as a suspension safety agent, a mobility improver, it can also improve the adhesive strength to the substrate.
4. Gypsum concrete slurry: improve the water retention and processability, and improve the adhesion to the substrate.
5. Joint cement: added to the joint cement used for gypsum board to improve the fluidity and water retention.
6. Latex putty: improve the fluidity and water retention of resin latex based putty.
7. Plaster: As a substitute for the paste of natural materials, it can improve the water retention and improve the adhesive strength of the same substrate.
8. Paint: As a plasticizer of latex paint, it can improve the operability and fluidity of paint and putty powder.
9. Spraying paint: it has good effect on preventing the cement system or latex system spraying materials from sinking and improving the fluidity and spray pattern.
10. Secondary products of cement and gypsum: used as extrusion molding adhesive for hydraulic substances such as cement asbestos system to improve fluidity and obtain uniform molded products.
11. Fiber wall: It is effective as the adhesive of sand wall due to its anti enzyme and anti bacteria effects.
12. Others: It can be used as thin cement sand mortar and air bubble retention agent for mud hydraulic operators.
Pharmaceutical industry
1. Coating: the coating agent is made into a solution of organic solvent or an aqueous solution and given to tablets, especially the particles made are spray coated.
2. Slow release agent: With a dosage of 2-3 grams per day and 1-2 grams per time, the effect will be observed in 4-5 days.
3. Eye drops: Due to the osmotic pressure of hydroxypropyl methylcellulose aqueous solution being the same as that of tears, it is less irritating to the eyes.
Hydroxypropyl Methylcelluloase(HPMC) is added to eye drops as a lubricant for contact with the intraocular lens.
4. Jelly: Used as a base material for gel like topical medications or ointments.
5. Impregnating agent: used as a thickener and water retaining agent.
6. Jelly like: Used as a jelly like matrix for topical medicine or ointment.
Other industries
1. Fiber: Used as a printing dye paste for pigments, boron earth forest dyes, salt based dyes, textile dyes. In addition, it can be used in conjunction with thermosetting resins in the corrugated processing of kapok.
2. Paper: Used for gluing and oil resistant processing on the surface of carbon paper.
3. Leather: Used as a final lubricant or disposable adhesive.
4. Water based ink: added to water-based ink and ink as a thickener and film-forming agent.
5. Tobacco: As a binder for regenerating tobacco.
Kiln industry
1. Electronic materials: As a binder for the extrusion molding of ceramic electric density devices and ferrite alumina magnets, it can be used in combination with 1.2propanediol.
2. Glaze: Used as a glaze for ceramics and in combination with enamel, it can improve adhesion and processability.
3. Refractory mortar: added to refractory brick mortar or casting furnace materials, it can improve plasticity and water retention.
The synthesis process of hydroxypropyl methyl cellulose is a sophisticated and multi-step chemical reaction process. Firstly, high-quality cotton cellulose is selected as the starting material and placed in an alkaline solution, which usually uses sodium hydroxide. The temperature is controlled between 35 and 40 degrees Celsius, and the processing time lasts for half an hour. This step aims to open some hydrogen bonds in the cellulose molecular chain through alkalization treatment, preparing for subsequent reactions.
After processing, excess alkali solution is removed by pressing, and then the cellulose is crushed to ensure uniform particle size, which is beneficial for the subsequent reaction to proceed uniformly. Next, appropriate aging treatment is carried out at 35 degrees Celsius, which is crucial for stabilizing the structure of alkali fibers and ensuring that the average polymerization degree of the obtained alkali fibers meets the requirements for the subsequent synthesis of hydroxypropyl methyl cellulose.
Entering the etherification stage, the pre treated alkali fibers are transferred to a dedicated etherification reactor. Under strictly controlled conditions, epoxy propane is first added, followed by chloromethane. These two compounds will react with hydroxyl groups on cellulose molecules, introducing hydroxypropyl and methyl groups, respectively. The reaction temperature should be maintained between 50 and 80 degrees Celsius, and etherification should be continued for 5 hours. During this period, the maximum pressure in the system should be controlled at about 1.8 megapascals to ensure efficient and safe reaction.
After the etherification reaction is completed, the product needs to undergo a series of post-treatment steps. Firstly, add an appropriate amount of hydrochloric acid and oxalic acid to hot water at 90 degrees Celsius for washing. This step not only helps neutralize the remaining alkali, but also promotes the volume expansion of the product for subsequent processing. Subsequently, the material is efficiently dehydrated using a centrifuge and washed multiple times until the washing solution becomes neutral, ensuring that no harmful chemicals remain in the product.
When the moisture content of the material drops below 60%, Hydroxypropyl Methylcelluloase(HPMC) enters the drying stage. Drying the material with a hot air flow at 130 degrees Celsius until the moisture content drops below 5% is crucial for the stability and storage performance of the final product. Finally, the dried material is crushed and sieved through a 20 mesh sieve to ensure uniform particle size and meet application requirements. At this point, the synthesis process of hydroxypropyl methyl cellulose is completed, and the resulting product can be used in pharmaceuticals, food, cosmetics, and multiple industrial fields, demonstrating a wide range of application prospects.
FAQ
What is hydroxypropyl methylcellulose used for?
Description. Hydroxypropyl methylcellulose belongs to the group of medicines known as artificial tears. It is used to relieve dryness and irritation caused by reduced tear flow. It helps prevent damage to the eye in certain eye diseases.
Is hydroxypropyl methylcellulose good or bad for you?
Although the FDA has approved methylcellulose for consumption, it's best to have it in moderation, or even not at all. Your body isn't used to highly processed foods and compounds, so a high intake can easily lead to unwanted inflammation as your body tries to fight off the unrecognized nutrients.
Is hydroxypropyl methylcellulose a natural ingredient?
It is a synthetic substance derived from cellulose, which is often found in plant-based sources. HPMC's primary functions in cosmetic products include moisturizing, stabilizing, and improving texture.
Is methylcellulose safe to take daily?
Is there any harm in taking a fiber supplement every day? Taking fiber supplements every day seems to be safe. Popular fiber supplements include inulin, psyllium (Metamucil, Konsyl, others) and methylcellulose (Citrucel). Fiber is good for the body.
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