Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of melanotan 2 powder cas 121062-08-6 in China. Welcome to wholesale bulk high quality melanotan 2 powder cas 121062-08-6 for sale here from our factory. Good service and reasonable price are available.
Melanotan 2 Powder is a synthetic melanocortin receptor agonist. It is an injectable polypeptide hormone that promotes tanning. Melanotan, CAS 121062-08-6, generally white solid powder. The molecular weight may be related to its amino acid sequence and degree of cyclization. Generally speaking, the molecular weight of peptides ranges from thousands to tens of thousands. It has good water solubility and fat solubility. During the synthesis process, solvents such as N, N-dimethylformamide (DMF), pyridine, tetrahydrofuran (THF), and ether need to be used for the reaction. It is a synthetic melanocortin receptor agonist. It is an injectable peptide hormone that can promote tanning. We have melanotan ii peptide for sale. If you need to buy melanotan ii online, please contact our sales representative.
We set an business example here:
|
|
|
Physical & chemical properties
Solubility
H2O: 5 mg/mL, soluble. Also methanol and ethyl acetate, but its solubility is poor in non-polar solvents
Acidity coefficient (pKa)
13.00±0.70(Predicted)
Stability
It is relatively stable at room temperature, but will decompose under high temperature, light, acid and alkaline conditions
Water solubility
Soluble to 0.70 mg/ml in water
 |
 |
Melanotan Ii COA
01.How long does delivery to Poland take?
02.Is payment in advance?
- clear product info, specifications and qty
- quotation
- pay
- ship
- after service
03.Is it possible to produce GHK CU but at a dose of 20 mg/vial? Bpc 10mg? Is it possible to change the amount of the substance?
04.I would like to ask for photos of the products, what do the vials you produce look like?
05.At what quantity can I count on discounts?
Melanotan II, also known as MT-II, is a synthetic peptide hormone analog that has gained popularity in recent years for its potential applications in skin tanning and sexual enhancement. This peptide stimulates the production of melanin, the pigment that gives skin its color, resulting in a darker, more bronzed appearance.
One of the primary applications of Melanotan II is in the field of cosmetology. Many individuals seek to achieve a deeper, more natural-looking tan without the need for excessive sun exposure or the use of artificial tanning products. Melanotan II can help achieve this by promoting melanin production in the skin, allowing users to develop a tan with less exposure to UV rays.
In addition to its cosmetic uses, Melanotan II has also been explored for potential sexual enhancement effects. Some studies have suggested that the peptide may have a stimulatory effect on libido and sexual arousal. However, it's important to note that these effects are not fully understood or widely accepted, and further research is needed to confirm any sexual enhancement benefits.
Melanotan 2 powder researched by: BLOOM TECH
Remark: BLOOM TECH(Since 2008), ACHIEVE CHEM-TECH is the subsidiary of us.
Melanotan 2 Powder, also known as α- Melanocyte stimulating hormone is an endogenous peptide with strong melanocyte stimulating hormone activity. Under normal physiological conditions, it mainly regulates the hypothalamic pituitary adrenal axis, binds to and activates the melanocyte stimulating hormone receptor subtype MC1R, causing melanocytes to produce melanin. However, if laboratory synthesis methods are used to manually prepare Melanotan, the following steps are required:
Material preparation
Amino acids
The amino acids required for synthesizing Melanotan include tryptophan, histidine, lysine, methionine, leucine α- Aminobutyric acid, aspartic acid, phenylalanine, serine, arginine, proline, valine, isoleucine, alanine, and glycine. These amino acids need to be provided in powder or crystalline form and purified before synthesis.
Solvent
The synthesis of Melanotan requires the use of solvents such as N, N-dimethylformamide (DMF), pyridine, tetrahydrofuran (THF), and ether.
Reagents
The synthesis of Melanotan also requires some chemical reagents, such as sodium hydroxide, sodium hydride hydrochloride, lithium aluminum hydride hydrochloride, ethylene glycol, etc.
Solid phase peptide synthesizer
This instrument can automatically complete the peptide synthesis process, including steps such as amino acid condensation, deprotection, and cleaning.
Synthesis steps
Add the required amino acids in the synthesis order to the solid-phase peptide synthesizer, and set the instrument temperature to 40 ℃. Then add an appropriate amount of diisopropylethyl chloromethane (DIPEA) and N, N-dimethylformamide (DMF) solvent to begin the condensation reaction. This reaction requires stirring and protection with nitrogen gas.
After the condensation reaction is completed, a deprotection reaction is required. Add an appropriate amount of trifluoroacetic acid and dimethyl formamide (DMF) solvent and reduce the temperature to below 0 ℃. Then add an appropriate amount of sodium hydroxide aqueous solution to complete the deprotection reaction.
After the deprotection reaction is completed, a cleaning reaction is required. Add an appropriate amount of water for washing, and then add an appropriate amount of ether for cleaning. Finally, add an appropriate amount of pyridine for drying.
After the cleaning reaction is completed, add the required amino acids in the synthesis order to the cyclization reaction bottle. Add an appropriate amount of N, N-dimethylformamide (DMF) solvent and reduce the temperature to below 0 ℃. Then add an appropriate amount of lithium aluminum hydride hydrochloride and ethylene glycol solution to complete the cyclization reaction.
After the cyclization reaction is completed, a purification reaction is required. Filter the supernatant and wash the precipitate with an appropriate amount of ether. Then dissolve the precipitate in an appropriate amount of water and add an appropriate amount of ion exchange column for purification treatment. Finally, freeze-drying was performed to obtain high-purity Melanotan solid powder.
The above are the basic steps for synthesizing Melanotan. The chemical reagents and operations involved in these steps require strict quality control and safety measures, which need to be carried out under professional laboratory conditions. Therefore, it is recommended to conduct synthesis experiments in professional research institutions or laboratories of pharmaceutical companies.
Frontiers of Neural Control
Neurocontrol is the process by which the nervous system regulates physiological functions of the body through signaling molecules such as neurotransmitters and hormones. Melanotan 2 powder, as a melanocortin receptor agonist, can bind to various melanocortin receptors (MC receptors) and regulate the function of the nervous system. In recent years, with the continuous deepening of neuroscience research, its application in the field of neural control has gradually attracted attention. Its unique physiological activity and extensive mechanism of action provide new ideas for neuroscience research and clinical applications.
Melanotan 2 has demonstrated potential application value in the field of neural regeneration. Animal experiments have shown that Melanotan 2 powder can promote the regeneration and repair of peripheral nerves. For example, in a rat sciatic nerve injury model, Melanotan 2 significantly enhanced the recovery of sensory function, especially at specific doses (such as 20 μ g/kg/48h). This effect may be related to the promotion of neuronal survival, axonal growth, and synapse formation by Melanotan 2. The regulatory effect of Melanotan 2 on sexual function is another important application area. Research has shown that Melanotan 2 can enhance sexual desire and arousal by activating MC3R and MC4R receptors. In men with erectile dysfunction (ED), Melanotan 2 has been shown to be an effective erectile promoter, capable of promoting erection through dose-dependent induction. This effect may be related to Melanotan 2 promoting smooth muscle relaxation in the corpus cavernosum and increasing penile blood flow.
Applications at the forefront of neural control
Erectile dysfunction is one of the common sexual dysfunctions in men, which seriously affects the quality of life of patients. Melanotan 2 can improve erectile dysfunction by activating MC receptors, especially MC4R receptors. Animal experiments have shown that intravenous injection of Melanotan 2 (such as 1 mg/kg) significantly enhances the erectile response caused by cavernous nerve stimulation. In addition, Melanotan 2 can shorten the latency period of the first erection event, increase the frequency and duration of erections. The regulatory effect of Melanotan 2 on appetite and energy balance is also one of its important physiological functions. Research has shown that Melanotan 2 can reduce body weight by activating MC4R receptors, suppressing appetite, and decreasing food intake. In the mouse model, Melanotan 2 also induced thermogenic reactions and increased energy expenditure. This effect may be related to Melanotan 2 regulating the hypothalamic appetite regulation center and promoting fat breakdown.
Multiple animal experiments have shown that Melanotan 2 has significant effects in the field of neural control. For example, in a rat sciatic nerve injury model, Melanotan 2 significantly enhanced the recovery of sensory function. In addition, Melanotan 2 has shown good therapeutic effects in animal models of erectile dysfunction. These experimental evidences provide strong support for the application of Melanotan 2 in the field of neural control. Although Melanotan 2 has not been officially approved for human treatment in most countries and regions, some clinical trials have preliminarily explored its potential applications in the field of neural control. For example, in patients with erectile dysfunction, Melanotan 2 has been shown to significantly improve erectile function and enhance the quality of sexual life. However, due to the insufficient evaluation of the safety and long-term efficacy of Melanotan 2, its clinical application still requires caution.
Hot Tags: Melanotan 2 Powder CAS 121062-08-6, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, dermorphin peptide, DERMORPHIN, Melanotan ii powder, dermorphin in humans, Cosmetic