Oat Peptide

Its role in the field of intestinal health is comprehensive.
Firstly, regulate the gut microbiota. As a prebiotic analogue, it can significantly promote the proliferation of beneficial bacteria such as bifidobacteria and lactobacilli, while inhibiting the growth of harmful bacteria and maintaining the balance of intestinal microbiota. Clinical observation data shows that after continuous intake of oat for 4 weeks, the diversity of gut microbiota in healthy adults increased by 15%, and the improvement rate of constipation symptoms was as high as 62%.

Secondly, enhance the intestinal barrier function. It can stimulate the repair of intestinal mucosal cells, enhance the integrity of the intestinal barrier, reduce the leakage of harmful substances into the bloodstream through the intestinal wall, and fundamentally reduce the risk of systemic inflammation.
Thirdly, promote digestion and defecation. The dietary fiber in it can promote intestinal peristalsis, help eliminate metabolic waste and microbial toxins accumulated in the intestine, and alleviate digestive discomfort such as constipation or diarrhea.

This series of effects make oat an ideal choice for individuals with suboptimal gut health.

Loyal guardians of the cardiovascular system
The protective effect on cardiovascular system is one of the most fully studied fields at present, involving three dimensions of blood pressure reduction, lipid reduction and anti atherosclerosis.

1. Lowering blood pressure
Can effectively inhibit the activity of angiotensin-converting enzyme (ACE). ACE promotes the conversion of angiotensin I into angiotensin II, which has a strong vasoconstrictive effect, leading to an increase in blood pressure. Inhibition of ACE is like installing a controller on the "valve" that raises blood pressure, keeping blood vessels in a moderately relaxed state.
The research on Beiyan oats further revealed the molecular mechanism of oat peptides in lowering blood pressure:

Mainly by reducing the levels of endothelin (ET-1), tumor necrosis factor - α (TNF - α), renin (Renin), and angiotensin II (ANG II), while increasing the levels of bradykinin (BK) and nitric oxide (NO), thus exerting the effect of lowering blood pressure. It is worth emphasizing that the blood pressure lowering process of oat is smooth and does not cause blood pressure fluctuations caused by medication. It has a significant effect on hypertensive patients, especially those with primary hypertension, but has no antihypertensive effect on those with normal blood pressure, making it extremely safe.

Oat alkaloids (AVAs) exert synergistic effects through another pathway:

on the one hand, they inhibit the phosphorylation level of retinoblastoma proteins by upregulating the p53/p21cip pathway; On the other hand, it can inhibit the proliferation of smooth muscle cells, increase the production of nitric oxide, significantly increase the expression of lipoprotein lipase (LPL) mRNA, increase the hydrolysis of triglycerides in plasma lipoproteins, and prevent atherosclerosis.

2. Lowering Blood Lipids
It exerts lipid-lowering effects through two channels: firstly, inhibiting the absorption of cholesterol in the intestine and setting up special "checkpoints" on the intestinal "transport channel";

Secondly, it promotes the conversion of cholesterol into bile acids for excretion from the body, further reducing blood cholesterol levels.
Animal experimental data shows that feeding high-fat feed while supplementing oat reduces serum total cholesterol by 18% and low-density lipoprotein cholesterol (LDL-C) by 23%, without reducing the beneficial high-density lipoprotein cholesterol (HDL-C) for the human body. The β - glucan and active peptides in it can effectively inhibit the deposition of cholesterol in the blood vessel wall, reduce the risk of arteriosclerosis, and are particularly suitable for people with high blood pressure, high blood pressure, and high blood pressure.

3. Anti atherosclerosis
Oat alkaloids (AVAs) can reduce the expression of adhesion molecules (ICAM-1, VCAM-1 and E-selectin) in endothelial cells, reduce the secretion of proinflammatory cytokines IL-6, chemokine IL-8 and monocyte chemoattractant protein (MCP-1), and significantly reduce the progression of atherosclerosis through anti-inflammatory effect.
Meanwhile, its antioxidant properties can neutralize free radicals in the body and protect the integrity of vascular endothelial cells. A complete and healthy endothelial cell can maintain the normal dilation and contraction function of blood vessels, ensuring smooth blood flow.

It are rich in polyphenols and amino acid residues, and their antioxidant capacity is comparable to vitamin E. They can eliminate free radicals in the body and reduce oxidative stress damage to cells.
In terms of skin anti-aging, it has three functions: firstly, moisturizing - its hydrophilicity can adsorb and lock in surface moisture of the skin, improving dryness and roughness of the skin;

Secondly, antioxidant - rich sulfur amino acids act as antioxidants, reducing the production of free radicals and protecting the skin from oxidative damage; Thirdly, promote repair - accelerate epidermal cell renewal and wound healing, reduce scar formation.
This internal antioxidant ability not only delays skin aging, but also reduces the risk of chronic inflammation, making it known as an "oral anti-aging agent".

The small molecule peptides can be directly absorbed by the intestine, quickly enter the bloodstream, and be transported to the required parts of the human body, continuing to maintain biological activity in the body and directly participating in and regulating important life activities. Its immune regulatory mechanism includes promoting immunoglobulin synthesis, enhancing macrophage activity, and accelerating the synthesis of immune proteins in the human body. For people who are prone to colds, have recovered after surgery, or have weakened immunity, oat peptides can effectively enhance the body's defense capabilities.

In terms of sugar control: By inhibiting the activity of alpha amylase, slowing down the breakdown and absorption of carbohydrates, it helps stabilize postprandial blood sugar levels. At the same time, it can promote the secretion of glucagon like peptide-1 (GLP-1) and enhance insulin sensitivity, which is particularly beneficial to people in pre diabetes. Low glycemic index (GI value only 25), can be used as a staple food to replace some carbohydrates.

In terms of weight management: high dietary fiber content can slow down gastric emptying, prolong satiety, and reduce calorie intake. Both animal and human experiments have confirmed that peptides can accelerate subcutaneous fat reduction, and the amount of fat reduction increases with increasing peptide intake. In the treatment of childhood obesity patients, a low calorie diet supplemented with peptides is more effective in accelerating subcutaneous fat reduction and promoting an increase in basal metabolic levels than a simple low calorie diet.

This is the most breakthrough direction in oat research in recent years.
Research has found that AVN-C is the only substance present in oats among existing grains, which can effectively inhibit protein formation that triggers dementia. The research team has applied for patents in the United States, Europe, and China, and published relevant papers in international academic journals.
The protective mechanisms against Alzheimer's disease include:
Reduce the expression of A β 1-42: Control the production of "junk proteins" in the brain from the source and improve the microenvironment of brain cells;

Promote the expression of neurotrophic factors: increase the quantity and activity of neurotransmitters, enhance neuronal nutrition and vitality;
Regulating synaptic plasticity: providing possibilities for repairing damaged and aging neuronal cells;
Antioxidant protection: protects brain neurons from free radical damage;
Activation and repair of brain cells: The peptide content in the elderly decreases, and peptide supplementation is of great significance for activating brain cells.

At the external level, the skin benefits of oat peptides have been widely recognized:
Moisturizing: Hydrophilic adsorption and locking in moisture, improving dryness and roughness;
Antioxidant: Sulfur amino acids reduce free radicals and delay photoaging;
Promote repair: accelerate epidermal cell renewal and reduce scar formation.