Methoxypolyethylene Glycol CAS 9004-74-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of methoxypolyethylene glycol cas 9004-74-4 in China. Welcome to wholesale bulk high quality methoxypolyethylene glycol cas 9004-74-4 for sale here from our factory. Good service and reasonable price are available.

Methoxypolyethylene glycol, colorless liquid, with a water solubility of 50mg/mL at 25 ° C. It is used in building materials industry as raw material of cement superplasticizer and reinforcer. It is stable under normal temperature and pressure. The polycarboxylic acid superplasticizer synthesized with this raw material has a strong ability to maintain the dispersion of cement particles, so that the product has the advantages of low dosage, high water reduction rate, good reinforcement effect, durability, non rusting reinforcement and environmental friendliness.

Usage of Methoxypolyethylene Glycol：

1. It can be used in commercial concrete with high performance and high strength (above C60) that is mixed on site and transported over a long distance.

2. Polyethylene glycol monomethyl ether is soluble in water, ethanol and organic solvents. Low steam pressure, heat stable, used as thickener and lubricant in textile printing and dyeing industry and daily chemical industry.

3. Polyethylene glycol monomethyl ether has good water solubility, wettability, lubricity, physiological inertia, no irritation to human body, and is mild. It is widely used in cosmetics and pharmaceutical industry. Products with different molecular weight fractions can be selected to change the viscosity, hygroscopicity and structure of the products. The products with low relative molecular weight (molecular weight less than 2000) are suitable for use as wetting agents and consistency regulators, such as cream, lotion, toothpaste and shaving cream. Products with high relative molecular weight are suitable for lipstick, deodorant stick, soap, shaving soap, foundation make-up, beauty cosmetics, etc. In cleaning agent, it is also used as suspending agent and thickening agent.

4. In the pharmaceutical industry, it is used as the matrix of ointment, emulsion, ointment, lotion and suppository.

5. It also reacts with acrylic acid to make MPEG acrylic acid ester, which is the main raw material for preparing polycarboxylate superplasticizer.

Methoxypolyethylene Glycol Synthesis method:

It belongs to the technical field of synthesis of ether compounds in organic chemistry. First, wash the reactor with a low boiling point solvent as the kettle washing solution for 1~5 times, and then take methanol, ethylene glycol methyl ether, diethylene glycol methyl ether, triethylene glycol methyl ether, etc. as the initial initiator to react with ethylene oxide in the presence of a catalyst to obtain polyethylene glycol monomethyl ether. Its low boiling point solvent is any of methanol, ethanol, propanol, etc; The catalyst is either solid sodium methoxide, sodium methoxide methanol solution, KOH, NaOH, etc.

The invention uses methanol, methanol and methanol Solvents with low boiling point such as ethanol and propanol and good compatibility with water are kettle washing liquid, solid sodium methoxide or sodium methoxide methanol solution, KOH, NaOH, etc. are catalysts, and methanol, ethylene glycol monomethyl ether, diethylene glycol monomethyl ether, triethylene glycol monomethyl ether are initial initiators. The process is reasonable and the reaction activity is high, which can effectively reduce the content of polyethylene glycol (PEG) in polyethylene glycol monomethyl ether.

With the rapid development of Methoxypolyethylene glycol, surfactant and other fields, and under the background of continuing to vigorously develop fine chemicals in China, the domestic demand for ethylene glycol, synthetic detergent, ethylene oxide derived surfactant and other products will continue to increase, especially in the development and application of new products, ethylene oxide market still has great potential, which will form an effective support for the rising price of ethylene oxide. The market space of ethylene oxide derived special chemicals such as Methoxypolyethylene glycol is very broad in China.

As the country maintains growth and expands domestic demand, a series of economic stimulus policies and industrial revitalization plans are gradually showing their boosting effects. Following the approval of the Ministry of Railways' 2 trillion yuan railway investment plan by the State Council, the transportation department is preparing a 5 trillion yuan investment plan. The 5 trillion yuan investment, including projects under construction, planned projects and additional investment, will involve the construction of roads, waterways, ports and docks. In particular, the planned investment of provincial and municipal high-speed passenger dedicated lines has undoubtedly played a great role in boosting the demand for additives, and Methoxypolyethylene glycol, as the raw material of additives, will also benefit from it. Among the downstream products of polyethylene glycol monomethyl ether, the water reducer is one of the important products in the pillar industry of new building materials, and the naphthalene superplasticizer is the most widely used in China. However, it has become a trend to be replaced by polycarboxylic acid type water reducer, and polycarboxylic acid type water reducer will become more and more popular in the Chinese market; In terms of pharmaceuticals, China will surpass Spain to become the seventh largest pharmaceutical market in the world in 2009; In terms of cosmetics, the market volume of China's cosmetics will reach about 80 billion yuan by 2010. It is estimated that the equivalent consumption of ethylene oxide in China will reach 6.8 million tons by 2012, and the equivalent production capacity of ethylene oxide will be only about 3.8 million tons at that time. The production is insufficient and the development and utilization prospects are broad. At that time, the total production capacity of Methoxypolyethylene glycol in China will also reach about 4.2 million tons.

● Moisturizers and Emollients

mPEG is widely used in skincare products for its ability to retain moisture. It forms a hydrating film on the skin, preventing water loss and improving texture. For example:

Lotions and Creams: mPEG-2000 is incorporated into formulations to enhance spreadability and hydration.

Hair Care Products: It acts as a conditioner, reducing frizz and improving combability.

● Surfactants and Emulsifiers

mPEG derivatives, such as PEG-40 hydrogenated castor oil, are used as non-ionic surfactants in cleansers and shampoos. They stabilize oil-in-water emulsions, ensuring uniform distribution of active ingredients.

● Sunscreens

mPEG improves the solubility of UV filters in sunscreen formulations, enabling higher SPF values and better skin adherence.

● Anti-Aging Products

By reducing transepidermal water loss (TEWL), mPEG helps maintain skin elasticity, making it a key ingredient in anti-aging creams.

● Drug Delivery Systems

PEGylation: The covalent attachment of mPEG to therapeutic proteins (e.g., enzymes, antibodies) or nanoparticles enhances solubility, reduces immunogenicity, and prolongs circulation half-life. PEGylated drugs like Adagen® (pegademase bovine) and Oncaspar® (pegaspargase) exemplify this approach.

Liposomes and Micelles: mPEG-coated liposomes (stealth liposomes) evade immune clearance, improving drug delivery to tumors. Doxil®, a PEGylated liposomal doxorubicin, is FDA-approved for ovarian cancer and Kaposi's sarcoma.

● Protein and Peptide Modification

Reduced Immunogenicity: PEGylation masks antigenic epitopes, reducing antibody formation. This is critical for long-term therapies like interferon-α-2b (PegIntron®).

Enhanced Stability: mPEG protects proteins from proteolytic degradation and thermal denaturation.

● Tissue Engineering and Regenerative Medicine

Hydrogels: mPEG-based hydrogels are used for cell encapsulation and drug release. Their tunable mechanical properties and biocompatibility make them ideal for wound healing and cartilage repair.

3D Printing: mPEG derivatives are incorporated into bioinks for 3D-printed scaffolds, supporting cell growth and tissue regeneration.

● Medical Devices

Coatings: mPEG coatings on implants (e.g., stents, catheters) reduce thrombogenicity and bacterial adhesion, lowering infection risks.

Hot Tags: methoxypolyethylene glycol cas 9004-74-4, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, melamine powder, propylene oxide market, tris base powder, N N Dimethylformamide pure, 37 formaldehyde, Basic Chemicals