N,N-Dimethylaniline CAS 121-69-7

1. Core raw materials for basic and alkaline dyes
It is the basic raw material for producing triphenylmethane dyes (such as alkaline purple 5BN, alkaline green) and azo dyes (such as alkaline light yellow, bright red 5GN). Taking alkaline tender yellow O (C.I. alkaline yellow 2) as an example, its synthesis requires coupling reaction with diazonium salt of p-aminobenzenesulfonic acid to ultimately generate dye molecules with high color intensity and strong light resistance. This type of dye is widely used for dyeing textile fibers such as cotton, linen, and silk, as well as for coloring paper and leather, with an annual demand accounting for over 15% of the global dye market.

1. Synthesis of antibiotics and sulfonamide drugs
It is a key intermediate of cephalosporin V. During the synthesis process, its methyl amino group is introduced into the cephalosporin nucleus through nucleophilic substitution reaction, forming an antibiotic molecule with a β - lactam ring structure, which increases the inhibitory activity against Gram positive bacteria by 50%. In addition, it is also used to synthesize sulfonamide drugs such as sulfamethoxazole, which exert antibacterial effects by blocking the bacterial folate metabolism pathway, with a clinical cure rate of over 85%.

2. Research and development of anti-tumor and antiviral drugs
In the synthesis of Flucytosine, as a catalyst, it promotes the fluorination reaction of the pyrimidine ring, increasing the purity of the product from 90% to 98% and significantly reducing drug side effects. Its derivative 4-amino-N, N-dimethylaniline can also be used to synthesize the anti-tumor drug Mitoxantrone. It can inhibit the proliferation of tumor cells by embedding double strands of DNA, with an effective rate of 60% for breast cancer and lymphoma.

1. Intermediate of fungicides and herbicides
N,N-Dimethylaniline is the core intermediate of fungicides such as Dexon. Dikesong effectively prevents and treats crop root rot and Fusarium wilt by inhibiting the respiratory chain enzyme activity of pathogenic bacteria, with a clinical prevention and control effect of over 90%. In addition, its derivatives can be used to synthesize the herbicide 2,4-D (2,4-dichlorophenoxyacetic acid). By simulating the interference of plant growth hormone on weed growth, the killing rate of broad-leaved weeds can reach 95%, and it is environmentally friendly.
2. Synthesis of insect pheromones and attractants
N. Derivatives of N-dimethylaniline (such as N, N-dimethyl-1-naphthylamine) can serve as precursors for insect pheromones, used for synthesizing sex attractants, trapping agricultural pests (such as cotton bollworms and corn borers), reducing the use of chemical pesticides by more than 30%, and promoting the development of green agriculture.

1. High performance solvents and extractants
Due to its high boiling point (193.1 ℃) and good solubility, it is used as a solvent for paints and inks, as well as a carrier for metal preservatives. For example, in ship anti rust paint, it can dissolve anti rust pigments such as zinc powder and zinc phosphate to form a uniform coating, extending the anti-corrosion life to more than 10 years.
2. Intermediate of explosives and propellants
Can be used as an intermediate for synthesizing explosives such as TNT (trinitrotoluene). By introducing nitro groups through nitration reaction, 2,4,6-trinitro-N, N-dimethylaniline is generated, which can be further reduced to obtain TNT with an explosive energy density of 3500 kJ/kg. It is widely used in military and mining fields.