Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 3-aminophenylboronic acid pinacol ester cas 210907-84-9 in China. Welcome to wholesale bulk high quality 3-aminophenylboronic acid pinacol ester cas 210907-84-9 for sale here from our factory. Good service and reasonable price are available.
3-Aminophenylboronic acid pinacol ester is an organic compound with the molecular formula C12H18BNO2, CAS 210907-84-9, and a relative molecular weight of 225.09 g/mol. It is a solid state, usually in the form of white or similar white granular crystals. It may also be a white or similar white powder. It has a certain solubility in common organic solvents, such as dichloromethane, chloroform, ethanol, methanol, etc. It can dissolve in most polar solvents, but its solubility is lower in non-polar solvents. Relatively stable under conventional storage conditions, but contact with oxygen, moisture in the air, and strong oxidants should be avoided. The crystal structure can be analyzed by methods such as X-ray diffraction. By analyzing the crystal structure, the molecular arrangement and spatial geometric configuration of the compound can be understood. Under high temperature conditions, decomposition or loss of crystalline water may occur. The thermal decomposition temperature and thermal stability depend on factors such as experimental conditions and purity. Commonly used as a reagent, ligand, or intermediate in chemical synthesis. It can participate in various organic synthesis reactions, such as boric acid coupling reaction, Suzuki Miyaura cross coupling reaction, etc. These reactions have wide applications in the preparation of drugs, pesticides, and functional molecules.
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C.F |
C12H9Br |
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E.M |
223 |
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M.W |
233 |
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m/z |
232 (100.0%), 234 (97.3%), 233 (13.0%), 235 (12.6%) |
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E.A |
C, 61.83; H, 3.89; Br, 34.28 |
There are multiple positions in the 3-Aminophenylboronic acid pinacol ester molecule that can form hydrogen bonds. The following are some possible positions for hydrogen bond formation:
1. Hydrogen bonds on amino groups:
The amino group (NH2) in the 3-Aminophenylboronic acid pinacol ester molecule has hydrogen atoms that can form hydrogen bonds with appropriate receptor or donor molecules. Hydrogen atoms on amino groups can form hydrogen bonds with molecules with electronegative atoms such as oxygen, nitrogen, or fluorine. The formation of this hydrogen bond can be achieved through the interaction between free hydrogen in the amino group and atoms with higher electron density.
2. Hydrogen bonding on hydroxyl groups:
The hydroxyl group (OH) on the pinacol group can also form hydrogen bonds. The hydrogen on this hydroxyl group can form hydrogen bonds with atoms with lone pair electrons such as oxygen or sulfur.
3. Hydrogen bonding of ester groups:
The hydrogen atom (H) in the ester group can also participate in the formation of hydrogen bonds. For example, it can form hydrogen bonds with oxygen or nitrogen atoms in ligands or other molecules.
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Some common uses of 3-Aminophenylboronic acid pinacol ester in drug research and development:
1. Drug molecular design:
3-aminophenylboronic acid piperone ester, as an intermediate in organic synthesis, is often used in drug research to design and synthesize new drug molecules. By introducing different functional groups into its structure, its biological activity, solubility, and stability can be changed, thereby optimizing the performance of drugs.
2. Drug screening: The use of a compound library composed of 3-aminophenylborate piperone ester and its derivatives for high-throughput screening (HTS) is an important step in drug development. By evaluating the interactions between these compounds and specific targets, candidate compounds with potential pharmacological effects can be screened.
3. Pharmacodynamic evaluation: 3-Aminophenylboronic acid piperone ester can be used in drug research to evaluate the efficacy and side effects of drugs. By studying its binding ability and selectivity with specific targets, the mechanism of action and potential clinical applications of drug molecules in vivo can be evaluated.
4. Drug delivery system: 3-aminophenylborate piperone ester can combine with carrier materials to form a drug delivery system, which is used to enhance the solubility, stability, and targeting of drugs. By controlling the release rate and action location of drugs in the body, the effectiveness of drug treatment can be improved and side effects can be reduced.
5. Tumor treatment: 3-aminophenylborate piperone ester can be used for the design and synthesis of anti-tumor drugs. For example, it can be introduced into small molecule compounds to inhibit the growth and spread of cancer cells. In addition, it can also be combined with targeted ligands to achieve selective targeted therapy of tumor tissue.
6. Anti-inflammatory drugs: 3-aminophenylborate piperone ester has good anti-inflammatory activity and can be used to develop and optimize anti-inflammatory drugs. By regulating the inflammatory signaling pathway and immune response, the symptoms of inflammatory diseases and the production of inflammatory mediators can be alleviated.
7. Immunomodulators: In the field of immunotherapy, 3-aminophenylboronic acid piperone ester can be used as an immune modulator. By regulating the activity and balance of the immune system, it can enhance the immune response, suppress autoimmune diseases, and regulate organ transplant rejection.
8. Anti infective drugs: 3-aminophenylborate piperone ester and its derivatives also have potential applications in the research of anti infective drugs. By interfering with the metabolic pathways of microorganisms or targeting specific infection related proteins, new antibacterial or antiviral drugs can be developed.
Scope of sales channels
3-Aminophenylboronic acid pinacol ester (CAS 210907-84-9) is an important organic boronic acid compound, which contains boronic acid groups protected by amino groups, benzene rings, and pinacol esters in its chemical structure. This compound is widely used in the fields of pharmaceutical intermediates, organic synthesis, materials science, and life sciences due to its unique chemical properties. It plays an irreplaceable role in drug development (such as anticancer drugs, antibacterial agents), coupling reaction catalysts, and polymer material modification. The following is a detailed analysis of its sales channel scope:
Sales channel type
Direct sales channel: direct connection between manufacturers and end users
Direct sales channels are one of the core sales models for 3-amino-phenylboronic acid pinal ester, especially suitable for long-term cooperation between large manufacturers and end users (such as pharmaceutical companies and research institutions). Manufacturers can customize product purity (such as 98%, 99%), packaging specifications (such as 1g, 5g, 25g, 100g, 1kg, etc.) according to customer needs, and provide technical documentation (such as MSDS, COA) and application support. After eliminating intermediate links, the terminal price is 10% -20% lower than that of traders, especially suitable for long-term procurement contracts. Manufacturers can ensure the stability of raw material supply and cost control through vertical integration, such as building their own production lines for synthesizing pinal esters.
Traders and Agents: Deep Cultivation and Coverage of Regional Markets
Traders and agents are important bridges connecting manufacturers and end-users, especially suitable for small and medium-sized customers and regional markets. Traders usually set up warehousing and logistics centers in key areas such as the Yangtze River Delta and Pearl River Delta, supporting small batch purchases (such as a minimum order of 1g) and quick response (such as 1-3 days for shipping). In addition to product sales, some traders also provide technical consultation, joint research and development, and after-sales service to enhance customer stickiness. By representing products from multiple manufacturers, traders can reduce the supply risk of a single supplier.
E-commerce Platform: An Emerging Force in Digital Sales
E-commerce platforms have simplified the procurement process through digital means, especially suitable for small and medium-sized customers and emergency procurement needs. The platform centrally displays product information from multiple suppliers, such as purity, price, and inventory, and supports horizontal comparison. The online inquiry, ordering, and payment functions significantly shorten the procurement cycle, and some platforms provide "one click procurement" services. Platforms typically provide logistics tracking, quality feedback, and after-sales support to reduce procurement risks.
International Market Channels: Export Trade and Localized Services
The international market is an important growth point for the sales of 3-amino-phenylboronic acid pinal ester, especially suitable for markets in Europe, America, India, and Southeast Asia. Manufacturers or large traders export their products directly to overseas customers through customs declaration, suitable for pharmaceutical intermediate customers with strict quality requirements. Reselling through foreign trade companies or local agents is suitable for enterprises lacking international market experience. Set up warehouses or offices in the target market to provide localized technical support and after-sales service.
Regional distribution of sales channels
The international sales channels for 3-amino-phenylboronic acid pinal ester are mainly export trade, with target markets including Europe, America, India, Southeast Asia, and other regions. Manufacturers or traders export 3-aminophenylboronic acid pinacol ester to overseas customers through customs declaration. Reselling through foreign trade companies or agents is suitable for enterprises lacking international market experience.
- European and American markets require extremely high purity (≥ 99%), mainly used for the synthesis of pharmaceutical intermediates and high-end materials.
- Indian market: mainly price sensitive demand, 3-amino-phenylboronic acid pinal ester is used for the synthesis of generic drug raw materials.
- Southeast Asian market: rapidly growing demand, mainly used in the fields of pesticides, dyes, and functional materials.
Matching customer needs with sales channels
Research institutions and universities
Small dosage (milligrams to grams), high purity (≥ 98%), and flexible requirements (such as sudden experimental needs).
Pharmaceutical companies
Large dosage (from gram level to kilogram level), strict purity requirements (≥ 99%), and the need to provide compliance documents (such as COA and MSDS).
Materials Science Enterprise
Moderate dosage (gram to kilogram level), focus on cost-effectiveness, and require technical support (such as application process optimization).
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