Isopropylbenzylamine hydrochloride, alias N-benzylisopropylamine, CAS No. 102-97-6, molecular formula C10H16N, colorless to yellow oily liquid, is a commonly used organic base and an essential organic synthesis Raw materials are widely used intermediates or drug precursors in the pharmaceutical industry. They are used primarily in organic intermediates and rust inhibitors. They are irritating and avoid direct contact. They are chemical intermediates. The standard form is N-isopropyl benzylamine salt, a pure white crystal. Since N-isopropyl benzylamine and methamphetamine are isomers, have the same molecular weight, and are secondary amines, N-isopropyl benzylamine and methamphetamine have a similar appearance and melting point physical properties. The system's pH was controlled to take advantage of the difference in alkalinity constant, Kh, between benzisopropylbenzylamine hydrochloride and isopropyl benzylamine hydrochloride. In the method of the present invention, both bases are weak. Methamphetamine is a tertiary amine, and methamphetamine is a secondary amine. The literature shows that the K values of tertiary and secondary amines differ by 2. Propylbenzylamine is partitioned into the organic phase and benzisopropylbenzylamine hydrochloride into the aqueous phase. This operation is carried out at ambient temperature and pressure. The only equipment requirements are a suitable container and a suitable agitator. Optionally, the process of the present invention can be carried out in a reactor to prepare benzisopropylbenzylamine hydrochloride.
Isopropylbenzylamine hydrochloride has no irritating or stimulant effects, and its toxicity is unknown. Only a few countries have researched N-isopropyl benzylamine, usually stored in a calm and ventilated warehouse. Keep away from fire and heat sources. Should be kept away from oxidizer, do not store together. They are equipped with the appropriate variety and quantity of fire equipment. Storage areas should be equipped with emergency release equipment and suitable containment materials. The substance is slightly hazardous to water. Avoid contact with potent oxidizing agents.
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Density(g/mL,25/4℃) | 0.895 |
Boiling point(ºC, normal pressure) | 200 |
Refractive index | 1.5020 |
Flashpoint (ºC) | 87 |
Traits | Colorless to the yellow oily liquid |
Molar volume (m3/mol) | 164.4 |
Isotonic specific volume (90.2K) | 388.7 |
Surface tension (dyne/cm) | 31.2 |

