Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of matrixyl 3000 cream in China. Welcome to wholesale bulk high quality matrixyl 3000 cream for sale here from our factory. Good service and reasonable price are available.
Matrixyl 3000 Cream is a topical anti-aging and restorative cream formulated with a blend of palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 as its core active ingredients. The product focuses on gently regulating the skin's extracellular matrix and soothing chronic microinflammation, making it suitable for daily care of young-to-mature skin as well as for maintaining the skin barrier at home following aesthetic procedures.Bloomtechz leverages its mature R&D system, comprehensive quality reports, and one-on-one technical support to provide customers with a stable supply of raw materials.
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Matrixyl 3000 COA
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| Certificate of Analysis | ||
| Compound name | Matrixyl 3000 | |
| Grade | Pharmaceutical grade | |
| CAS No. | N/A | |
| Quantity | 19g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090055 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure | N/A | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.50% |
| Loss on drying | ≤1.0% | 0.68% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.45% |
| Single impurity | <0.8% | 0.78% |
| Total microbial count | ≤750cfu/g | 98 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 570ppm |
| Storage | Store in cool, dark place or refrigerator | |
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The selection of excipients in the formulation system is critical to the quality of the final product. The oil phase, aqueous phase, emulsification system, and antioxidant components must be compatible with the active peptides and must not cause degradation of the peptide chains. In terms of commercial ingredient supply, Bloomtechz possesses mature capabilities in Matrixyl 3000 Cream formulation development and ingredient supply. Positioned as a manufacturer of functional peptide ingredients and finished product formulation solutions, the company operates an independent R&D laboratory and provides clients with comprehensive quality reports, formulation optimization, and one-on-one technical consulting services.
Bloomtechz assists brands in completing formulation prototyping, stability assessments, and the organization of compliance documentation, ensuring accurate active ingredient ratios and batch consistency.It is primarily targeted at four key areas: at-home skincare, post-professional treatment home maintenance, long-term care for sensitive and early-aging skin, and OEM/ODM formulation development for skincare products. This cream is for topical application only; it must not be injected and should only be applied to intact skin surfaces. It must not be used on broken or eroded skin.Post-aesthetic procedure home care is another key application scenario.
After aesthetic procedures such as photorejuvenation, microneedling, or chemical peels, once the surface wounds have completely healed, this cream can be used to aid in recovery. By leveraging the anti-inflammatory properties of peptides combined with the occlusive moisturizing effects of the cream base, it strengthens the skin barrier and reduces the likelihood of recurring post-procedure dryness and redness. Please note: Do not apply the cream while the skin has open wounds to avoid the risk of irritation from the formulation's ingredients.
Formulations require slight adjustments for different skin types: versions for oily skin should reduce the proportion of heavy oils to prevent clogging;
versions for dry skin should increase the proportion of occlusive oils and moisturizing polyols; and versions for sensitive skin should minimize potentially irritating excipients such as fragrances and colorants.Bloomtechz's exceptional sales team, drawing on feedback from the market and retail end-users, can provide partner clients with skin-type-specific formulation optimization recommendations and one-on-one service. This includes raw material selection, emulsification system guidance, and warnings about ingredient incompatibilities. Leveraging mature technical support, we assist clients in bringing their products to market while helping them avoid common formulation pitfalls.
The core peptide components of Matrixyl 3000 Cream have undergone extensive in vitro testing and human patch tests, and the risk of sensitization is low. However, since the cream is a multi-component formulation, emulsifiers, preservatives, fragrances, and oil-based excipients may all potentially trigger adverse reactions; thus, adverse reactions do not stem solely from the active peptides themselves. Overall, adverse reactions are primarily localized and transient, with severe systemic reactions occurring extremely rarely.
Common mild reactions include:First, a small number of individuals with highly sensitive skin may experience temporary redness or mild itching after initial use.
These reactions are often related to skin tolerance or excipients and typically subside on their own within a few hours to a few days after discontinuing use; Second, for some individuals with oily or acne-prone skin, if the formulation's oils are too occlusive, they may experience a worsening of acne or an increase in closed comedones. This is a matter of formulation compatibility and is not due to the toxicity of the peptides themselves; Third, a very small number of individuals may experience contact allergy, manifested as persistent erythema or papules. In such cases, use should be discontinued immediately, and dermatological intervention should be sought if necessary.
This product is a topical formulation. Due to the large molecular weight of the peptides, they rarely enter the bloodstream under normal application conditions, and there are no reported cases of systemic toxicity. However, the following contraindications must be clearly stated: Do not use on broken, eroded, or exudative skin, or during acute flare-ups of dermatitis; do not apply inside the eyes; use only on the skin's surface. To mitigate risks, we recommend that manufacturers include a note in the product instructions advising first-time users to perform a patch test behind the ear or on the lower jaw. After observing no adverse reactions for 24–48 hours, the product may be applied to the entire face.
Matrixyl 3000 Cream is a cream-based cosmetic product. The core objectives of its packaging design are to protect the product from light and oxygen, prevent microbial contamination, and minimize the oxidation and degradation of peptides, while also balancing the consumer experience with commercial display requirements. On the market, packaging is primarily divided into two categories: finished product packaging for end consumers and bulk raw material packaging for industrial use.
Finished product packaging for end consumers typically consists of opaque wide-mouth cream jars and opaque vacuum pump bottles.
Wide-mouth jars are cost-effective, but each time the lid is opened, the contents are exposed to oxygen and microorganisms from the hands, which can accelerate oxidation and bacterial contamination.Vacuum pump bottles minimize air backflow, making them more effective at maintaining product stability and thus the preferred option for peptide creams. The bottle material is typically opaque plastic or aluminum oxide to avoid the risk of accelerated degradation caused by light exposure associated with transparent glass bottles. The outer packaging is printed with regulatory information, including the product name, ingredient list, net content, lot number, production date, expiration date, storage conditions, and manufacturing details.
It is a cosmetic product. Unlike injectable formulations, it does not undergo terminal high-temperature sterilization, as high temperatures would directly destroy the activity of the peptides. The comprehensive sterilization and preservation system consists of three layers of protection: raw material sterilization, cleanroom control during production, and the preservative system within the formulation.
First, raw material pretreatment and sterilization. Purified water, which has undergone multiple filtration steps, is used for the aqueous phase; oils and aqueous peptide solutions undergo microbial testing upon arrival at the facility; liquid peptide raw materials can be treated with low-temperature precision filtration to remove microorganisms,
but high-temperature sterilization must not be used.Second, disinfection of the production environment and equipment. Production areas comply with Cosmetics GMP cleanliness requirements and undergo regular air disinfection; production equipment, piping, and storage tanks are cleaned and disinfected via CIP (Clean-in-Place); equipment chambers are disinfected prior to loading; and operators adhere to cleanroom operating procedures to minimize the risk of introducing microorganisms during the production process.
Third, the preservative system within the formulation. Creams are oil-in-water emulsion systems that are highly susceptible to bacterial and fungal growth,
so they must incorporate a compliant cosmetic preservative system.The selection of preservatives must balance antimicrobial efficacy with the need to avoid accelerating the oxidative degradation of peptides-this was a key challenge in the formulation development of the product.
Important note: Relying on high-temperature sterilization of the finished product is not an option. Once the cream is filled, it must not undergo autoclaving or irradiation sterilization, as irradiation may damage peptide molecules. The product's preservative efficacy must be achieved through the formulation's preservative system, and preservative challenge tests must be conducted to validate its effectiveness.
During the formulation development phase, Bloomtechz conducts preservative challenge tests to screen for preservative combinations compatible with peptides and avoid conflicts between preservatives and active ingredients. With the support of proven technology, we can explain the logic behind sterilization and disinfection to our clients, clarify the differences between cosmetic and injectable-grade products in this regard, and provide one-on-one service to help clients avoid process pitfalls such as "attempting high-temperature sterilization, which leads to peptide inactivation."
Matrixyl 3000 Cream is a cosmetic product.Unlike injectable formulations,
it does not undergo terminal high-temperature sterilization, as high temperatures would directly destroy the activity of the peptides. The comprehensive sterilization and preservation system consists of three layers of protection: raw material sterilization, cleanroom control during production, and the preservative system within the formulation.
First, raw material pretreatment and sterilization. Purified water, which has undergone multiple filtration steps, is used in the aqueous phase; oils and aqueous peptide solutions undergo microbial testing upon arrival at the facility; liquid peptide raw materials can be treated with low-temperature precision filtration to remove microorganisms, but high-temperature sterilization must not be used.
Second, disinfection of the production environment and equipment. Production areas comply with Cosmetics GMP cleanliness requirements and undergo regular air disinfection; production equipment, piping, and storage tanks are cleaned and disinfected via CIP (Clean-in-Place); equipment chambers are disinfected prior to loading; and operators adhere to cleanroom operating procedures to minimize the risk of introducing microorganisms during the production process.
Third, the preservative system within the formulation. Creams are oil-in-water emulsion systems that are highly susceptible to bacterial and fungal growth, so they must incorporate a compliant cosmetic preservative system.
The selection of preservatives must balance antimicrobial efficacy with the need to avoid accelerating the oxidative degradation of peptides-this was a key challenge in the formulation development of the product.
Important note: Relying on high-temperature sterilization of the finished product is not an option. Once the cream is filled, it is not subjected to autoclaving or irradiation sterilization, as irradiation may damage peptide molecules. The product's preservative efficacy relies entirely on the formulation's preservative system and must be validated through preservative challenge testing.During the formulation development phase, Bloomtechz conducts preservative challenge tests to screen for preservative combinations compatible with peptides and avoid conflicts between preservatives and active ingredients.
With the support of proven technology, we can explain the logic behind sterilization and disinfection to our clients, clarify the differences between cosmetic and injectable-grade products in this regard, and provide one-on-one service to help clients avoid process pitfalls such as "attempting high-temperature sterilization, which leads to peptide inactivation."
Reference
[1] Pavlova L, Andreeva S, Dimitrova V. Clinical efficacy and tolerance of topical palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7 cream for facial skin aging[J].
[2] Kim J H, Park S Y. Anti-inflammatory and skin-barrier-repairing properties of signal peptides in topical cosmetic formulations[J].
[3] Lintner K, Peschard O. Biological activity of palmitoylated peptides used in anti-aging cosmetic creams: in-vitro and ex-vivo evaluation[J].
[4] Gore C, Martin A. Comparative assessment of anti-aging biomimetic peptides in topical cream formulations: Matrixyl 3000, hexapeptide-8 and GHK-Cu[J].
[5] Johnson W, Burnett C L, Bergfeld W F, et al. Safety assessment of tripeptide-1, hexapeptide-12, their metal salts and fatty acyl derivatives, and palmitoyl tetrapeptide-7 as used in cosmetics[J].
FAQ
Q1: What is the key difference between Matrixyl 3000 Cream and Matrixyl 3000 Serum?
A: Serums are typically water-based formulations with a light, thin texture; the cream uses a water-in-oil emulsion base, which provides stronger moisture retention and allows the peptides to remain on the skin's surface longer. However, due to the limitations of the stratum corneum barrier, the transdermal penetration depth of both formulations is limited, and they both provide gradual improvement. Bloomtechz can provide raw material selection for both formulations, complete quality reports, and one-on-one service.
Q2: Does it cause dependency, and is it suitable for sensitive skin?
A: Peptides are signaling active ingredients; they are hormone-free and do not cause skin dependency. Discontinuing use will not accelerate aging. Peptides themselves have a low probability of causing sensitization; most risks stem from excipients such as emulsifiers and preservatives. For sensitive skin, we recommend conducting a patch test first; do not use if the skin is broken. Bloomtechz can assist customers in streamlining formulation excipients to reduce the risk of sensitization in the finished product and provide proven technical support.
Q3: What are the key precautions for storing the product?
A: Store in a sealed container at 2–25°C, protected from light. Avoid high temperatures, direct sunlight, and repeated freezing and thawing, as these can accelerate the oxidation and degradation of the peptides. Prioritize oxygen- and light-blocking packaging; use the product as soon as possible after opening to minimize exposure to oxygen and microorganisms. Bloomtechz can provide customers with packaging selection recommendations, stability test data, and one-on-one guidance on storage and transportation.
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