Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of afoxolaner tablets in China. Welcome to wholesale bulk high quality afoxolaner tablets for sale here from our factory. Good service and reasonable price are available.
Afoxolaner tablets (trade names such as NexGard and NexGard Spectra) ® Afoxolane is a new type of oral deworming drug for dogs, mainly composed of oxazolines. This drug plays an important role in the field of pet deworming, and has received widespread attention for its high efficiency, safety, and convenience.
(1) Common name and product name:
The generic name for Afrana tablets is Afrana Chewable Tablets, and common product names include NexGard and NexGard Spectra ®) Wait. Aflana tablets with different product names may also contain other ingredients, such as Mirberoxime in addition to Aflana.

(2) Main components:
The main component is Aflana, which has a unique chemical structure and contains an isoxazoline ring core. Through specific substituent modifications, it is endowed with unique biological activity. Aflana acts on ligand gated chloride ion channels, particularly by inhibiting the neurotransmitter gamma aminobutyric acid (GABA) gated channels, thereby blocking the transmission of chloride ions from the presynaptic membrane to the postsynaptic membrane, leading to increased neuronal activity and insect death due to excessive excitation.
(3) Characteristics:
Afurana tablets are usually light red to reddish brown round or square tablets. Tablets of different specificatios may have slight differences in shape and color, for example, Nissin chewable tablets have different specificatios. Specification 1 is a round tablet with 11.3mg, while Specification 2 (28.3mg), Specification 3 (68mg), and Specification 4 (136mg) are square tablets.
Our product



| Price List of Afoxolaner, CAS 1093861-60-9 | |||||||
| The Basic information | Price list | ||||||
| Name | CAS | Category | Specification (Content/PCS) |
Qty (Unit:Board) (Remark:3 PCS/board) |
Unit Price (EXW,USD$/Unit) |
Total Price (EXW,USD$) |
Remark MOQ: 35 Boards, 105 PCS |
| Afoxolaner | 1093861-60-9 | Tablet | 11.3mg (For 2kg-4kg dog) |
35 | $12 | $408 | 105 PCS |
| 100 | $8 | $765 | 300 PCS | ||||
| 500 | $5 | $2,500 | 1500 PCS | ||||
| 28.3mg (For 4kg-10kg dog) |
35 | $12 | $425 | 105 PCS | |||
| 100 | $8 | $808 | 300 PCS | ||||
| 500 | $5 | $2,720 | 1500 PCS | ||||
| 68mg (For 10kg-25kg dog) |
35 | $13 | $450 | 105 PCS | |||
| 100 | $9 | $882 | 300 PCS | ||||
| 500 | $6 | $3,088 | 1500 PCS | ||||
| 136mg (For 20kg-50kg dog) |
35 | $14 | $479 | 105 PCS | |||
| 100 | $10 | $970 | 300 PCS | ||||
| 500 | $7 | $3,529 | 1500 PCS | ||||
Usage and dosage
Administer by weight:
The usage and dosage of Aflana tablets are usually determined based on the weight of the dog. For example, the usage and dosage of Nicosin chewable tablets are as follows:
Dogs weighing 2-4kg should use one 11.3mg chewable tablet.
Dogs weighing 4.1-10kg should use one 28.3mg chewable tablet.
Dogs weighing 10.1-25kg should use one 68mg chewable tablet.
Dogs weighing 25.1-50kg should use one 136mg chewable tablet.
Dogs weighing over 50kg can use a combination of chewable tablets to administer doses within the range of 2.7-6.9mg/kg body weight.
There are also different combinations of specificatios for the highly reliable (Aflanamir Beixime Chewable Tablets), and the appropriate specificatios are selected for administration based on the weight of the dog to ensure that the dosage is within the range of 2.7mg/kg-7.0mg/kg body weight.
Medication frequency:
According to the local epidemiological situation, medication should be administered once a month during the flea and/or tick epidemic season. For scabies mite infection, the medication should be administered once a month, twice in a row. Based on clinical evaluation and skin scraping, the administration time can be extended; For demodex infection, medication should be given once a month until two negative skin smears are obtained every other month. In severe cases, the medication time can be extended.
Administration method:
Afurana tablets are chewable and can be fed directly to dogs. If the dog refuses to consume this product directly, it can be mixed with dog food for administration. After taking out the required number of chewable tablets, please return the remaining tablets to their original packaging; Please wash your hands after using this product.

Additional information of chemical compound:
| Product Name | Afoxolaner Tablet | Afoxolaner Powder |
| Product Type | Tablet | Powder |
| Product Purity | ≥99% | ≥99% |
| Product Specifications | Customizable | Customizable |
| Product Package | Customizable |
Customizable |
Afoxolaner +. COA
![]() |
||
Certificate of Analysis |
||
|
Compound name |
Afoxolaner | |
|
CAS No. |
1093861-60-9 | |
|
Grade |
Pharmaceutical grade | |
|
Quantity |
Customized | |
|
Packaging standard |
Customized | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
|
Lot No. |
20250109001 |
|
|
MFG |
Jan 12th 2025 |
|
|
EXP |
Jan 8th 2029 |
|
|
Structure |
|
|
| TEST STANDARD | GB/T24768-2009 Industry. Stnndard | |
|
Item |
Enterprise standard |
Analysis result |
|
Appearance |
White or almost white powder |
Conformed |
|
Water content |
≤4.5% |
0.30% |
| Loss on drying |
≤1.0% |
0.15% |
|
Heavy Metals |
Pb≤0.5ppm |
N.D. |
|
As≤0.5ppm |
N.D. | |
|
Hg≤0.5ppm |
N.D. | |
|
Cd≤0.5ppm |
N.D. | |
|
Purity (HPLC) |
≥99.0% |
99.5% |
|
Single impurity |
<0.8% |
0.48% |
|
Residue on ignition |
<0.20% |
0.064% |
|
Total microbial count |
≤750cfu/g |
80 |
|
E. Coli |
≤2MPN/g |
N.D. |
|
Salmonella |
N.D. | N.D. |
|
Ethanol (by GC) |
≤5000ppm |
400ppm |
|
Storage |
Store in a sealed, dark and dry place at-20 degrees |
|
|
|
||

Afoxolaner tablets is an isoxazoline compound widely used in the field of pet deworming. Its formulated products (such as Nissin, Super Nissin, etc.) have significant therapeutic effects on various parasitic infections in dogs.
Flea infection
(1) Common flea species
Afurana is mainly used to treat flea infections in dogs. Common flea species include cat flea and dog flea. These two types of fleas are more common in the living environment of dogs. They parasitize on the surface of dogs and feed on their blood.
(2) The hazards of flea infection
Flea infection can bring many hazards to dogs. Firstly, flea bites on a dog's skin can cause itching, causing the dog to constantly scratch and resulting in skin damage, which can easily lead to bacterial infections. Secondly, some dogs are allergic to flea saliva and may experience allergic reactions such as skin redness, swelling, and hair loss.
In addition, fleas are also a vector of tapeworm disease. When dogs lick flea contaminated hair, they may ingest fleas containing tapeworm larvae, thereby infecting tapeworms.
(3) The therapeutic effect of Afurana
Afurana has a rapid killing effect on fleas. After dogs take Afurana orally, the drug can kill fleas within 8 hours. Its mechanism of action is by binding to the neurotransmitter gamma aminobutyric acid (GABA) receptors in fleas, blocking chloride ion channels, causing excessive neuronal excitation, and ultimately leading to flea paralysis and death. Regular use of Afurana can effectively control flea infections in dogs and reduce the harm of fleas to dogs.
Tick infection
(1) Common tick species
Afurana can treat various tick infections in dogs. Common tick species include reticulated tick, castor tick, hexagonal tick, and hemochromatid tick. These ticks usually live in environments such as grass and forests, and dogs are prone to infection during outdoor activities.
(2) The therapeutic effect of Afurana
Afurana has a good killing effect on ticks. After oral administration of Afurana to dogs, the drug can kill ticks within 48 hours. Its mechanism of action is similar to its effect on fleas, by interfering with the tick's nervous system, leading to paralysis and death of the tick. Administering Aflana once a month can effectively prevent and treat tick infections in dogs, reducing the risk of dog infection with related diseases.
(3) The hazards of tick infection
Tick infection poses a great threat to the health of dogs. After ticks bite the skin of dogs, they will insert their mouthparts into the skin and feed on the dog's blood, causing symptoms such as anemia and malnutrition. At the same time, ticks are also vectors of various diseases, such as Lyme disease, Babesiosis, and so on. Lyme disease can cause symptoms such as fever, joint pain, and claudication in dogs, and in severe cases, it can affect the dog's nervous system and heart function; Babesiosis can cause hemolytic anemia in dogs, leading to symptoms such as jaundice and weakness, and even endangering their lives.
Mite infection
(1) Common types of mites
Some formulations containing Afranana (such as Super Trust) can also be used to treat mite infections in dogs. Common types of mites include canine scabies mites and canine demodex mites. The canine scabies mite mainly parasitizes the epidermal layer of dogs' skin, causing scabies mite disease in dogs; Demodex mainly parasitizes in the hair follicles and sebaceous glands of dogs, causing demodex disease in dogs.
(2) The hazards of mite infection
Canine scabies mite infection can cause severe itching in dogs, with symptoms such as redness, papules, and blisters on the skin. Dogs will constantly scratch due to itching, resulting in skin damage, scabbing, and in severe cases, skin infection and hair loss.
Canine demodex infection may not have obvious symptoms in the early stages, but as the condition progresses, the dog's skin may show symptoms such as redness, depilation, increased dandruff, and may also develop secondary bacterial infections, causing pyoderma.
(3) The therapeutic effect of Afurana
Afurana has a certain therapeutic effect on canine scabies mite and canine demodex mite infections. For scabies mite infection, the medication should be administered once a month, twice in a row. Based on clinical evaluation and skin scraping, the administration time can be extended; For demodex infection, medication should be given once a month until two negative skin smears are obtained every other month. In severe cases, the medication time can be extended. Afurana can treat mite infections by interfering with the nervous system of mites, inhibiting their growth and reproduction.
Heartworm and gastrointestinal nematode infections (some products)
1. Heartworm infection
(1) The harm of heartworms
Heartworm is a nematode that parasitizes the heart and pulmonary arteries of dogs. Dogs infected with Heartworm may experience symptoms such as difficulty breathing, coughing, heart failure, and in severe cases, can be life-threatening. Heartworm infection is more common during the season when mosquitoes are active. After mosquitoes bite dogs infected with Heartworm, they will carry Heartworm larvae, which will be transmitted to other dogs when they bite them again.
(2) The preventive effect of Afurana
Products containing Aflana such as Super Reliable (Aflana Milbeixime Chewable Tablets) can be used to prevent canine heartworm infection. Its mechanism of action may be by interfering with the nervous system of heartworm larvae, preventing their development and reproduction in dogs. Regular use of this product can effectively reduce the risk of canine heartworm infection.
2. Gastrointestinal nematode infection
(1) Types and hazards of gastrointestinal nematodes
Gastrointestinal nematodes are a type of nematode that parasitizes the gastrointestinal tract of dogs, including common species such as roundworms, hookworms, and whipworms. These nematodes can take away nutrients from dogs, causing symptoms such as malnutrition, emaciation, and anemia. At the same time, some gastrointestinal nematodes also secrete toxins that affect the digestive function and immune system of dogs.
(2) The therapeutic effect of Afurana
Highly reliable products containing afoxolaner tablets can also be used to treat gastrointestinal nematode infections in dogs. Afurana can act on the nervous system of gastrointestinal nematodes, causing them to paralyze and die, and then be excreted with feces. The use of this product can effectively eliminate gastrointestinal nematodes in dogs and improve their health condition.

Characteristics of the formulation
Good palatability
Afoxolaner tablets are usually designed as chewable tablets with good palatability, which are easy for dogs to accept and improve medication adherence. This is very convenient for pet owners, as there is no need to forcefully administer medication to their dogs.
Accurate dosage
Different specificatios of Afurana tablets can meet the medication needs of dogs of different weights, with accurate dosage, avoiding poor efficacy or adverse reactions caused by inaccurate dosage.
High stability
Through reasonable formulation process and packaging design, Aflana tablets have high stability and can maintain the activity and quality of the drug within the validity period. For example, sealed packaging can effectively isolate moisture and oxygen, extending the storage period of drugs.
Hot Tags: afoxolaner tablets, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale










