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Calcium beta hydroxy beta methylbutyrate (HMB) , also known as β - hydroxybutyrate calcium (HMB Ca), is an important organic compound. CAS 135236-72-5, molecular formula C10H18CaO6, white crystalline powder, sometimes slightly yellow in color. This compound is easily soluble in water, which makes it widely applicable in industries such as food, beverage, and medicine.
Widely used as food additives, such as acidity regulators, antioxidants, and acid enhancers. In the processing of canned fruits and vegetables, jams, jellies, candied fruits, and other foods, it helps to enhance the stability, freshness, and preservation of food. This compound is also used as a fabric softener and anti stripping agent in the textile industry; Used as additives and stabilizers in the paper industry to adjust the pH value of paper; Used as preservatives and stabilizers for electronic products in the electronics industry.
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Chemical Formula |
C10H18CaO6 |
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Exact Mass |
274.07 |
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Molecular Weight |
274.33 |
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m/z |
274.07 (100.0%), 275.08 (10.8%), 278.07 (2.2%), 276.08 (1.2%) |
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Elemental Analysis |
C, 43.78; H, 6.61; Ca, 14.61; O, 34.99 |
In summary, Calcium beta hydroxy beta methylbutyrate (HMB‑Ca) is a versatile organic compound with excellent water solubility and stable physicochemical properties. It not only serves as a reliable food additive to improve food stability and shelf life, but also extends its value to the textile, paper, and electronics industries as a softener, stabilizer, pH adjuster, and preservative. With its wide adaptability and safe application characteristics, HMB‑Ca has become an indispensable functional material across multiple industrial sectors.
The specific application examples of Calcium Beta Hydroxy Beta Methylbutyrate (HMB) in agriculture mainly revolve around its use as a plant growth regulator, feed additive, and soil amendment. The following is a detailed discussion on specific examples of its use in agriculture:
As a plant growth regulator
HMB Ca, as a plant growth regulator, has significant application effects in agriculture. It can promote plant growth and development, improve crop yield and quality by regulating metabolic processes within the plant body.
Promote crop growth
Calcium Beta Hydroxy Beta Methylbutyrate (HMB) Ca can promote the development of crop roots, enhance their absorption capacity, and thus improve the utilization efficiency of soil nutrients by crops.It can also promote photosynthesis in crops, increase chlorophyll content in leave.
Improve crop stress resistance
HMB Ca can enhance crop stress resistance, including drought resistance, cold resistance, and disease resistance. Under unfavorable conditions such as drought, cold, or disease, HMB Ca can protect the cell membrane and structure of crops, reduce cell damage, and thus improve crop survival rate and yield.
Improve crop quality
HMB Ca can improve the quality of crops, including increasing the sugar content, vitamin content, and taste of fruits. By regulating metabolic processes within plants, HMB Ca can promote fruit development and ripening, making the fruit fuller and sweeter.
As a feed additive
HMB Ca is also of great significance as a feed additive in animal husbandry. It can improve the growth performance, immunity, and health status of animals, thereby increasing the efficiency of aquaculture.
Promote animal growth
HMB Ca can promote animal growth, increase growth rate and feed conversion rate. By regulating the metabolic processes in animals, HMB Ca can increase their utilization of feed, reduce waste, and thus improve their growth performance.For example, the use of HMB Ca in animal husbandry can increase the weight.
Enhance animal immunity
HMB Ca can enhance animals' immunity, improve their disease resistance and health status. By regulating the immune system in animals, HMB Ca can increase their resistance to diseases and reduce the occurrence and spread of diseases.
Improve the quality of animal products
HMB Ca can also improve the quality of animal products, including enhancing the tenderness, flavor, and nutritional value of meat. By regulating the metabolic processes in animals, HMB Ca can improve the taste and nutritional value of meat.
As a soil amendment
Calcium Beta Hydroxy Beta Methylbutyrate (HMB) also has potential in soil improvement. It can improve soil structure, enhance soil fertility, and promote soil microbial activity, thereby improving the growth environment of crops.
Improve soil structure
HMB Ca can bind with minerals in soil to form stable soil aggregates, thereby improving soil structure and aeration. This helps to increase the soil's water retention capacity and permeability, providing a better growth environment for crop roots.
Improve soil fertility
HMB Ca can release nutrients from the soil and improve soil fertility. It can combine with nutrient elements in the soil to form a form that is easily absorbed and utilized by crops, thereby improving the nutrient content and utilization rate of the soil.
Promote soil microbial activity
HMB Ca can promote the activity of soil microorganisms and increase the number of beneficial microorganisms in the soil. This helps to improve the ecological environment of the soil, enhance its disease resistance and self-regulation ability.For example, applying HMB Ca to soil used for growing vegetables.
Application in fruit tree planting
HMB Ca can be used as foliar fertilizer or soil fertilizer in fruit tree cultivation. Applying HMB Ca to fruit trees through foliar spraying or soil irrigation can promote their growth and development, improve fruit quality and yield.
Foliar spraying:
HMB Ca is prepared into a certain concentration of aqueous solution and applied to fruit trees through foliar spraying. This can directly provide nutrients for fruit trees, promote photosynthesis of leaves and fruit development.
Soil fertilization:
Mix HMB Ca with organic or chemical fertilizers and apply it to the bottom of fruit trees through soil fertilization. This can improve the structure and fertility of the soil, providing a better growth environment for the roots of fruit trees.
Application in animal husbandry
HMB Ca can be used as a feed additive in animal husbandry. Adding HMB Ca to animal feed can improve their growth performance, immunity, and health status.
Broiler farming:
Adding HMB Ca to the feed of broiler chickens can increase their weight and growth rate, and shorten the slaughter time. Meanwhile, HMB Ca can also enhance the immunity of broiler chickens and reduce the occurrence and transmission of diseases.
Pig farming:
The use of HMB Ca in pig farming can reduce the mortality rate of pigs, improve the health status and production performance of pig herds. HMB Ca can also improve the quality of pork, making it more tender and delicious
Application in soil improvement
HMB Ca can be used as a soil amendment in soil improvement. Applying HMB Ca to soil can improve soil structure and fertility, enhance crop growth performance and yield.
Poor soil improvement:
Applying HMB Ca to poor soil can increase the organic matter and nutrient content of the soil, improve soil fertility and crop growth performance.
Saline alkali land improvement:
Applying HMB Ca in saline alkali land can neutralize the saline alkali components in the soil, reduce soil salinity, and provide a better environment for crop growth.
Health Benefits
Muscle Growth and Maintenance
One of the most well-established benefits of CaHMB is its ability to support muscle growth and prevent muscle loss. This is particularly relevant for athletes and bodybuilders who engage in intense training programs that can lead to muscle damage and breakdown. By reducing protein breakdown and stimulating protein synthesis, CaHMB helps promote muscle hypertrophy and strength gains.
In addition to its benefits for athletes, CaHMB may also be beneficial for older adults who are at risk of age-related muscle loss, known as sarcopenia. Sarcopenia is a significant public health concern, as it can lead to decreased mobility, increased risk of falls, and reduced quality of life. CaHMB supplementation has been shown to improve muscle mass and strength in older adults, potentially helping to prevent or delay the onset of sarcopenia.
Exercise Performance and Recovery
CaHMB has also been studied for its potential to improve exercise performance and enhance recovery after intense workouts. Several studies have reported that CaHMB supplementation can lead to improvements in strength, power, and endurance, as well as reductions in muscle damage and soreness.
For example, a study published in the Journal of the International Society of Sports Nutrition found that CaHMB supplementation improved muscle strength and power in resistance-trained men. Another study published in the European Journal of Applied Physiology reported that CaHMB reduced muscle damage and soreness following eccentric exercise.
Clinical Applications
In addition to its benefits for athletes and older adults, CaHMB has also been studied in various clinical populations. For example, individuals with HIV/AIDS often experience muscle wasting and weight loss, which can be exacerbated by the side effects of antiretroviral therapy. CaHMB supplementation has been shown to improve muscle mass and strength in these individuals, potentially helping to improve their quality of life.
CaHMB has also been studied in individuals with cancer, chronic obstructive pulmonary disease (COPD), and other chronic conditions where muscle wasting is a common issue.
Other Potential Benefits
Beyond its effects on muscle health, CaHMB may also have other potential health benefits. For example, some studies have suggested that CaHMB may help reduce cholesterol levels and improve cardiovascular health. Additionally, CaHMB has been shown to enhance immune function, which may be beneficial for individuals with compromised immune systems.
FAQ
- What is HMB beta-hydroxy beta-methylbutyrate?
A nutritional supplement containing the active metabolite of the essential amino acid leucine, with potential anti-catabolic and anabolic activities.
- Is it safe to take HMB every day?
Similarly, Matthew et al. [29] investigated whether 3 grams of HMB daily would benefit 70-y old adults. Results from this study also indicated no adverse effects from HMB supplementation. Thus, HMB appears to be safe when taken over several months, with 3–6 gram dosages in humans.
- Is calcium HMB good for you?
Daily HMB supplementation (typically 3 g/day) is demonstrated to have an anti-catabolic effect, enhance protein synthesis, attenuate proteolysis, increase muscle mass, and decrease muscle damage in older adults [20,24,25].
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