Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of pure alpha gpc powder in China. Welcome to wholesale bulk high quality pure alpha gpc powder for sale here from our factory. Good service and reasonable price are available.
Pure Alpha GPC Powder is a high-purity choline supplement, and its core component, alpha GPC (L - α - glycerophosphatidylcholine), is a naturally occurring phospholipid metabolic intermediate in the human body and a key precursor for the neurotransmitter acetylcholine and cell membrane phospholipids. Often exists in the form of white powder, slightly sweet, easily soluble in water and organic solvents. It is one of the few sources of choline that can efficiently penetrate the blood-brain barrier. Compared to traditional choline supplements such as choline bitartrate, its bioavailability is significantly higher, which can quickly increase choline levels in the brain and provide raw materials for acetylcholine synthesis. The efficacy of the compound remains unchanged when stored at room temperature for 2 years under sealed, dry, and dark conditions, but strong acids, bases, or high temperature environments should be avoided. Clinical studies have shown that daily intake of 300-1200mg has not reported serious side effects and is well tolerated. It also serves as a precursor of cell membrane phospholipids, and α - GPC can enhance the fluidity and toughness of neuronal cell membranes, activate neurotransmitter signaling pathways, and improve signal transmission efficiency.
At the same time, our company not only provides pure powders, but also tablets and injections. If needed, please feel free to contact us at any time.
Additional information of chemical compound:
| Product Name | Alpha GPC Powder | Alpha GPC Tablet | Alpha GPC Capsule | Alpha GPC Injection | Alpha GPC Spray |
| Product Type | Powder | Tablet | Capsules | liquid | Paste |
| Product Purity | ≥99% | ≥99% | ≥99% | ≥99% | ≥99% |
| Product Specifications | 100g/1kg/etc. | 300mg/600mg | 300mg/600mg | 0.5ml/1ml/2.25ml/3ml | 100ml/1l |
| Product Form | Organic synthesis | Take Orally | Take Orally | Organic synthesis | External application |
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Alpha GPC COA
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| Certificate of Analysis | ||
| Compound name | Choline glycerophosphate | |
| Grade | Pharmaceutical grade | |
| CAS No. | 28319-77-9 | |
| Quantity | 337.3kg | |
| Packaging standard | 25kg/drum | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202501090029 | |
| MFG | Jan 9th 2025 | |
| EXP | Jan 8th 2028 | |
| Structure |
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| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.37% |
| Loss on drying | ≤1.0% | 0.28% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.80% |
| Single impurity | <0.8% | 0.42% |
| Total microbial count | ≤750cfu/g | 90 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 500ppm |
| Storage | Store in a sealed, dark, and dry place below -20℃ | |
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Pure Alpha GPC Powder is a high-purity choline supplement, and its core component, alpha GPC (L - α - glycerophosphatidylcholine), is a naturally occurring phospholipid metabolism intermediate in the human body and a key precursor for the neurotransmitters acetylcholine and cell membrane phosphatidylcholine. It has a wide range of applications, covering multiple fields such as cognitive health, exercise performance, neuroprotection, and anti-aging. The following are its detailed uses:
Core components and mechanism of action
The molecular formula of Pure L - α - glycerophosphatidylcholine Powder is C ₈ H ₂ NO ₆ P, with a molecular weight of 257.22. One of the few sources of choline that can efficiently penetrate the blood-brain barrier. Compared to traditional choline supplements such as choline bitartrate, its bioavailability is significantly higher, which can quickly increase choline levels in the brain and provide raw materials for acetylcholine synthesis. Its mechanism of action can be summarized into the following three points:
Neurotransmitter synthesis
L - α - glycerophosphatidylcholine directly participates in the biosynthesis of acetylcholine by providing choline. Acetylcholine is one of the most important neurotransmitters in the central nervous system, responsible for regulating learning, memory, attention, and muscle contraction. Clinical studies have shown that L - α - glycerophosphatidylcholine can significantly increase acetylcholine levels in the brain and improve cognitive function.
Cell membrane repair and enhancement
L - α - glycerophosphatidylcholine, as a precursor of phosphatidylcholine, can be embedded into neuronal cell membranes to enhance membrane fluidity, toughness, and signal transduction efficiency. Animal experiments have shown that it can promote hippocampal neurogenesis and repair cognitive impairment caused by stress or epilepsy.
Antioxidant and anti-inflammatory effects
L - α - glycerophosphatidylcholine exerts anti-inflammatory effects by activating the α 7 nicotinic acetylcholine receptor, inhibiting the NF - κ B signaling pathway, and reducing the release of inflammatory factors such as TNF - α and IL-1 β. In addition, it can protect the function of mitochondrial complex I and alleviate oxidative stress caused by ischemia-reperfusion.
Core uses and clinical evidence
Alpha GPC has a wide range of applications, covering multiple fields such as cognitive health, athletic performance, neuroprotection, and anti-aging. Its effectiveness has been validated through multiple double-blind randomized controlled trials.
Alpha GPC is one of the commonly used drugs for treating Alzheimer's disease in Europe. In a 180 day double-blind trial, patients taking 1200mg L - α - glycerophosphatidylcholine daily (divided into 3 doses, 400mg each time) showed significant improvement in their Alzheimer's Disease Assessment Scale (ADAS Cog) and Mini Mental State Examination (MMSE) scores, while there was no change in the placebo group. Another 2-year study showed that the combination of L - α - glycerophosphatidylcholine and Aricept (donepezil) was more effective in delaying cognitive decline than Aricept alone. It can improve the attention, memory, and learning abilities of healthy adults. A cohort study involving participants without dementia found a positive correlation between choline intake and language memory, visual memory, and executive function.
In addition, L - α - glycerophosphatidylcholine can antagonize scopolamine induced temporary cognitive paralysis (amnesia). In continuous subtraction tests, the 400mg L - α - glycerophosphatidylcholine group performed 18% faster than the 200mg caffeine group, and had lower neurohypersensitivity scores. It can enhance central auditory processing ability. A study on patients aged 65-85 showed that taking 800mg L - α - glycerophosphatidylcholine daily for 11 months resulted in a 4.2% increase in bilateral word recognition scores, indicating that it may enhance auditory performance by improving brain processing ability.
Improved athletic performance
Pure L - α - glycerophosphatidylcholine Powder enhances muscle contractility by increasing acetylcholine levels and optimizing neuromuscular junction signal transmission. A study involving 7 resistance training men found that taking 600mg L - α - glycerophosphatidylcholine 90 minutes before exercise can increase peak growth hormone levels by 44 times (compared to only 2.6 times in the placebo group) and increase peak bench strength by 14%.
Another study showed that 630mg L - α - glycerophosphatidylcholine (high dose) significantly improved peak upper limb strength, while 315mg (low dose) showed even better improvement in lower limb strength, indicating muscle group specificity in dose-response. It promotes the secretion of growth hormone, assists in muscle growth, and shortens recovery time. Athletes often use it in combination with creatine, beta alanine, and other substances to enhance training effectiveness.
Alpha GPC can improve cognitive function in patients with acute or minor stroke. An Italian study showed that after receiving 1000mg L - α - glycerophosphatidylcholine injection for 28 days, patients switched to daily oral administration of 1200mg (divided into 3 doses) for 5 months, and 71% of patients did not experience cognitive decline, with a significant improvement in MMSE scores. Animal experiments have shown that can improve cognitive function after epileptic seizures, increase hippocampal neurogenesis, and reduce neuronal damage.
Anti aging and health maintenance
Alpha GPC supports liver cell membrane repair and toxin metabolism by providing phospholipids and choline, improving liver function indicators such as ALT and AST. Oral administration of Alpha GPC can stabilize tears, improve tear film quality in patients with dry eye syndrome, and maintain corneal transparency, which may be related to its protective effect on endothelial cells. Alpha GPC may improve mood and alleviate anxiety by increasing dopamine and serotonin levels. A study on healthy volunteers shows that their supplements can increase nighttime motivation without serious side effects.
Pure Alpha GPC, as a highly effective and safe choline supplement, demonstrates broad application prospects in the field of neurological health. From molecular mechanisms to clinical applications, it provides scientific support for addressing cognitive impairment, post-stroke recovery, and enhancing athletic performance by boosting acetylcholine synthesis, promoting neural repair, and inhibiting oxidative stress. Looking ahead, with advancements in personalized nutrition and novel delivery technologies, Alpha GPC is poised to become a vital tool in neurohealth management and precision nutrition, contributing significantly to human health and well-being.
Product advantages and technological innovation
Pure Alpha GPC Powder has significant advantages in purity, formulation design, and user experience, meeting the personalized needs of different populations.
High purity and stability
The product has a purity of 99%, avoiding interference from impurities and ensuring stable efficacy. New preparation technologies, such as microfluidics, achieve uniform particle size (D50<500nm), reduce agglomeration and blockage issues, and improve production efficiency.
Flexible dose adjustment
Powder formulations are convenient for adjusting dosage based on weight, age, and target. For example:
Cognitive improvement: 300-600mg/day, taken in 2-3 doses;
Exercise performance: 600-800mg/time, taken 15-20 minutes before exercise;
Dementia treatment: 1200mg/day, taken in 3 doses.
Excellent liquidity and user experience
By optimizing surface wettability and particle shape, the flowability of the product is significantly improved, making it easier to prepare and consume. For example, NNB Nutrition's GeniusPure ™ Alpha GPC uses a 90% high content formula, which has better flowability than traditional 50% content products and a 50% increase in stability.
Safety and usage recommendations
Safety assessment: Alpha GPC is classified as a GRAS (Generally Recognized as Safe) substance by the US FDA and approved as a natural health product by Canada. In clinical studies, daily intake of 300-1200mg has not reported serious side effects. Common adverse reactions include mild headache and nausea (incidence<5%), which usually disappear after continuous use.
Taboos and Precautions: Pregnant women, lactating women, and children should use with caution; Avoid co administration with anticholinergic drugs (such as scopolamine); Patients with liver and kidney dysfunction need to consult a doctor to adjust the dosage.
Suggestions for joint use: Cognitive enhancement: can be used in combination with phosphatidylserine (PS) and purslane extract; Sports performance: Used in combination with creatine, caffeine, or beta alanine;
Neuroprotection: Used in combination with Omega-3 fatty acids and vitamin B12.
Frequently Asked Questions
Does alpha gpc work immediately?
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Alpha-GPC increases acetylcholine levels almost immediately, so you can expect to feel the effects 20-30 minutes after ingestion. The effects of alpha-GPC last about four to six hours.
Is alpha gpc addictive?
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For active individuals prioritizing health, Alpha-GPC stands out as a low-risk alternative. It's well-tolerated with minimal side effects in studies, supporting sustained use without addiction or rebound crashes.
What does alpha gpc do for you?
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Alpha-glycerylphosphorylcholine (Alpha-GPC) and caffeine supplementation have been shown to improve mental and physical performance. Alpha-GPC administration increases the release of the neurotransmitter acetylcholine and facilitates learning and memory.
Is Alpha-GPC like nicotine?
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Alpha GPC also activates the acetylcholine receptors in your brain. That's going to give you the same focus energy locked in feeling the same learning, the same cognitive improvements that nicotine. However, it's not addictive and it's not going to give you a crash like nicotine will.
Does Alpha-GPC affect the liver?
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Taking α-GPC and supplementing with choline may improve liver dysfunction. Norepinephrine is secreted during stress and causes peripheral blood vessels to contract.
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