Sea Cucumber Peptide
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Sea Cucumber Peptide

Sea Cucumber Peptide

1.General Specification(in stock)
(1)API(Pure powder)
(2)Capsule
(3)Tablet
(4)Cream
2.Customization:
We will negotiate individually, OEM/ODM, No brand, for secience researching only.
Internal Code: BM-2-167
Sea Cucumber Peptide CAS 84625-50-3
Molecular formula: N/A
EINECS number: N/A
Hs code: N/A
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Analysis: HPLC, LC-MS, HNMR
Technology support: R&D Dept.-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of sea cucumber peptide in China. Welcome to wholesale bulk high quality sea cucumber peptide for sale here from our factory. Good service and reasonable price are available.

 

Among diversified bioactive constituents derived from marine invertebrate resources, sea cucumber peptide (CAS:84625-50-3), a heterogeneous oligopeptide mixture yielded via controlled enzymatic proteolysis of holothurian somatic protein with dispersed molecular weight ranging roughly from 500 Da to 3000 Da and favorable aqueous solubility alongside excellent transepidermal penetrability, has manifested distinctive application merits within dermal nursing and somatic metabolic modulation sectors by virtue of its inherent small-molecule transmembranous permeability and target-specific bioaffinity.

Its core physiological potency converges precisely on three pivotal functional orientations: impaired cutaneous barrier rehabilitation, endogenous oxidative lesion interception including radical scavenging and lipid peroxidation suppression, as well as accumulated physical fatigue mitigation. Relying on multi-channel biochemical modulation targeting epidermal tissue, intracellular genetic material and hepatic energy metabolism respectively, this peptide complex facilitates holistic somatic conditioning covering exterior cutaneous renovation and interior physiological homeostasis optimization. The subsequent content elaborates systematically on its underlying biochemical action pathways, distinctive pharmacodynamic attributes and corroborative experimental validation data from multi-dimensional research perspectives.

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Method of Analysis

Sea Cucumber Peptide COA

 Shaanxi BLOOM Tech Co., Ltd
Certificate of Analysis
Compound name Sea Cucumber Peptide
Grade Pharmaceutical grade
CAS No. 84625-50-3
Quantity Customized
Packaging standard Customized
Manufacturer Shaanxi BLOOM TECH Co., Ltd
Lot No. 202501090013
MFG Jan 9th 2026
EXP Jan 8th 2029
Structure N/A
Item Enterprise standard Analysis result
Appearance White or almost white powder Conformed
Water content ≤5.0% 0.54%
Loss on drying ≤1.0% 0.42%
Heavy Metals Pb≤0.5ppm N.D.
As≤0.5ppm N.D.
Hg≤0.5ppm N.D.
Cd≤0.5ppm N.D.
Purity (HPLC) ≥99.0% 99.98%
Single impurity <0.8% 0.52%
Total microbial count ≤750cfu/g 95
E. Coli ≤2MPN/g N.D.
Salmonella N.D. N.D.
Ethanol (by GC) ≤5000ppm 500ppm
Storage Store in a sealed, dark, and dry place, 2-8°C

 Shaanxi BLOOM Tech Co., Ltd

Applications | Shaanxi BLOOM Tech Co., Ltd

 

Efficacy Review of Sea Cucumber Price: Fatigue Relief alongside the Systematic Regulation of Bodily Energy Metabolism

 

The soothing effect of sea cucumber peptide on physical fatigue lies in regulating the excretion of metabolic products and the storage of energy substances in the body, alleviating discomfort caused by the accumulation of fatigue factors, and improving endurance. It can be divided into three aspects:

Regulation of fatigue metabolites
It can accelerate the metabolism and decomposition of lactate in the body, promote the activity of lactate dehydrogenase, reduce the accumulation of lactate in muscle tissue, and alleviate fatigue symptoms such as muscle soreness and fatigue.At the same time, it promotes the excretion of urea nitrogen, reduces its concentration in the blood, alleviates the metabolic burden on the kidneys, reduces fatigue caused by protein breakdown metabolism, and accelerates the recovery of fatigue in the body.

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Energy reserve enhancement

It can effectively promote the synthesis and storage of hepatic glycogen, significantly elevate glycogen accumulation within liver tissue, deliver stable and sustained energy supply for physiological metabolism, and alleviate physical fatigue triggered by inadequate energy reserve and consumption overload. It is especially suitable for rapidly replenishing physical energy after high-intensity exercise and heavy physical exertion, effectively prolonging physical endurance, delaying the onset of fatigue, and markedly improving the body's post-exercise recovery efficiency.

Regulation of metabolic enzyme activity

It can effectively upregulate the catalytic activity of multiple key enzymes linked to skeletal muscle energy metabolism, including pyruvate kinase and malate dehydrogenase. Such enzymatic activation further facilitates efficient progression of glycolysis and the tricarboxylic acid cycle inside muscle cells. By systematically optimizing core intracellular energy metabolism pathways, the agent elevates overall energy utilization efficiency, alleviates physical fatigue from the source, and consequently accelerates bodily recovery while enhancing athletic endurance.

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Sea Cucumber Supply Derivatives for Skin Barrier Repair and Damaged Sensitive Skin Soothing

 

 

The repairing effect of sea cucumber peptide on the skin barrier relies on its high permeability of small molecule structure, breaking through the barrier of the epidermal stratum corneum and directly reaching the deep layers of the skin, achieving the reconstruction of the barrier from the root and sensitivity relief. 

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01.Steady state reconstruction of stratum corneum
The specific amino acid components it contains can promote the proliferation and differentiation of keratinocytes, upregulate the expression levels of lactoglobulin (LOR) and filaggrin (FLG).Improve the loose state of damaged stratum corneum, fill the barrier gap, reduce the penetration of external stimuli, strengthen the skin's own water locking and protective ability, reverse the problems caused by barrier damage such as dryness and flaking, and achieve gradual recovery of barrier function.

02.Sensitive damage relief

Its active ingredients can efficiently inhibit the excessive release of various inflammatory mediators in the epidermis and dermis, and effectively antagonize the adverse skin stimulation induced by common allergic triggers including histamine. It visibly relieves a range of typical discomfort symptoms of sensitive and barrier-damaged skin, such as persistent flushing and redness, tight and dehydrated dryness, recurrent itching, as well as stinging and burning sensation caused by external irritation.

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Meanwhile, it can gradually lower the skin nerve sensitivity to external environmental stimuli like dry air, temperature changes and cosmetic irritation. It is especially suitable for problematic skin conditions such as seasonal periodic sensitivity, post-sun skin damage and weakened fragile skin barriers.

By calming epidermal inflammation and replenishing lipid barrier nutrients at the same time, it perfectly achieves a dual protective effect of mild instant soothing and long-term barrier repairing.

03.Regulation of Skin Microecological Balance

It can gently regulate the proliferation and colonization of beneficial microorganisms on the skin surface, while effectively inhibiting the reproduction and invasion of harmful bacteria. It maintains the dynamic balance and stability of the skin microecological flora, reduces skin barrier damage and allergic sensitivity triggered by microbial imbalance. Furthermore, it provides a healthy and stable microenvironmental foundation for gradual skin barrier repair, and effectively prolongs the lasting maintenance of skin repairing effects.

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Wound repair: accelerate tissue regeneration, inhibit scar hyperplasia

 

The core difficulties of wound healing lie in epidermal defects, collagen rupture in the dermis, local oxidative inflammatory stress, and slow growth of new tissues. Sea cucumber peptide can accelerate the wound repair process through multiple pathways and are suitable for repair scenarios such as traumatic wounds, minimally invasive postoperative wounds, and mucosal damage.

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Inhibit local oxidative inflammatory response

The wound repair period is prone to the accumulation of reactive oxygen species and the proliferation of inflammatory factors, which can cause redness, swelling, exudation, and delayed healing of the wound. This peptide component can clear local free radicals in the wound, reduce the release of inflammatory mediators, alleviate acute inflammatory reactions in the wound, improve the wound microenvironment, and avoid difficult wound healing caused by prolonged inflammation.

Regulate the migration and proliferation of epidermal cells

Small molecule peptides can penetrate damaged epidermal tissues, activate the proliferation and migration ability of keratinocytes and fibroblasts, quickly cover the wound defect area, while regulating the arrangement of new tissue, inhibiting the disorderly accumulation of collagen, reducing the probability of hypertrophic scars and pigmentation formation, and achieving efficient and low scar repair effects.

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Promote collagen synthesis and tissue remodeling

Sea cucumber protein peptides are rich in collagen specific amino acids such as proline and arginine, which can upregulate the gene expression of type I and III collagen in the body, fill collagen defects in the dermis of wounds, accelerate granulation tissue regeneration, provide basic material support for wound closure, and effectively shorten the wound healing cycle.

References

 

 

Olivera-Castillo M, et al. Antioxidant Activity of Sea Cucamber Protein Hydrolysates and Their Protective Effects on DNA Damage[J]. Journal of Marine Science and Engineering, 2024, 12(8): 1123-1135.
Anonymous Repair activity of sea cucamber oligopeptides on skin barrier damage [J]. VIP Journal, 2024, (05):7202560386.
Li J, Wang H, Zhang Y. Sea Cucamber Peptides Alleviate Physical Fatigue by Regulating Energy Metabolism and Oxidative Stress[J]. Journal of Functional Foods, 2024, 118: 105892. 

Enzymatic Hydrolysis-Assisted Separation and Purification of High F-Value Oligopeptides from Sea Cucumbers and Their Anti-Fatigue Mechanism(https://pmc.ncbi.nlm.nih.gov/articles/PMC12842808/)

FAQ

How long does the effectiveness of sea cucamber protein peptide in repairing the skin barrier manifest?

In general, continuous use of skincare products or supplements containing sea cacumber protein peptides for 2-4 weeks can result in significant improvement, gradually relieving symptoms of sensitivity, redness, dryness, and itching, and increasing the tightness of the stratum corneum. The specific cycle may vary slightly depending on individual skin conditions, and those with severe barrier damage may need to persist in use for a longer period of time.

What are the unique advantages of its ability to scavenge free radicals compared to common antioxidant components?

Compared to traditional antioxidant components, the small molecular structure of sea cucamber protein peptides is more easily permeable to the interior of cells. They can not only directly scavenge DPPH and hydroxyl radicals, but also inhibit lipid peroxidation chain reactions. At the same time, they provide more targeted protection for cells and DNA, and can still retain high activity after gastrointestinal digestion, making them more widely applicable in various scenarios.

What are the details to pay attention to when using skincare products containing sea cucamber protein peptides for sensitive skin?

It is recommended to conduct a local skin test before using sensitive skin for the first time, avoiding damaged or inflamed areas; Prioritize selecting sea cucamber protein peptide products with high purity and molecular weight ≤ 2000Da to reduce skin irritation; Paired with a gentle and non irritating skincare routine, avoiding the use of powerful cleansing and exfoliating products, it is more conducive to repairing the skin barrier and soothing sensitivity.

 

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