Cyclohexapentylose CAS 10016-20-3

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of cyclohexapentylose cas 10016-20-3 in China. Welcome to wholesale bulk high quality cyclohexapentylose cas 10016-20-3 for sale here from our factory. Good service and reasonable price are available.

Cyclohexapentylose is a cyclic oligosaccharide composed of six glucose units linked end-to-end through α-1,4-glycosidic bonds. It is named because of its structure containing six units and often being confused with the concept of a pentagonal ring. As an important member of the cyclodextrin family, although it is not as widely used as the common β-cyclodextrin (with a seven-membered ring), its unique conical cavity structure still endows it with excellent host-guest inclusion capabilities - the external hydrophilic and internal hydrophobic cavity can selectively encapsulate small molecule organic substances, forming stable inclusion complexes. This property makes it shine in the pharmaceutical industry as a drug solubilizer and stabilizer, effectively improving the bioavailability of active ingredients; in the field of food science, it acts as a protective carrier for flavor substances, preventing volatilization and oxidation; in environmental analysis, it is used for pollutant extraction and detection, demonstrating precise molecular recognition potential. Its precise structure and adjustable properties make it an ideal module for constructing intelligent materials and delivery systems in supramolecular chemistry, continuously driving the innovation and development of functional materials and green technologies.

Cyclohexapentylose has a hole in the center of the ring structure, and there is - CH - oxygen atom combined with glucoside inside, which is sulfur-hydrophilic. The - OH group at the 2, 3 and 6 positions of glucose is hydrophilic. It can synthesize other molecules into inclusion complexes through weak van der Waals force. There are many substances that can be encapsulated by cyclodextrins, including rare gases, halogens, dyes, spices, drugs, foods, pesticides and preservatives. After encapsulation, its stability, volatility, solubility and reactivity were improved. The special function of cyclodextrin makes it become an inclusion material with wide application value.

1. Use in the pharmaceutical industry. Cyclodextrins can be used to form inclusion complexes (encapsulation) with drugs, which have the following effects:

(1) Unstable drug stabilization;

(2) Deliquescence, adhesion or liquid drug powder;

(3) Insoluble or insoluble drugs can be dissolved (solubilized), etc.

2. Application in pesticide industry: cyclodextrin inclusion stabilization, and some pesticides can be resistant to storage and improve insecticidal efficacy.

3. Use in the food industry Cyclodextrin is used in the food industry and has the following functions:

(1) Elimination and cover up of peculiar odor;

(2) Improvement and improvement of food organization structure;

(3) Mitigation and removal of bitter taste;

(4) Antioxidant effect;

(5) Maintain and improve the flavor.

4. Use in daily chemical industry Cyclodextrin can also be used as emulsifier and quality improver in cosmetics manufacturing. It also has the function of deodorization (such as removing bad breath) and antisepsis, and can be used in the manufacture of toothpaste and tooth powder.

5. Other uses can be used as a treatment agent for oily sewage in environmental protection. The aqueous solution of cyclodextrin is used to clean the oil tank, and the waste liquid can be recycled and treated to obtain fuel oil.

6. Application of cyclodextrin in chemical field Cyclodextrin is a valuable chemical reagent. When it exists, the fluorescence intensity of fluorescent pigment will increase significantly, so it can be used for the analysis of protein and amino acid; It can also be used to separate long-chain organic compounds and racemates. In addition, the adsorbent made of cyclodextrin can be used for adsorption of chromatographic analysis.

α- Ring paste refining preparation:

1. Mix cassava starch and distilled water at a concentration of 15% to form a pulp, and stir at 85 ℃ for 15 minutes to make the starch particles fully swell and dissolve.

2. Adjust the PH value to 5, add CGT enzyme according to the proportion of 200 units per gram of starch, and then add n-decanol which accounts for 8% of the mass of starch, and react for 6 hours.

3. Separate n-decanol from the reaction solution by steam distillation.

4. Adjust the temperature to 50 ℃, and then add CGT enzyme to make the proportion reach 400 units per gram of starch; Add 20% ethanol by volume of starch, and then react for 10 hours.

5. Filter the reaction solution directly and collect the filter cake, including ethanol and α- Precipitation of complex formed by cyclodextrin and unreacted starch; Re-dissolve the filter cake, remove the ethanol by vacuum distillation, and after distillation, filter the distillate to remove the unreacted starch α- Aqueous solution of cyclodextrin; Evaporate and concentrate the aqueous solution and place it in a low temperature environment of 2 ℃ cyclohexapentylose of cyclodextrin.

Cyclodextrin is the general name of a series of cyclic oligosaccharides produced by amylose under the action of cyclodextrin glucosyltransferase produced by Bacillus, which usually contains 6-12 D-glucopyranose units. Among them, the molecules with 6, 7 and 8 glucose units, which have been studied more and have important practical significance, are called α-,β- and γ- Cyclodextrin (Fig. 1). According to the results of X-ray crystal diffraction, infrared spectrum and nuclear magnetic resonance spectrum analysis, it is determined that each D (+) - glucopyranose that constitutes the cyclodextrin molecule is a chair conformation. Each glucose unit is bound to form a ring with 1,4-glycosidic bonds. Because the glycosidic bond connecting the glucose unit cannot rotate freely, the cyclodextrin is not a cylindrical molecule but a slightly conical ring. Among them, the primary hydroxyl group of cyclodextrin forms a small conical mouth, while the secondary hydroxyl group forms a large conical mouth.

Because the rim of cyclodextrin is hydrophilic and the cavity is hydrophobic, it can provide a hydrophobic binding site like an enzyme, and as a host, envelop various appropriate guests, such as organic molecules, inorganic ions and gas molecules. This selective enveloping action is commonly known as molecular recognition, and the result is the formation of host-guest complex. Cyclodextrin is an ideal host molecule similar to enzyme found so far, and it has the characteristics of enzyme model itself. Therefore, cyclodextrins have received great attention and wide application in the fields of catalysis, separation, food and medicine.

α- In addition to the characteristics and uses of other CDs α- The inner dimension of CD is smaller than cyclohexapentylose, which is more suitable for the inclusion of small molecules, as well as applications requiring high solubility of CD.

1.Potential side effects

2.Security considerations in different fields of application

Pharmaceutical field

 

In the field of medicine, this substance is often used as a drug encapsulation agent to improve the stability and bioavailability of drugs. However, when using it as a drug excipient, it is necessary to fully consider its impact on drug efficacy and safety. Especially for patients who require long-term medication, liver and kidney function indicators should be regularly monitored to ensure medication safety.

Food sector

 

In the food industry, it is often used as a food additive to improve the taste, texture, and stability of food. However, the content of this substance in food should be controlled within a safe range to avoid adverse effects on consumers. At the same time, special attention should be paid to the tolerance and safety of specific populations (such as pregnant women, infants, etc.) to alpha cyclodextrin.

Cosmetics field

 

In the field of cosmetics, it is often used as an emulsifier, stabilizer, and thickener. However, the content of alpha cyclodextrin in cosmetics should also be controlled within a safe range to avoid irritation or allergic reactions to the skin. Before using cosmetics containing this substance, it is recommended to undergo skin testing to ensure its safety.

3.Strategies to reduce the side effects of this substance

1. Sales price differences among different manufacturers
Due to differences in production costs, production processes, brand influence, and other factors, the selling prices of materials may also vary among different manufacturers. Some well-known brands or large manufacturers may have relatively high sales prices due to their economies of scale and high product quality; Some small manufacturers or emerging brands may adopt a low price strategy in order to seize market share.

2. The impact of product quality on sales price
Its product quality directly affects its selling price. High quality products usually have better stability and application effects, so their sales prices will be correspondingly higher. On the contrary, low-quality products may have lower prices, but their effectiveness may be poor, and they may even have a negative impact on the application product.

3. Purchase quantity and price discounts
The purchase quantity is also an important factor affecting the price of the substance. Generally speaking, the larger the purchase quantity, the greater the price discount offered by the manufacturer. This is because large-scale procurement can reduce the sales and logistics costs of manufacturers, thereby improving their profitability.

4. The impact of sales channels on prices
Different sales channels can also lead to differences in sales prices. For example, products purchased through direct sales channels may have relatively lower prices because direct sales reduce intermediate links and distribution costs; Products purchased through agents or distributors may have higher prices as these channels require additional distribution fees and commissions.

5. Market demand and price fluctuations
Changes in market demand can also affect its sales price. When market demand is strong, manufacturers may raise sales prices to obtain higher profits; When market demand is sluggish, manufacturers may lower sales prices or offer more promotional activities to boost sales.

The discovery of this compound can be traced back to the early 20th century, when chemists began to have a strong interest in complex carbohydrate structures. In 1903, German chemist Emil Fischer first proposed the concept of cyclic sugar structures while studying carbohydrate compounds. This discovery laid the foundation for further research on cyclohexanol. However, it was not until the 1930s that the specific structure of cyclohexanol was gradually revealed. In 1934, British chemist Walter Norman Haworth successfully synthesized cyclohexanol for the first time while studying the stereochemistry of carbohydrate compounds. Haworth obtained the crystal structure of cyclohexanol by cyclization reaction of glucose molecules, and determined its molecular configuration using X-ray diffraction technology. This breakthrough discovery not only confirms the existence of cyclic sugar structures, but also provides important experimental evidence for subsequent sugar chemistry research. In the 1940s and 1950s, with the advancement of analytical techniques such as nuclear magnetic resonance (NMR) and infrared spectroscopy (IR), scientists gained a deeper understanding of the structure and properties of cyclohexanol. In 1947, American chemist Melvin Calvin further analyzed the stereochemistry of cyclohexanol using NMR technology, revealing its hydrogen bonding network and spatial arrangement within the molecule. These studies have laid a solid theoretical foundation for the synthesis and application of cyclohexanol.

Hot Tags: cyclohexapentylose cas 10016-20-3, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, 3 Nitrobenzaldehyde 99 , Additive, gs 441524 remdesivir, Methylamine hydrochloride powder, 2 Chloro 4 pyridinecarboxylic acid, 3 Phenyltoluene