Soybean Oligopeptide

Molecular structure: The average molecular weight is ≤ 1000 Da, with over 80% being 2-6 amino acid short peptides, and dipeptides and tripeptides accounting for ≥ 70%. Small molecules are easy to penetrate tissue barriers and are suitable for drug carriers and targeted delivery needs.
High purity and stability: pharmaceutical grade purity ≥ 90%, health grade ≥ 85%; Resistant to high temperatures (not decomposed at 120 ℃), acid and alkali (stable at pH 3-10), and processing, it can be used in the production of various dosage forms such as tablets, capsules, oral liquids, freeze-dried powder injections, etc.

Low antigenicity: The antigenicity is only 1/100 of ordinary soy protein, with almost no allergy risk. It is suitable for allergic constitution, infants, and postoperative immunocompromised population, and meets pharmaceutical grade safety standards.
Excellent water solubility: 100% soluble in water, the aqueous solution is clear and transparent, without precipitation or bean odor, suitable for liquid dosage forms such as injections, oral liquids, and nutrient solutions, solving the pain points of low solubility and easy precipitation of ordinary proteins.

Direct absorption without digestion: without the need for pepsin or trypsin decomposition, it is directly absorbed through the PepT1 transporter in the small intestine, entering the bloodstream in 5 minutes and reaching the peak plasma level in 15 minutes. The bioavailability is ≥ 95%, far exceeding that of ordinary soy protein (60% -70%) and free amino acids (80% -85%).

Bypass the gastrointestinal barrier and adapt to special populations: It does not rely on gastrointestinal digestive function and is suitable for postoperative gastrointestinal failure, mucosal damage caused by radiotherapy and chemotherapy, chronic enteritis, and elderly people with insufficient secretion of digestive enzymes who cannot digest large molecular proteins. It is the core material of clinical nutritional support.
Strong tissue penetration and targeted delivery potential: Small molecule structures can penetrate the blood-brain barrier, tumor tissue barrier, and skin barrier, and can be used as drug carriers, radionuclide carriers, and targeted formulation excipients to enhance drug bioavailability and targeting.

Target audience: Patients who have undergone abdominal surgery, orthopedic surgery, organ transplantation, minimally invasive surgery, have not recovered gastrointestinal function, are unable to eat a regular diet, and have a high demand for tissue damage repair.
Mechanism of action: Directly absorb and rapidly supplement high-quality protein, promote collagen and muscle protein synthesis, accelerate surgical incision healing, repair damaged tissue, correct negative nitrogen balance, enhance immunity, and reduce infection risk.

Clinical evidence: A randomized controlled trial of 80 postoperative abdominal patients showed that supplementing 15g of soy oligopeptides daily for 2 weeks resulted in an 18% increase in serum albumin, a 25% increase in prealbumin, a 30% reduction in incision healing time, and a 40% reduction in infection rate, significantly better than the regular protein powder group.
Dosage case: Postoperative nutrition powder, oral nutrition solution, enteral nutrition emulsion, such as "soy oligopeptide enteral nutrition suspension", containing 10% soy oligopeptide, complex vitamins, minerals, can be directly taken orally or nasogastric feeding, suitable for patients with weak gastrointestinal function.

Target audience: Cancer patients undergoing radiotherapy and chemotherapy, who suffer from gastrointestinal mucosal damage, nausea and vomiting, decreased appetite, bone marrow suppression, weakened immunity, and malnutrition caused by radiotherapy and chemotherapy.
Core value: Dual protection - nutritional support+alleviation of toxic side effects. On the one hand, it does not require digestion, rapid absorption, supplements nutrition, and improves cachexia; On the other hand, it can repair gastrointestinal mucosa, alleviate nausea and vomiting, reduce bone marrow suppression, increase white blood cells and platelets, enhance immunity, and reduce the risk of infection.

Mechanism of action: Contains arginine and glutamine precursors to repair the intestinal mucosal barrier damaged by radiotherapy and chemotherapy; Antioxidant activity clears free radicals generated by radiotherapy and chemotherapy, reduces normal cell damage; Immune regulatory activity activates bone marrow hematopoietic stem cells and alleviates bone marrow suppression.
Dosage case: Chemotherapy specific nutritional powder, compound peptide oral solution, bone marrow protective nutrient, often combined with ginseng polysaccharide, Ganoderma lucidum polysaccharide, vitamin B group, to enhance immunity, relieve fatigue, and improve appetite.

Lowering blood pressure: Contains ACE inhibitory peptide, which inhibits angiotensin-converting enzyme, dilates peripheral blood vessels, lowers blood pressure, reduces systolic blood pressure by 5-10mmHg, gently lowers blood pressure, has no side effects, and is suitable for mild hypertension.
Regulate blood fat: inhibit cholesterol synthesis, promote cholesterol excretion, reduce TC/TG/LDL-C, increase HDL-C, reduce lipid deposition in vascular wall, repair vascular endothelium, and prevent atherosclerosis.

Clinical evidence: Daily supplementation of 5g soy oligopeptides for 8 weeks in patients with hyperlipidemia resulted in a 12% decrease in total cholesterol, an 18% decrease in triglycerides, a 10% decrease in LDL-C, and a 6% increase in HDL-C, significantly improving the lipid profile.
Dosage examples: Antihypertensive peptide tablets, lipid-lowering nutritional powder, cardiovascular protective oral solution, combined with fish oil, nattokinase, and coenzyme Q10, enhance vascular protection and prevent thrombosis.

Mechanism of action: Inhibit alpha glucosidase activity, delay carbohydrate breakdown, reduce glucose absorption, stabilize postprandial blood glucose, improve insulin resistance, protect pancreatic beta cells, and reduce insulin secretion.

Clinical evidence: Tyr Phe and His Pro sequences in soy oligopeptides have an IC50 value of 0.87 mg/mL for alpha glucosidase, which is superior to acarbose (1.32 mg/mL); Postprandial blood glucose peak decreases by 30% -40%, reducing blood glucose fluctuations and lowering glycated hemoglobin.
Dosage form cases: hypoglycemic peptide powder, nutrition powder for diabetes, insulin protection oral liquid, with white kidney bean extract, mulberry leaf extract, chromium, to stabilize blood sugar, improve insulin resistance, and prevent complications.

Mechanism of action: Repair liver cells, promote liver cell regeneration, reduce transaminase levels, accelerate alcohol metabolism, reduce acetaldehyde accumulation, resist oxidation and inflammation, prevent liver fibrosis, regulate fat metabolism, and improve fatty liver.