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October 22, 2024
Metandienone powder , also known as dihydrotestosterone, is an important pharmaceutical compound with the chemical name 17b-hydroxy-17a-methyl-1,4-androsterodiene-3-one. It is a white to grayish white crystalline powder with high purity and stability. The molecular formula is C20H28O2, CAS 72-63-9, and the molecular weight is 300.43500. Mesandrosterone has a wide range of applications in the medical field, mainly used to promote protein synthesis, inhibit protein heterogenesis, maintain positive nitrogen balance, and has significant therapeutic effects on chronic wasting diseases, osteoporosis and other diseases. It has the function of promoting protein synthesis, inhibiting protein heterogenesis, maintaining positive nitrogen balance, enhancing appetite, promoting muscle growth and weight gain. It has the effect of promoting calcium and phosphorus deposition in bone tissue, promoting interstitial formation of bone cells, accelerating bone calcification and growth.
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Chemical Formula |
C20H28O2 |
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Exact Mass |
300 |
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Molecular Weight |
300 |
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Elemental Analysis |
C, 79.96; H, 9.39; O, 10.65 |
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Clinical application of metandienone powder:
After androgen or anabolic hormone is applied to female patients, it may cause masculinity, such as hirsutism, long beard, rough voice, low pitch, acne, etc. The symptoms may gradually subside after drug withdrawal. Long term use of this kind of hormone in male patients may convert the drug into estrogen in the body, and may also inhibit the secretion of gonadotropin, causing testicular atrophy and inhibiting spermatogenesis; The inhibition of endogenous testosterone can lead to impotence.
Dehydromethyltestosterone
The long-term use of androgen in children can seriously affect the growth and development. For example, the effect of accelerating epiphyseal closure can last for several months after drug withdrawal; The use of anabolic hormones can lead to obesity. 17 Yes α- Methyl androgen has serious damage to the liver, mainly interfering with the excretion function of the intrahepatic bile capillaries, causing cholestasis in the central bile capillaries of the liver lobules, causing cholestasis liver cell damage. Its clinical manifestation is cholestasis hepatitis.
Long term use of androgen may lead to liver cancer, prostate cancer and renal cell carcinoma. In addition, it can cause edema due to its retention of water and sodium. Use with caution for patients with kidney disease and heart failure, and use with caution for pregnant women with prostate cancer.
Pharmacological effect of metandienone powder:
It is a dehydrogenated derivative of methyltestosterone, but the effect of androgen is small and the protein assimilation is strong. Its protein assimilation is the same as that of testosterone, the androgen activity is about 1/100 of the latter, and the differentiation index is 3. It can promote protein synthesis, inhibit protein heterogenesis, maintain positive nitrogen balance, and improve appetite, muscle growth and weight gain.
It can promote the deposition of calcium and phosphorus in bone tissue, promote the formation of bone cell interstitium, accelerate bone calcification and bone growth. Promote tissue regeneration and granulation formation, and accelerate the repair of wounds and ulcers. Lower blood cholesterol and improve lipid metabolism.
It is a dehydrogenated derivative of methyltestosterone, but the effect of androgen is small and the effect of protein assimilation is strong. Its protein assimilation is the same as testosterone propionate, its androgen activity is about 1/100 of the latter, and its differentiation index is 3.
Pharmacological effects:
1. Androgen activity
Although the androgen activity of testosterone is relatively weak, it can still effectively stimulate the development of male sexual characteristics and maintain male secondary sexual characteristics. For men, testosterone can enhance libido, enhance sexual ability, and stimulate the prostate and seminal vesicles.
2. Protein assimilation
Mesandrosterone has a significant protein assimilation effect, which can promote the synthesis of muscle proteins and inhibit their decomposition. This makes testosterone an effective drug for promoting muscle growth. In addition, testosterone can also enhance physical strength and improve endurance.
3. Anti estrogen effect
Mesandrosterone has significant anti estrogen effects and can competitively inhibit the binding of estrogen to target organs, thereby reducing the physiological effects of estrogen. This makes methandrone in some cases can be used to treat estrogen dependent tumors such as breast cancer and endometrial cancer.
4. Other pharmacological effects
Metandienone Powder also has anti osteoporosis, anti-inflammatory, and immunomodulatory effects. It can inhibit the activity of osteoclasts, reduce bone loss, and prevent osteoporosis. In addition, testosterone can also alleviate inflammation by inhibiting the release of inflammatory factors. In addition, testosterone can also regulate the immune system and enhance immunity.
Some people believe that after using Metadienone, there will be a significant amount of moisture. The phenomenon of increased fat leads to the belief that vigorously tonifying muscles is not effective, thus negating vigorously tonifying. In fact, this is a strong remedy for the injustice suffered.
Researchers from the Department of Physiology and Medicine at Leeds University in the UK and the School of Human Sciences at Birmingham University have conducted a safety test to investigate the impact of physiological and cognitive indicators on athletes. In the experiment, researchers selected 11 professionally trained lifters and randomly assigned a 100mg daily dose of vigorous supplement to some participants (100mg daily vigorous supplement is equivalent to 10 commercially available vigorous supplements). The other subjects were treated with analgesics for a period of 6 weeks. The training movements required by the researchers before and after the experiment were squats and push ups, which were conducted according to their respective training habits (as these 11 participants were all experienced weightlifters who had been trained for years). Before and after the experiment, researchers measured the body weight, blood potassium levels, nitrogen levels in the body, muscle volume, and strength performance of all participants.
The experimental results showed that, The subjects who received Metadienone treatment had an average body weight of 3.6kg higher than the control group, and their levels of ammonia were 217g higher than the control group. Their blood potassium levels were 488mmol higher than the control group. Their lean body weight was 3.17kg higher than the control group (with a significant level of 0.001), while their body fat decreased compared to the control group (with an average decrease of about 2mm measured by body fragility thickness). In terms of strength improvement, it goes without saying that the vigorous supplementation group outperformed the control group in seconds (The maximum increase in upper and lower limb strength exceeded 13kg), and it is worth mentioning that after 6 weeks of training, the thigh range and arm circumference actually decreased. Moreover, the pulling eye and leg strength also decreased significantly The above data illustrates several directions
Metandienone Powder does not actually store fat as many people imagine: Elevated blood potassium levels mean that the body needs to reserve renamed water to balance osmotic pressure. After analyzing the body composition, the experimenters concluded that the water content of muscle cells also increased correspondingly. This indicates that Metadienone is not simply increasing the amount of intercellular fluid, but rather making muscle cells fuller and fuller, and the increase in blood potassium can help improve the user's strength performance, which is in line with the improvement of relevant strength indicators. In addition, the daily 100mg 6-week vigorous supplement experiment did not show any adverse side effects, indicating the high safety of vigorous supplement. Add two more sentences: A training program aimed at improving muscle mass and muscle circumference. Without the support of a synthetic metabolic environment, it will actually become more and more difficult to train. This is very important. Many trainers believe that as long as they train hard, they can obtain the necessary muscles and strength. The opposite is true in the market: people cannot surpass the sky. Just having a warm and energetic mind and not following scientific and regular training can only backfire.
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