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Testosterone Isocaproate CAS 15262-86-9
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Testosterone Isocaproate CAS 15262-86-9

Testosterone Isocaproate CAS 15262-86-9

Product Code: BM-2-6-087
CAS number: 15262-86-9
Molecular formula: C25H38O3
Molecular weight: 386.57
EINECS number: 239-307-1
MDL No.: MFCD00133848
Hs code: /
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October 22, 2024

Testosterone isocaproate is a synthetic androgen derivative that is one of the esterified forms of testosterone. Molecular formula: C25H38O3, CAS 15262-86-9, relative molecular mass: 386.567 g/mol. The chemical structure consists of a testosterone molecule linked to an isovalerate group. The common appearance is white or off-white crystalline solid. It may come in different forms such as powder, crystals or crystalline flakes. It has good solubility in some organic solvents, such as ethanol, dimethyl sulfoxide and dichloromethane. It has low solubility in water. Is a fat-soluble substance, it is more soluble in non-polar organic solvents, such as oils or fatty acid esters. This makes it available as an oil solution in injections. It is a photosensitive substance that is easily degraded by ultraviolet rays. Therefore, it usually needs to be stored under dark conditions.

Produnct Introduction

Testosterone isocaproate | Shaanxi BLOOM Tech Co., Ltd

 

Testosterone isocaproate | Shaanxi BLOOM Tech Co., Ltd

 

Chemical Formula

C25H38O3

Exact Mass

386

Molecular Weight

387

m/z

386 (100.0%), 387 (27.0%), 388 (2.7%)

Elemental Analysis

C, 77.68; H, 9.91; O, 12.42

product-1-1

It is a synthetic androgen derivative with a variety of uses. The following are common applications for product:

1. Alternative therapy:

Testosterone isocaproate is widely used in male testosterone replacement therapy for the treatment of low testosterone due to hypotesticular function or orchidectomy. Also known as testosterone replacement therapy, this therapy can help restore normal testosterone levels, improve libido, sexual function, and sexual characteristics, and reduce symptoms such as fatigue and depression.

2. Promote muscle growth:

It is also used by some fitness enthusiasts and sports athletes to promote muscle growth and increase muscle strength. A testosterone ester compound, can be injected to give the body extra testosterone, thereby increasing protein synthesis, and improving the speed and quality of muscle growth.

3. Prevent osteoporosis:

Testosterone is a key regulator that plays an important role in maintaining bone health. Low testosterone levels may lead to an increased risk of osteoporosis. Therefore, It may also be used in some cases to treat and prevent osteoporosis in men.

Testosterone isocaproate use | Shaanxi BLOOM Tech Co., Ltd
Testosterone isocaproate use | Shaanxi BLOOM Tech Co., Ltd

4. Relieve menopausal symptoms:

For some women, menopause means a drop in testosterone levels. It can be used in some cases to relieve menopausal symptoms such as mood swings, decreased libido, and fatigue.

5. Prolong the function of gonads:

Sometimes, It is also used to treat certain male reproductive disorders such as testicular atrophy or testicular insufficiency. It can help restore normal function of the gonads and boost testosterone production.

6. Research and laboratory applications:

It as a commonly used testosterone ester compound, is also widely used in scientific research and laboratories. It is often used in in vivo and in vitro experiments to explore the mechanism of action of testosterone in physiology and pharmacology.

It should be noted that the use of It should be based on the guidance of a doctor or professional, and strictly follow the correct dosage and method of use. This ensures safety and maximizes the drug's effects. In addition, there may be differences in the legal use and supply of It in different countries, so it is necessary to understand the local regulations and policies before use.

Manufacturing Information

Briefly introduce the general steps of the synthetic method of product.

Testosterone isocaproate is a synthetic androgen derivative whose synthesis usually involves the following steps:

 
Starting material

The synthesis of It usually starts with raw chemicals such as androstenone or dehydroepiandrosterone (DHEA).

 
Oxidation reaction

The starting material is first subjected to an oxidation reaction, such as oxidation, rearrangement or ketonization, etc., to obtain the desired intermediate product. These reactions can be carried out by various methods using oxidizing agents or enzyme catalysts.

 
Compound protection

In order to prevent the interference or reaction of some functional groups, the compounds can be protected with protecting groups. This can be achieved through selective functional group protection reactions.

 
Functional group conversion

During the synthesis of product, a series of chemical transformation reactions will be carried out, including substitution, esterification, acylation, deprotection, etc., to introduce or change the required functional groups.

 
Esterification reaction

The final step is the esterification of isovaleric acid with the desired Testosterone derivative to form it.

 

Testosterone isocaproate use | Shaanxi BLOOM Tech Co., Ltd

It should be noted that the specific steps, conditions, catalysts and other factors of the synthesis method may vary depending on the research institution, synthesis target, etc. In addition, since It is a controlled drug, its synthesis and use are subject to strict regulations. Therefore, any practical application of the synthetic method of It should follow the applicable laws and regulations and be carried out in a qualified laboratory.

chemical property

Testosterone isocaproate is a synthetic androgen derivative with a variety of chemical properties, including:

 

1. Molecular structure:The molecular formula of It is C25H38O3, and the molecular weight is 386.57 g/mol. It is a fat-soluble compound that usually exists as a white to yellowish powder.

 

2. Acidity and alkalinity:It is a neutral compound, almost insoluble in water, but soluble in organic solvents such as ethanol, dimethyl sulfoxide, etc.

 

3. Thermal stability:It is relatively thermally stable under appropriate conditions. However, excessively high temperatures or prolonged heating may cause it to decompose.

 

4. Photostability:Because It contains certain unsaturated structures, it is highly sensitive to light and prone to photodegradation. Therefore, long-term exposure to light should be avoided during storage and use.

 

5. Solubility:It is relatively soluble in common organic solvents, such as ethanol, dimethyl sulfoxide, acetone, etc. However, the solubility in water is relatively low.

 

6. Chemical reaction:It can participate in various chemical reactions, such as ester hydrolysis, oxidation reaction, substitution reaction, etc. These chemical reactions can be initiated by appropriate reagents and catalysts.

 

7. Stability:It is relatively stable under appropriate conditions, but it may be affected by factors such as light, heat, oxidation and hydrolysis to lose its activity. Therefore, during storage and use, contact with the above factors should be avoided.

 

It should be noted that in research and application, applicable laws and regulations must be followed and relevant experiments carried out in a qualified laboratory environment.

Discovering History

Describe the history of the development of Testosterone isocaproate.

 

Early research:
In the 1950s and 1960s, scientists conducted extensive research on testosterone and its derivatives. Studies have shown that androgen can promote gonad development, maintain secondary sexual characteristics, regulate sexual function, and protein synthesis. However, due to the low bioavailability of testosterone, scientists began to try to synthesize more stable derivatives with better effects.

 

Development of synthetic methods:
As technology advances, so do synthetic methods. In the 1970s, scientists developed a synthetic method for product. This method involves reacting isovaleric acid with Testosterone to form an esterified product. The synthetic method of It has been widely used in drug development and medical applications.

 

Development of medical applications:
It has testosterone-like biological activity and therefore has a range of applications in medicine. It is widely used to treat androgen deficiency, low libido, muscle weakness, breast cancer and other conditions. In addition, It is also used as an endocrine replacement therapy for regulating the function of the endocrine system.

 

Development of Sports Apps:
In addition to the medical field, It is also widely used in the sports world. Due to its ability to enhance muscle growth, enhance recovery, and enhance athletic performance, It is used as a stimulant by some athletes to improve their performance and give them a competitive edge. However, the international sports world has strict regulations on the use of doping drugs, and users must abide by relevant regulations and undergo drug testing.

 

Developments in research areas:
The study of It has also been extended to the field of scientific research. Scientists use product to explore its role in areas such as reproductive physiology, neuroscience, and gerontology. These studies help us better understand the biological functions of androgens and the mechanism of action of TIt in various systems.

 

Review of legality and safety:
Because It is a regulated drug, its legality and safety are under intense scrutiny. The laws and regulations of various countries stipulate the scope of its legal use, as well as the rules and restrictions that need to be followed. In addition, potential side effects and risks need to be considered when using It, such as cardiovascular problems, liver damage, hormone dependence, etc. Therefore, the legality and safety assessment of It is an integral part of the research and development process.

 

Summarize:It as a synthetic androgen derivative, has a wide range of applications in medicine, sports and research. Through continuous research and technological advancement, we have gained a deeper understanding of its chemical properties, pharmacological effects, and synthesis methods.However, due to its legal and safety restrictions, users need to strictly abide by relevant regulations and use it in qualified laboratories or medical institutions. With the development of science, we believe that the research on Testosterone isocaproate will be further deepened, bringing us more medical and scientific breakthroughs.

adverse reaction

Testosterone Isocarbonate is an artificially synthesized testosterone ester compound, belonging to the class of androgens and anabolic steroids (AAS). As a derivative of testosterone, it extends the release time of testosterone in the body through esterification and is commonly used in testosterone replacement therapy (TRT) or exercise performance enhancement.

Cardiovascular system adverse reactions

Elevated blood pressure and hypertension

Testosterone Isocaproate may increase blood pressure by increasing erythropoiesis and fluid retention. Long term use may cause persistent hypertension and increase cardiac burden. Research has shown that among users of testosterone replacement therapy (TRT), the incidence of hypertension is significantly higher than that of non users, especially when the dose exceeds the physiological range, the risk is more pronounced.

Abnormal blood lipids

Testosterone esters may lower levels of high-density lipoprotein cholesterol (HDL-C, also known as "good cholesterol") while increasing levels of low-density lipoprotein cholesterol (LDL-C, also known as "bad cholesterol") and triglycerides. This change in blood lipid pattern may accelerate the progression of atherosclerosis and increase the risk of coronary heart disease. For example, a study targeting TRT users found that after use, HDL-C decreased by an average of 15% and LDL-C increased by 10%.

Thrombosis risk

Testosterone may increase the risk of venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), by promoting red blood cell production (erythrocytosis) and altering coagulation factor levels. Symptoms may include swelling, pain, difficulty breathing, or chest pain in the lower limbs, requiring urgent treatment.

Myocardial infarction and stroke risk

Some observational studies suggest that TRT may increase the risk of non fatal myocardial infarction and stroke, especially in elderly men or patients with pre-existing cardiovascular disease. For example, Finkle's study showed that within 90 days of initial TRT prescription, the risk of non fatal myocardial infarction increased by 36% (RR=1.36). However, it should be noted that such studies may be influenced by confounding factors, and the conclusions are still controversial.

 

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