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2-Naphthol Powder CAS 135-19-3
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2-Naphthol Powder CAS 135-19-3

2-Naphthol Powder CAS 135-19-3

Product Code: BM-3-2-059
English Name: 2-Naphthol
CAS No.: 135-19-3
Molecular formula: c10h8o
Molecular weight: 144.17
EINECS No.: 205-182-7
MDL No.:MFCD00004067
Hs code: 28273985
Analysis items: HPLC>99.0%, LC-MS
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Changzhou Factory
Technology service: R&D Dept.-4

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 2-naphthol powder cas 135-19-3 in China. Welcome to wholesale bulk high quality 2-naphthol powder cas 135-19-3 for sale here from our factory. Good service and reasonable price are available.

 

2-Naphthol powder is a white to red plate-like crystal that darkens in color when stored in air for a long time, CAS 135-19-3, Molecular formula C10H8O. Insoluble in cold water, easily soluble in hot water, soluble in ethanol, ether, chloroform, glycerol, and alkaline solutions. Commonly used in the production of tungstic acid, butyric acid, β - naphthol-3-carboxylic acid, and azo dyes. It is also a raw material for rubber anti-aging agents, mineral processing agents, fungicides, mold inhibitors, preservatives, parasite control agents, and insect repellents.

Product Introduction

A variety of downstream ether products of naphthol have the fragrance of orange flower and locust flower, with soft smell, and can be used as a fixative for essence such as soap and toilet water and some spices. Specifically, it includes methyl ether, ethyl ether, butyl ether, and benzyl ether, which can be obtained by reacting them with corresponding alcohols under acidic catalysts, or by reacting them with corresponding sulfates or halogenated hydrocarbons.

Chemical Formula

C10H8O

Exact Mass

144

Molecular Weight

144

m/z

144 (100.0%), 145 (10.8%)

Elemental Analysis

C, 83.31; H, 5.59; O, 11.10

CAS 135-19-3 2-Naphthol | Shaanxi BLOOM Tech Co., Ltd

2-Naphthol | Shaanxi BLOOM Tech Co., Ltd

2-naphthol chemical properties and stability:

1

The toxicology is similar to phenol, and it is a stronger corrosive. It is strongly irritating to the skin. It is easily absorbed through the skin. Toxic to blood circulation and kidney. In addition, it can cause corneal damage. Although the lethal dose is not clear, there are cases of death caused by external application of 3-4g. The production equipment shall be sealed and leak proof, and the splashed on the skin shall be washed in time. The workshop shall be ventilated and the equipment shall be sealed. Operators shall wear protective equipment.

2

It is combustible, and the color becomes darker after long-term storage. It is stable in the air, but the color becomes darker when exposed to sunlight. Heat sublimation, with pungent phenol smell

3

Exist in flue gas.

4

The reaction between aqueous solution and ferric chloride is green.

Manufacture Information

Synthesis of 2-Naphthol powder:
 

1. It is prepared from naphthalene through sulfonation and alkali melting. Sulfonated alkali melting is a widely used production method at home and abroad, but it has serious corrosion, high cost and high biological oxygen consumption in wastewater. The 2-isopropyl naphthalene process developed by cyanamide company of the United States uses naphthalene and propylene as raw materials to produce 2-naphthol and acetone by-product. This process is similar to the process of producing phenol with isopropyl benzene.

 

2. Heat and melt refined naphthalene, add sulfuric acid, and then heat up for sulfonation reaction. When the content of 2-naphthalenesulfonic acid exceeds 66% and the total acidity is 25% to 27%, the reaction is complete, hydrolyzed, and free naphthalene is blown away with steam. Sodium sulfate solution is slowly and evenly added for neutralization reaction until the Congo red test paper no longer appears blue.

 

3. The sulfur dioxide gas generated in the reaction is removed in a timely manner by steam, and the neutralized product is cooled and crystallized. The crystals obtained by suction filtration are washed with 10% saline solution, dried, and then added with molten 98% sodium hydroxide at a temperature of 300-310 ° C. The mixture is stirred and maintained at 320-330 ° C to alkalize sodium 2-naphthalenesulfonate to sodium 2-naphthalenyl alcohol

 

4. Then dilute the alkali melt with hot water and introduce the sulfur dioxide produced by the neutralization reaction. The acidification reaction is carried out at 70-80 ° C until phenolphthalein is colorless.

 

5. The acidified product is placed for layering and then heated to boiling upper liquid. After standing, the water layer is removed. The crude 2-naphthol obtained is first heated and dehydrated, and then distilled under low pressure to obtain pure product.

 

6. Remove 1-naphthol from 2-naphthol by extraction crystallization. Mix 2-naphthol with water in a certain proportion and heat it to 95 ° C. After 2-naphthol is melted, stir the mixture vigorously and quickly cool it to about 85 ° C, cool the crystalline slurry product to room temperature and filter it. Through purity analysis, the content of 1-naphthol is trace.

 

7. Prepared from 2-naphthalene sulfonic acid by alkali melting.

Chemical

Usage

 

2-Naphthol (chemical formula C10H8O), also known as ethylnaphthol, β - naphthol, 2-hydroxynaphthalene, etc., is a white to red plate-like crystal that darkens in color when stored in air for a long time, sublimates upon heating, and has a pungent phenol odor. Its aqueous solution reacts green with ferric chloride and has multiple important uses, playing a key role in multiple fields.

2-Naphthol dye | Shaanxi BLOOM Tech Co., Ltd

Dye field

1. As a dye intermediate
It is an important precursor of organic dyes, especially various azo dyes. In the dye industry, it is one of the most widely used fields. Its downstream derivatives such as 2-hydroxy-3-naphthoic acid and chromophenol AS are widely used as dye intermediates in textile printing and dyeing, leather, papermaking and other fields. Taking tosylate as an example, it is a key precursor for the synthesis of various azo dyes, which can be used to synthesize various dyes such as sunset yellow, acid red 18, temptation red, acid orange 7, acid blue 193, chrome black T.

These dyes endow products with rich colors in industries such as textiles and leather, meeting the coloring needs of different products.

2. Production advantages
It is irreplaceable in dye production. It can undergo specific reactions with other chemicals to generate dye molecules with specific colors and properties. Its unique chemical structure enables the synthesized dyes to have good dyeing performance, such as high dye uptake, bright color, and good color fastness. This makes dyes produced using 2-naphthol competitive in the market and able to meet the quality requirements of different industries for dyes.

2-Naphthol colors | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol pesticicde | Shaanxi BLOOM Tech Co., Ltd

Pesticide field

1. Manufacturing herbicides and plant growth regulators
In agriculture, it can be used to manufacture herbicides such as naphthylamine and plant growth regulators such as 2-naphthoxyacetic acid. Napropylamine is a plant hormone herbicide that has good contact killing activity against annual and perennial weeds such as melon bark, firefly, and cowhide. It can interfere with the physiological metabolic processes of weeds, inhibit their growth and reproduction, and effectively control the harm of weeds to crops. 2-Naphthyloxyacetic acid (BNOA) is a type of plant growth regulator with auxin biological activity, absorbed by leaves and roots, which can promote fruit setting and stimulate fruit enlargement.

It can help farmers optimize the growth process of crops, improve crop yield and quality.

2. Application effect

The use of pesticides 2-naphthol powder by it has significant effects in agricultural production. The use of herbicides can reduce nutrient competition between weeds and crops, improve crop nutrient absorption efficiency, and thus increase crop yield. The application of plant growth regulators can regulate the growth cycle of crops, allowing them to bloom and bear fruit at the appropriate time, improving the quality and marketability of fruits. This is of great significance for ensuring food security and promoting sustainable agricultural development.

2-Naphthol plant | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol medical | Shaanxi BLOOM Tech Co., Ltd

Medical field

1. Synthesize multiple drugs
It has a wide range of applications in the field of medicine and can be used to synthesize various drugs. It can be used to synthesize common nonsteroidal anti-inflammatory drugs such as naproxen and nalbutanone. Naproxen is a PG synthetase inhibitor, which can inhibit prostate synthetase and has significant analgesic and antipyretic effects.

It is often used to relieve mild to moderate pain, such as headache, arthralgia, toothache, etc., and can also be used to treat fever caused by common cold or influenza. Nalbutanone is a prodrug of long-acting nonsteroidal anti-inflammatory drugs, mainly used for symptomatic treatment of acute and chronic osteoarthritis and rheumatoid arthritis. It can alleviate inflammatory reactions, relieve joint pain and swelling, and improve patients' quality of life.

 

2-Naphthol pain | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol drug | Shaanxi BLOOM Tech Co., Ltd

2. Principles of drug synthesis
In the process of drug synthesis, chemical properties enable it to undergo specific reactions with other compounds, forming drug molecules with pharmacological activity. By modifying and altering its molecular structure, drugs with different pharmacological effects and mechanisms of action can be synthesized. For example, in the synthesis of naproxen, a series of chemical reactions are carried out to introduce specific functional groups, thereby endowing the drug with the activity of inhibiting prostate synthase.

3. Market prospects of pharmaceutical grade products
With people's increasing attention to health and environmental protection, the market demand for pharmaceutical grade products will continue to increase. The pharmaceutical industry has extremely high requirements for the quality and safety of drugs. Pharmaceutical grade 2-naphthol, as an important raw material for drug synthesis, is closely related to the market demand and development of the pharmaceutical industry. With the intensification of population aging and the increasing demand for health, the pharmaceutical market will continue to expand, thereby driving the growth of market demand for pharmaceutical grade 2-naphthol.

2-Naphthol pharmaceutical | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol soap | Shaanxi BLOOM Tech Co., Ltd

Spice industry

1. As a fragrance fixative
A variety of downstream ether 2-naphthol powder of naphthol have the fragrance of orange flower and locust flower, with soft smell, and can be used as a fixative for essence such as soap and toilet water and some spices. Specifically, these ether products include methyl ether, ethyl ether, butyl ether, and benzyl ether, which can be obtained by reacting them with corresponding alcohols under acidic catalysts, or by reacting the substance with corresponding sulfates or halogenated hydrocarbons.

Fragrance fixatives play an important role in spices, as they can prolong the fragrance retention time and make the aroma of spices more long-lasting and stable.

2. Application effect
Adding synthetic fragrance fixatives to products such as soap and floral water can continuously emit pleasant aromas during use, improving product quality and user experience. For example, soap containing 2-naphthol ether fixatives will leave a lasting fragrance on the body after bathing, bringing a pleasant feeling. The fragrance fixative in flower dew water can make the mosquito repellent and cool aroma of flower dew more long-lasting, enhancing the effectiveness of product use.

2-Naphthol industry | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol rubber | Shaanxi BLOOM Tech Co., Ltd

Rubber industry

1. Manufacturing rubber anti-aging agents
Can be used for synthesizing rubber anti-aging agents such as DNP. Antioxidant Ding is a universal anti-aging agent used for natural rubber, diene synthetic rubber, chloroprene rubber, and base latex. It has good protective effects against heat, oxygen, bending, and general aging. Antioxidant DNP is one of the important low toxicity antioxidants for rubber and plastic processing, with excellent resistance to heat aging, natural aging, and harmful metals such as copper and manganese. In the production process of rubber products, adding anti-aging agents can delay the aging process of rubber.

Improve the service life and performance of rubber products.

2. Mechanism of action
Rubber will be affected by factors such as heat, oxygen, light, and ozone during storage and use, leading to aging and a decrease in its performance. The anti-aging agent synthesized from 2-naphthol can interact with rubber molecules, inhibit the generation and reaction of free radicals, and thus slow down the aging rate of rubber. For example, antioxidant DNP can react with unsaturated bonds in rubber to form stable chemical bonds, preventing oxygen attack and protecting the structural integrity of rubber molecules.

2-Naphthol heat | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol cosmetics | Shaanxi BLOOM Tech Co., Ltd

Cosmetics field

1. Has multiple functions
It has the effects of whitening, anti-aging, and sun protection, and can be used to prepare cosmetic products such as whitening cream, anti-aging cream, and sunscreen. Its whitening effect may be related to its ability to inhibit the production of melanin, by regulating the metabolism of melanin in the skin, reducing pigmentation, and making the skin fairer. The anti-aging effect may stem from its antioxidant properties, which can eliminate free radicals in the skin, reduce the damage of free radicals to skin cells, and delay skin aging.

Sunscreen can absorb or reflect ultraviolet rays, protecting the skin from UV damage.

2. Application prospects
With the increasing demand for beauty and health, the application prospects in the field of cosmetics are also becoming broader. The cosmetics market has a strong demand for raw materials with multiple functions, and with their unique effects, they are expected to be widely used in cosmetics. However, the application in cosmetics requires strict compliance with relevant regulations and standards to ensure the safety and effectiveness of the product.

2-Naphthol skin | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol reagent | Shaanxi BLOOM Tech Co., Ltd

Other fields

1. As an analytical reagent and absorbent
Can be used as an analytical reagent, ethylene, carbon monoxide absorbent, and fluorescent indicator. In chemical analysis, it can be used as a specific reagent to detect and determine the content of certain substances. As an absorbent for ethylene and carbon monoxide, it can react chemically with these gases to remove impurities from them. As a fluorescent indicator, it can emit fluorescent signals during specific chemical reactions or analytical processes, indicating the degree of reaction or the presence of substances.

2. Chiral synthetic intermediate
2-Naphthol powder is a widely used chiral separating agent and chiral ligand intermediate, widely used in the chiral synthesis of chiral liquid crystals, drugs, fragrances, and pesticides. Chiral synthesis plays an important role in modern chemistry, and many drugs, fragrances, and pesticides have chiral structures. Their different enantiomers may have different biological activities and pharmacological effects. 1,1 '- Bis-2-naphthol can help synthesize compounds with specific chirality in chiral synthesis, improving the purity and activity of the product.

2-Naphthol clinical | Shaanxi BLOOM Tech Co., Ltd
2-Naphthol citrus | Shaanxi BLOOM Tech Co., Ltd

3. Food and feed preservatives
2-Naphthol can be used as a preservative for citrus preservation and feed preservation. China stipulates that it can be used for citrus preservation, with a maximum usage of 0.1g/kg and a residue level not exceeding 70mg/kg; It can also be used for feed preservation. Adding an appropriate amount of 2-naphthol to food and feed can inhibit the growth and reproduction of microorganisms, extend the shelf life of food and feed, and reduce losses caused by microbial contamination. But its use in food and feed requires strict control of dosage to ensure safety.

Frequently Asked Questions
 
 

What is 2-naphthol used for?

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2-Naphthol has several different uses including dyes, pigments, fats, oils, insecticides, pharmaceuticals, perfumes, antiseptics, synthesis of fungicides, and antioxidants for rubber.

Is 2-naphthol an acid or base?

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Weakly acidic

2-naphthol is weakly acidic with a pKa of 9.5. Unlike the other two compounds in the mixture, naphthalene is neutral.

What is the name of the 2-naphthol?

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2-Naphthol, or β-naphthol, is a fluorescent colorless (or occasionally yellow) crystalline solid with the formula C 10H 7OH. It is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring. The naphthols are naphthalene homologues of phenol, but more reactive.

Is 2-naphthol an alcohol?

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Naphthol is not an alcohol. Although both have a functional OH group, the OH group in naphthol is attached directly to the carbon of the benzene ring.

Is 2-naphthol a hazard?

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Hazard statement(s) H302 + H332 Harmful if swallowed or if inhaled H319 Causes serious eye irritation. H400 Very toxic to aquatic life. Precautionary statement(s) P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling.

 

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