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DL-Alanine CAS 302-72-7
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DL-Alanine CAS 302-72-7

DL-Alanine CAS 302-72-7

Product Code: BM-3-2-077
English name: DL Alanine
CAS No.: 302-72-7
Molecular formula: C3H7NO2
Molecular weight: 89.09
EINECS No. 206-126-4
MDL No.:MFCD00064408
Hs code: 28273985
Analysis items: HPLC>99.0%, LC-MS
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Changzhou Factory
Technology service: R&D Dept.-4

DL-Alanine, a chemical, molecular formula C3H7NO2. Colorless to white acicular crystal or crystalline powder, odorless, sweet, soluble in water. It is used as raw material for manufacturing vitamin B6, medical microorganism and biochemical amino acid metabolism. It is mainly used in food processing industry as nutritional supplement and condiment. Second, it is used in the pharmaceutical industry. It has good taste and can enhance the flavoring effect of chemical seasoning.

 

Product Introduction

 

DL-Alanine CAS 302-72-7 | Shaanxi BLOOM Tech Co., Ltd

DL-Alanine CAS 302-72-7 | Shaanxi BLOOM Tech Co., Ltd

Chemical Formula

C3H7NO2

Exact Mass

89.05

Molecular Weight

89.09

m/z

89.05 (100.0%), 90.05 (3.2%)

Elemental Analysis

C, 40.44; H, 7.92; N, 15.72; O, 35.91

Usage

 

DL-Alanine has diverse applications ranging from nanoparticle production to use as a sweetening agent, and it plays a crucial role in the glucose-alanine cycle. Its ability to chelate transition metals also makes it a valuable tool in research. With further research and development, which may find even more applications in pharmaceutical and biomedical fields.

 

Nanoparticle Production

 

Its role as a reducing and capping agent in the production of nanoparticles, specifically when used in conjunction with aqueous silver nitrate, underscores its significance in nanotechnology and materials science.

  • In the process of synthesizing silver nanoparticles, it acts as a multifaceted agent. Firstly, its reducing properties enable it to convert silver ions (Ag⁺) present in the aqueous silver nitrate solution into silver atoms (Ag⁰). This reduction is crucial for the nucleation and growth of silver nanoparticles.
  • Secondly, it also functions as a capping agent. This means it adsorbs onto the surface of the newly formed silver nanoparticles, stabilizing them and preventing agglomeration. The capping action is vital for controlling the size, shape, and dispersion of the nanoparticles, which in turn affects their properties and potential applications.

The use in this process offers several advantages. It is relatively inexpensive and easy to handle, making it a cost-effective choice for large-scale production of silver nanoparticles. Furthermore, the mild reaction conditions required for its reduction and capping actions make it a suitable choice for synthesizing nanoparticles with well-defined properties.

The resulting silver nanoparticles have a wide range of applications in nanotechnology and materials science. They can be used as catalysts in chemical reactions, as sensors for detecting various analytes, and as conductive materials in electronic devices. The unique optical, electrical, and magnetic properties of silver nanoparticles also make them promising candidates for use in biomedicine, energy storage, and environmental remediation.

In conclusion, its dual role as a reducing and capping agent in the production of silver nanoparticles makes it a crucial component in nanotechnology and materials science. Its ability to stabilize and control the properties of the nanoparticles enables their use in a wide range of applications, contributing to advancements in these fields.

 

DL-Alanine CAS 302-72-7 Applications | Shaanxi BLOOM Tech Co., Ltd

DL-Alanine CAS 302-72-7 Applications | Shaanxi BLOOM Tech Co., Ltd

Sweetening Agent

 

It possesses a slightly sweet taste, although it is generally less sweet than common artificial sweeteners like sodium saccharin or aspartame. However, its classification as a sweetener, alongside other amino acids like glycine, suggests that it could be explored as a natural alternative or component in blends of sweeteners.

In the food and beverage industry, the demand for natural and healthier sweeteners is on the rise. Consumers are increasingly looking for alternatives to sugar and artificial sweeteners due to concerns about health, weight management, and potential side effects. Being an amino acid, could potentially appeal to this market segment as a more natural option.

Moreover, its use as a sweetener could be particularly interesting in specific food products where its additional nutritional benefits or functional properties might be leveraged. For instance, its role in energy metabolism through the glucose-alanine cycle could make it an attractive ingredient in sports nutrition products or energy drinks.

 

Glucose-Alanine Cycle

 

It plays a key role in the glucose-alanine cycle between tissues and the liver. This cycle is important for energy metabolism and maintaining glucose levels in the body.

 

Energy metabolism

 

 

Skeletal muscles use glucose to generate energy through glycolysis and produce pyruvate. When sugar supply is insufficient, skeletal muscles can obtain amino acids (such as alanine) by breaking down proteins and converting them into pyruvate. Pyruvate then enters the tricarboxylic acid cycle and releases energy for skeletal muscles to use.

 

Maintaining blood sugar levels

 

 

After alanine is transported to the liver through the blood, it is converted into glucose through gluconeogenesis and then released into the blood to maintain blood sugar stability. This process is essential to prevent hypoglycemia and ensure that the brain and other organs have an adequate supply of glucose.

 

Transition Metal Chelation Research

 

It can be used to study the chelation of transition metals such as Cu, Zn, and Cd. This makes it a valuable tool in research related to metal ion biology, toxicology, and environmental science.

Metal ion chelation research

The carboxyl and amino functional groups can form stable chelates with metal ions. This chelation not only helps to understand the transport, storage and detoxification mechanisms of metal ions in organisms, but also reveals how metal ions interact with biological molecules.

01

Metal ion biology research

In the field of biology, metal ions such as copper, zinc and cadmium play an important role. They participate in the catalytic reactions of various enzymes, exist as structural components in proteins, and affect cell signal transduction and metabolic processes. The chelation with these metal ions provides a means to study the functions and regulatory mechanisms of these metal ions in organisms.

02

Metal ion toxicology research

Some metal ions such as cadmium are toxic to the human body and can cause health problems such as heavy metal poisoning. The chelation with these toxic metal ions provides an important experimental model for studying their toxicity mechanisms, developing detoxification methods and evaluating potential health risks.

03

Environmental Science Research

In the field of environmental science, the chelation can be used to evaluate the migration, transformation and bioavailability of metal ions in the environment. This is of great significance for understanding the circulation of metal ions in ecosystems, predicting their impact on the environment and organisms, and formulating environmental protection strategies.

04

 

Pharmaceutical and Biomedical Applications

 

As an orally active amino acid, DL-Alanine may have potential applications in pharmaceutical and biomedical fields. However, specific uses in these areas may require further research and development.

 

Manufacture Information

 

Synthesis method

 

  • Acetaldehyde reacts with hydrocyanic acid to produce cyanohydrin, and then reacts with ammonia to obtain aminonitrile, and then hydrolyzes to produce sodium aminopropionate under alkaline conditions. Alanine is obtained through ion exchange.
  • Mix 2-bromopropionic acid, ammonium carbonate and concentrated ammonia water for reaction. Add water for heating and refluxing, evaporate the reaction solution to dryness, and then soak and filter it with ethanol. The filter cake is dissolved in distilled water, boiled, decolorized by activated carbon, added with 95% ethanol to the filtrate, cooled, crystallized, and dried to obtain alanine.
  • Slowly add propionic acid to phosphorus trichloride, slowly add bromine at 78~83 ℃, keep it warm for 1h after adding, and then heat it to 105 ℃ to volatilize most of the hydrogen bromide. Then, remove the hydrogen bromide by vacuum distillation, and the obtained bromopropionic acid is ready for use. After mixing sodium bicarbonate, ammonium hydroxide and water, slowly add the above bromopropionic acid with a control temperature of 30~40 ℃. After addition, keep the temperature for 16h, raise the temperature to 90~100 ℃ until the ammonia volatilizes completely, then concentrate until crystallization occurs, pour it into methanol, cool and filter to obtain crystallization. Dissolve the crude product crystallization with water, add active carbon to decolorize, filter, pour the filtrate into ethanol to crystallize, and then obtain the finished product.

Chemical | Shaanxi BLOOM Tech Co., Ltd

 

DL-Alanine, also known as racemic alanine, is a non-essential amino acid that exists in both its D- and L-enantiomeric forms. It is a simple amino acid with a single carboxyl group (-COOH) and an amino group (-NH2) connected to a central carbon atom, which also bears a methyl group (-CH3). This molecular structure grants it unique chemical and biological properties.

Unlike other amino acids that are predominantly found in their L-form in natural proteins, it does not exhibit chirality-specific functions in biological systems. As a racemic mixture, it can be utilized by organisms in either enantiomeric form, making it versatile in various applications.

It plays a crucial role in biochemical processes, such as serving as a precursor for synthesizing other amino acids, vitamins, and coenzymes. It is also involved in energy metabolism and muscle protein synthesis. In the pharmaceutical industry, it serves as an excipient, enhancing the stability and solubility of drugs.

Moreover, It finds applications in nutritional supplements, where it contributes to maintaining nitrogen balance and supporting muscle growth. Its use in cosmetics aims to improve skin hydration and elasticity. Additionally, it serves as a key component in the synthesis of peptides and proteins for research purposes.

In summary, with its balanced enantiomeric composition, offers a wide range of applications across different fields, from pharmaceuticals and nutrition to cosmetics and biochemical research. Its fundamental role in biochemical processes underscores its importance in various industries.

 

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