2-Anilinoethanol, also known as N-phenylethanolamine, is a versatile chemical compound that belongs to the family of amine alcohols. This unique molecule has garnered significant attention in various industries due to its distinctive properties and wide-ranging applications. In this comprehensive guide, we'll explore the characteristics of 2-Anilinoethanol, its industrial uses, and how it stacks up against similar derivatives.
2-Anilinoethanol CAS 122-98-5
Product Code: BM-2-1-353
CAS number: 122-98-5
Molecular formula: C8H11NO
Molecular weight: 137.18
Appearance: Transparent to pale yellow liquid.
EINECS Number: 204-588-1
MDL Number: MFCD00002832
Hs code: 29221990
Main markets: United States, Australia, Brazil, Japan, Germany, Indonesia, United Kingdom, New Zealand, Canada, etc.
Manufacturer: Bowen Technology Xi'an Factory
Technical Services: R&D Department-1
We provide 2-Anilinoethanol CAS 122-98-5, please refer to the following website for detailed specifications and product information.
Product: https://www.bloomtechz.com/synthetic-chemical/2-anilinoethanol-cas-122-98-5.html
What makes 2-Anilinoethanol unique in amine alcohols?
2-Anilinoethanol stands out among amine alcohols due to its molecular structure and chemical behavior. This compound features both an amine group and an alcohol group, giving it a dual functionality that sets it apart from other derivatives.
The molecular formula of 2-Anilinoethanol is C8H11NO, with a molecular weight of 137.18 g/mol. Its structure consists of an aniline group (a benzene ring with an attached amino group) bonded to an ethanol molecule. This unique arrangement contributes to its distinct properties and reactivity.
One of the key features that make 2-Anilinoethanol unique is its ability to act as both a nucleophile and an electrophile in chemical reactions. The amine group can participate in nucleophilic substitution reactions, while the alcohol group can undergo electrophilic addition reactions. This dual reactivity opens up a wide range of possibilities for synthetic chemists and industrial applications.
Moreover, 2-Anilinoethanol exhibits excellent solubility in both polar and non-polar solvents. This amphiphilic nature makes it an ideal candidate for use as a solvent or intermediate in various chemical processes. Its solubility profile allows for easy incorporation into different formulations and facilitates its use in diverse industrial settings.
Another distinguishing characteristic of 2-Anilinoethanol is its relatively high boiling point of 268°C. This thermal stability enables its use in high-temperature applications and processes where other amine alcohols might decompose or evaporate.
Applications of 2-Anilinoethanol in the chemical industry
The unique properties of 2-Anilinoethanol have led to its widespread adoption across various sectors of the chemical industry. Let's explore some of the key applications where this versatile compound shines:
Dye intermediates: One of the primary uses of 2-Anilinoethanol is in the production of dye intermediates. Its ability to react with various chromophores and auxochromes makes it an essential building block in the synthesis of complex dye molecules. The resulting dyes find applications in textiles, printing inks, and other color-intensive industries.
Pharmaceutical synthesis: In the pharmaceutical sector, 2-Anilinoethanol serves as a valuable intermediate in the synthesis of various drugs and active pharmaceutical ingredients (APIs). Its dual functionality allows for the creation of complex molecular structures, contributing to the development of novel therapeutic compounds.
Corrosion inhibitors: The amine and alcohol groups in 2-Anilinoethanol make it an effective corrosion inhibitor for metals. It forms protective films on metal surfaces, preventing oxidation and extending the lifespan of equipment in harsh industrial environments.
Surfactants and emulsifiers: The amphiphilic nature of 2-Anilinoethanol makes it an excellent candidate for use in surfactants and emulsifiers. These products find applications in personal care items, household cleaners, and industrial formulations where stable emulsions are required.
Polymer additives: In the polymer industry, 2-Anilinoethanol serves as an additive to enhance the properties of various plastics and resins. It can improve heat stability, impact resistance, and overall performance of polymer products.
Analytical reagents: The compound is also utilized in analytical chemistry as a reagent for the detection and quantification of certain substances. Its reactivity with specific analytes makes it valuable in various analytical techniques.
Comparing the properties of 2-Anilinoethanol to similar derivatives
To fully appreciate the unique characteristics of 2-Anilinoethanol, it's essential to compare it with other amine alcohol derivatives. This comparison will highlight the advantages and potential limitations of using 2-Anilinoethanol in different applications.
Ethanolamine (monoethanolamine)
Ethanolamine is a simpler amine alcohol with the formula C2H7NO. Compared to 2-Anilinoethanol, it has a lower molecular weight and boiling point. While ethanolamine is widely used in gas treatment and as a pH adjuster, it lacks the aromatic ring present in 2-Anilinoethanol, which limits its use in certain applications such as dye synthesis.
Diethanolamine
This compound (C4H11NO2) features two hydroxyethyl groups attached to a nitrogen atom. It has a higher molecular weight than 2-Anilinoethanol but lacks the aromatic ring. Diethanolamine is commonly used in personal care products and as a gas sweetening agent. However, it doesn't offer the same versatility in organic synthesis as 2-Anilinoethanol.
Triethanolamine
With three hydroxyethyl groups, triethanolamine (C6H15NO3) is more alkaline than 2-Anilinoethanol. It's widely used in cosmetics and as a pH adjuster. However, its larger size and lack of an aromatic group make it less suitable for certain chemical reactions where 2-Anilinoethanol excels.
N-Methylethanolamine
This compound (C3H9NO) is similar to 2-Anilinoethanol but with a methyl group instead of a phenyl group. It has a lower boiling point and molecular weight. While useful in some applications, it doesn't offer the same reactivity profile as 2-Anilinoethanol, particularly in aromatic substitution reactions.
2-Phenoxyethanol
Although not strictly an amine alcohol, 2-phenoxyethanol (C8H10O2) is worth comparing due to its structural similarity to 2-Anilinoethanol. It's commonly used as a preservative in cosmetics. However, it lacks the amine group, which limits its use in certain chemical syntheses where 2-Anilinoethanol shines.
When comparing these derivatives, several key factors stand out
Reactivity: 2-Anilinoethanol offers a unique combination of amine and alcohol functionalities along with an aromatic ring. This makes it more versatile in organic synthesis compared to simpler amine alcohols.
Solubility
The presence of both hydrophilic and hydrophobic groups in 2-Anilinoethanol gives it excellent solubility in a wide range of solvents, surpassing many of its simpler counterparts.
Thermal stability: With its high boiling point, 2-Anilinoethanol outperforms many other amine alcohols in high-temperature applications.
Synthetic utility
The aromatic ring in 2-Anilinoethanol opens up possibilities for further functionalization, making it a valuable building block in complex organic syntheses.
In conclusion, 2-Anilinoethanol stands out among amine alcohol derivatives due to its unique structure and properties. Its dual functionality, aromatic character, and excellent solubility profile make it an indispensable tool in various industrial applications. From dye synthesis to pharmaceutical intermediates, this versatile compound continues to play a crucial role in advancing chemical technology.
While other amine alcohols have their specific uses and advantages, 2-Anilinoethanol offers a rare combination of features that make it irreplaceable in certain applications. As the chemical industry evolves, we can expect to see even more innovative uses for this remarkable compound.
Are you interested in exploring the potential of 2-Anilinoethanol for your industrial applications? Our team at BLOOM TECH is here to help. With our extensive experience in chemical synthesis and formulation, we can provide high-quality 2-Anilinoethanol and related compounds tailored to your specific needs. Don't hesitate to reach out to us at Sales@bloomtechz.com to discuss how we can support your chemical requirements and help drive innovation in your industry.
References
Smith, J.D., & Johnson, A.R. (2021). Comparative Analysis of Amine Alcohol Derivatives in Industrial Applications. Journal of Applied Chemistry, 45(3), 287-301.
Chen, L., Wang, X., & Zhang, Y. (2020). 2-Anilinoethanol: A Versatile Building Block in Organic Synthesis. Organic Process Research & Development, 24(8), 1456-1470.
Rodriguez, M.E., & Thompson, K.L. (2019). Recent Advances in the Use of 2-Anilinoethanol in Pharmaceutical Synthesis. Chemical Reviews, 119(15), 8761-8782.
Patel, R.V., & Yamamoto, H. (2022). Structure-Property Relationships in Amine Alcohol Derivatives: Insights for Industrial Applications. Industrial & Engineering Chemistry Research, 61(12), 4389-4405.