Tetrahydrobiopterin(BH4)Powder,Tetrahydrobiopterin powder is a naturally occurring nutrient with multiple important physiological functions. It usually needs to be stored at -20 ° C and appears as a white to pale yellow powder that is easily soluble in water. It is also a coenzyme of multiple enzymes and participates in various biosynthetic processes. It is a coenzyme of aromatic amino acid hydroxylases (including phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylase) and an essential cofactor of nitric oxide synthase (including endothelial, neuronal, and inducible nitric oxide synthase). BH4 is involved in the biosynthesis of substances such as serotonin, dopamine, norepinephrine, adrenaline, melatonin, and nitric oxide, which play important roles in neurotransmission, cardiovascular function, and immune regulation. BH4 deficiency is an autosomal inherited disease and one of the rare diseases. This disease mainly causes damage to the human nervous system, leading to symptoms such as intellectual disability and epilepsy in children. In addition, BH4 deficiency may also lead to the occurrence of phenylketonuria (PKU), where long-term high concentrations of phenylalanine in the patient's blood can cause severe neurological damage. Research has shown that BH4 plays an important role in cardiovascular protection. BH4 deficiency may lead to changes in cardiovascular diseases such as endothelial dysfunction and hypertension. Supplementing with BH4 can improve myocardial function, inhibit myocardial fibrosis, improve ventricular dysfunction, and prevent injury caused by ischemia-reperfusion.
Tetrahydrobiopterin (BH4) Powder CAS 17528-72-2
Product Code: BM-2-5-032
Name: Tetrahydrobiopterin (Short name: BH4) powder
CAS Number: 17528-72-2
Molecular formula: C9H15N5O3
Molecular weight: 241.25
Appearance: A white to pale yellow crystalline solid
Package: Design the package as the MSDS/TSD
Quality: HNMR, USP, HPLC>99.0%,
Producer: BLOOM Weinan polit Factory
Technology R&D Dept.: Department-4
Usage: Science researching only
Main market: 10-20kg per batch to Japan pharmaceutical company
We provide Tetrahydrobiopterin (BH4) Powder CAS 17528-72-2, please refer to the following website for detailed specifications and product information.
What is Tetrahydrobiopterin (BH4) Powder used for?
Tetrahydrobiopterin (BH4) Powder is a natural nutrient with multiple important physiological functions. The following is a detailed explanation of its purpose:
BH4 deficiency is an autosomal inherited disease in which the synthesis or regeneration ability of BH4 in the patient's body is impaired, leading to a series of neurological symptoms such as intellectual disability and epilepsy. BH4 supplementation therapy is one of the effective treatment methods for this type of disease, which can restore the level of BH4 in the patient's body through exogenous supplementation of BH4, thereby improving neurological symptoms. Phenylketonuria (PKU) is a genetic disorder caused by a deficiency of phenylalanine hydroxylase. BH4, as a coenzyme of phenylalanine hydroxylase, its deficiency may also lead to the occurrence of PKU. Therefore, BH4 supplementation therapy has also been used in the treatment of PKU to improve patients' metabolic status and neurological symptoms.
Application in disease treatment
BH4 plays an important role in cardiovascular protection. Research has shown that BH4 can inhibit myocardial fibrosis, improve ventricular dysfunction, and prevent injury caused by ischemia-reperfusion. Therefore, BH4 is used to treat some cardiovascular diseases, such as heart failure, myocardial ischemia, etc. BH4 also participates in the synthesis and regulation of nitric oxide, which has the effect of dilating blood vessels and lowering blood pressure. Therefore, supplementation with BH4 may also contribute to the treatment of hypertension. BH4, as a key coenzyme for neurotransmitter synthesis, its deficiency may lead to the occurrence of neurological diseases. Therefore, BH4 supplementation therapy has also been used in the treatment of some neurological diseases, such as Parkinson's disease, Alzheimer's disease, etc. However, these applications are still in the research stage and have not yet been widely applied in clinical practice.
BH4 has broad application value in biomedical research. It is not only a key coenzyme in various biosynthetic processes, but also an important research object for the pathogenesis and therapeutic targets of various diseases.
BH4 is involved in various biosynthetic processes, such as the synthesis of neurotransmitters, hormones, and nitric oxide. These biosynthetic processes play important roles in the growth, development, and metabolism of organisms. Therefore, BH4 has broad application value in biosynthesis research and can be used to study the regulatory mechanisms and influencing factors of these biosynthesis processes. For example, BH4 deficiency may lead to endothelial dysfunction and the occurrence of cardiovascular diseases.
Application in Biomedical Research
By studying the function and mechanism of BH4 in endothelial cells, we can gain a deeper understanding of the pathogenesis of endothelial dysfunction and provide new targets and methods for the treatment of cardiovascular diseases. As one of the effective targets for the treatment of various diseases, it has broad prospects for drug development. By developing drugs or treatment methods targeting BH4, new options can be provided for the treatment of various diseases. For example, there has been some progress in the development of drugs targeting BH4 deficiency. Some drugs can treat BH4 deficiency by increasing the level of BH4 in the patient's body or improving the synthesis and regeneration ability of BH4. In addition, drug development for the therapeutic effects of BH4 in cardiovascular and neurological diseases is also underway.
Tetrahydrobiopterin (BH4) Powder, as a natural nutrient, also has extensive application value in the fields of nutrition and health. It can be added as a dietary supplement to food or beverages to provide additional nutritional support. Especially for those who need to increase BH4 intake, such as BH4 deficiency patients or those who need to improve neurological function, BH4 dietary supplements may be an effective nutritional support method. It can also be added to functional foods to enhance their health benefits. For example, some functional beverages or health supplements may add BH4 to provide additional energy support or improve neurological function.
Application in the field of nutrition and health
However, it should be noted that the amount and safety of BH4 added in food need to be rigorously evaluated and regulated. It also has certain application value in health management and disease prevention. By monitoring the levels of BH4 in the body and taking corresponding intervention measures, the occurrence and development of diseases related to BH4 deficiency can be prevented. For example, for high-risk individuals with BH4 deficiency, regular BH4 level testing and corresponding nutritional interventions may help prevent the occurrence of the disease.
Conclusion
Tetrahydrobiopterin (BH4) Powder, as a natural nutrient with multiple important physiological functions, has extensive application value in various fields such as biosynthesis, disease treatment, biomedical research, nutrition and health. However, its application prospects also face some challenges and limitations. In the future, with in-depth research on the physiological functions and disease treatment mechanisms of BH4, as well as continuous improvement and enhancement of production technology, the application fields of BH4 will be broader, bringing more breakthroughs and progress to the fields of medicine and nutrition and health.