Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of nitenpyram tablets in China. Welcome to wholesale bulk high quality nitenpyram tablets for sale here from our factory. Good service and reasonable price are available.
The generic name for Nitenpyram Tablets is Imidacloprid Tablets, and its trade names include Capstar ®, Nope Star ® Wait. It is an efficient and safe pet insecticide that quickly kills adult fleas and effectively alleviates discomfort caused by flea parasitism in pets. This drug is an anthelmintic for pets (dogs, cats), mainly targeting flea infections. Its mechanism of action is clear, its pharmacokinetic properties are good, and adverse reactions are rare. However, strict adherence to dosage guidelines is necessary during use, avoiding long-term continuous use, and combining environmental management for comprehensive prevention and control.

The dosage form of this product is tablets, and the main specifications include:
11.4mg specification: Suitable for cats and small dogs weighing 1-11 kilograms.
57mg specification: suitable for dogs weighing 11.1 kg to 57 kg.
57mg dual pack: suitable for dogs weighing over 57kg.
Packaging: Common packaging specifications are 6 pieces/box or 60 pieces/box.
Storage conditions: It should be stored in a light shielded and sealed manner, with a temperature not exceeding 25 ° C to ensure drug stability.
Our product




Additional information of chemical compound:
| Product Name | Nitenpyram Tablets | Nitenpyram Powder |
| Product Type | Tablets | Powder |
| Product Purity | HPLC≥99.0% | ≥99% |
| Product Specifications | Customizable | Customizable |
| Product Package | Customizable | Customizable |
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Ceftiofur+. COA
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Certificate of Analysis |
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Compound name |
Nitenpyram | |
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CAS No. |
150824-47-8 | |
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Grade |
Pharmaceutical grade | |
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Quantity |
Customized | |
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Packaging standard |
Customized | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
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Lot No. |
20250109001 |
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MFG |
Jan 12th 2025 |
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EXP |
Jan 8th 2029 |
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Structure |
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| TEST STANDARD | GB/T24768-2009 Industry. Stnndard | |
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Item |
Enterprise standard |
Analysis result |
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Appearance |
White or almost white powder |
Conformed |
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Water content |
≤4.5% |
0.30% |
| Loss on drying |
≤1.0% |
0.15% |
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Heavy Metals |
Pb≤0.5ppm |
N.D. |
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As≤0.5ppm |
N.D. | |
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Hg≤0.5ppm |
N.D. | |
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Cd≤0.5ppm |
N.D. | |
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Purity (HPLC) |
≥99.0% |
99.5% |
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Single impurity |
<0.8% |
0.48% |
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Residue on ignition |
<0.20% |
0.064% |
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Total microbial count |
≤750cfu/g |
80 |
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E. Coli |
≤2MPN/g |
N.D. |
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Salmonella |
N.D. | N.D. |
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Ethanol (by GC) |
≤5000ppm |
400ppm |
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Storage |
Store in a sealed, dark and dry place at-20 degrees |
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Detailed explanation of indications
Nitenpyram Tablets (product name such as Capstar) ®, Nope Star ®) It is an efficient deworming drug for flea infections in pets (dogs, cats). Its core component, Nitenpyram, belongs to the neonicotinoid insecticide class and exerts its insecticidal effect by interfering with the nicotinic acetylcholine receptor (nAChR) in the insect nervous system. This medication is suitable for the following scenarios:
1. Acute flea infection
Symptoms: Pets may experience frequent scratching, redness and swelling of the skin, hair loss, and residual black flea feces (commonly known as "flea dust"), indicating that fleas have parasitized in large numbers.
Treatment needs: Nitenpyram can quickly kill adult fleas, usually taking effect within 30 minutes after medication, with a killing rate of over 90% within 6 hours.
2. Prevention of Flea Infection
High risk environment: Pets frequently come into contact with outdoor environments (such as parks, grasslands), multi pet households or shelters, and are susceptible to flea infections.
Prevention strategy: Regular use of Nitenpyram (such as once a month) can reduce the risk of flea infection, especially for pets that are intolerant to other long-acting deworming drugs.
3. Preoperative deworming
Surgical requirements: When pets need to undergo surgery (such as sterilization or orthopedic surgery), preoperative deworming can prevent fleas from spreading to the environment or humans during postoperative care.
Recommended plan: Use Nitenpyram within 24 hours before surgery to ensure that there are no adult fleas on the pet's body on the day of surgery.
4. Travel or shelter management
Travel scenario: When traveling with pets, the risk of flea infection may increase due to environmental changes such as hotels and transportation.
Shelter management: Newly arrived pets in shelters must be immediately dewormed to prevent fleas from spreading in the community.
Usage and Dosage Guide
The usage and dosage of Nitenpyram should be adjusted according to the pet's weight and the severity of infection, as follows:

1. Dose selection
Pet type, weight range, specifications, single dose, maximum daily dose
Cats and small dogs, 1-11 kg, 11.4mg, 1 tablet, 1 tablet
Medium sized dogs 11.1-57 kg, 57mg, 1 tablet, 1 tablet
Large dogs weighing over 57 kg, 57mg, 2 tablets, 2 tablets
matters needing attention:
Dogs weighing over 57 kilograms need to use 2 tablets of 57mg medication instead of a single high dose to ensure even distribution of the medication.
Pregnant or lactating pets should be used under veterinary guidance due to limited safety data.
2. Administration method
Direct feeding: Place the pill at the back of the pet's tongue and close the mouth until swallowed.
Mixed food: Crush the pills and mix them into wet food or canned food to ensure complete ingestion by pets.
matters needing attention:
Avoid taking with dairy products or high-fat foods as it may affect drug absorption.
Avoid vigorous exercise within 30 minutes after medication to prevent vomiting and medication failure.
3. Medication frequency
Mild infection: A single dose of medication is sufficient, and the flea killing effect can last for 24-48 hours.
Severe infection: Take medication once a day for 3-7 consecutive days until the fleas are completely cleared.
Preventive medication: once a month or adjusted according to environmental exposure risks.
matters needing attention:
Continuous use for no more than 7 days may increase the risk of drug resistance.
When fleas reappear, medication can be repeated, but at least 24 hours should be allowed between each use.
4. Handling of Special Situations
Flea eggs and larvae: Nitenpyram Tablets has no effect on flea eggs or larvae, so it needs to be comprehensively controlled in combination with environmental insect repellents (such as spray containing propyl ether).
Multi pet households: All pets need to be dewormed simultaneously to prevent cross infection.
Environmental management: During medication, pet bedding, carpets, and furniture should be cleaned, and flea eggs and larvae should be removed using a vacuum cleaner.

Pharmacokinetics
Absorption and Distribution
Absorption: Rapid absorption after oral administration, reaching peak blood drug concentration within 30 minutes.
Distribution: Widely distributed in pet blood, flea bites enter their bodies through blood.
Metabolism and excretion
Metabolism: It is mainly metabolized by the liver cytochrome P450 enzyme system, and the metabolites are excreted by the kidneys.
Half life: The half-life in dogs and cats is relatively short (about 4-6 hours), and it needs to be repeated daily or every other day to maintain efficacy.
Special populations (pets)
Elderly pets: No need to adjust dosage, but liver and kidney function needs to be monitored.
Pregnant/lactating pets: Safety is not fully understood, it is recommended to weigh the pros and cons before use.
Pets with liver and kidney dysfunction: use with caution, may require reducing dosage or extending dosing intervals.
Clinical Application and Guidelines
Clinical Application
Acute flea infection: As a first-line medication, it rapidly reduces the number of fleas.
Preoperative preparation: Remove fleas before surgery to reduce the risk of postoperative infection.
Travel or shelter: Used for emergency deworming of newly arrived pets or after environmental exposure.
Expert Consensus and Guidelines
World Small Animal Veterinary Association (WSAVA): Nitenpyram is recommended as a quick acting drug for adult flea control, but it needs to be combined with environmental insect repellent (such as spray, flea collar) for comprehensive prevention and control.
The American Association of Animal Hospitals (AAHA) recommends monthly use of long-acting deworming drugs (such as Celastrol) as a baseline regimen, and Nitenpyram for supplemental treatment of acute infections.
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Patient education (pet owner)
Pre medication consultation
Inform the veterinarian of the complete medical history of the pet, including allergy history, chronic diseases, and medication history.
Confirm the weight of the pet and choose the appropriate size.
01
Observation after medication
Monitor pets for adverse reactions such as vomiting, diarrhea, and abnormal behavior.
If the symptoms persist or worsen, stop taking the medication immediately and seek medical attention.
02
Long term management
Flea prevention and control should be combined with environmental management (such as regular cleaning of pet bedding, use of flea spray).
Follow veterinary advice and develop personalized deworming plans.
03
Handling of Special Situations
Accidental ingestion: If pets or children accidentally ingest, immediately contact a poison control center or seek medical attention.
Overdosing on medication: Excessive sedation and ataxia may occur, requiring supportive treatment.
04
Market and Regulatory Information
Listing Status
Nitenpyram Tablets have been launched in multiple countries and regions around the world, including the United States, Europe, Japan, China, and others. The product names may vary slightly in different regions (such as Capstar) ®, Nope Star ®).
Regulatory Status
FDA: Classified as over-the-counter (OTC) drugs, but some countries (such as China) require purchase with a veterinary prescription.
EMA: Approved for use in dogs and cats, with recognized safety and efficacy.
Generic drugs and bioequivalence
There are various generic drugs on the market, and their bioequivalence needs to be verified through in vitro and in vivo studies. Suggest selecting products that have undergone consistency evaluation.
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