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Butylparaben powder , also known as butyl p-hydroxybenzoate, CAS 94-26-8, The molecular formula C11H14O3 is a white crystal with a slight special odor and a stinging sensation when tasted. Slightly soluble in water, easily soluble in organic solvents such as ethanol, propylene glycol, ether, chloroform, etc. Can be used as an organic synthesis intermediate, as a preservative and preservative additive for pharmaceuticals, food, cosmetics, films, and high-end products. In addition to being used as a preservative, it can also be used as a processing aid in the foodstuff industry.

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Chemical Formula |
C11H14O3 |
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Exact Mass |
194 |
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Molecular Weight |
194 |
|
m/z |
194 (100.0%), 195 (11.9%) |
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Elemental Analysis |
C, 68.02; H, 7.27; O, 24.71 |
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For example, in the processing of some foods, it can act as a stabilizer, emulsifier, etc., improving the processing performance and quality of the foodstuff. It has multiple uses in the food industry, including foodstuff preservation and preservation, improving foodstuff quality, functions in specific food processing, synergistic effects with other ingredients in food, specific application methods in specific foodstuff systems, and compliance with regulatory standards.

Butylparaben powder, also known as butyl paraben, is an important food preservative with wide applications in the food industry.
Food preservation and preservation
(1) Extend the shelf life of food
As a broad-spectrum and highly effective food preservative, it can significantly extend the shelf life of food. It prevents food spoilage by inhibiting the growth of microorganisms such as bacteria, yeast, and mold that are prone to spoilage of food and beverages. In the process of food processing and storage, the growth and reproduction of microorganisms is one of the main reasons for food spoilage. The addition of this substance can effectively inhibit the activity of microorganisms, thereby extending the shelf life of food.
(2) Antibacterial mechanism and advantages
Its antibacterial activity mainly depends on its molecular state, and the hydroxyl groups within its molecules have been esterified and no longer ionized, so it has good antibacterial effects in the pH range of 3-8. Benzoic aci and sorbic aci are both acidic preservatives, and their antibacterial effect is poor in products with pH>5.5. In contrast, it has a wider range of applications and can exert good antibacterial effects in different foodstuff systems.
(3) Suitable for multiple types of food
Widely used in various fields such as soy sauce, vinegar and other seasonings, pickled products, baked goods, soy sauce products, beverages, yellow wine, and fruit and vegetable preservation.

In soy sauce, vinegar and other seasonings, it can prevent problems such as mold and spoilage during storage, and maintain their original flavor and quality. In pickled products, it can inhibit the growth of microorganisms and prolong the storage time of pickled products. In baked goods and soy sauce products, it can prevent foodstuff from being contaminated by microorganisms during storage and sales, ensuring the safety and quality of foodstuff. In beverages, it can prevent the beverage from spoiling, maintain the taste and nutritional content of the beverage. In Huangjiu, it can inhibit the growth of microorganisms and prevent Huangjiu from spoiling. In fruit and vegetable preservation, it can extend the shelf life of fruits and vegetables and reduce their loss.
Improve food quality
(1) Maintain protein stability
In various acidic environments, butylparaben powder can maintain protein stability and suspension, unaffected by time and temperature. In some acidic foodstuffs, proteins are prone to denaturation, precipitation, and other problems, which affect the quality and taste of the food. Its addition can stabilize the structure of proteins, prevent adverse reactions, and maintain the quality and taste of food.
(2) Strong emulsifying property
Can emulsify protein and fat, forming a stable emulsion solution.


In some dairy products, beverages, and other foods, the emulsification performance directly affects the taste and stability of the foodstuff. Its emulsifying properties can evenly disperse protein and fat in foodstuff, forming a stable emulsifying system and improving the taste and quality of foodstuff.
(3) Enhance taste
It has the characteristics of low viscosity and refreshing taste, especially better palatability in acidic beverages such as yogurt and lactic aci drinks. Adding nipagin butyl ester during foodstuff processing can improve the taste of foodstuff and make it easier for consumers to accept.
Functions in specific food processing
(1) Fried food and pastry processing
When making fried foodstuffs or pastries, adding an appropriate amount of butyl nipagin not only has a nutritional strengthening effect but also prevents oil oxidation and foodstuff discoloration, improving the sensory quality of the product. Fried foods and pastries are prone to oil oxidation during storage, leading to food spoilage and odor. Its antioxidant effect can slow down the oxidation rate of oils and maintain the freshness and taste of food.


At the same time, it can also prevent color changes in foodstuff during processing and improve the appearance quality of foodstuff.
(2) Biscuit and baked goods production
It has a significant inhibitory effect on starch retrogradation, which is particularly prominent when used in foodstuff. By utilizing the production of cookies and baked goods with beautiful color, soft and delicious texture, uniform organization, and good preservation, the storage period can be greatly extended. Starch retrogradation is one of the main reasons for the hardening of the taste and quality of biscuits and baked goods.
Its inhibition of starch retrogradation can maintain the softness and taste of food, extending its shelf life.
(3) Fast cooking noodle processing
Adding 0.1% -0.5% nipagin butyl ester to wheat flour used for instant noodles can also serve as a seasoning. The addition of butyl nipagin can improve the taste and quality of instant noodles, making them more delicious and tasty. At the same time, it can also extend the shelf life of instant noodles, making it convenient for consumers to store and use.
Synergistic effects with other ingredients in food
(1) Compound with other preservatives
Butyl nipagin can be used alone or in combination with other nipagin esters to achieve better anti-corrosion effects. In practical applications, in order to improve the anti-corrosion effect and reduce costs, nipagin butyl ester is often compounded with other preservatives such as sodium benzoate, potassium sorbate, etc. There is a synergistic effect between different preservatives, which can enhance the inhibitory effect on microorganisms and improve foodstuff safety.
(2) Compatibility with food additives
It can be compatible with various components present in cosmetics, and the test results show that its ability is not affected by surfactants, proteins, and other special additives in cosmetics. In foodstuff, it also has good compatibility and can be used together with other additives such as sweeteners, thickeners, coloring agents, etc., without affecting the quality and safety of the foodstuff.
Specific application methods in specific food systems
(1) Application in soy sauce
In soy sauce and other seasonings, due to its low solubility in water, it is usually prepared into ethanol solution, acetic acid solution, or sodium hydroxide solution for use. During the specific operation, 20% -25% butyl nipagin can be added to a 5% sodium hydroxide solution, and then slowly added to the soy sauce that has been heated to about 80 ℃. The dosage for preventing mold in soy sauce is 0.05-0.10g/L. Through this method, it can be evenly dispersed in soy sauce, exerting a good preservative effect.
(2) Application in Vinegar
Acetic aci or sodium hydroxide solution can be used to dissolve this substance in vinegar. The addition of vinegar can effectively inhibit the growth of microorganisms and prevent vinegar from spoiling. The specific amount added needs to be adjusted according to factors such as the type of vinegar, production process, and storage conditions.

(3) Application in refreshing beverages
In refreshing beverages, sodium hydroxide solution can be used to dissolve butyl nipagin, but butylparaben powder is usually used in combination with benzoic aci and dehydroacetic aci. The combination of different preservatives can improve the anti-corrosion effect and ensure the safety of refreshing beverages during storage and sales.
Core anti-corrosion applications in the food industry
(1) In the food industry, nipagin butyl ester is a food grade preservative approved for use in China's "Standard for the Use of Food Additives" GB 2760. Its core advantage is that it can achieve long-lasting preservation with extremely low addition amounts, without changing the flavor and taste of the food itself. In the field of meat products and cooked livestock and poultry products, nipagin butyl ester is often added in the form of sodium salt to sausages, ham, and braised meat products.
It can penetrate into the muscle fibers of meat products, inhibit the growth of microorganisms on the surface and deep layers, and effectively delay the problems of mold, acidification, and deterioration of meat products during refrigeration storage. Compared with traditional nitrate preservatives, its antibacterial spectrum is wider and it does not produce carcinogenic by-products such as nitrosamines. According to national standards, its maximum usage in meat products is 0.05g/kg, which fully meets the safety and preservation requirements of modern low-temperature meat products.
(2) In the fields of beverages, seasonings, and dairy products, the application scenarios of nipagin butyl ester are very extensive. In fermented seasonings such as soy sauce, vinegar, oyster sauce, etc., the high salt and high acidic environment of the system itself is prone to the growth of salt tolerant yeast and mold. Nipagin butyl ester can inhibit the growth of these salt tolerant microorganisms without changing the original flavor of the seasoning, solving the problems of white liquid surface, deterioration and sourness that occur during long-term storage of the seasoning, and greatly extending the shelf life of the product.

(3) In fruit juice drinks, plant protein drinks, and pasteurized milk products, adding a small amount of nipagin butyl ester can be combined with sterilization technology to achieve long-term preservation, avoiding microbial exceedance during transportation and storage of beverages. At the same time, its thermal stability is extremely strong, and it will not decompose or become inactive during the ultra-high temperature instant sterilization process of beverages, perfectly adapting to the continuous large-scale production needs of modern beverage industry.
(4) In the fields of noodle products, baked goods, and specialty foods, nipagin butyl ester also plays a unique role.
In baked goods with moderate moisture activity such as mooncakes and pastries, it can inhibit the growth and reproduction of mold, solve the pain point of pastry being prone to mold in high temperature and high humidity environments in summer, and extend the shelf life of products. In foods such as jam, candied fruit, jelly, etc., butyl nipagin is often used in combination with other nipagin esters to enhance the preservative effect through synergistic effects, achieving more comprehensive microbial inhibition at a lower total addition amount, which meets the development requirements of modern food industry for low-dose, high safety anti-corrosion agents.

Synthesis of Nipagin butyl ester:
It was prepared by esterification of p-hydroxybenzoic aci and n-butanol with concentrated sulfuric aci as catalyst;
Butyl p-hydroxybenzoate was synthesized with phosphoric aci as catalyst under microwave-assisted solvent-free conditions;
Rare earth solid superaci was used as catalyst and p-hydroxybenzoic aci and n-butanol as raw materials;
P-toluenesulfonic aci supported on granular activated carbon was used as catalyst and n-butanol was used as azeotropic water entraining agent to prepare p-hydroxybenzoic aci and n-butanol directly;
P-hydroxybenzoic aci and n-butanol are added into an azeotrope for esterification reaction to produce a product;
Butyl p-hydroxybenzoate with high yield was synthesized from n-butanol and p-hydroxybenzoic aci in the presence of sulfamic aci.

FAQ
What is the appearance of butylparaben?
It is a white solid that is soluble in organic solvents. It has proven to be a highly successful antimicrobial preservative in cosmetics. It is also used in medication suspensions, and as a flavoring additive in food.
Is butylparaben a paraben?
Parabens are used as preservatives in cosmetics, food, and medicines. Commonly used parabens include methylparaben (MP), propylparaben, and butylparaben.
What is butylparaben used for?
Common Uses of Butylparaben
Butylparaben is one of the most widely used preservatives in cosmetics, pharmaceuticals, and, to a lesser extent, food products. Due to its antimicrobial properties, it helps prevent the growth of bacteria, mold, and fungi, ensuring the safety and longevity of various consumer goods.
Is butylparaben safe for skin?
Butylparaben is safe for use when used within the concentration of 1% or less. Higher concentrations can cause skin irritation and allergic reactions, especially in users with sensitive skin.
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