Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of diazolidinyl urea powder cas 78491-02-8 in China. Welcome to wholesale bulk high quality diazolidinyl urea powder cas 78491-02-8 for sale here from our factory. Good service and reasonable price are available.
Diazolidinyl urea powder, white powder, with hygroscopicity, odorless or unique odor, molecular formula C8H14N4O7, CAS 78491-02-8. It is a new type of cosmetic preservative developed by Sutton Company in the 1980s. It has broad-spectrum antibacterial activity. Not only can it inhibit and kill Gram positive bacteria, bacteria, yeast, molds, and fungi, but it also has special effects on Gram negative bacteria such as Pseudomonas aeruginosa and Escherichia coli. There are no side effects within the dose range. Cationic, anionic, or non-ionic surfactants and proteins do not affect the bactericidal activity of diazoalkylurea. It is compatible with almost all cosmetic ingredients. Has broad-spectrum antibacterial activity, can inhibit Gram negative and positive bacteria, and has a certain inhibitory effect on yeast and mold. Diazoalkylurea was the most widely used new type of preservative in the world in the 1980s. It has broad-spectrum antibacterial activity and special effects against Gram negative bacteria. Its structure is similar to imidazolidinylurea, but it has better preventive effects on yeast, mold, and bacteria.
|
Chemical Formula |
C4H10N4O |
|
Exact Mass |
130 |
|
Molecular Weight |
130 |
|
m/z |
130 (100.0%), 131 (4.3%), 131 (1.5%) |
|
Elemental Analysis |
C, 76.45; H, 12.83; O, 10.72 |
|
|
|
Boiling point 421.04 ° C (rough estimate), Density 1.4734 (rough estimate), Refractive index 1.6590 (estimate), Storage condition 2-8 ° C, Solubility water (slightly), Acidity coefficient (PKA) 11.22 ± 0.46 (predicted), Form solid, Color white to off white, Merck 14,3000, Stable Incompatible with strong oxidizing agents. InChIKeySOROIESOUPGGFO-UHFFFAOYSA-N, arning, Hazard description h341-h317, Precautions p201-p202-p308+p313-p405-p501-p280, Dangerous goods sign Xi, Hazard category code 43, Safety instructions 36/37, WGK Germany 2, RTECS No. ys2717000.
Hydroxymethyl of Diazolidinyl urea powder is a sterilizing active group, which has sterilizing effect. It is one of the most frequently used preservatives in the cosmetics industry after Nipagin Esters. The application examples are as follows:
The raw materials and weight ratio in the formula are: 33 parts of mud yeast, 8 parts of vitamin E, 11 parts of pearl powder, 3 parts of malt starch, 7 parts of sodium pyrrolidone carboxylate, 1.6 parts of diazoalkyl urea, 0.05 parts of plant essential oil, 6 parts of polyvinyl alcohol, 2 parts of polyoxyethylene (20) sorbitan monolaurate, 2 parts of glycerol, and 100 parts of refined water. The dosage of the raw materials and the physical and chemical properties of the invention have a synergistic effect, so as to achieve the effect of removing free radicals and lightening spots. The pH value of the invention is close to the pH value of human skin and has no irritation to the skin; After use, it is obviously comfortable, soft, without greasy feeling, and has obvious moisturizing, whitening, repairing and nourishing effects.
2. prepare a new environmentally friendly printing ink
It is prepared from the following raw materials by weight: 26-32 parts of vinyl chloride acrylate copolymer resin, 3-4 parts of methyl methacrylate, 3-9 parts of acrylic resin, 4-7 parts of tri-n-butyl acetylcitrate, 10-13 parts of butyl octanol, 0.3-0.6 parts of 2-mercaptobenzoimidazole, 0.4-0.7 parts of diazoalkyl urea, 1-4 parts of attapulgite, 0.6-0.9 parts of ammonium persulfate, 0.5-0.8 parts of chitosan, 2-3 parts of palm oil, 3-5 parts of organic pigments, 4-6 parts of additives, and an appropriate amount of water. It has the advantages of low cost, diversified functions, antibacterial, high temperature resistance, high hardness, antibacterial, wear-resistant, chemical corrosion resistance, fast drying speed, good printing adaptability, etc. The preparation method is simple, convenient and practical.
It is composed of the following substances by weight percentage: 30% to 60% of environmental solvent, 2% to 4% of non-ionic surface activity, 3% to 8% of anionic surface activity, 0.5% to 2% of silicone defoamer, 0.5% to 2% of protective film, 0.05% to 0.1% of iodopropynyl n-butylcarbamate, 0.05% to 1% of diazoalkyl urea, 1,3-dihydroxymethyl-5,5-dimethylhydantoin, and 0.05% to 1% of RO water. The invention also protects the preparation method of the kitchen wipes compound liquid. The kitchen wipes prepared by the invention have the advantages of environmental protection, easy biodegradation, strong cleaning ability, no odor, less foam, no stimulation, no sticky feel, forming a protective layer on the hard surface, anti fouling and convenient for next cleaning.
4. prepare an environment-friendly corrosion and scale inhibition composition
Which comprises:10-18 parts by weight of modified polyepoxysuccinic acid, 10-20 parts by weight of acrylic acid copolymer, 5-12 parts by weight of tannin, 20-30 parts by weight of sodium silicate, 5-12 parts by weight of sodium d-gluconate, 10-20 parts by weight of polydiene dimethyl ammonium chloride, 8-10 parts by weight of zinc sulfate, 10-20 parts by weight of diazoalkylurea, and 50-80 parts by weight of purified water; The modified polyepoxysuccinic acid is obtained by copolymerization of epoxysuccinate with 2-acrylamide-2-methylpropanesulfonic acid and 3-propanol-2-enoyloxypropane-1-potassium sulfonate as monomers; The acrylic acid copolymer is obtained by copolymerizing acrylic acid with 2-acrylamide-2-methylpropanesulfonic acid and 2-acrylamide-phenylboric acid as monomers.
Cosmetics anti-corrosion
Diazoalkylurea has been widely used as a preservative in the cosmetics industry. Its broad-spectrum antibacterial activity enables it to effectively inhibit the growth and reproduction of various microorganisms such as Gram positive bacteria, Gram negative bacteria, yeast, mold, and fungi, thereby extending the shelf life of cosmetics and maintaining product stability and safety.
Application scope: Diazoalkylurea can be used in various cosmetics such as cream, lotion, shampoo, hair conditioner, liquid cosmetics, and eye cosmetics, including retention and wash off products.
Addition amount and usage method: The general addition amount is 0.1~0.3%, and it is better to add it to the cosmetic formula at a temperature below 50 ℃. It can be used in combination with nipagin esters and other preservatives to enhance the anti-corrosion effect.
Compatibility: Diazoalkylurea is compatible with almost all cosmetic ingredients and will not have adverse reactions with other ingredients in the formula, ensuring the stability and safety of cosmetics.
Food processing and feed industry anti-corrosion
In the food processing and feed industry, diazoalkylurea also plays an important role as a preservative. Its broad-spectrum antibacterial activity can effectively extend the shelf life of food and feed, prevent microbial contamination and spoilage.
Application scope: It can be used in various types of food and feed, such as pastries, meat products, dairy products, aquatic products, etc.
Safety: Within the prescribed usage range, diazoalkylurea has no adverse effects on the safety of food and feed. However, it should be noted that excessive use may have negative effects on human health, so strict control of usage is necessary.
Mechanism of action: Diazoalkylurea inhibits microbial growth and reproduction by disrupting their cell walls and membranes, interfering with their metabolic processes.
Diazolidinyl urea powder also has potential application value in the preparation of slow-release fertilizers. The active groups such as hydroxymethyl in its structure can combine with the nutrients in fertilizers to form stable compounds, thereby delaying the release rate of fertilizers and improving their utilization efficiency.
Principle of action: Diazoalkylurea combines with nutrients in fertilizers to form compounds with slow-release effects. These compounds can slowly decompose in soil, releasing nutrients for plants to absorb and utilize.
Advantages: The slow-release fertilizer prepared using diazoalkylurea has the advantages of long fertilizer efficiency, high utilization rate, and reduced nutrient loss. This helps to reduce agricultural production costs and improve crop yield and quality.
Preparation of polymer materials
In the preparation of polymer materials, diazoalkylurea can be used as a crosslinking agent or modifier to improve the properties of the polymer.
Crosslinking effect: The active groups in diazoalkylurea can react with the functional groups on the polymer molecular chain to form a cross-linked structure. This cross-linked structure helps to improve the strength, heat resistance, and chemical corrosion resistance of the polymer.
Modification effect: By introducing diazoalkylurea, the molecular structure and properties of the polymer can be changed, thereby endowing the polymer with new functional characteristics. For example, it can improve the processability of polymers, and improve the wear resistance and aging resistance of materials.
Other applications
In addition to the main applications mentioned above, diazoalkylureas also have potential application value in other fields. For example:
In the field of water treatment, diazoalkylurea can be used as a fungicide to kill harmful microorganisms in water and ensure the cleanliness and safety of water quality.
Ink preparation: In ink preparation, diazoalkylurea can be used as a dispersant or stabilizer, which helps improve the dispersibility and stability of ink and enhance printing quality.
Biomedical field: In recent years, studies have shown that diazoalkylureas also have potential application value in the biomedical field. For example, it can be used as a drug carrier or part of a gene delivery system to enhance drug targeting and bioavailability. However, research in this field is still in its infancy and requires further in-depth exploration and study.
Artificial preparation of Diazolidinyl urea powder: using 30% glyoxal as raw material, diazoalkylurea was prepared by oxidation reaction, cyclization reaction and hydroxymethylation reaction. Glyoxal was oxidized with nitric acid at 40 ℃ for 4H. Urea was added to the oxidation product and cyclized at 75 ℃ for 3h. The cyclized product allantoin and formaldehyde reacted at reflux temperature for 1H. The overall yield was 51%, and the nitrogen content of the product was 20.20% by elemental analysis. The purity of the product is 99% by fluorescence spectrum.
Step 1:
Preparation of allantoin. Add 0.25mol of glyoxal with a mass fraction of 30% to a four port flask equipped with an electric stirrer, condenser, constant pressure dropping funnel and thermometer, stir and raise the temperature to 40 ℃, drop 0.20mol of dilute nitric acid, complete the addition within 0.5h, after a total of 4H of heat preservation reaction, distill a certain amount of water and stand still, and recover the precipitated oxalic acid as a by-product. Add 0.8mol urea to the filtrate, add mixed acid catalysis under stirring, heat to 75 ℃, continue the reaction for 3h, then cool, filter, wash and dry to obtain allantoin, with a yield of 52% (calculated by glyoxal) and a melting point of 236 ~ 237 ℃.
Step 2: preparation of diazoalkyl urea.
Add 0.2mol allantoin and 0.8mol formaldehyde solution into a three port flask equipped with a stirrer and a reflux condenser, heat, stir and reflux (80 ℃) for 1h, then change the reflux device to a vacuum distillation device, evaporate the water, and dry to obtain 54.8g of diazoalkylurea, with a yield of 98%. The purity was 99% determined by fluorescence spectrum.
FAQ
Is diazolidinyl urea safe for skin?
Safety Profile
Diazolidinyl Urea has considerable risks involved in the form of skin sensitivities like irritation and redness, especially when used in concentrations higher than 0.5%. Due to its formaldehyde-releasing nature, it can exacerbate symptoms in those sensitive to formaldehyde.
What is diazolidinyl urea?
Diazolidinyl urea is an antimicrobial preservative that acts as a formaldehyde releaser in cosmetics and personal care products.
Is diazolidinyl urea the same as formaldehyde?
No. Urea is a moisturising and exfoliating ingredient. Diazolidinyl urea is a preservative that releases formaldehyde. They are chemically different and serve very different purposes in skincare.
How much diazolidinyl urea is safe?
The maximum authorized concentration for Diazolidinyl Urea is 0.5%. '") Cosmetic products formulated with Diazolidinyl Urea are typically applied to the eye area, skin, face, nails, and hair.
Hot Tags: diazolidinyl urea powder cas 78491-02-8, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, Sodium Polyacrylate Solution CAS 9003 04 7, 5 hydroxymethylfurfural synthesis, Sclareolide CAS 564 20 5, p Anisaldehyde liquid, Yeast Extract Powder CAS 8013 01 2, s allyl l cysteine