Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of isopropyl myristate liquid cas 110-27-0 in China. Welcome to wholesale bulk high quality isopropyl myristate liquid cas 110-27-0 for sale here from our factory. Good service and reasonable price are available.
Isopropyl Myristate Liquid, colorless transparent oily liquid. Insoluble in water; It can be miscible with alcohol, ether, methylene chloride, grease, and other organic solvents. Widely used in cosmetics, it can moisturize and moisturize the skin. The skin has good absorption of this product. It can effectively contact hair follicles in the cortex, penetrate deep into the cortex, and bring the active components in cosmetics into full play. As a cosmetic solvent, skin moisturizer, and penetrant. It can be used in sol products, bath oil, hair conditioner, skin cream, sunscreen, shaving cream, and other cosmetics. General recommended dosage: 2 ~ 10% This product is one of the essential ingredients of high-grade cosmetics. It has excellent penetration, moisturizing, and softening effects on the skin. It is used as an emulsifier and wetting agent for cosmetics.


| Chemical Formula | C17H34O2 |
| Exact Mass | 270 |
| Molecular Weight | 270 |
| m/z | 270 (100.0%), 271 (18.4%), 272 (1.6%) |
| Elemental Analysis | C, 75.50; H, 12.67; O, 11.83 |


We are the supplier of isopropyl myristate liquid.
Remark: BLOOM TECH(Since 2008), ACHIEVE CHEM-TECH is our subsidiary.

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Melting point ~ 3 ° C (lit.), Boiling point 193 ° C / 20 mmHg (lit.), Density 0.85 g / ml at 25 ° C (lit.), Vapor pressure < 1 HPA (20 ° C), FEMA 3556 | ISOPROPYL MYRISTATE, Refractive index N20 / D 1.434 (lit.), Flash point > 230 ° f, Storage condition 2-8 ° C, Solubility < 0.05mg/l Form liquid Color clear Specific gravity 0.855 (20 / 4 ℃) Miscible with alcohol Immiscible with water and glycerol. JECFA Number311 Merck 14,5215 BRN 1781127 Stable Combustible. Incompatible with strong oxidizing agents. InChIKeyAXISYYRBXTVTFY-UHFFFAOYSA-N


Isopropyl myristate is a nonfat emollient that is easily absorbed by the skin. It is one of the components of a semi-solid matrix and can also be used as a solvent for many substances in local drug delivery preparations. It is applied to various local practices and cosmetics, including bath oil, cosmetics, hair and armor products, face cream, lotion, lipstick, shaving cream, emollient, deodorant, ear suspension, and vaginal cream.
For example, isopropyl myristate is a self-emulsifying ingredient in a cold cream prescription, which can be used as the matrix of many drugs and skin drugs; In cosmetics, it is also used in the stable mixture of water and glycerol. Isopropyl myristate can be used as a penetration enhancer in transdermal absorption preparations and combined with therapeutic ultrasound and iontophoresis. Isopropyl myristate can be used as the main component of the oil phase in water oil gel prolonged-release emulsion.
When isopropyl myristate contacts rubber, rubber swells partially dissolve, and viscosity decreases; These materials will pour when they reach nylon. Isopropyl myristate and solid paraffin are incompatible and form a granular mixture and should not be compatible with strong oxidants. Synthetic isopropyl myristate is prepared by esterifying isopropyl myristate and isopropanol or reaction of myristoyl chloride and 2-propanol in the presence of a suitable dehydrochlorination reagent. Commercially available high-purity isopropyl myristate is prepared by enzymatic esterification at low temperatures.

As an important additive ingredient in the cosmetic industry, isopropyl myristate has a variety of excellent properties and application values:
Emollient:
Isopropyl myristate is a polar emollient that penetrates the skin to provide nourishment and moisturization. This helps to improve dryness and roughness of the skin, making it softer and smoother.
Dispersant:
In cosmetics, Isopropyl Myristate is also used as a dispersant to help other ingredients disperse evenly in the cosmetic matrix, improving the stability and uniformity of the product.
Fragrance fixing agent:
In addition, isopropyl myristate can be used as a perfume fixing agent, which can prolong the persistence of the fragrance and make the perfume more long-lasting and charming.
In the development and production of cosmetics, the amount of isopropyl myristate added and the way it is used may be adjusted depending on the type of product and the needs of the formulation. For example, in cosmetics such as lipsticks, hair creams, lip balms, cleansing creams, and perfumed powders, isopropyl myristate may be used as an important additive ingredient for its emollient, dispersing, and scent fixing effects.
Safety and regulations
The use of isopropyl myristate in cosmetics and drugs needs to comply with relevant safety and regulatory requirements. For example, in cosmetics, its use and purity need to comply with relevant regulations and standards to ensure the safety and effectiveness of the product. Meanwhile, in the process of drug development and production, strict safety and efficacy assessment is also required to ensure the quality and safety of drugs.

Isopropyl myristate, a colorless, transparent, low viscosity oily liquid saturated fatty acid ester at room temperature and pressure, is obtained by catalytic esterification, neutralization and distillation of myristic acid and isopropanol. It is a highly versatile liquid ester additive raw material in the fine chemical industry chain. Insoluble in water and glycerol, infinitely miscible with alcohols, ethers, ketones, halogenated hydrocarbons, animal and vegetable oils, mineral oils; Excellent chemical stability, not easily oxidized and rancid at room temperature, high tolerance in mild acidic and alkaline environments, only strong high temperature and concentrated acidic and alkaline environments will hydrolyze to produce myristic acid and isopropanol.
Organic synthesis chemical reaction medium and extraction solvent
IPM liquid ester is a safe reaction medium that can replace toluene, xylene, high boiling mineral oil, and paraffin oil in a green way. It is widely used in fine organic synthesis processes such as esterification, amidation, reduction, alkylation, rearrangement, chiral separation, and high-temperature condensation. It belongs to a low toxicity green solvent system without aromatic hydrocarbons.
The synthesis of heterocyclic drug intermediates, essence heterocyclic compounds and amide surfactants often requires 120 – 200 ℃ constant temperature reflux; Toluene and xylene have low boiling points and cannot adapt to high temperatures, while mineral oil is prone to cracking and producing olefin impurities at high temperatures;

IPM has a boiling point of 319 ℃, strong thermal stability, and no volatilization loss or carbonization coking throughout the process. Typical process: Pyridine and oxazole based edible meat flavorings are synthesized by cyclization. IPM is used as the heat transfer solvent in the reaction vessel. After the reaction is completed, the products are separated by vacuum distillation (vacuum -0.09 MPa, 210 ℃). IPM is recycled and reused, reducing the discharge of organic waste liquid by 65%.
Solvent for ester exchange and synthesis of fatty acid derivatives
When preparing polyol fatty acid esters, sorbitol esters, sucrose esters, and glycerol monoesters as food/emulsifying aids, IPM can dissolve solid polyols and long-chain fatty acids, increase the contact area between the two phases, and increase the DCC/DMAP catalytic esterification conversion rate by 12% -18%; After the reaction, the water is washed and layered, and the IPM organic phase is quickly separated to avoid the high-pressure explosion risk caused by low-carbon alcohol solvents such as methanol and ethanol.
Reduction reaction mild medium (metal hydride, catalytic hydrogenation)
Diisobutylaluminum hydride (DIBAL-H) and sodium borohydride are used for the reduction of fatty alcohols, nitriles, aldehydes, and ketones. IPM does not react with strong reducing agents and has no explosive exothermic side reactions; For example, the synthesis process of tetradecanitrile: Isopropyl myristate in ammonia, iodine, and DIBAL-H systems using IPM as the solvent, with a reaction yield of 90% after 3 hours and no solvent explosion hazard, far superior to ether based high-risk solvent systems.
Extraction and separation solvents for natural products and plant active ingredients
The chemical extraction workshop is used for liquid-liquid extraction of lipid soluble plant flavonoids, sterols, terpenes, and polyphenols; IPM has strong solubility for lipophilic active substances, and extraction at room temperature does not require high temperature to damage the effective structure; The extraction solution can be directly used for subsequent formulation compounding without completely removing IPM (IPM itself can be used as a formulation aid); Compared to n-hexane extraction, IPM has a higher flash point, extremely low volatility, an 80% reduction in workshop VOC emissions, and a significant increase in explosion-proof safety level.

Chiral Separation and Crystallization Recrystallization Solvent Additives
Separation of enantiomers of chiral pharmaceutical intermediates and fragrances, formation of gradient polar mixed solvents by compounding IPM with ethanol and water, regulation of crystal precipitation rate, and improvement of chiral purity; For lipid soluble and difficult to crystallize active pharmaceutical ingredients, IPM can reduce crystallization viscosity, minimize encapsulated impurities, and increase product purity to over 99.5% after recrystallization.
Industrial universal solvent, dispersant, and system stabilizer
IPM liquid raw material is a multi-functional dissolution and dispersion carrier in the chemical compound formula, covering the dissolution needs of all kinds of oils, waxes, resins, toners, essence, fat soluble additives, and is suitable for upgrading aromatic free environmental protection formula.
In industrial hot melt adhesive, demolding wax, and polishing wax systems, high molecular weight polyethylene wax and microcrystalline paraffin wax solidify at room temperature and are prone to agglomeration and agglomeration after high-temperature melting; Adding 5% -15% IPM liquid raw materials can completely dissolve wax, reduce melt viscosity, and improve the uniformity of wax spreading on resin and metal surfaces; IPM in the polishing wax formula can enhance glossiness without white mist or oil residue.
Resin and oligomer dilution viscosity reducing solvents
Epoxy resin, acrylic oligomers, polyurethane prepolymers, and high viscosity alkyd resin systems, IPM as a high boiling point active dilution agent, will not damage the resin curing cross-linking structure; Adding 3% -10% IPM can reduce the construction viscosity of the system, improve the leveling performance of spraying and brushing, and slowly and slightly penetrate and migrate the IPM to the surface after curing to form a flexible protective film, thereby enhancing the bending resistance of the paint film; Different from acetone and ethyl acetate fast drying solvents, IPM slow drying can extend the open construction time.
Inorganic/organic color powders, carbon nanotubes, pigment dispersion carriers
Inkjet ink, industrial color paste, plastic masterbatch powder dispersion process: IPM wets the surface of carbon black, organic pigments, iron oxide, and carbon nanotube powder to break particle agglomeration. After grinding with dispersant, the color paste is stored for 6 months without settling or layering; In the formula of conductive carbon nanotube ink, IPM stabilizes the dispersion of carbon nanotubes and maintains a stable electrical resistivity within the range of 10 Ω· cm, making it suitable for the chemical production of flexible electronic printing pastes.

Special chemical solvents for essence, spice and fixative
The core liquid carrier in the fine spice chemical industry can dissolve terpenes, esters, aldehydes and ketones, musk, and plant essential oils; IPM is extremely low in volatility and has a long-term fragrance fixing effect. Adding 2% – 30% IPM to the essence formula can slow down the loss of highly volatile fragrance components and extend the duration of fragrance retention; Perfume, aromatherapy, industrial air freshener, essence base mainstream solvent, free of methanol, benzene toxic impurities, food grade IPM can be directly used for the preparation of edible essence.
System pH Buffer and Anti Stratification Stabilizer
In the water oil two-phase emulsification chemical formula (cutting fluid, pesticide emulsified oil, cleaning lotion), IPM adjusts the polarity of oil phase, balances the HLB range of emulsifier, and improves the stability of lotion cold and hot cycle (-10 ℃~60 ℃, no layering or demulsification repeatedly); Inhibit oil oxidation and rancidity, and extend the shelf life of the formula by more than twice.
Core lubricant additive for metal processing fluid chemical system (green cutting/stamping/rust proof fluid raw material)
Metal fine processing chemical industry is the second largest application scenario of IPM industrial grade. Relying on the advantages of biodegradability, low friction, sulfur and phosphorus free, and low corrosion, it comprehensively replaces toxic lubricating components such as mineral oil, sulfurized lard, and chlorinated paraffin, and is suitable for the production of precision machining fluid formulas for aluminum, magnesium, stainless steel, copper, and alloys.
Precision cutting fluid and honing fluid lubricating base
Aluminum alloy, magnesium alloy, aerospace titanium alloy, stainless steel CNC cutting chemical formula: Industrial grade IPM addition amount of 0.5% -3%, adsorption metal tool and workpiece friction interface form ultra-thin lubricating film, friction coefficient is reduced to 0.05, tool service life is extended by 30%; IPM does not contain sulfur or chlorine, and will not corrode the active metal surfaces of aluminum and magnesium. There are no blackening or pitting defects on the workpiece; IPM in water-based semi synthetic cutting fluid, as an oil phase lubricating component, is combined with anionic emulsifier to form a stable micro lotion. The waste liquid is naturally degraded by more than 70% in 28 days, which meets the EU Ecolabel environmental protection emission standard.
Lubricating chemical oils for stamping, stretching, and cold rolling forming
Formula for deep stamping forming oil of thin plate stainless steel, copper foil, and aluminum shell: IPM compound extreme pressure ester, rust and corrosion inhibitor, does not tear the surface of the workpiece under high elongation conditions, and the oil film on the surface of the workpiece is easily removed by alkali washing after forming, without stubborn mineral oil spots; Compared with the chlorinated paraffin system, IPM has no chlorine element, and subsequent electroplating and spraying pre-treatment do not require dechlorination processes, simplifying the chemical cleaning process.


Metal rust prevention, sealing and protection of oil and chemical raw materials
Short term workpiece sealing anti rust oil and inter process anti rust thin layer oil: IPM combined with organic carboxylic acid corrosion inhibitor, the thin oil film evenly spreads on the surface of steel plates, copper pipes, and aluminum profiles, isolating water vapor and oxygen; The oil film is easy to wipe and clean, and there are no carbon deposits or coating peeling issues during subsequent welding and spraying; Low viscosity IPM substrate is preferred as the rust proof oil for precision instruments and micro parts of bearings, which will not penetrate into small bearing gaps and cause jamming.
Modified additives for electrical discharge and wire cutting working fluids
Adding a small amount of IPM (0.2% -1%) to the working fluid for slow wire cutting improves the lubricity of the medium between the electrode wire and the workpiece, reduces discharge spark oxidation erosion, reduces the machining roughness Ra value of the workpiece, and improves cutting accuracy; IPM has moderate insulation and does not interfere with the stable operation of pulse discharge.

Frequently Asked Questions
Is Isopropyl Myristate a liquid?
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Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.It is a colorless and odorless liquid that is a common ingredient in pharmaceutical and cosmetic preparations.
What is the difference between IPP and IPM?
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What's the difference between Isopropyl Myristate and Isopropyl Palmitate?Both are lightweight esters that reduce greasiness in formulations.IPM acts primarily as a penetration enhancer, while IPP provides conditioning and softness.
Is Isopropyl Myristate safe to use on skin?
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Isopropyl myristate is safe for most skin types and widely used in cosmetics as an emollient and penetration enhancer.While non-toxic and non-irritating, it has a high comedogenic rating, meaning it can clog pores and trigger breakouts for acne-prone or oily skin.
Is isopropyl myristate oil soluble?
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At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil;practically insoluble in glycerol, propylene glycol.
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