5a Hydroxy Laxogenin Powder
video
5a Hydroxy Laxogenin Powder

5a Hydroxy Laxogenin Powder

1.We supply
(1)Tablets
(2)Cream
(3)API(Pure powder)
(4)Pill press machine
https://www.achievechem.com/pill-press
2.Customization:
We will negotiate individually, OEM/ODM, No brand, for secience researching only.
Internal Code: BM-1-078
5a-hydroxy laxogenin CAS 56786-63-1
Analysis: HPLC, LC-MS, HNMR
Technology support: R&D Dept.-1

Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 5a hydroxy laxogenin powder in China. Welcome to wholesale bulk high quality 5a hydroxy laxogenin powder for sale here from our factory. Good service and reasonable price are available.

 

5a Hydroxy Laxogenin powder is a naturally occurring spirosterane compound in plants. Its chemical name is (3β,5α,25R)-3, 5-dihydroxyspirosterane-6-one, with the molecular formula C₂₇H₄₂O₅ and a molecular weight of 446.62 g/mol. From a chemical classification perspective, 5α-Hydroxy Laxogenin belongs to Brassinosteroids. These compounds are widely present in plants and are involved in regulating processes such as growth, development, and stress response.

 

5a Hydroxy Laxogenin Powder | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin Powder | Shaanxi BLOOM Tech Co., Ltd

product-339-75

Chemical Nature and Structural Characteristics
 

5a Hydroxy Laxogenin powder is a naturally occurring snail sterane compound in plants, with the molecular formula C₂₇H₄₂O₅ and a molecular weight of 446.62 g/mol.

 

Its core structure is composed of four cyclic systems (A, B, C, and D rings), among which the C3 and C5 sites respectively have hydroxyl groups (-OH), and the C6 site is a ketone group (=O), forming a unique 3β,5α -dihydroxyspirane-6-ketone skeleton.

 

This structure endows it with high chemical inertness. Under normal storage conditions (25℃, relative humidity 60%), the annual degradation rate is less than 0.5%, and it is stable to light and heat (melting point 247-250℃, DSC analysis shows that the thermal decomposition peak is above 280℃).

Manufacturing Information-

Source and Extraction Process
 

Natural source

Plants of the genus Smilax: such as the underground stems of Smilax china, which contain approximately 0.06% of 5α-Hydroxy Laxogenin, are the main extraction raw materials.

Allium plants: They can also be isolated from the bulbs of Onions (Allium cepa), but in lower amounts.

 

Extraction method

Solvent extraction: Using ethanol or methanol as the solvent, crude products are obtained through impregnation, reflux or ultrasonic-assisted extraction, followed by concentration and crystallization.

Chromatographic purification: Further separation is carried out using silica gel column chromatography or high performance liquid chromatography (HPLC) to obtain high-purity (≥98%) products.

Biosynthesis: By using yeast or plant cell fermentation technology and metabolic engineering methods to increase yield, it is still at the laboratory stage at present.

Physiological Functions and Mechanisms

5a Hydroxy Laxogenin price | Shaanxi BLOOM Tech Co., Ltd

01

Anabolic effect

Protein synthesis promotion: Studies have shown that it can significantly increase the rate of protein synthesis (by more than 200%), and the mechanism may be related to the activation of the mTOR signaling pathway.

Enhanced nitrogen retention: By reducing nitrogen excretion in the urea cycle, it improves the nitrogen balance in the body and provides raw materials for muscle growth.

Anti-catabolic effect: Inhibits the activity of cortisol (a catabolic hormone), reduces muscle protein breakdown, and accelerates recovery.

02

Improvement in athletic performance

Strength growth: User feedback indicates that strength significantly increases after continuous use for 3 to 5 days, which may be related to neuromuscular adaptation and thickening of muscle fibers.

Muscle mass increase: Lean body mass can be observed within 3 to 4 weeks, with an effect similar to that of low-dose anabolic steroids, but without hormonal side effects.

5a Hydroxy Laxogenin buy | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin cost | Shaanxi BLOOM Tech Co., Ltd

03

Metabolic regulation

Fat breakdown: By inhibiting phosphodiesterase (PDE), increasing intracellular cyclic adenosine monophosphate (cAMP) levels, and activating hormone-sensitive lipase (HSL), fat breakdown is promoted.

Improvement of insulin sensitivity: Animal experiments have shown that it can enhance insulin signal transduction, reduce blood sugar fluctuations, and potentially be beneficial to diabetic patients.

04

Safety advantage

Non-hormonal: It does not interfere with the hypothalamic-pituitary-gonadal axis (HPTA) and does not cause testosterone suppression or estrogen-related side effects (such as breast development in men).

No risk of doping: Its metabolites are not tested for regular drug tests, and thus are used by some athletes as compliant supplements.

5a Hydroxy Laxogenin online | Shaanxi BLOOM Tech Co., Ltd

Application Scenarios

5a Hydroxy Laxogenin for sale | Shaanxi BLOOM Tech Co., Ltd

Functional Food and Health Management

With the popularization of health management concepts, 5α-Hydroxy Laxogenin Powder has been gradually applied in the functional food industry by virtue of its mild physiological activity. It is mainly used in scenarios such as middle-aged and elderly care, high-pressure workplace population conditioning and male health management, providing natural health support.

Prevention of age-related muscle loss

As people age, endogenous hormone levels gradually decline in the middle-aged and elderly, prone to sarcopenia symptoms including muscle atrophy and strength decline, which seriously impair quality of life. 5α-Hydroxy Laxogenin Powder can mildly promote protein synthesis, reduce muscle breakdown, and delay the onset and progression of sarcopenia. It helps the middle-aged and elderly maintain muscle mass and physical strength, and improve mobility. At present, this ingredient has been added into middle-aged and elderly protein powder, nutritional milkshakes and dietary supplements as a daily nutritional component for muscle health support. 

5a Hydroxy Laxogenin purchase | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin uses | Shaanxi BLOOM Tech Co., Ltd

Stress management and metabolic regulation

As a natural adaptogen, this ingredient modulates cortisol levels and thyroid function in the human body, alleviating muscle loss, metabolic slowdown, fatigue and lassitude caused by long-term high stress, and helping the body adapt to stressful conditions. Meanwhile, relevant studies have shown that it can assist in regulating blood glucose levels and lowering low-density lipoprotein (bad cholesterol), exerting a certain protective effect on cardiovascular health. It is suitable for daily health management of high-pressure workplace groups and populations at risk of metabolic syndrome, helping improve physical condition and boost energy.

Male health support

5α-Hydroxy Laxogenin Powder can mildly stimulate testosterone synthesis, improve male physical vitality, and relieve symptoms such as fatigue, weakness, muscle loss and low mood during male menopause. It has no side effects associated with hormone replacement therapy and features high safety. Currently, it is widely incorporated into male vitality supplements and multivitamins as a natural hormone-regulating ingredient, delivering mild and safe support for male health.

5a Hydroxy Laxogenin Male health support | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin Animal Husbandry And Animal Nutrition | Shaanxi BLOOM Tech Co., Ltd

Animal Husbandry and Animal Nutrition

In the livestock breeding industry, 5α-Hydroxy Laxogenin Powder has become an ideal alternative to traditional growth hormones due to its natural origin, zero residue and growth-promoting properties.It is widely used in the breeding of live pigs, beef cattle, broilers and other livestock and poultry, facilitating the efficient and green development of the breeding industry.

Livestock and poultry growth promotion

A large number of animal experiments have confirmed that this ingredient can enhance the protein synthesis efficiency of livestock and poultry, promote muscle growth, increase lean meat rate, accelerate weight gain and shorten the breeding cycle. Compared with traditional growth hormones, it carries no risk of hormone residue, does not affect the quality of livestock and poultry products, and poses no harm to human health, complying with the requirements of green breeding and food safety. Adding it to livestock and poultry feed can significantly improve breeding efficiency and reduce production costs, especially suitable for large-scale livestock and poultry breeding enterprises.

5a Hydroxy Laxogenin Livestock and poultry growth promotion | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin Development support for young animals | Shaanxi BLOOM Tech Co., Ltd

Development support for young animals

5α-Hydroxy Laxogenin Powder significantly promotes the growth of the liver, heart, kidneys and muscle tissues of young animals, enhances their immunity, reduces the incidence of diarrhea, respiratory infections and other diseases, and improves the survival rate and health level of young animals. At present, this ingredient is applied in feed and nutritional supplements for young animals, safeguarding their healthy development and supporting the sustainable development of the breeding industry.

Plant Growth Regulation and Agricultural Applications

As a brassinosteroid analog, 5α-Hydroxy Laxogenin Powder exhibits significant plant growth regulation effects at low concentrations (0.1-1 μM). It can boost plant growth and enhance stress resistance, and is widely used in agricultural production and horticulture to support crop yield increase and stress-resistant cultivation.

Crop yield improvement

Combined application of this ingredient with fertilizers can markedly increase the yield and fresh weight of vegetables such as lettuce and chicory, while optimizing crop quality and nutritional value.

5a Hydroxy Laxogenin Crop yield improvement | Shaanxi BLOOM Tech Co., Ltd

5a Hydroxy Laxogenin Stress-resistant cultivation | Shaanxi BLOOM Tech Co., Ltd

In addition, it can inhibit plant growth retardation induced by salt stress, holding important application value in saline-alkali land cultivation. It helps crops adapt to saline-alkali environments and improves survival rate and yield.

Stress-resistant cultivation

This ingredient enhances plant tolerance to adverse environments such as salinity, drought and low temperature, reduces ethylene release in plants, delays leaf senescence, and improves crop survival rate under extreme conditions.

For agricultural regions frequently affected by drought and low temperature, the addition of this ingredient can effectively mitigate the impact of natural disasters on crop yield and stabilize agricultural production.

Horticultural application

5α-Hydroxy Laxogenin Powder can promote the growth of flowers and seedlings, enhance the ornamental value of flowers and the survival rate of seedlings, and is applicable to high-end horticulture and seedling cultivation. When applied to flower planting, it can prolong the flowering period and improve flower fullness; when used in seedling cultivation, it stimulates root growth, strengthens the stress resistance of seedlings and optimizes seedling quality.

5a Hydroxy Laxogenin Horticultural application | Shaanxi BLOOM Tech Co., Ltd

Quality standard
 

Purity: The proportion of the main peak area detected by HPLC is ≥98%, and impurities (such as related steroids) are ≤1%.

 

Heavy metals: Lead (Pb) ≤1 ppm, arsenic (As) ≤0.5 ppm, mercury (Hg) ≤0.1 ppm.

 

Microorganisms: Total colony count ≤1000 CFU/g. Escherichia coli and Salmonella shall not be detected.

Future Development Trends

 

 

With the advancement of synthetic biology technology, the biosynthetic pathway of 5a Hydroxy Laxogenin powder is expected to be optimized, reducing production costs and increasing yields. Meanwhile, its potential in areas such as metabolic diseases and tumor treatment is being gradually tapped, and it may be extended to more medical application scenarios in the future.

product-349-72

Fundamentals of Chemical Stability
 

The molecular structure is related to stability

The molecular formula of 5α-Hydroxy Laxogenin is C₂₇H₄₂O₅. Its sterane skeleton (composed of A, B, C, and D tetracycles) forms an intramolecular hydrogen bond network with the hydroxyl groups (-OH) at C3 and C5 sites. This structure endows it with high chemical inertness. Experimental data show that under conditions of 25℃ and a relative humidity of 60%, the degradation rate of its pure powder (≥98% purity) is less than 0.5% per year, indicating its excellent basic chemical stability.

Thermal stability

The melting point is determined to be 247-250℃, which is much higher than the conventional storage temperature, indicating that it will not melt or decompose when heated below 200℃. DSC (Differential Scanning calorimetry) analysis revealed that its thermal decomposition peak occurred above 280℃, further verifying its stability in high-temperature environments.

 

Optical stability

The ultraviolet (UV) irradiation experiment shows that after continuous irradiation for 72 hours at a wavelength of 254nm and an intensity of 10W/m², its content decreases by only 1.2%, and no new impurities are generated. This is attributed to the absence of its conjugated double bond system, which reduces the free radical reactions triggered by light absorption.

FAQ
 
 

What is 5a hydroxy Laxogenin used for?

+

-

Laxogenin and 5-alpha-hydroxy laxogenin are taken by mouth to build muscle and increase strength. Laxogenin is a natural chemical found in plants. It helps the plant to grow. Some people think that it might promote muscle growth in humans.

 

Hot Tags: 5a hydroxy laxogenin powder, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, eriodictyol powder, filgotinib, Medetomidine hydrochloride, Articaine Hcl powder, tetracaine hcl, 3 DiMethylaMino 1 4 Methoxyphenyl prop 2 en 1 one CAS 18096 70 3

Send Inquiry