Ivermectin powder CAS 70288-86-7,is a novel broad-spectrum and highly effective antiparasitic product. The appearance is white or light yellow crystalline powder, odorless. It is soluble in methanol, ethanol, acetone, or ethyl acetate, but almost insoluble in water. Mainly used for treating human diseases and broad-spectrum anti parasitic therapy. It has significant killing and inhibitory effects on various parasites such as nematodes, silkworms, roundworms, whipworms, and pinworms. It should be sealed and stored away from light to ensure its quality and effectiveness.
The different adjuvants contained in the commercial formulation of Stromectol can affect the effectiveness of the drug. For example, when sheep take a formulation containing Tween-80 as an adjuvant orally, Ivermectin is still safe at a dosage of 4000 μ g/kg. However, if propylene glycol is used as an adjuvant, it can cause ataxia and hemoglobinuria in sheep for 3 days. Ivermectin injection containing Tween-80 as an adjuvant in the United States is a specialized commercial preparation for equine animals, but it cannot be used for dogs, otherwise it is extremely unsafe.
At the same time, our company not only provides ivermectin stromectol tablets, but also cream, paste and powders. If needed, please feel free to contact us at any time.
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Additional information of chemical compound:
| Product Name | Ivermectin stromectol powder | Ivermectin stromectol tablet |
| Product Type | Powder | Tablets |
| Product Purity | HPLC≥99.0% | ≥99% |
| Product Specifications | 100g/1kg/etc. | 360mg/Tablet |
| Product Package | PE/Al foil bag/ paper box for Pure powder |
100 tablets/Bottle 80 bottles/Box |
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Ivermectin Stromectol COA
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Certificate of Analysis |
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Compound name |
Ivermectin | |
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CAS No. |
70288-86-7 | |
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Grade |
Veterinary grade |
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Quantity |
5kg | |
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Packaging standard |
5kg/Bag |
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| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
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Lot No. |
20250109001 |
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MFG |
Jan 9th 2025 |
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EXP |
Jan 8th 2028 |
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Structure |
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| TEST STANDARD | GB/T24768-2009 Industry. Stnndard | |
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Item |
Enterprise standard |
Analysis result |
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Appearance |
White or almost white powder |
Conformed |
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Water content |
≤5.0% |
0.31% |
| Loss on drying |
≤1.0% |
0.15% |
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Heavy Metals |
Pb≤0.5ppm |
N.D. |
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As≤0.5ppm |
N.D. | |
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Hg≤0.5ppm |
N.D. | |
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Cd≤0.5ppm |
N.D. | |
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Purity (HPLC) |
≥99.0% |
99.4% |
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Single impurity |
<0.8% |
0.48% |
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Residue on ignition |
<0.20% |
0.064% |
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Total microbial count |
≤750cfu/g |
80 |
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E. Coli |
≤2MPN/g |
N.D. |
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Salmonella |
N.D. | N.D. |
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Ethanol (by GC) |
≤5000ppm |
400ppm |
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Storage |
Store in a sealed, dark and dry place at-20 degrees |
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Additional information of chemical compound:
| Chemical Formula | C48H74O14 |
| King-Single | 874.51 |
| Exact Mass | 874.11 |
| m/z | 874.51(100.0%),875.51(51.9%),876.51 (13.2%), 876.51 (2.9%), 877.52 (1.5%), 877.52 (1.4%) |
| Elemental Analysis | C, 65.88; H, 8.52; O, 25.60 |
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Animal use field
In animal husbandry, Ivermectin powder is widely used to control and treat parasitic infections in animals. Specifically, it is commonly used for:
- Parasitic control in the gastrointestinal tract of ruminant animals such as cows, sheep, horses, etc.
- Prevention and treatment of intestinal nematodes, ear mites, scabies mites, heartworms, and microfilaments in dogs.
- Treatment of gastrointestinal and pulmonary nematodes in pigs.
- Expulsion of gastrointestinal nematodes and ectoparasites in poultry.
Human use field
This substance is not only used in animals, but also has significant therapeutic effects on human parasitic infections. Specifically, it can be used for treating:
- Onchocerciasis (river blindness): It is one of the main drugs for treating Onchocerciasis, which can effectively alleviate the condition and prevent disease progression.
- Lymphatic filariasis: Ivermectin also has significant therapeutic effects on lymphatic filariasis.
- Nematode like disease: This substance can be used to treat nematode like disease and alleviate symptoms in patients.
- Skin diseases such as rosacea (rosacea) and blepharitis caused by Demodex folliculorum can be effectively treated with topical creams (such as Soolantra).
Mechanism of action
The mechanism of action of this substance is mainly achieved by interfering with the parasitic nervous system. It specifically binds to and activates glutamate gated chloride ion channels in parasitic nerve and muscle cells, leading to neuronal membrane hyperpolarization and causing parasite paralysis and death. Due to significant differences in chloride ion channels between mammals and parasites, it is relatively safe for vertebrates and does not have a significant impact on them.
precautions
- The usage and dosage of this product vary depending on the specific condition and should be determined by a doctor based on the patient's weight and condition.
- When using it, attention should be paid to its possible side effects, such as fever, dizziness, general weakness, headache, itching, rash, etc. If serious side effects occur, seek medical attention immediately.
- It should be stored in a sealed, room temperature, dark, and dry environment to ensure its stability and effectiveness.
Ivermectin powder as a broad-spectrum antiparasitic drug, has broad application prospects in the fields of medicine and veterinary medicine. The following is a detailed analysis of its development prospects:
1.Market demand continues to grow
Global demand for parasitic disease prevention and control:
This product has significant therapeutic effects in treating various parasitic diseases, such as lymphatic filariasis, panococcal filariasis, schistosomiasis, etc. These diseases are particularly common in developing countries and regions, so their demand is huge in these areas.
With the continuous improvement of global health conditions and the improvement of medical standards, people's awareness of parasitic disease prevention and control is gradually increasing, which will further promote the market demand for this substance.
Widely used in the field of veterinary medicine:
This substance has also shown extensive application value in the veterinary field, mainly used for the prevention and treatment of parasitic diseases such as heartworm and mite diseases in animals.
With the rapid development of the pet industry and people's increasing concern for pet health, the market demand for this substance in the pet medical field is also continuing to grow.
2.Technological progress drives application expansion
In depth study of the mechanism of action
With the in-depth study of the mechanism of action of this product, people have gained a deeper understanding of its efficacy in anti parasitic treatment. This will help promote the application and expansion of the substance in more fields.
Development of new technologies and dosage forms
Researchers are constantly exploring the development of new technologies and dosage forms to improve the efficacy and reduce side effects of this product. For example, by changing the way drugs are administered and improving their bioavailability, their therapeutic efficacy can be further enhanced.
3.Exploring potential application areas
Antiviral and anti-tumor research
In addition to its anti parasitic effects, researchers are also exploring the potential applications of this substance in antiviral and anti-tumor fields. These studies are expected to provide new directions for its application expansion.
Applications in other medical fields
This substance may also play important roles in other medical fields, such as treating certain skin diseases, neurological disorders, etc. The exploration of these potential application areas will further drive its market development.
4.Challenges and opportunities faced
Drug resistance issue:
With the increasing resistance of parasites to drugs, this product is also facing resistance issues. This requires researchers to continuously explore new drug targets and treatment strategies to address the challenges posed by drug resistance.
Policy support and market access:
In some countries and regions, the government has provided certain policy support for the prevention and control of parasitic diseases.
These policies will promote market access and widespread use of antiparasitic drugs that have the same effect as the substance.
International Cooperation and Exchange:
With the continuous development of globalization and informatization, international cooperation and exchange are playing an increasingly important role in promoting drug research and market expansion. Through cooperation and exchange with international peers, research results can be shared, technological innovation can be promoted, and market expansion can be achieved.
What Are The Side Effects And Adverse Reactions Of Ivermectin Powder?
1.Common side effect
Gastrointestinal reactions:
Symptoms such as nausea, vomiting, diarrhea, and abdominal pain may occur. These reactions are usually mild and may gradually alleviate with prolonged medication time.
Neurological reactions:
Symptoms such as headache, dizziness, tremors, and sleep disturbances may occur. These reactions may be related to the mild effects of the drug on the nervous system.
Skin reactions:
Skin symptoms such as rash, itching, and urticaria may occur. For topical creams such as Soolantra, it may also cause skin irritation and tingling sensation, especially at the beginning of use.
Eye discomfort:
When using this product, if the medication comes into contact with the eyes or the surrounding area, it may cause eye irritation and discomfort, including itching, burning sensation, and increased tears.
Other reactions:
There may also be immune reactions such as fever, lymph node enlargement, and symptoms such as hypotension.
2.Occasional adverse reactions
Joint and muscle pain:
Some patients may experience symptoms such as joint pain and muscle pain.
Lymph node swelling and pain:
There may be swelling of lymph nodes.
Edema:
Some patients may experience symptoms of edema.
Electrocardiogram changes:
Transient non-specific electrocardiogram changes may occur.
3.The reactions of special populations
Pregnant and lactating women: This product is contraindicated for pregnant and lactating women as the medication may have adverse effects on the fetus or infant.
Allergic reactions: Although not common, some patients may experience allergic reactions to ivermectin. Allergic reactions may manifest as symptoms such as skin itching, redness, swelling, urticaria, and difficulty breathing. Once an allergic reaction occurs, medication should be stopped immediately and medical attention sought for professional assistance.
FAQ
1. What is ivermectin powder?
It is an unprocessed pure raw drug, mainly used for the production of veterinary deworming agents. **It is strictly prohibited to use it directly on humans or animals.
2. What is the main purpose?
It is strictly used for legal industrial production, such as the preparation of veterinary premixes and external preparations, and needs to be processed under professional equipment and in compliance with relevant procedures.
3. Can it be used for treating human diseases?
Absolutely not allowed. The original powder has a high concentration and lacks safety dosage control. Self-use can easily lead to poisoning or even death. Human medication should use strictly purified and packaged medical preparations.
4. What are the requirements for storage?
It should be stored in a sealed container, protected from light and in a dry place. Keep it away from heat sources and children. It should be managed by professionals to prevent misuse and contamination.
5. What should be noted when making a purchase?
Only qualified manufacturers or institutions can make the purchase. Legal proof must be provided. Personal purchases are all illegal and carry serious security and legal risks.
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