Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of matrixyl 3000 peptide in China. Welcome to wholesale bulk high quality matrixyl 3000 peptide for sale here from our factory. Good service and reasonable price are available.
Matrixyl 3000 peptide consisting of Palmitoyl Tripeptide‑1 and Palmitoyl Tetrapeptide‑7. As a matrikine‑type ingredient, it supports dermal matrix maintenance with good compatibility for anti‑aging skincare formulas. Proper temperature and pH control are required to retain peptide activity. As a reliable peptide manufacturer, Bloomtechz delivers qualified raw materials with full quality reports and professional one‑on‑one technical support for your cosmetic R&D.
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Matrixyl 3000 COA
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| Certificate of Analysis | ||
| Compound name | Matrixyl 3000 | |
| Grade | Pharmaceutical grade | |
| CAS No. | N/A | |
| Quantity | 19g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090055 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure | N/A | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.50% |
| Loss on drying | ≤1.0% | 0.68% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.45% |
| Single impurity | <0.8% | 0.78% |
| Total microbial count | ≤750cfu/g | 98 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 570ppm |
| Storage | Store in cool, dark place or refrigerator | |
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The key active ingredients in Matrixyl 3000 Peptide are listed in the INCI nomenclature as palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7.
"Matrikines" refer to short peptide fragments derived from extracellular matrix proteins that transmit "repair and reconstruction" signals to skin fibroblasts. Specifically, the sequence of Palmitoyl Tripeptide-1 is glycine-histidine-lysine (Gly-His-Lys, or GHK), which was first discovered in human plasma albumin in 1973; the sequence of Palmitoyl Tetrapeptide-7 is glycine-glutamine - proline - arginine (Gly-Gln-Pro-Arg), which is homologous to immunoglobulin-related peptides and focuses on regulating inflammatory responses. These two peptide chains work synergistically to form a dual-pathway mechanism of "promoting collagen synthesis + anti-inflammatory soothing."In terms of its commercial form, it is typically supplied as a viscous,


gel-like aqueous solution containing glycerin, water, butylene glycol, carbomer, and polysorbate-20. It is highly water-soluble and can be easily incorporated into aqueous formulations. The N-termini of both peptide chains are modified with palmitic acid; this lipidation design significantly enhances the molecule's lipophilicity, facilitating the penetration and retention of the active ingredient in the stratum corneum-a common technical characteristic of the "palmitoyl peptide" family.
Based on currently published research, in vitro experiments indicate that this dipeptide system promotes the synthesis of matrix components such as Type I and Type III collagen by skin fibroblasts;
human clinical trials conducted by the manufacturer also report improvements in cosmetic indicators such as wrinkle depth and area following sustained use.It should be noted that these data are derived from specific experimental conditions and research samples; actual results may vary depending on formulation, concentration, skin type, and usage habits, and should be viewed with a rational perspective.
As a professional manufacturer specializing in cosmetic peptide ingredients, Bloomtechz has long supplied blended raw materials based on the same INCI active ingredients as Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, and adheres to the same batch purity, content, and microbial control standards as leading international suppliers.

Bloomtechz provides compliant ingredients verified by an independent quality control system, helping brands achieve greater flexibility in cost and supply chain choices while ensuring efficacy and safety.


Matrixyl 3000 Peptide and similar ingredients are used in virtually all leave-on anti-aging skincare products. In serums, it is often combined with hyaluronic acid, niacinamide, and other ingredients to improve fine lines and skin texture; in creams and lotions, it functions as a signaling peptide, working synergistically with moisturizing and reparative active ingredients; it is also commonly found in formulations targeting localized wrinkles, such as eye creams and neck creams. Due to its good water solubility and flexible incorporation window, it can be incorporated into oil-in-water emulsions as well as simplified systems like gels and essence waters, making it suitable for both day and night products.In terms of incorporation, peptides are generally heat-sensitive;
the industry standard practice is to add them during the cooling phase of formulation (typically at temperatures no higher than 60°C) to avoid prolonged exposure to high temperatures that could damage the peptide chain structure.The typical usage rate of commercially available raw material solutions in formulations is approximately 1%–8%; most suppliers recommend 3%–4% to achieve a balanced cost-effectiveness and performance. The specific usage rate must be determined comprehensively based on product positioning, total active ingredient content, and stability testing. This ingredient exhibits excellent compatibility when blended with hyaluronic acid, vitamin C derivatives, niacinamide, ceramides, and other peptides, making it a "versatile" anti-aging option in the eyes of formulators.


Bloomtechz fully understands that there is still a gap between "raw materials and finished products" in terms of formulation and manufacturing processes. Therefore, in addition to ensuring a stable supply, we provide one-on-one technical support to each client to help shorten the time from sample production to market launch.As a cosmetic ingredient, the safety of Matrixyl 3000 Peptide type ingredients has been verified through long-term market use and authoritative evaluations. The Cosmetic Ingredient Review (CIR) Expert Panel, in its safety assessment of palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, and related derivatives, concluded that they are safe when used in cosmetics at current concentrations and under current usage conditions.
Results from multiple human repeated irritation patch tests (HRIPT) indicate that this ingredient is non-sensitizing and well-tolerated; publicly available data show that patch tolerance remains good even at high test concentrations.It is important to note that the type ingredients fall under the category of cosmetic ingredients, not pharmaceuticals; their claims should be limited to the scope of legitimate cosmetic claims, such as improving skin appearance and maintaining skin condition.Bloomtechz consistently adheres to the principles of compliance and transparency in ingredient promotion. Every batch of ingredients delivered to customers is accompanied by a complete Certificate of Analysis (COA) that accurately reports metrics such as purity,

concentration, microbial content, and heavy metals, for customer review and regulatory filing purposes, thereby mitigating the risks of exaggerated claims and regulatory non-compliance at the source.
References
[1] Sederma(Croda)· MATRIXYL 3000 Product Information File
[2]Cosmetic Ingredient Review (CIR) Expert Panel · Safety Assessment of Tripeptide-1, Hexapeptide-12, their Metal Salts and Fatty Acyl Derivatives, and Palmitoyl Tetrapeptide-7 as Used in Cosmetics
[3] Pickart L · The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging
[4]The INKEY List · What is Matrixyl 3000? The Science Behind INKEY's Most-Used Peptide
[5] PeptideJournal · Matrixyl Clinical Studies: Anti-Wrinkle Evidence
FAQ
Q1: What are the key contraindications for the product during formulation, and which active ingredients are not recommended for use in combination with it?
A: The core active ingredients in the product are palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. with an overall pH tolerance range of 3.0–8.0. Strong oxidizing agents and systems containing extremely strong acids or bases should be avoided. High-concentration free-acid forms of vitamin C require compatibility stability testing, and blending with strong bleaching agents is not recommended. Peptides are heat-sensitive substances; the recommended addition temperature should be controlled at ≤60°C, and prolonged boiling at high temperatures is prohibited. Bloomtechz offers comprehensive technical support, providing customers with one-on-one formulation evaluation services.
Q2: Matrixyl 3000 Peptide has strict storage requirements. If it is exposed to high temperatures for a short period during shipping, will the ingredient become completely ineffective and need to be discarded?
A: Short-term temperature fluctuations will not directly cause the ingredient to become completely inactive; however, prolonged exposure to high temperatures or repeated cycles of heating and cooling will accelerate peptide chain degradation, reduce active ingredient content, and may also cause discoloration of the formulation. If the product is exposed to high temperatures for a short period during shipping, three re-inspections-activity content, appearance, and microbiological testing-must be conducted upon arrival. The decision on whether the product can still be used should be based on the test results; it should not be determined solely by subjective visual inspection. As a professional manufacturer, Bloomtechz provides recommendations for protecting raw materials during transportation and can assist customers in implementing post-delivery re-inspection protocols.
Q3: Both Matrixyl 3000 Peptide and Acetyl Hexapeptide-8 (Argireline) are anti-aging peptides. Can they be used as direct substitutes for one another?
A: The two cannot be directly substituted for one another, as their mechanisms of action differ fundamentally. It is a matrix signaling peptide that primarily acts on fibroblasts, focusing on extracellular matrix repair; Acetyl Hexapeptide-8 is a neurotransmitter-modulating peptide that is more effective at smoothing expression lines. The two are not in competition with each other and are often combined in formulations to achieve synergistic effects. Bloomtechz supplies a wide range of cosmetic peptide ingredients and, leveraging its proprietary manufacturing processes, supports sample testing.
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