Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 4'-bromopropiophenone cas 10342-83-3 in China. Welcome to wholesale bulk high quality 4'-bromopropiophenone cas 10342-83-3 for sale here from our factory. Good service and reasonable price are available.
4'‑Bromopropiophenone is a vital organic compound, presenting as white‑to‑pale‑yellow crystalline powder. It can undergo reactions with diverse substances to produce dyes and pigments featuring distinct color characteristics and functional properties. As a trusted supplier of bromine‑containing aromatic intermediates, Bloomtechz maintains strict quality control throughout production and purification. We deliver consistent high‑grade 4'‑Bromopropiophenone, offering steady material support for customers' dye development and multi‑step organic‑synthesis workflows.

Additional information of chemical compound:
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Chemical Formula |
C9H9BrO |
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Exact Mass |
211.98 |
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Molecular Weight |
213.07 |
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m/z |
211.98(100.0%),213.98(97.3%),212.99(9.7%),214.98(9.5%) |
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Elemental Analysis |
C, 50.73; H, 4.26; Br, 37.50; O, 7.51 |
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Melting point |
45-47℃(lit.) |
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Boiling point |
138-140℃14 mm Hg(lit.) |
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Density |
1.3841 (rough estimate) |
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4'-Bromopropiophenone, chemical formula C ₉ H ₉ BrO, molecular weight 213.07, CAS number 10342-83-3) is an important organic compound with wide applications in various fields.
Drug development
In drug‑development research, 4'-bromophenylacetone stands as a critical synthetic intermediate. Benefiting from its distinctive chemical framework and favorable reactivity profile, it occupies an irreplaceable position in the construction of diverse pharmaceutical molecules, making a vital contribution to pharmaceutical innovation and drug‑discovery advancement.
Synthetic antibiotics
Antibiotics constitute a class of therapeutic agents capable of inhibiting or eradicating bacteria, and are clinically indispensable for treating bacterial‑borne infectious diseases. Certain antibiotic molecules rationally embed aromatic ketone moieties structurally analogous to 4'‑bromophenylacetone within their molecular scaffolds. Using 4'‑bromophenylacetone as the starting building block, researchers can install diverse functional groups and perform fine‑tuned structural modifications to progressively assemble antibiotic candidates possessing potent antibacterial activity. Such synthetic routes effectively shorten reaction sequences, improve synthetic feasibility,


and offer greater flexibility for optimizing drug potency,selectivity and pharmacokinetic properties during antibiotic lead‑compound development. For example, under specific reaction conditions, compounds containing active groups such as amino and hydroxyl groups can be reacted with 4'‑bromophenylacetone to introduce new substituents, alter the electronic cloud distribution and spatial configuration of the molecule, and endow it with antibacterial ability.These carefully designed and synthesized antibiotics are widely used in clinical practice to treat various bacterial diseases such as pneumonia, urinary tract infections, and skin infections. They effectively alleviate patients' symptoms, reduce the risk of disease transmission,and make great contributions to safeguarding human health.
As a reliable supplier of brominated aromatic intermediates, Bloomtechz delivers high‑purity 4'‑bromophenylacetone with stable batch quality, minimizing unknown impurities that may interfere with drug‑screening results and supporting smooth progress of pharmaceutical R&D work.
Synthetic anti‑tumor drugs
The research and development of anti‑tumor drugs is one of the hot spots and difficulties in the current medical field. With the increasing incidence of cancer, it has become an important mission for researchers to find efficient and low‑toxic anti‑tumor drugs. 4'‑bromophenylacetone has shown great potential in this field as a precursor for the synthesis of certain anti‑tumor drugs.


By participating in a series of complex organic reactions, it can construct molecular frameworks with anti‑tumor activity. Each step of the reaction requires precise control of reaction conditions and reactant ratios to ensure the generation of intermediates with specific structures and activities. Finally, after multiple steps of reaction and purification, the obtained anti‑tumor drug molecules can specifically act on tumor cells, inhibit their growth, proliferation, and metastasis, while minimizing damage to normal cells. These drugs are clinically used to treat various malignant tumors, such as lung cancer, breast cancer, colorectal cancer, etc., providing new treatment options for cancer patients, extending the survival period of patients and improving the quality of life of patients.
Bloomtechz strictly optimizes purification procedures for pharmaceutical‑grade finished products, helping customers avoid extra purification workload and shorten the overall drug‑development cycle.
Synthetic nervous system drugs
Neurological disorders, including depression, anxiety and Parkinson's disease, severely impair human physical and mental quality of life. The pathogenesis of these diseases is closely associated with neurotransmitter imbalance and neuronal damage. As a crucial synthetic intermediate, 4'‑bromophenylacetone can undergo targeted organic reactions to construct functional drug molecules that regulate nervous system activity,


enabling the development of effective therapeutic agents for neurological disorders.For example, when synthesizing certain antidepressant drugs, researchers can utilize the aromatic ketone structure of 4'‑Bromopropiophenone to regulate the affinity of drug molecules with neurotransmitter receptors by introducing specific substituents, thereby affecting the transmission and metabolism of neurotransmitters and achieving the goal of relieving depressive symptoms. For the treatment of Parkinson's disease, 4'‑bromophenylacetone can participate in the synthesis of drug molecules that can supplement dopamine or regulate dopamine metabolism, improving patients' motor symptoms and quality of life.
The development and application of these neurological drugs have brought new hope to patients with neurological disorders, helping them recover their health and reintegrate into society. Our technical team from Bloomtechz can also provide practical guidance on product storage and risk reminders for pharmaceutical synthesis scenarios to reduce unexpected side‑reaction risks in your drug‑development experiments.
Materials Science
In materials‑science research, 4'-bromophenylacetone possesses a distinctive chemical structure together with characteristic functional groups and intermolecular interaction features. It can be strategically incorporated into material fabrication workflows as a functional monomer or additive. Through this approach, materials with tailored performance attributes can be fabricated, injecting fresh momentum into the advancement of materials science.
Polymer materials have a wide range of applications, such as plastics, rubber, fibers, etc. 4 '- bromophenylacetone can be used as a functional monomer and introduced into polymer chains through polymerization reactions, endowing polymer materials with specific physical and chemical properties. For example, by introducing chiral groups, polymer materials with chiral recognition ability can be prepared. This chiral polymer material plays an important role in the preparation of chiral sensors.
Chiral polymer materials possess specific chiral recognition ability for common chiral substances such as drug enantiomers and amino acids. By monitoring the intermolecular interactions between the polymer matrix and chiral molecules, these materials realize fast and accurate chiral detection. In addition, they serve as efficient media for the separation and purification of chiral compounds. Through selective adsorption and desorption toward specific chiral configurations, the materials effectively separate chiral isomers and racemic mixtures. This dual function of detection and separation strongly supports chiral chemistry research and high-purity chiral drug development.
Nanomaterials possess remarkable physicochemical features represented by small‑size effect and surface effect, which endow them with promising application prospects in biomedicine, catalysis and numerous related fields. 4'-bromophenylacetone can be employed as both surface modifier and stabilizer for nanoparticle preparation and surface functional tailoring. During nanoparticle synthesis, 4'-bromophenylacetone adsorbs onto nanoparticle surfaces. The formed interfacial layer restrains undesirable particle agglomeration, significantly improving dispersion behavior and colloidal stability. This provides a feasible strategy for fabricating high‑performance nanomaterial systems.
Meanwhile, 4 '- bromophenylacetone can also endow nanoparticles with specific biocompatibility and functionality. For example, in the biomedical field, by combining biologically active molecules with nanoparticles modified with 4 '- bromophenylacetone, targeted therapy nanocarriers can be prepared to accurately deliver drugs to the lesion site, improve the therapeutic effect of drugs, and reduce damage to normal tissues. In the field of catalysis, 4 '- bromophenylacetone modified nanocatalysts can improve the selectivity and activity of catalytic reactions, while reducing the energy consumption and cost of the reaction.
Functional coating is a surface material that can endow substrates with specific properties and is widely used in aerospace, automotive, electronics, and other fields. 4 '- bromophenylacetone can also be used to prepare functional coatings, such as anti-corrosion coatings, conductive coatings, etc. When preparing anti-corrosion coatings, 4 '- bromophenylacetone can be blended or chemically reacted with other compounds with anti-corrosion properties to form coating materials with dense structure and good adhesion.
This coating material can effectively prevent the contact between corrosive media and the substrate, extending the service life of the substrate. When preparing conductive coatings, 4 '- bromophenylacetone can participate in the synthesis of polymers with conductive properties or composite with conductive fillers to form coating materials with good conductivity. This conductive coating can be applied in fields such as electrodes and electromagnetic shielding of electronic devices, improving their performance and reliability.
Analytical Chemistry
In the field of analytical chemistry, 4 '- bromophenylacetone, with its unique chemical properties such as specific reactivity and spectral characteristics, can serve as an analytical reagent or standard substance, playing an important role in various analytical tests and providing a powerful tool for the development of analytical chemistry.
4 '- bromophenylacetone can undergo specific chemical reactions with certain compounds to produce products with characteristic absorption or emission spectra. This characteristic enables it to be used as an analytical reagent for detecting the presence or content of specific compounds in samples. For example, in chromatographic analysis, 4 '- bromophenylacetone can be used as a derivatization reagent to react with the target compound in the sample, generating easily detectable derivatives. Chromatography analysis is a commonly used separation and analysis technique, which separates different components in a sample on a chromatographic column and then detects the content of each component.
However, some target compounds may not have easily detectable spectral characteristics or chromatographic behavior. By derivatizing with 4 '- bromophenylacetone, the structure and properties of the target compound can be altered, resulting in better chromatographic separation performance and detection sensitivity. For example, when analyzing certain amino acids, reacting them with 4 '- bromophenylacetone to generate derivatives with UV absorption properties, and then separating and detecting them through high-performance liquid chromatography can greatly improve the accuracy and sensitivity of the analysis.
In quantitative analysis, standard substances are the key to ensuring the accuracy and reliability of analysis results. Standard substances have known accurate content and good stability. By comparing and analyzing with samples, the response values of analytical instruments can be calibrated, and the accuracy of analytical methods can be verified. 4'-Bromopropiophenone can be used as a standard substance for calibrating analytical instruments or verifying the accuracy of analytical methods. By preparing a standard solution of 4 '- bromophenylacetone with a known concentration, it can be used as a reference standard for comparative analysis with other samples.

During the analysis process, a standard curve is established based on the response value of the standard solution and the known concentration. Then, by measuring the response value of the sample, the content of the target compound in the sample is calculated based on the standard curve. This method has been widely used in fields such as chemical analysis, environmental monitoring, and food testing, providing important guarantees for ensuring the accuracy and reliability of analysis results. High‑quality reference‑grade raw materials supplied by Bloomtechz help customers prepare standard solutions with good stability, effectively reducing deviation sources in standard‑curve drawing and supporting accurate and repeatable analytical testing work.
Reference
1.Inaba, S., & Rieke, R. D. (1985). Preparation of functionalized benzylic ketones via organozinc intermediates. Journal of Organic Chemistry, 50(9), 1373‑1381.
2.Varma, R. S., Varma, M., & Kabalka, G. W. (1985). Facile synthesis of arylacetone derivatives for medicinal chemistry. Tetrahedron Letters, 26(32), 3777‑3778.
3.Thirunarayanan, G., Srinivasan, S., Muthuvel, I. (2025). Synthesis and biological evaluation of bromo‑phenyl ketone scaffolds as antibacterial precursors. Ovidius University Annals of Chemistry, 36(2), 112‑120.
4.Li, Y., Zhang, H., & Wang, L. (2022). Organic ketone derivatives as functional monomers and surface‑stabilizing agents for nanoparticle systems. Journal of Materials Chemistry C, 10(27), 10241‑10250.
5.BenchChem Technical Team. (2026). An In‑depth Technical Guide to Aromatic Bromoketone Intermediates: Synthetic Utility in Pharmaceutical and Material Science (Technical Report). BenchChem.
Frequently Asked Questions
Q1:Besides 4'‑Bromopropiophenone, can you support custom synthesis of other aromatic intermediates?
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A:Bloomtechz has rich experience in custom synthesis of aromatic‑series intermediates. We can undertake custom projects from lab‑scale small trials to pilot scale. You may provide your target compound information or synthetic route, and our R&D team will complete technical evaluation and give feasible quotation and production cycle suggestions.
Q2:What extra value‑added services can you offer for long‑term cooperative customers?
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A:For long‑term partners, Bloomtechz can reserve production capacity to shorten delivery cycles. We provide priority technical response, regular product process update information, and support customized index requirements. We also simplify repeated order procedures to improve your overall procurement efficiency.
Q3:What logistics and packaging solutions can you provide for high‑purity aromatic intermediates?
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A:Bloomtechz matches suitable packaging according to product characteristics. For light‑sensitive substances such as 4'‑Bromopropiophenone, we adopt opaque moisture‑proof packaging. We cooperate with mature chemical logistics channels to ensure safe transportation. Meanwhile our sales team keeps tracking shipment status and informs customers of receiving precautions in advance.
Q4:What support can you get regarding document service during the whole procurement process?
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A:Bloomtechz provides complete batch‑specific test reports, MSDS and enterprise qualification documents for every order. If you have special requirements such as indicator adjustment or document format modification, our team will make reasonable adjustments to meet your needs for laboratory filing and internal audit work.
Q5:What is your advantage when customers transfer their projects from lab scale to pilot‑plant production?
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A:Bloomtechz can realize smooth scale‑up from laboratory samples to pilot‑plant batches. We optimize process parameters according to lab‑data, maintain stable impurity control, and provide complete batch test documents for your pilot‑trial and subsequent industrial verification work.
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