8-Hydroxyquinoline Powder CAS 148-24-3

1. It is widely used for the determination and separation of metals. Precipitant and extractant for precipitation and separation of metal ions can be complexed with the following metal ions: Cu+ 2,Be+ 2,Mg+ 2,Ca+ 2,Sr+ 2,Ba+ 2,Zn+ 2,Cd+ 2,Al+ 3,Ga+ 3,In+ 3,Tl+ 3,Yt+ 3,La +3,Pb+ 2,B+ 3,Sb+ 3,Cr+ 3,MoO+ 22,Mn+ 2,Fe+ 3,Co+ 2,Ni+ 2,Pd+ 2,Ce+ three.

2. As a pharmaceutical intermediate, it is a raw material for the synthesis of kexielin, chloroiodoquinoline and paracetamol, and also a dye and pesticide intermediate. This product is an intermediate of halogenated quinoline anti amoeba drugs, including quiniodoform, chloroiodoquinoline, diioquinoline, etc.

These drugs exert anti amebic effects by inhibiting intestinal commensal bacteria, and are effective against amebic dysentery, and have no effect on extraintestinal amoeba protozoa. It is reported abroad that this kind of drug can cause subacute spinal optic neuropathy, so this drug has been banned in Japan and the United States. The disease caused by diioquinoline is less common than that caused by chloroiodoquinoline. 8-Hydroxyquinoline powder is also an intermediate of dyes and pesticides. Its sulfate and copper salt are excellent antiseptics, disinfectants and fungicides. This product is a complexometric indicator for chemical analysis.

3. As a complexing agent and extractant for precipitation and separation of metal ions, it can interact with Cu + 2, be + 2, Mg + 2, Ca + 2, Sr + 2, Ba + 2, Zn+ 2,Cd+2,Al+3,Ga+3,In+3,Tl+3,Yt+3,La +3,Pb+2,B+3,Sb+ 3,Cr+3,MoO+ 22. Mn + 2, Fe + 3, CO + 2, Ni + 2, PD + 2, CE + 3, etc. Standard for determination of heterocyclic nitrogen by organic microanalysis, organic synthesis. It is also an intermediate of dyes, pesticides and haloquinoline anti amoeba drugs. Its sulfate and copper salt are excellent antiseptics.

4. Adding epoxy resin adhesive can improve the bonding strength and heat aging resistance to metals (especially stainless steel), and the dosage is generally 0.5-3 phr. It is an intermediate of haloquinoline anti amoeba drugs, as well as an intermediate of pesticides and dyes. It can be used as mold inhibitor, industrial preservative, stabilizer of polyester resin, phenolic resin and hydrogen peroxide, and also as a complexometric indicator for chemical analysis.

5. This product is an intermediate of halogenated quinoline drugs, and also an intermediate of dyes and pesticides.

Its sulfate and copper salt are excellent antiseptics, disinfectants and fungicides. The maximum allowable content (mass fraction) in cosmetics is 0.3%. Sunscreen products and products for children under 3 years old (such as talcum powder) are prohibited, and the product label shall be marked with "prohibited for children under 3 years old". The mass fraction of 8-hydroxyquinoline in lotion was 0.001% ~ 0.02% when treating bacterial infected skin and bacterial eczema. It is also used as disinfectant, antiseptic and bactericide, and has strong anti mold effect.The content (mass fraction) of 8-hydroxyquinoline potassium sulfate used in skin care cream and lotion is 0.05% ~ 0.5%.

1. Intermediate of anti amoebic drugs
It is an important intermediate for halogenated quinoline anti amoebic drugs, such as quinolone, chloroiodoquinol, diiodoquinoline, etc. These drugs exert anti amoebic effects by inhibiting intestinal commensal bacteria and are effective against amoebic dysentery. However, in recent years, it has been reported abroad that such drugs may cause subacute spinal optic neuropathy. Therefore, some drugs have been banned in Japan and the United States. Nevertheless, its position in the synthesis of anti amoebic drugs remains important.

2. Synthesis of other drugs
In addition to anti amoebic drugs, 8-Hydroxyquinoline powder can also be used to synthesize various other drugs. For example, it can be used as a raw material for the synthesis of drugs such as Ke Xie Li Ning and Pu Chi Ming. In addition, studies have shown that it has various pharmacological effects such as anti-cancer, antiviral, antibacterial, and hemostatic properties. For example, it can inhibit the proliferation and differentiation of tumor cells, and has a certain therapeutic effect on breast cancer, colon cancer and other malignant tumors. These findings provide possibilities for further applications in the field of medicine.

3. Fluorescent probes and cell labeling
It can also be used as a fluorescent probe in fields such as live cell imaging and cell labeling. Its unique fluorescence properties make it have broad application prospects in biomedical research. By labeling cells or biomolecules, researchers can more intuitively observe their behavior and changes within the organism, thereby gaining a deeper understanding of the mechanisms of biological processes.

1. Plant growth regulators
It can be used as a plant growth regulator and has the effect of accelerating the healing of grafting incisions. In agricultural production, grafting is a commonly used reproductive technique, but the healing speed of grafting incisions often affects the success rate of grafting. Adding can significantly promote the healing of grafting incisions, increase the success rate of grafting, and bring convenience to agricultural production.

2. Preservatives, disinfectants, and mold inhibitors
The sulfate and copper salts of this substance are excellent preservatives, disinfectants, and mold inhibitors. In pesticide formulations, these compounds can effectively extend the shelf life of pesticides and prevent them from deteriorating during storage and use. At the same time, they can also be used for disinfection and anti mold treatment of crop surfaces, protecting crops from the invasion of pests and diseases.

1. Dye intermediates
It is an important intermediate in the dye industry. It can be used to synthesize various dyes with specific colors and properties. These dyes are widely used in the coloring process of industries such as textiles, leather, and papermaking, providing a wide range of color choices for these industries. By introducing high-performance intermediate materials such as 8-hydroxyquinoline, the color vividness, fastness, and weather resistance of dyes can be significantly improved.

2. Pigments and paint additives
In addition to serving as a dye intermediate, 8-hydroxyquinoline can also be used to prepare certain pigments and coating additives. These additives can improve the dispersibility, stability, and weather resistance of pigments and coatings, enhancing their usability. For example, adding an appropriate amount of 8-hydroxyquinoline to coatings can enhance their adhesion and corrosion resistance, and extend their service life.

1. Complexation titration indicator
It is a commonly used complexometric titration indicator in chemical analysis. It can form stable complexes with various metal ions and indicate the arrival of the titration endpoint through color changes. This indicator has the advantages of high sensitivity and good accuracy, and has broad application prospects in fields such as environmental monitoring and food safety.

2. Metal ion precipitants and extractants
In addition to serving as a complexometric titration indicator, it can also be used for precipitation and separation of metal ions. 

At the same time, it can also be used as an extractant to extract specific metal ions from complex systems. These characteristics play an irreplaceable role in metal ion analysis, separation, and recovery.

3. Chromatographic analysis reagents
In chromatographic analysis, 8-Hydroxyquinoline powder is also commonly used as a reagent. It can form complexes or coordination compounds with certain compounds, thereby altering their retention time or migration rate on the chromatographic column. This characteristic makes it uniquely valuable for the separation and purification of complex samples.

1. Optoelectronic materials
It has broad application prospects in the field of optoelectronic materials. It can be used to prepare materials such as photovoltaic materials, conductive polymers, photosensitizers, etc. For example, complexes formed with certain metal ions have good luminescent properties and can be used to prepare electronic products such as OLED displays. In addition, it can also be used to prepare sensor materials such as humidity sensors, utilizing their strong water absorption to detect changes in environmental humidity.

2. Battery materials
In the field of battery materials, it has also demonstrated unique application value. It can serve as a stabilizer or flame retardant for electrolytes, improving the safety and cycling performance of batteries. By combining coordination with metal ions in the electrolyte, the dissolution of electrode materials can be inhibited, and a stable SEI film (solid electrolyte interface facial mask) can be formed on the electrode surface, thus reducing the interface impedance and improving the cycle life. In addition, it can also be used to improve the stability of positive electrode materials and suppress lithium dendrite growth.

3. Catalytic materials
8-Hydroxyquinoline and its derivatives also have certain potential applications in the field of catalytic materials. They can form complexes or coordination compounds with transition metals and be used as catalysts in various chemical reactions. For example, certain 8-hydroxyquinoline-metal complexes exhibit excellent oxygen reduction reaction (ORR) catalytic activity and can be used in energy conversion devices such as fuel cells.

1. RNA synthesis inhibitors
It can also be used as an inhibitor of RNA synthesis. It can inhibit the RNA synthesis process of certain microorganisms, thereby exerting antibacterial effects. This characteristic makes it of certain application value in microbiology research and antibacterial drug development.

2. Preservatives and disinfectants
In addition to the aforementioned applications, 8-Hydroxyquinoline powder and its derivatives can also be used as preservatives and disinfectants. They can inhibit the growth and reproduction of microorganisms, extending the shelf life of products. These compounds are widely used in the fields of food, cosmetics, medicine, etc. for the preservation and disinfection of products.

3. Rare earth complex thermal stabilizer
Research by Baotou Rare Earth Research Institute shows that ternary complexes made with rare earths and stearic acid have advantages such as antibacterial and strong thermal stability as heat stabilizers. This type of heat stabilizer can be used in fields such as sheet metal, profiles, and pipes to improve the thermal stability and weather resistance of materials. This discovery provides new ideas for further applications in the field of materials science.