Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of n-vinyl-2-pyrrolidone cas 88-12-0 in China. Welcome to wholesale bulk high quality n-vinyl-2-pyrrolidone cas 88-12-0 for sale here from our factory. Good service and reasonable price are available.
N-vinyl-2-pyrrolidone (NVP) is a colorless to pale yellow transparent liquid with a faint amine-like characteristic odor. As an important organic compound, its molecular structure contains both vinyl groups and a strongly polar imide ring, which endows it with extremely high reactivity and excellent polymerization ability. It can be used for both homopolymerization and copolymerization with various monomers. Due to its excellent water solubility, low toxicity, and good carrying properties, the main application of NVP lies in the synthesis of its homopolymer polyvinylpyrrolidone (PVP). This high-molecular polymer is used as a drug sustained-release carrier, tablet binder, and blood volume enhancer in the pharmaceutical field; in the daily chemical industry, it is an indispensable film-forming agent and stabilizer in hair gels and skin care products. Moreover, it is widely used in UV light-curable resins, special coatings, adhesives, and as an efficient reactive solvent and intermediate for fine chemicals, demonstrating extremely broad application value.
|
Chemical Formula |
C6H9NO |
|
Exact Mass |
111 |
|
Molecular Weight |
111 |
|
m/z |
111 (100.0%), 112 (6.5%) |
|
Elemental Analysis |
C, 64.84; H, 8.16; N, 12.60; O, 14.39 |
|
|
|
1. Acetylene method:
As early as 1943, W Reppe adopted it. The reaction mechanism is as follows:
According to the reaction mechanism, the reaction can be divided into two stages. In the first stage, pyrrolidone potassium salt is produced, which is the catalyst for the subsequent two-step reaction. At this stage, in order to prevent the ring opening of pyrrolidone from generating the by-product potassium 4-aminobutyrate, vacuum and nitrogen injection are commonly used for dehydration. This stage is carried out intermittently. Once the dehydration is complete, the second stage can be carried out continuously. The one-way conversion of pyrrolidone was 66.6% and the selectivity was 90%. The continuous operation can be realized by replacing potassium hydroxide with alkali metal. The one-way conversion of pyrrolidone is 47% ~ 62%, the selectivity is 90%, and the total yield of NVP is over 90%.
2. Transesterification and ether exchange:
In DMF solvent, in the presence of pdcl2-lic1 composite catalyst, pyrrolidone was exchanged with t-ether, and NVP was produced in 88.5% yield at 100C reaction temperature. In the presence of pdc12 LiCl catalyst, pyrrolidone was reacted with vinyl acetate to obtain
NVP, yield 87%, and the product is not easy to purify.
3.1, γ- Butyrolactone amine hydrolysis:
γ ~ The aminolysis reaction between butyrolactone and ethanolamine is similar to the reaction between r-butyrolactone and ammonia, that is, the oxygen-containing cyclic compound is converted into the ammonia containing cyclic compound, but the raw material ammonia (amine) is different. The research methods of hatada et al are also applicable to γ - The amination reaction of butyrolactone, that is to say, some cation exchanged Y-type molecular sieves γ- The aminolysis reaction between butyrolactone and ethanolamine has catalytic activity. Kulkarni also has similar research reports.
The reaction product is hydroxyethyl pyrrolidone (NHP), and the cation exchange molecular sieve used can be mGy, KY, cay, etc. the reaction temperature is reported to be about 220c in the literature, and the conversion rate of reaction raw materials can reach above 90%, but the NHP selectivity is only about 50%.
3.2, γ- Butyrolactone indirect dehydration halogenation method:
The halogenation method is to make the hydroxyl group in the NHP molecule be replaced by halogenating agent to generate haloethylpyrrolidone, and then the product NVP is obtained by the heat elimination reaction of haloethylpyrrolidone. The halogenating agents commonly used are hydrogen chloride, sulfoxide chloride, etc. The indirect dehydration method requires halogenation first and then dehydrohalogenation Compared with the direct method, the reaction steps are increased, thus reducing the utilization of raw materials, and a large amount of alkali is consumed in the reaction process.
3.3, γ- Catalytic method for direct dehydration of butyrolactone:
γ- The direct dehydration of butyrolactone catalyzed by γ - The stable intermediate product NHP was prepared by amination of butyrolactone and then dehydrated directly. The key of NHP dehydration is to prepare suitable catalyst. W. Schnizer et al. 9] reported that under the reaction conditions of 300-340c, 1.33 x 10Pa and 500-4000h-1 gas space flow rate, N-Vinyl-2-Pyrrolidone with a yield of 64% can be obtained by using active aluminum as dehydration catalyst for gaseous NHP reactants. The low NHP conversion rate is mainly due to the poor stability of active aluminum catalyst, which is easy to be deactivated and must be operated at low pressure. Pine scikuo et al. Two or more kinds of oxides containing lead, tin, titanium, silicon and hafnium have been developed as dehydration catalysts for catalyst improvement. Zirconia, tin oxide and other composite catalysts have both acidic and basic sites, with strong catalytic activity and high NVP selectivity, up to 90%. Moreover, the catalyst has moderate acidity and alkalinity, which is suitable for catalytic dehydration of NHP. The surface of the catalyst has no strong acid center, and the surface is not easy to form coke, therefore, the catalyst has long service life, easy regeneration, and can be reacted under normal pressure, so it has industrial prospects.
N-vinylpyrrolidone (NVP) is an important organic compound with the chemical formula C ₆ H ₉ NO. It is a colorless liquid that is miscible with various solvents such as water, ethanol, and ether, and is easily copolymerized with other ethylene compounds. Its unique chemical properties and excellent reactivity make it widely applicable in multiple fields. This article will provide a detailed introduction to the specific applications of N-vinylpyrrolidone in various fields.
(1) UV curable coating active diluent
In the plastic industry, NVP is often used as an active diluent for UV curable coatings. In UV curable coating systems, oligomers usually have high viscosity and require the addition of monomers to adjust viscosity. NVP is one of the important active diluents. It has good diluency, which can effectively reduce the viscosity of the coating, while increasing the flexibility of the dry film and improving the adhesion of the coating. Adding NVP to radiation medical formulations can improve the elongation rate, viscosity, and other properties of high and low gloss coatings, allowing the coatings to form flexible and hard plastic films after curing, meeting various surface treatment requirements for plastic products.
(2) Preparation of plastic film
NVP can also participate in the preparation of plastic films with special properties. For example, when preparing plastic films that require good flexibility and compliance, the addition of NVP can improve the physical properties of the film, making it more suitable for specific application scenarios, such as packaging materials, electronic device protective films, etc.
Application in the Wood Industry
(1) UV resistant coating additive
In the wood industry, N-Vinyl-2-Pyrrolidone is often added to anti UV coatings. In the furniture industry, enhancing product performance, improving productivity, and reducing pressure on environmental pollution are the main motivations for using scatter coatings. In the wooden flooring industry, adding NVP to anti UV coatings can provide physical properties equivalent to those of wax free flooring. It can improve the adhesion and flexibility of coatings, allowing them to better adhere to the surface of wood, while enhancing the wood's resistance to ultraviolet radiation, prolonging the service life of wood products, and reducing problems such as wood fading and aging caused by ultraviolet radiation.
(2) Improve the performance of wood coating
In addition to improving UV resistance, NVP can also enhance other properties of wood coatings. For example, it can improve the wear resistance and water resistance of coatings, making wood products more durable in daily use and less susceptible to external environmental erosion.
(1) UB and EB curing coating additives
In the paper or cardboard industry, UB and EB curing coatings generally require low viscosity and high reactivity. NVP can meet these standards and maintain good curing properties by improving the flowability and measurement level of coatings. It can reduce the viscosity of the coating, making it easier to evenly apply the coating on the surface of the paper, improving coating efficiency and quality. At the same time, the addition of NVP can ensure that the coating has good reactivity during the curing process, forming a strong and smooth coating, and improving the physical properties of paper and cardboard.
(2) Dispersants and dyeing auxiliaries
NVP can also be used as a dispersant and dyeing assistant in the paper industry. As a dispersant, it can evenly disperse various additives and pigments in the pulp during the papermaking process, improving the quality and uniformity of the paper. As a dyeing aid, NVP can promote the binding of dyes with paper fibers, improve the dyeing effect and fastness, and give paper better color and visual effects.
Application in the metal industry
(1) UV coating active diluent
Metal UV coatings are generally formulated using cationic vinyl ether/epoxy chemistry or heterocyclic systems. The function of NVP is to crosslink with vinyl ether or acrylic functional groups in these systems to form an excellent and active diluent. It can reduce the viscosity of the coating, improve the flowability of the coating, and enable the coating to be better applied to metal surfaces. At the same time, the addition of NVP can enhance the adhesion between the coating and the metal surface, improve the wear resistance and corrosion resistance of the coating, and protect metal products from external environmental erosion.
(2) Metal surface treatment
NVP is also used in some metal surface treatment processes. For example, it can be used as a pretreatment agent for preparing metal surface coatings, improving the wettability and adhesion of metal surfaces, and providing a good foundation for subsequent coating construction.
(1) UV coating protective material
Electrical equipment manufacturers rely on NVP UV coating for rapid processing and low-temperature treatment to protect cables, electrical components, and printed circuit boards. NVP, as an active diluent for UV coatings, can improve the performance of coatings by forming a uniform and dense protective film after curing, effectively preventing cables, electrical components, and printed circuit boards from being damaged by external environments such as moisture, dust, chemicals, etc. At the same time, rapid processing and low-temperature processing also meet the requirements of the electronics industry for production efficiency and product quality.
(2) Preparation of electronic materials
N-Vinyl-2-Pyrrolidone also has certain applications in the preparation process of some electronic materials. For example, it can serve as a monomer for certain electronic polymer materials, participate in polymerization reactions, and prepare electronic materials with special properties for the manufacturing and packaging of electronic devices.
Application in the Ink Industry
(1) EB and UV curable ink additives
The packaging market utilizes EB and UV curing technologies to accelerate production speed and reduce energy consumption. The cured ink with NVP solvent added has excellent performance and less odor, occupying an important share in the screen ink market. NVP can improve the curing speed and effect of ink, enabling it to dry and cure quickly after printing, thereby enhancing printing efficiency and quality. At the same time, the low odor characteristic also improves the working environment of the printing workshop and reduces the impact on the health of operators.
(2) Improve ink performance
NVP can also improve other properties of ink, such as enhancing ink adhesion, wear resistance, and chemical resistance. It can better adhere ink to the printing substrate, making it less prone to detachment and wear, while also resisting the erosion of some chemicals, extending the service life of printed materials.
(1) Pharmaceutical intermediates
NVP can be used as a pharmaceutical intermediate for the synthesis of compounds such as drugs and pesticides. In drug synthesis, NVP can combine with other compounds through chemical reactions to form drug molecules with specific pharmacological activities. It can participate in various types of chemical reactions, such as addition reactions, substitution reactions, etc., providing possibilities for structural modification and activity optimization of drugs.
(2) Polyvinylpyrrolidone raw material
NVP is mainly used for the production of polyvinylpyrrolidone (PVP), which is widely used in the pharmaceutical industry. In pharmaceutical formulations, PVP can be used as a solvent, stabilizer, and enhancer to improve drug bioavailability. It can increase the solubility of drugs, improve their stability, and make them less prone to degradation and deterioration during storage and use. Meanwhile, PVP can also improve the drug release performance, enhance the bioavailability of drugs, and enable them to be better absorbed and utilized by the human body.
Application in the adhesive industry
(1) Curing adhesive active ingredient
The strict emission requirements and the need for a high curing rate have prompted the adhesive industry to develop a wide range of curing adhesives, among which the properties of NVP solvents can make adhesives naturally evaporate quickly or accelerate curing quickly using infrared radiation. NVP can be used as one of the active ingredients in adhesives to improve the curing speed and effectiveness of adhesives. It can react with other monomers or oligomers to form a polymer network structure with good adhesive properties, allowing the adhesive to quickly and firmly bond the adhered material together.
(2) Improve adhesive performance
NVP can also improve other properties of adhesives, such as increasing their flexibility, water resistance, and chemical resistance. It can make the adhesive better adapt to the deformation of the adhered object during the bonding process, improving the reliability and durability of the bonding.
(1) Dispersants and thickeners
In coatings, PVP (generated by NVP polymerization) can be used as a dispersant and thickener to improve the performance and stability of coatings. As a dispersant, PVP can evenly disperse pigments and fillers in coatings, prevent sedimentation and agglomeration of pigments and fillers, and improve the coverage and color brightness of coatings. As a thickener, PVP can increase the viscosity of coatings, improve the rheological properties of coatings, and provide good application performance during the construction process.
(2) Improve the water resistance and other properties of coatings
Although NVP itself has poor film-forming water retention and water resistance, in some specific coating systems, N-Vinyl-2-Pyrrolidone or its polymer PVP can also have a positive impact on the water resistance and other properties of the coating through reasonable ratio and modification treatment with other components. For example, in some water-based coatings, PVP can work synergistically with other film-forming substances to improve the density and water resistance of the coating.
Application in the field of cosmetics
(1) Adjust viscosity and improve texture
In cosmetics, NVP can be used to adjust viscosity, increase product consistency, and improve texture. It can serve as a thickener and rheology regulator for cosmetics, giving them appropriate viscosity and flowability for easy application and use. At the same time, NVP can also improve the skin feel of cosmetics, making them more delicate and smooth, and enhancing the user experience.
(2) Application of Polyvinylpyrrolidone
The PVP generated by NVP polymerization is also widely used in cosmetics. PVP has good film-forming and adsorption properties, which can form a protective film on the skin surface to prevent the loss of skin moisture and provide moisturizing effects. It can also adsorb oil and dirt on the surface of the skin, playing a role in cleaning and controlling oil.
N-vinylpyrrolidone, as an important organic compound, has a wide range of applications in various fields such as plastics, wood, papermaking, metals, inks, electronics, adhesives, pharmaceuticals, cosmetics, coatings, etc. Its unique chemical properties and excellent reactivity enable it to provide strong support for product performance improvement and process improvement in various fields. With the continuous progress of science and technology and the expansion of application fields, the application prospects of N-vinylpyrrolidone will be even broader.
Hot Tags: n-vinyl-2-pyrrolidone cas 88-12-0, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale